-
1
-
-
0033835996
-
Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease
-
Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Lieberburg I, Motter R, Nguyen M, Soriano F, Vasquez N, Weiss K, Welch B, Seubert P, Schenk D, Yednock T. 2000. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nat Med 6:916-919.
-
(2000)
Nat Med
, vol.6
, pp. 916-919
-
-
Bard, F.1
Cannon, C.2
Barbour, R.3
Burke, R.L.4
Games, D.5
Grajeda, H.6
Guido, T.7
Hu, K.8
Huang, J.9
Johnson-Wood, K.10
Khan, K.11
Kholodenko, D.12
Lee, M.13
Lieberburg, I.14
Motter, R.15
Nguyen, M.16
Soriano, F.17
Vasquez, N.18
Weiss, K.19
Welch, B.20
Seubert, P.21
Schenk, D.22
Yednock, T.23
more..
-
2
-
-
0034984469
-
Apoptotic neurons in Alzheimer's disease frequently show intracellular Aβ42 labeling
-
Chui DH, Dobo E, Makifuchi T, Akiyama H, Kawakatsu S, Checler F, Araki W, Takahashi K, Tabira T. 2001. Apoptotic neurons in Alzheimer's disease frequently show intracellular Aβ42 labeling. J Alzheimer Dis 3:231-239.
-
(2001)
J Alzheimer Dis
, vol.3
, pp. 231-239
-
-
Chui, D.H.1
Dobo, E.2
Makifuchi, T.3
Akiyama, H.4
Kawakatsu, S.5
Checler, F.6
Araki, W.7
Takahashi, K.8
Tabira, T.9
-
3
-
-
0031949628
-
A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1
-
Crook R, Verkkoniemi A, Perez-Tur J, Mehta N, Baker M, Houlden H, Farrer M, Hutton M, Lincoln S, Hardy J, Gwinn K, Somer M, Paetau A, Kalimo H, Ylikoski R, Poyhonen M, Kucera S, Haltia M. 1998. A variant of Alzheimer's disease with spastic paraparesis and unusual plaques due to deletion of exon 9 of presenilin 1. Nat Med 4:452-455.
-
(1998)
Nat Med
, vol.4
, pp. 452-455
-
-
Crook, R.1
Verkkoniemi, A.2
Perez-Tur, J.3
Mehta, N.4
Baker, M.5
Houlden, H.6
Farrer, M.7
Hutton, M.8
Lincoln, S.9
Hardy, J.10
Gwinn, K.11
Somer, M.12
Paetau, A.13
Kalimo, H.14
Ylikoski, R.15
Poyhonen, M.16
Kucera, S.17
Haltia, M.18
-
4
-
-
0021725392
-
Alzheimer's disease in identical twin brothers: Investigations of their family history and of clinical development of the disease
-
Doi A, Fujimoto K, Yoshida M, Tsuji K, Yamato A, Ii K, Hizawa K. 1984. Alzheimer's disease in identical twin brothers: Investigations of their family history and of clinical development of the disease. Seishin Shinkeigaku Zasshi 86:417-447.
-
(1984)
Seishin Shinkeigaku Zasshi
, vol.86
, pp. 417-447
-
-
Doi, A.1
Fujimoto, K.2
Yoshida, M.3
Tsuji, K.4
Yamato, A.5
Ii, K.6
Hizawa, K.7
-
5
-
-
0035845614
-
Reduced levels of amyloid beta-peptide antibody in Alzheimer disease
-
Du Y, Dodel R, Hampel H, Buerger K, Lin S, Eastwood B, Bales K, Gao F, Moeller HJ, Oertel W, Farlow M, Paul S. 2001. Reduced levels of amyloid beta-peptide antibody in Alzheimer disease. Neurology 57:801-805.
-
(2001)
Neurology
, vol.57
, pp. 801-805
-
-
Du, Y.1
Dodel, R.2
Hampel, H.3
Buerger, K.4
Lin, S.5
Eastwood, B.6
Bales, K.7
Gao, F.8
Moeller, H.J.9
Oertel, W.10
Farlow, M.11
Paul, S.12
-
6
-
-
0033762710
-
Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations
-
Houlden H, Baker M, McGowan E, Lewis P, Hutton M, Crook R, Wood NW, Kumar-Singh S, Geddes J, Swash M, Scaravilli F, Holton JL, Lashley T, Tomita T, Hashimoto T, Verkkoniemi A, Kalimo H, Somer M, Paetau A, Martin JJ, Van Broeckhoven C, Golde T, Hardy J, Haltia M, Revesz T. 2000. Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations. Ann Neurol 48:806-808.
-
(2000)
Ann Neurol
, vol.48
, pp. 806-808
-
-
Houlden, H.1
Baker, M.2
McGowan, E.3
Lewis, P.4
Hutton, M.5
Crook, R.6
Wood, N.W.7
Kumar-Singh, S.8
Geddes, J.9
Swash, M.10
Scaravilli, F.11
Holton, J.L.12
Lashley, T.13
Tomita, T.14
Hashimoto, T.15
Verkkoniemi, A.16
Kalimo, H.17
Somer, M.18
Paetau, A.19
Martin, J.J.20
Van Broeckhoven, C.21
Golde, T.22
Hardy, J.23
Haltia, M.24
Revesz, T.25
more..
-
7
-
-
8244260610
-
Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype
-
Kwok JBJ, Taddei K, Hallupp M, Fisher C, Brooks WS, Broe GA, Hardy J, Fulham MJ, Nicholson GA, Stell R, St. George Hyslop PH, Fraser PE, Kakulas B, Clarnette R, Relkin N, Gandy SE, Schofield PR, Martins RN. 1997. Two novel (M233T and R278T) presenilin-1 mutations in early-onset Alzheimer's disease pedigrees and preliminary evidence for association of presenilin-1 mutations with a novel phenotype. Neuroreport 8:1537-1542.
-
(1997)
Neuroreport
, vol.8
, pp. 1537-1542
-
-
Kwok, J.B.J.1
Taddei, K.2
Hallupp, M.3
Fisher, C.4
Brooks, W.S.5
Broe, G.A.6
Hardy, J.7
Fulham, M.J.8
Nicholson, G.A.9
Stell, R.10
St. George Hyslop, P.H.11
Fraser, P.E.12
Kakulas, B.13
Clarnette, R.14
Relkin, N.15
Gandy, S.E.16
Schofield, P.R.17
Martins, R.N.18
-
9
-
-
0034917266
-
Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques
-
Mann DMA, Takeuchi A, Sato S, Cairns NJ, Lantos PL, Rossor MN, Haltia M, Kalimo H, Iwatsubo T. 2001. Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic beta-amyloid pathology known as 'cotton wool' plaques. Neuropathol Appl Neurobiol 27:189-196.
-
(2001)
Neuropathol Appl Neurobiol
, vol.27
, pp. 189-196
-
-
Mann, D.M.A.1
Takeuchi, A.2
Sato, S.3
Cairns, N.J.4
Lantos, P.L.5
Rossor, M.N.6
Haltia, M.7
Kalimo, H.8
Iwatsubo, T.9
-
10
-
-
0014169286
-
A case of encephalopathy with plaque-like bodies, neurofibrillary change, angiopathy and amyotrophic lateral sclerosis-like lesions
-
Matsuoka T, Miyoshi K, Saka K, Kwagoe T, Nishikiori T, Suzuki S, Hirabayashi M, Shisozuka T, Suda K, Aoki A, Shimokawa K, Shiraki H. 1967. A case of encephalopathy with plaque-like bodies, neurofibrillary change, angiopathy and amyotrophic lateral sclerosis-like lesions. Adv Neurol Sci (Tokyo) 11:801-811.
-
(1967)
Adv Neurol Sci (Tokyo)
, vol.11
, pp. 801-811
-
-
Matsuoka, T.1
Miyoshi, K.2
Saka, K.3
Kwagoe, T.4
Nishikiori, T.5
Suzuki, S.6
Hirabayashi, M.7
Shisozuka, T.8
Suda, K.9
Aoki, A.10
Shimokawa, K.11
Shiraki, H.12
-
11
-
-
0035693924
-
Inflammation, autotoxicity and Alzheimer disease
-
McGeer PL, McGeer EG. 2001. Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging 22:799-809.
-
(2001)
Neurobiol Aging
, vol.22
, pp. 799-809
-
-
McGeer, P.L.1
McGeer, E.G.2
-
12
-
-
0031594142
-
Increased Aβ42(43) from cell lines expressing presenilin 1 mutations
-
Mehta ND, Refolo LM, Eckman C, Sanders S, Yager D, Perez-Tur J, Younkin S, Duff K, Hardy J, Hutton M. 1998. Increased Aβ42(43) from cell lines expressing presenilin 1 mutations. Ann Neurol 43:256-258.
-
(1998)
Ann Neurol
, vol.43
, pp. 256-258
-
-
Mehta, N.D.1
Refolo, L.M.2
Eckman, C.3
Sanders, S.4
Yager, D.5
Perez-Tur, J.6
Younkin, S.7
Duff, K.8
Hardy, J.9
Hutton, M.10
-
13
-
-
0011119656
-
Early onset Alzheimer's disease? A case of encephalopathy mainly presenting senile plaque-like lesions
-
Mizushima S, Yamada H. 1974. Early onset Alzheimer's disease? A case of encephalopathy mainly presenting senile plaque-like lesions [Abstract only in Japanese]. Adv Neurol Sci (Tokyo) 18:206-207.
-
(1974)
Adv Neurol Sci (Tokyo)
, vol.18
, pp. 206-207
-
-
Mizushima, S.1
Yamada, H.2
-
14
-
-
0035964312
-
Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: Implications for the pathogenesis and treatment of Alzheimer's disease
-
Monsonego A, Maron R, Zota V, Selkoe DJ, Weiner HL. 2001. Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: Implications for the pathogenesis and treatment of Alzheimer's disease. Proc Natl Acad Sci USA 98:10273-10278.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10273-10278
-
-
Monsonego, A.1
Maron, R.2
Zota, V.3
Selkoe, D.J.4
Weiner, H.L.5
-
15
-
-
0032828163
-
Alzheimer disease PS-1 exon 9 deletion defined
-
Prihar G, Verkkoniem A, Perez-Tur J, Crook R, Lincoln S, Houlden H, Somer M, Paetau A, Kalimo H, Grover A, Myllykangas L, Hutton M, Hardy J, Haltia M. 1999. Alzheimer disease PS-1 exon 9 deletion defined. Nat Med 5:1090.
-
(1999)
Nat Med
, vol.5
, pp. 1090
-
-
Prihar, G.1
Verkkoniem, A.2
Perez-Tur, J.3
Crook, R.4
Lincoln, S.5
Houlden, H.6
Somer, M.7
Paetau, A.8
Kalimo, H.9
Grover, A.10
Myllykangas, L.11
Hutton, M.12
Hardy, J.13
Haltia, M.14
-
16
-
-
0031975957
-
Splicing mutation of presenilin-1 gene for early-onset familial Alzheimer's disease
-
Sato S, Kamino K, Miki T, Doi A, Ii K, St. George-Hyslop PH, Ogihara T, Sakaki Y. 1998. Splicing mutation of presenilin-1 gene for early-onset familial Alzheimer's disease. Hum Mutat 1(Suppl):91-94.
-
(1998)
Hum Mutat
, vol.1
, Issue.SUPPL.
, pp. 91-94
-
-
Sato, S.1
Kamino, K.2
Miki, T.3
Doi, A.4
Ii, K.5
St. George-Hyslop, P.H.6
Ogihara, T.7
Sakaki, Y.8
-
17
-
-
0033536163
-
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P. 1999. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400:173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
18
-
-
0035115610
-
Variable phenotype of Alzheimer's disease with spastic paraparesis
-
Smith MJ, Kwok JB, McLean CA, Kril JJ, Broe GA, Nicholson GA, Cappai R, Hallupp M, Cotton RG, Masters CL, Schofield PR, Brooks WS. 2001. Variable phenotype of Alzheimer's disease with spastic paraparesis. Ann Neurol 49:125-129.
-
(2001)
Ann Neurol
, vol.49
, pp. 125-129
-
-
Smith, M.J.1
Kwok, J.B.2
McLean, C.A.3
Kril, J.J.4
Broe, G.A.5
Nicholson, G.A.6
Cappai, R.7
Hallupp, M.8
Cotton, R.G.9
Masters, C.L.10
Schofield, P.R.11
Brooks, W.S.12
-
19
-
-
0035831499
-
A pathogenic presenilin-1 deletion causes aberrant Aβ 42 production in the absence of congophilic amyloid plaques
-
Steiner H, Revesz T, Neumann M, Romig H, Grim MG, Pesold B, Kretzschmar HA, Hardy J, Holton JL, Baumeister R, Houlden H, Haass C. 2001. A pathogenic presenilin-1 deletion causes aberrant Aβ 42 production in the absence of congophilic amyloid plaques. J Biol Chem 276:7233-7239.
-
(2001)
J Biol Chem
, vol.276
, pp. 7233-7239
-
-
Steiner, H.1
Revesz, T.2
Neumann, M.3
Romig, H.4
Grim, M.G.5
Pesold, B.6
Kretzschmar, H.A.7
Hardy, J.8
Holton, J.L.9
Baumeister, R.10
Houlden, H.11
Haass, C.12
-
20
-
-
0036550597
-
Significance of intracellular Aβ42 accumulation in Alzheimer's disease
-
Tabira T, Chui DH, Kuroda S. 2002. Significance of intracellular Aβ42 accumulation in Alzheimer's disease. Front Biosci 7:44-49.
-
(2002)
Front Biosci
, vol.7
, pp. 44-49
-
-
Tabira, T.1
Chui, D.H.2
Kuroda, S.3
-
21
-
-
0034646249
-
Variant Alzheimer's disease with spastic paraparesis: Clinical characterization
-
Verkkoniemi A, Somer M, Rinne JO, Myllykangas L, Crook R, Hardy J, Viitanen M, Kalimo H, Haltia M. 2000. Variant Alzheimer's disease with spastic paraparesis: Clinical characterization. Neurology 54:1103-1109.
-
(2000)
Neurology
, vol.54
, pp. 1103-1109
-
-
Verkkoniemi, A.1
Somer, M.2
Rinne, J.O.3
Myllykangas, L.4
Crook, R.5
Hardy, J.6
Viitanen, M.7
Kalimo, H.8
Haltia, M.9
|