Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic β-amyloid pathology known as 'cotton wool' plaques

Neuropathology and Applied Neurobiology

Volumn 27, Issue 3, 2001, Pages 189-196

  Mann, D M A ^a   Takeuchi, A ^b   Sato, S ^b   Cairns, N J ^c   Lantos, P L ^c   Rossor, M N ^d   Haltia, M ^e   Kalimo, H ^f   Iwatsubo, T ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF TOKYO   (Japan)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^e UNIVERSITY OF HELSINKI   (Finland)

^f UNIVERSITY OF TURKU   (Finland)

Author keywords

amyloid; Alzheimer's disease; Mutation; Presenilin 1 gene; Senile plaque

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; PRESENILIN 1;

ADULT; ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTAL CORTEX; GENE DELETION; GENOTYPE; HUMAN; HUMAN TISSUE; MALE; NEURITE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SENILE PLAQUE;

ADULT; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CEREBELLUM; EXONS; FEMALE; FRONTAL LOBE; GENE DELETION; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; PEPTIDE FRAGMENTS; PRESENILIN-1;

EID: 0034917266     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2990.2001.00316.x     Document Type: Article

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