Systematic genetic study of Alzheimer disease in Latin America: Mutation frequencies of the amyloid β precursor protein and presenilin genes in Colombia

American Journal of Medical Genetics

Volumn 103, Issue 2, 2001, Pages 138-143

  Arango, Diana ^a,b   Cruts, Marc ^b   Torres, Orlando ^a   Backhovens, Hubert ^b   Serrano, Martha L ^a   Villareal, Elsa ^a   Montañes, Patricia ^c   Matallana, Diana ^c   Cano, Carlos ^c   Van Broeckhoven, Christine ^b   Jacquier, Martine ^a  

^a INSTITUTO NACIONAL DE SALUD   (Colombia)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c PONTIFICIA UNIVERSIDAD JAVERIANA   (Colombia)

Author keywords

Alzheimer disease; APP; E280A; E318G; G708; I143T; Mutation analysis; P129; PSEN1; PSEN2; S236; V94M

Indexed keywords

AMYLOID BETA PROTEIN; PRESENILIN 1; PRESENILIN 2;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ANALYSIS; GENETIC POLYMORPHISM; HUMAN; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; ONSET AGE; PRIORITY JOURNAL; SOUTH AND CENTRAL AMERICA;

AGE OF ONSET; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN PRECURSOR; BASE SEQUENCE; COLOMBIA; DNA; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; HUMANS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; POINT MUTATION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; PRESENILIN-1; PRESENILIN-2; PROTEINS;

EID: 0035479323     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-8628(20011001)103:2<138::AID-AJMG1529>3.0.CO;2-8     Document Type: Article

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