Familial Alzheimer's disease: Site of mutation influences clinical phenotype

Annals of Neurology

Volumn 48, Issue 3, 2000, Pages 376-379

  Lippa, C F ^a   Swearer, J M ^b   Kane, K J ^b   Nochlin, D ^c   Bird, T D ^c   Ghetti, B ^d   Nee, L E ^e   St George Hyslop, P ^f   Pollen, D A ^b   Drachman, D A ^b  

^a DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d INDIANA UNIVERSITY   (United States)

^e NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FAMILIAL DISEASE; GENE EXPRESSION; GENE MUTATION; GENETIC LINKAGE; GENOTYPE; HEREDITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MORTALITY; ONSET AGE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

ADULT; AGE OF ONSET; AGED; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANALYSIS OF VARIANCE; HUMANS; MEMBRANE PROTEINS; MIDDLE AGED; MUTATION; PHENOTYPE; PRESENILIN-1; PRESENILIN-2;

EID: 0033848935     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(200009)48:3<376::AID-ANA13>3.0.CO;2-U     Document Type: Article

References (11)

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6. Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology
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10. Epistatic effect of APP 717: Mutation and apolipoprotein E genotype in familial Alzheimer's disease
11. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families