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Volumn 107, Issue 4, 2006, Pages 1265-1275

Designer blood: Creating hematopoietic lineages from embryonic stem cells

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ADULTHOOD; ANIMAL CELL; B LYMPHOCYTE; BLOOD CELL; BLOOD DISEASE; CELL CULTURE; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINE; CELL LINEAGE; CELL MATURATION; CELL POPULATION; CELL TRANSPLANTATION; CELL TYPE; DENDRITIC CELL; EMBRYO; EMBRYONIC STEM CELL; EOSINOPHIL; ERYTHROID CELL; GRANULOCYTE; HEMATOPOIETIC STEM CELL; HOST; HUMAN; HUMAN CELL; IN VITRO STUDY; MACROPHAGE; MAST CELL; MEGAKARYOCYTE; MOUSE; NATURAL KILLER CELL; NONHUMAN; ONTOGENY; OSTEOCLAST; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

EID: 32644448944     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2005-09-3621     Document Type: Review
Times cited : (66)

References (188)
  • 1
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292:154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 2
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • U S A
    • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A. 1981;78:7634-7638.
    • (1981) Proc Natl Acad Sci , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 3
    • 0021358883 scopus 로고
    • Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
    • Bradley A, Evans M, Kaufman MH, Robertson E. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. Nature. 1984;309:255-256.
    • (1984) Nature , vol.309 , pp. 255-256
    • Bradley, A.1    Evans, M.2    Kaufman, M.H.3    Robertson, E.4
  • 4
    • 11144223157 scopus 로고    scopus 로고
    • Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells
    • Rao M. Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells. Dev Biol. 2004;275:269-286.
    • (2004) Dev Biol , vol.275 , pp. 269-286
    • Rao, M.1
  • 5
    • 6044269157 scopus 로고    scopus 로고
    • Self-renewal of teratocarcinoma and embryonic stem cells
    • Chambers I, Smith A. Self-renewal of teratocarcinoma and embryonic stem cells. Oncogene. 2004;23:7150-7160.
    • (2004) Oncogene , vol.23 , pp. 7150-7160
    • Chambers, I.1    Smith, A.2
  • 6
    • 0024205842 scopus 로고
    • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells
    • Williams RL, Hilton DJ, Pease S, et al. Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells. Nature. 1988;336:684-687.
    • (1988) Nature , vol.336 , pp. 684-687
    • Williams, R.L.1    Hilton, D.J.2    Pease, S.3
  • 7
    • 0344845415 scopus 로고    scopus 로고
    • BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
    • Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell. 2003;115:281-292.
    • (2003) Cell , vol.115 , pp. 281-292
    • Ying, Q.L.1    Nichols, J.2    Chambers, I.3    Smith, A.4
  • 8
    • 1942533517 scopus 로고    scopus 로고
    • BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways
    • U S A
    • Qi X, Li TG, Hao J, et al. BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc Natl Acad Sci U S A. 2004;101:6027-6032.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 6027-6032
    • Qi, X.1    Li, T.G.2    Hao, J.3
  • 9
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cell lines derived from human blastocysts. Science. 1998;282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 10
    • 4444309648 scopus 로고    scopus 로고
    • LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells
    • Daheron L, Opitz SL, Zaehres H, et al. LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells. Stem Cells. 2004;22:770-778.
    • (2004) Stem Cells , vol.22 , pp. 770-778
    • Daheron, L.1    Opitz, S.L.2    Zaehres, H.3
  • 11
    • 3542996260 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human embryonic stem cells is STAT3 independent
    • Humphrey RK, Beattie GM, Lopez AD, et al. Maintenance of pluripotency in human embryonic stem cells is STAT3 independent. Stem Cells. 2004;22:522-530.
    • (2004) Stem Cells , vol.22 , pp. 522-530
    • Humphrey, R.K.1    Beattie, G.M.2    Lopez, A.D.3
  • 12
    • 10344238022 scopus 로고    scopus 로고
    • Human embryonic stem cells: Prospects for development
    • Pera MF, Trounson AO. Human embryonic stem cells: prospects for development. Development. 2004;131:5515-5525.
    • (2004) Development , vol.131 , pp. 5515-5525
    • Pera, M.F.1    Trounson, A.O.2
  • 13
    • 22844433072 scopus 로고    scopus 로고
    • Fifteen tips and tricks for human embryonic stem cells
    • Perkel J. Fifteen tips and tricks for human embryonic stem cells. The Scientist. 2005;19:18-19.
    • (2005) The Scientist , vol.19 , pp. 18-19
    • Perkel, J.1
  • 14
    • 32644444188 scopus 로고    scopus 로고
    • Stem Cells: An emerging portrait. Struggling to sharpen the lines that define embryonic stem cells
    • Lewis R. Stem Cells: an emerging portrait. Struggling to sharpen the lines that define embryonic stem cells. The Scientist. 2005;19:15-17.
    • (2005) The Scientist , vol.19 , pp. 15-17
    • Lewis, R.1
  • 15
    • 19944389856 scopus 로고    scopus 로고
    • Available human feeder cells for the maintenance of human embryonic stem cells
    • Lee JB, Song JM, Lee JE, et al. Available human feeder cells for the maintenance of human embryonic stem cells. Reproduction. 2004;128:727-735.
    • (2004) Reproduction , vol.128 , pp. 727-735
    • Lee, J.B.1    Song, J.M.2    Lee, J.E.3
  • 16
    • 8744295665 scopus 로고    scopus 로고
    • Expansion of pluripotent human embryonic stem cells on human feeders
    • Choo AB, Padmanabhan J, Chin AC, Oh SK. Expansion of pluripotent human embryonic stem cells on human feeders. Biotechnol Bioeng. 2004;88:321-331.
    • (2004) Biotechnol Bioeng , vol.88 , pp. 321-331
    • Choo, A.B.1    Padmanabhan, J.2    Chin, A.C.3    Oh, S.K.4
  • 17
    • 20444375784 scopus 로고    scopus 로고
    • Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development
    • Wang L, Li L, Menendez P, Cerdan C, Bhatia M. Human embryonic stem cells maintained in the absence of mouse embryonic fibroblasts or conditioned media are capable of hematopoietic development. Blood. 2005;105:4598-4603.
    • (2005) Blood , vol.105 , pp. 4598-4603
    • Wang, L.1    Li, L.2    Menendez, P.3    Cerdan, C.4    Bhatia, M.5
  • 18
    • 16444373230 scopus 로고    scopus 로고
    • Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers
    • Beattie GM, Lopez AD, Bucay N, et al. Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers. Stem Cells. 2005;23:489-495.
    • (2005) Stem Cells , vol.23 , pp. 489-495
    • Beattie, G.M.1    Lopez, A.D.2    Bucay, N.3
  • 19
    • 0942298178 scopus 로고    scopus 로고
    • Long-term culture of human embryonic stem cells in feeder-free conditions
    • Rosler ES, Fisk GJ, Ares X, et al. Long-term culture of human embryonic stem cells in feeder-free conditions. Dev Dyn. 2004;229:259-274.
    • (2004) Dev Dyn , vol.229 , pp. 259-274
    • Rosler, E.S.1    Fisk, G.J.2    Ares, X.3
  • 21
    • 13744252631 scopus 로고    scopus 로고
    • Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state
    • Wei CL, Miura T, Robson P, et al. Transcriptome profiling of human and murine ESCs identifies divergent paths required to maintain the stem cell state. Stem Cells. 2005;23:166-185.
    • (2005) Stem Cells , vol.23 , pp. 166-185
    • Wei, C.L.1    Miura, T.2    Robson, P.3
  • 22
    • 1242267927 scopus 로고    scopus 로고
    • Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
    • Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med. 2004;10:55-63.
    • (2004) Nat Med , vol.10 , pp. 55-63
    • Sato, N.1    Meijer, L.2    Skaltsounis, L.3    Greengard, P.4    Brivanlou, A.H.5
  • 23
    • 28444438841 scopus 로고    scopus 로고
    • Defining the role of Wnt/{beta}-catenin signaling in the survival, proliferation and self-renewal of human embryonic stem cells
    • Dravid G, Ye Z, Hammond H, et al. Defining the role of Wnt/{beta}-catenin signaling in the survival, proliferation and self-renewal of human embryonic stem cells. Stem Cells. 2005;23:1489-1501.
    • (2005) Stem Cells , vol.23 , pp. 1489-1501
    • Dravid, G.1    Ye, Z.2    Hammond, H.3
  • 24
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet. 2000;24:372-376.
    • (2000) Nat Genet , vol.24 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.2    Smith, A.G.3
  • 25
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • Chambers I, Colby D, Robertson M, et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell. 2003;113:643-655.
    • (2003) Cell , vol.113 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3
  • 26
    • 0942276446 scopus 로고    scopus 로고
    • Properties of four human embryonic stem cell lines maintained in a feeder-free culture system
    • Carpenter MK, Rosler ES, Fisk GJ, et al. Properties of four human embryonic stem cell lines maintained in a feeder-free culture system. Dev Dyn. 2004;229:243-258.
    • (2004) Dev Dyn , vol.229 , pp. 243-258
    • Carpenter, M.K.1    Rosler, E.S.2    Fisk, G.J.3
  • 27
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 2005;122:947-956.
    • (2005) Cell , vol.122 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3
  • 28
    • 33645527040 scopus 로고    scopus 로고
    • Unique gene expression signature by human embryonic stem cells cultured under serum free conditions correlates with their enhanced and prolonged growth in an undifferentiated stage
    • In press
    • Skottman H, Stromberg AM, Matilainen E, Inzunza J, Hovatta O, Lahesmaa R. Unique gene expression signature by human embryonic stem cells cultured under serum free conditions correlates with their enhanced and prolonged growth in an undifferentiated stage. Stem Cells. In press.
    • Stem Cells
    • Skottman, H.1    Stromberg, A.M.2    Matilainen, E.3    Inzunza, J.4    Hovatta, O.5    Lahesmaa, R.6
  • 29
    • 27144536312 scopus 로고    scopus 로고
    • Gene expression signatures of seven individual human embryonic stem cell lines
    • Skottman H, Mikkola M, Lundin K, et al. Gene expression signatures of seven individual human embryonic stem cell lines. Stem Cells. 2005;23:1343-1356.
    • (2005) Stem Cells , vol.23 , pp. 1343-1356
    • Skottman, H.1    Mikkola, M.2    Lundin, K.3
  • 30
    • 19944429407 scopus 로고    scopus 로고
    • Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan
    • Miura T, Luo Y, Khrebtukova I, et al. Monitoring early differentiation events in human embryonic stem cells by massively parallel signature sequencing and expressed sequence tag scan. Stem Cells Dev. 2004;13:694-715.
    • (2004) Stem Cells Dev , vol.13 , pp. 694-715
    • Miura, T.1    Luo, Y.2    Khrebtukova, I.3
  • 33
    • 0041560908 scopus 로고    scopus 로고
    • Molecular signature of human embryonic stem cells and its comparison with the mouse
    • Sato N, Sanjuan IM, Heke M, Uchida M, Naef F, Brivanlou AH. Molecular signature of human embryonic stem cells and its comparison with the mouse. Dev Biol. 2003;260:404-413.
    • (2003) Dev Biol , vol.260 , pp. 404-413
    • Sato, N.1    Sanjuan, I.M.2    Heke, M.3    Uchida, M.4    Naef, F.5    Brivanlou, A.H.6
  • 35
    • 11144355188 scopus 로고    scopus 로고
    • Gene expression in human embryonic stem cell lines: Unique molecular signature
    • Bhattacharya B, Miura T, Brandenberger R, et al. Gene expression in human embryonic stem cell lines: unique molecular signature. Blood. 2004;103:2956-2964.
    • (2004) Blood , vol.103 , pp. 2956-2964
    • Bhattacharya, B.1    Miura, T.2    Brandenberger, R.3
  • 36
    • 0346250854 scopus 로고    scopus 로고
    • The transcriptome profile of human embryonic stem cells as defined by SAGE
    • Richards M, Tan SP, Tan JH, Chan WK, Bongso A. The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells. 2004;22:51-64.
    • (2004) Stem Cells , vol.22 , pp. 51-64
    • Richards, M.1    Tan, S.P.2    Tan, J.H.3    Chan, W.K.4    Bongso, A.5
  • 37
    • 0347481207 scopus 로고    scopus 로고
    • In vitro differentiation of mouse embryonic stem cells to hematopoietic cells on an OP9 stromal cell monolayer
    • Kitajima K, Tanaka M, Zheng J, Sakai-Ogawa E, Nakano T. In vitro differentiation of mouse embryonic stem cells to hematopoietic cells on an OP9 stromal cell monolayer. Methods Enzymol. 2003;365:72-83.
    • (2003) Methods Enzymol , vol.365 , pp. 72-83
    • Kitajima, K.1    Tanaka, M.2    Zheng, J.3    Sakai-Ogawa, E.4    Nakano, T.5
  • 38
    • 0346850640 scopus 로고    scopus 로고
    • Hematopoietic commitment of ES cells in culture
    • Kennedy M, Keller GM. Hematopoietic commitment of ES cells in culture. Methods Enzymol. 2003;365:39-59.
    • (2003) Methods Enzymol , vol.365 , pp. 39-59
    • Kennedy, M.1    Keller, G.M.2
  • 39
    • 0346220083 scopus 로고    scopus 로고
    • In vitro differentiation of mouse embryonic stem cells: Hematopoietic and vascular cell types
    • Fraser ST, Yamashita J, Jakt LM, Okada M, Ogawa M, Nishikawa S. In vitro differentiation of mouse embryonic stem cells: hematopoietic and vascular cell types. Methods Enzymol. 2003;365:59-72.
    • (2003) Methods Enzymol , vol.365 , pp. 59-72
    • Fraser, S.T.1    Yamashita, J.2    Jakt, L.M.3    Okada, M.4    Ogawa, M.5    Nishikawa, S.6
  • 40
    • 0034177522 scopus 로고    scopus 로고
    • Vascular endothelial growth factor synergistically enhances bone morphogenetic protein-4-dependent lymphohematopoietic cell generation from embryonic stem cells in vitro
    • Nakayama N, Lee J, Chiu L. Vascular endothelial growth factor synergistically enhances bone morphogenetic protein-4-dependent lymphohematopoietic cell generation from embryonic stem cells in vitro. Blood. 2000;95:2275-2283.
    • (2000) Blood , vol.95 , pp. 2275-2283
    • Nakayama, N.1    Lee, J.2    Chiu, L.3
  • 41
    • 3042733135 scopus 로고    scopus 로고
    • A hierarchical order of factors in the generation of FLK1- And SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells
    • Park C, Afrikanova I, Chung YS, et al. A hierarchical order of factors in the generation of FLK1- and SCL-expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development. 2004;131:2749-2762.
    • (2004) Development , vol.131 , pp. 2749-2762
    • Park, C.1    Afrikanova, I.2    Chung, Y.S.3
  • 42
    • 0037871588 scopus 로고    scopus 로고
    • Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells
    • Chadwick K, Wang L, Li L, et al. Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood. 2003;102:906-915.
    • (2003) Blood , vol.102 , pp. 906-915
    • Chadwick, K.1    Wang, L.2    Li, L.3
  • 43
    • 8444237836 scopus 로고    scopus 로고
    • Dorsal-ventral patterning and neural induction in Xenopus embryos
    • De Robertis EM, Kuroda H. Dorsal-ventral patterning and neural induction in Xenopus embryos. Annu Rev Cell Dev Biol. 2004;20:285-308.
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 285-308
    • De Robertis, E.M.1    Kuroda, H.2
  • 44
    • 0034797086 scopus 로고    scopus 로고
    • Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate embryogenesis
    • Tiedemann H, Asashima M, Grunz H, Knochel W. Pluripotent cells (stem cells) and their determination and differentiation in early vertebrate embryogenesis. Dev Growth Differ. 2001;43:469-502.
    • (2001) Dev Growth Differ , vol.43 , pp. 469-502
    • Tiedemann, H.1    Asashima, M.2    Grunz, H.3    Knochel, W.4
  • 45
    • 0027389676 scopus 로고
    • Hematopoietic commitment during embryonic stem cell differentiation in culture
    • Keller G, Kennedy M, Papayannopoulou T, Wiles MV. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol. 1993;13:473-486.
    • (1993) Mol Cell Biol , vol.13 , pp. 473-486
    • Keller, G.1    Kennedy, M.2    Papayannopoulou, T.3    Wiles, M.V.4
  • 46
    • 0021891053 scopus 로고
    • The in vitro development of blastocystderived embryonic stem cell lines: Formation of visceral yolk sac, blood islands and myocardium
    • Doetschman TC, Eistetter H, Katz M, Schmidt W, Kemler R. The in vitro development of blastocystderived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium. J Embryol Exp Morphol. 1985;87:27-45.
    • (1985) J Embryol Exp Morphol , vol.87 , pp. 27-45
    • Doetschman, T.C.1    Eistetter, H.2    Katz, M.3    Schmidt, W.4    Kemler, R.5
  • 47
    • 0028048369 scopus 로고
    • Generation of lymphohematopoietic cells from embryonic stem cells in culture
    • Nakano T, Kodama H, Honjo T. Generation of lymphohematopoietic cells from embryonic stem cells in culture. Science. 1994;265:1098-1101.
    • (1994) Science , vol.265 , pp. 1098-1101
    • Nakano, T.1    Kodama, H.2    Honjo, T.3
  • 48
    • 0025975926 scopus 로고
    • Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture
    • Wiles MV, Keller G. Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture. Development. 1991;111:259-267.
    • (1991) Development , vol.111 , pp. 259-267
    • Wiles, M.V.1    Keller, G.2
  • 49
    • 0025910382 scopus 로고
    • Early fetal hematopoietic development from in vitro differentiated embryonic stem cells
    • Burkert U, vonRuden RT, Wagner EF. Early fetal hematopoietic development from in vitro differentiated embryonic stem cells. New Biol. 1991;3:698-708.
    • (1991) New Biol , vol.3 , pp. 698-708
    • Burkert, U.1    VonRuden, R.T.2    Wagner, E.F.3
  • 50
    • 0025732077 scopus 로고
    • Hematopoietic development of embryonic stem cells in vitro: Cytokine and receptor gene expression
    • Schmitt RM, Bruyns E, Snodgrass HR. Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression. Genes Dev. 1991;5:728-740.
    • (1991) Genes Dev , vol.5 , pp. 728-740
    • Schmitt, R.M.1    Bruyns, E.2    Snodgrass, H.R.3
  • 51
    • 0030970178 scopus 로고    scopus 로고
    • In vitro differentiation of embryonic stem cells: Immunophenotypic analysis of cultured embryoid bodies
    • Ling V, Neben S. In vitro differentiation of embryonic stem cells: immunophenotypic analysis of cultured embryoid bodies. J Cell Physiol. 1997;172:171-182.
    • (1997) J Cell Physiol , vol.172 , pp. 171-182
    • Ling, V.1    Neben, S.2
  • 52
    • 0036339997 scopus 로고    scopus 로고
    • Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells
    • Mitjavila-Garcia MT, Cailleret M, Godin I, et al. Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells. Development. 2002;129:2003-2013.
    • (2002) Development , vol.129 , pp. 2003-2013
    • Mitjavila-Garcia, M.T.1    Cailleret, M.2    Godin, I.3
  • 53
    • 0030560983 scopus 로고    scopus 로고
    • In vitro development of hematopoietic system from mouse embryonic stem cells: A new approach for embryonic hematopoiesis
    • Nakano T. In vitro development of hematopoietic system from mouse embryonic stem cells: a new approach for embryonic hematopoiesis. Int J Hematol. 1996;65:1-8.
    • (1996) Int J Hematol , vol.65 , pp. 1-8
    • Nakano, T.1
  • 54
    • 11144248097 scopus 로고    scopus 로고
    • Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions
    • Zhang WJ, Park C, Arentson E, Choi K. Modulation of hematopoietic and endothelial cell differentiation from mouse embryonic stem cells by different culture conditions. Blood. 2005;105:111-114.
    • (2005) Blood , vol.105 , pp. 111-114
    • Zhang, W.J.1    Park, C.2    Arentson, E.3    Choi, K.4
  • 55
    • 25144517264 scopus 로고    scopus 로고
    • In vitro hematopoietic differentiation of human embryonic stem cells induced by co-culture with human bone marrow stromal cells and low dose cytokines
    • Wang J, Zhao HP, Lin G, et al. In vitro hematopoietic differentiation of human embryonic stem cells induced by co-culture with human bone marrow stromal cells and low dose cytokines. Cell Biol Int. 2005;29:654-661.
    • (2005) Cell Biol Int , vol.29 , pp. 654-661
    • Wang, J.1    Zhao, H.P.2    Lin, G.3
  • 56
    • 14844341800 scopus 로고    scopus 로고
    • Characterization of the interactions between stromal and haematopoietic progenitor cells in expansion cell culture models
    • Bilko NM, Votyakova IA, Vasylovska SV, Bilko DI. Characterization of the interactions between stromal and haematopoietic progenitor cells in expansion cell culture models. Cell Biol Int. 2005;29:83-86.
    • (2005) Cell Biol Int , vol.29 , pp. 83-86
    • Bilko, N.M.1    Votyakova, I.A.2    Vasylovska, S.V.3    Bilko, D.I.4
  • 58
    • 8744240173 scopus 로고    scopus 로고
    • Three-dimensional porous alginate scaffolds provide a conducive environment for generation of well-vascularized embryoid bodies from human embryonic stem cells
    • Gerecht-Nir S, Cohen S, Ziskind A, Itskovitz-Eldor J. Three-dimensional porous alginate scaffolds provide a conducive environment for generation of well-vascularized embryoid bodies from human embryonic stem cells. Biotechnol Bioeng. 2004;88:313-320.
    • (2004) Biotechnol Bioeng , vol.88 , pp. 313-320
    • Gerecht-Nir, S.1    Cohen, S.2    Ziskind, A.3    Itskovitz-Eldor, J.4
  • 59
    • 17144424618 scopus 로고    scopus 로고
    • Biomimetic three-dimensional cultures significantly increase hematopoietic differentiation efficacy of embryonic stem cells
    • Liu H, Roy K. Biomimetic three-dimensional cultures significantly increase hematopoietic differentiation efficacy of embryonic stem cells. Tissue Eng. 2005;11:319-330.
    • (2005) Tissue Eng , vol.11 , pp. 319-330
    • Liu, H.1    Roy, K.2
  • 61
    • 0033405452 scopus 로고    scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J, Robertson S, Kennedy M, Wall C, Keller G. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development. 1999;126:5073-5084.
    • (1999) Development , vol.126 , pp. 5073-5084
    • Palis, J.1    Robertson, S.2    Kennedy, M.3    Wall, C.4    Keller, G.5
  • 63
    • 0018625422 scopus 로고
    • Hereditary anemias of the mouse: A review for geneticists
    • Russel E. Hereditary anemias of the mouse: a review for geneticists. Adv Genet. 1979;20:357-459.
    • (1979) Adv Genet , vol.20 , pp. 357-459
    • Russel, E.1
  • 64
    • 0010533123 scopus 로고
    • Erythropoiesis and haemoglobin production during development
    • Jones CT, ed. New York, NY: Elsevier Biomedical Press
    • Wood WG. Erythropoiesis and haemoglobin production during development. In: Jones CT, ed. Biochemical Development of the Fetus and Neonate. New York, NY: Elsevier Biomedical Press; 1982:127-162.
    • (1982) Biochemical Development of the Fetus and Neonate , pp. 127-162
    • Wood, W.G.1
  • 66
  • 67
    • 0014744817 scopus 로고
    • Ontogeny of the haemopoietic system: Yolk sac origin of in vivo and in vitro colony forming cells in the developing embryo
    • Moore MAS, Metcalf D. Ontogeny of the haemopoietic system: yolk sac origin of in vivo and in vitro colony forming cells in the developing embryo. Br J Hematol. 1970;18:279-296.
    • (1970) Br J Hematol , vol.18 , pp. 279-296
    • Moore, M.A.S.1    Metcalf, D.2
  • 68
    • 0015072078 scopus 로고
    • A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse
    • Haar JL, Ackerman GA. A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse. Anat Rec. 1971;170:199-224.
    • (1971) Anat Rec , vol.170 , pp. 199-224
    • Haar, J.L.1    Ackerman, G.A.2
  • 69
    • 0000462980 scopus 로고
    • Studies on the origin of the blood vessels and of red blood corpuscles as seen in the living blastoderm of chick during the second day of incubation
    • Sabin FR. Studies on the origin of the blood vessels and of red blood corpuscles as seen in the living blastoderm of chick during the second day of incubation. Contrib Embryol. 1920;9:215-262.
    • (1920) Contrib Embryol , vol.9 , pp. 215-262
    • Sabin, F.R.1
  • 70
    • 0001652231 scopus 로고
    • The development of in vitro of the blood of the early chick embryo
    • Murray PDF. The development of in vitro of the blood of the early chick embryo. Proc R Soc Lond B Biol Sci. 1932;11:497-521.
    • (1932) Proc R Soc Lond B Biol Sci , vol.11 , pp. 497-521
    • Murray, P.D.F.1
  • 71
    • 0030942527 scopus 로고    scopus 로고
    • A common precursor for primitive erythropoiesis and definitive haematopoiesis
    • Kennedy M, Firpo M, Choi K, et al. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature. 1997;386:488-493.
    • (1997) Nature , vol.386 , pp. 488-493
    • Kennedy, M.1    Firpo, M.2    Choi, K.3
  • 73
    • 0031833476 scopus 로고    scopus 로고
    • Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages
    • Nishikawa SI, Nishikawa S, Hirashima M, Matsuyoshi N, Kodama H. Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages. Development. 1998;125:1747-1757.
    • (1998) Development , vol.125 , pp. 1747-1757
    • Nishikawa, S.I.1    Nishikawa, S.2    Hirashima, M.3    Matsuyoshi, N.4    Kodama, H.5
  • 74
    • 0034045599 scopus 로고    scopus 로고
    • A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1
    • Robertson SM, Kennedy M, Shannon JM, Keller G. A transitional stage in the commitment of mesoderm to hematopoiesis requiring the transcription factor SCL/tal-1. Development. 2000;127:2447-2459.
    • (2000) Development , vol.127 , pp. 2447-2459
    • Robertson, S.M.1    Kennedy, M.2    Shannon, J.M.3    Keller, G.4
  • 75
    • 18244403994 scopus 로고    scopus 로고
    • SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development
    • D'Souza SL, Elefanty AG, Keller G. SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development. Blood. 2005;105:3862-3870.
    • (2005) Blood , vol.105 , pp. 3862-3870
    • D'Souza, S.L.1    Elefanty, A.G.2    Keller, G.3
  • 76
    • 16844385559 scopus 로고    scopus 로고
    • The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells
    • Ng ES, Azzola L, Sourris K, Robb L, Stanley EG, Elefanty AG. The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells. Development. 2005;132:873-884.
    • (2005) Development , vol.132 , pp. 873-884
    • Ng, E.S.1    Azzola, L.2    Sourris, K.3    Robb, L.4    Stanley, E.G.5    Elefanty, A.G.6
  • 77
    • 0033594913 scopus 로고    scopus 로고
    • Conditional requirement for the Flk-1 receptor in the in vitro generation of early hematopoietic cells
    • U S A
    • Hidaka M, Stanford WL, Bernstein A. Conditional requirement for the Flk-1 receptor in the in vitro generation of early hematopoietic cells. Proc Natl Acad Sci U S A. 1999;96:7370-7375.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 7370-7375
    • Hidaka, M.1    Stanford, W.L.2    Bernstein, A.3
  • 78
    • 0141567655 scopus 로고    scopus 로고
    • A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis
    • Chan RJ, Johnson SA, Li Y, Yoder MC, Feng GS. A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis. Blood. 2003;102:2074-2080.
    • (2003) Blood , vol.102 , pp. 2074-2080
    • Chan, R.J.1    Johnson, S.A.2    Li, Y.3    Yoder, M.C.4    Feng, G.S.5
  • 79
    • 0037100461 scopus 로고    scopus 로고
    • Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro
    • Lacaud G, Gore L, Kennedy M, et al. Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro. Blood. 2002;100:458-466.
    • (2002) Blood , vol.100 , pp. 458-466
    • Lacaud, G.1    Gore, L.2    Kennedy, M.3
  • 80
    • 10344247125 scopus 로고    scopus 로고
    • Haemangioblast commitment is initiated in the primitive streak of the mouse embryo
    • Huber TL, Kouskoff V, Fehling HJ, Palis J, Keller G. Haemangioblast commitment is initiated in the primitive streak of the mouse embryo. Nature. 2004;432:625-630.
    • (2004) Nature , vol.432 , pp. 625-630
    • Huber, T.L.1    Kouskoff, V.2    Fehling, H.J.3    Palis, J.4    Keller, G.5
  • 81
    • 0029798732 scopus 로고    scopus 로고
    • A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro
    • Hole N, Graham GJ, Menzel U, Ansell JD. A limited temporal window for the derivation of multilineage repopulating hematopoietic progenitors during embryonal stem cell differentiation in vitro. Blood. 1996;88:1266-1276.
    • (1996) Blood , vol.88 , pp. 1266-1276
    • Hole, N.1    Graham, G.J.2    Menzel, U.3    Ansell, J.D.4
  • 82
    • 0027270776 scopus 로고
    • ES cells have only a limited lymphopoietic potential after adoptive transfer into mouse recipients
    • Muller AM, Dzierzak EA. ES cells have only a limited lymphopoietic potential after adoptive transfer into mouse recipients. Development. 1993;118:1343-1351.
    • (1993) Development , vol.118 , pp. 1343-1351
    • Muller, A.M.1    Dzierzak, E.A.2
  • 83
    • 1842782825 scopus 로고    scopus 로고
    • Embryonic stem cells as an alternate marrow donor source: Engraftment without graft-versus-host disease
    • Burt RK, Verda L, Kim DA, Oyama Y, Luo K, Link C. Embryonic stem cells as an alternate marrow donor source: engraftment without graft-versus-host disease. J Exp Med. 2004;199:895-904.
    • (2004) J Exp Med , vol.199 , pp. 895-904
    • Burt, R.K.1    Verda, L.2    Kim, D.A.3    Oyama, Y.4    Luo, K.5    Link, C.6
  • 84
    • 18844396119 scopus 로고    scopus 로고
    • Embryonic stem cell differentiation: Emergence of a new era in biology and medicine
    • Keller G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev. 2005;19:1129-1155.
    • (2005) Genes Dev , vol.19 , pp. 1129-1155
    • Keller, G.1
  • 85
    • 24044554221 scopus 로고    scopus 로고
    • Patterning definitive hematopoietic stem cells from embryonic stem cells
    • Lengerke C, Daley GQ. Patterning definitive hematopoietic stem cells from embryonic stem cells. Exp Hematol. 2005;33:971-979.
    • (2005) Exp Hematol. , vol.33 , pp. 971-979
    • Lengerke, C.1    Daley, G.Q.2
  • 86
    • 0029162605 scopus 로고
    • Murine embryonic yolk sac cells promote in vitro proliferation of bone marrow high proliferative potential colony-forming cells
    • Yoder MC, King B, Hiatt K, Williams DA. Murine embryonic yolk sac cells promote in vitro proliferation of bone marrow high proliferative potential colony-forming cells. Blood. 1995;86:1322-1330.
    • (1995) Blood , vol.86 , pp. 1322-1330
    • Yoder, M.C.1    King, B.2    Hiatt, K.3    Williams, D.A.4
  • 87
    • 0004887468 scopus 로고    scopus 로고
    • Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura
    • Cumano A, Dieterlen-Lievre F, Godin I. Lymphoid potential, probed before circulation in mouse, is restricted to caudal intraembryonic splanchnopleura. Cell. 1996;86:907-916.
    • (1996) Cell , vol.86 , pp. 907-916
    • Cumano, A.1    Dieterlen-Lievre, F.2    Godin, I.3
  • 88
    • 0027178567 scopus 로고
    • An early pre-liver intraembryonic source of CFU-S in the developing mouse
    • Medvinsky AL, Samoylina NL, Muller AM, Dzierzak EA. An early pre-liver intraembryonic source of CFU-S in the developing mouse. Nature. 1993;364:64-66.
    • (1993) Nature , vol.364 , pp. 64-66
    • Medvinsky, A.L.1    Samoylina, N.L.2    Muller, A.M.3    Dzierzak, E.A.4
  • 89
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell. 1996;86:897-906.
    • (1996) Cell , vol.86 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 90
    • 0034813102 scopus 로고    scopus 로고
    • Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution
    • Cumano A, Ferraz JC, Klaine M, Di Santo JP, Godin I. Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution. Immunity. 2001;15:477-485.
    • (2001) Immunity , vol.15 , pp. 477-485
    • Cumano, A.1    Ferraz, J.C.2    Klaine, M.3    Di Santo, J.P.4    Godin, I.5
  • 91
    • 0035203308 scopus 로고    scopus 로고
    • Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential
    • Perlingeiro RC, Kyba M, Daley GQ. Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential. Development. 2001;128:4597-4604.
    • (2001) Development , vol.128 , pp. 4597-4604
    • Perlingeiro, R.C.1    Kyba, M.2    Daley, G.Q.3
  • 92
    • 4544222705 scopus 로고    scopus 로고
    • Enforced activation of STAT5A facilitates the generation of embryonic stem-derived hematopoietic stem cells that contribute to hematopoiesis in vivo
    • Schuringa JJ, Wu K, Morrone G, Moore MA. Enforced activation of STAT5A facilitates the generation of embryonic stem-derived hematopoietic stem cells that contribute to hematopoiesis in vivo. Stem Cells. 2004;22:1191-1204.
    • (2004) Stem Cells , vol.22 , pp. 1191-1204
    • Schuringa, J.J.1    Wu, K.2    Morrone, G.3    Moore, M.A.4
  • 93
    • 0033080853 scopus 로고    scopus 로고
    • Hematopoietic progenitor cell abnormalities in Hoxc-8 null mutant mice
    • Shimamoto T, Tang Y, Naot Y, et al. Hematopoietic progenitor cell abnormalities in Hoxc-8 null mutant mice. J Exp Zool. 1999;283:186-193.
    • (1999) J Exp Zool , vol.283 , pp. 186-193
    • Shimamoto, T.1    Tang, Y.2    Naot, Y.3
  • 94
    • 0029954818 scopus 로고    scopus 로고
    • The role of HOX homeobox genes in normal and leukemic hematopoiesis
    • Lawrence HJ, Sauvageau G, Humphries RK, Largman C. The role of HOX homeobox genes in normal and leukemic hematopoiesis. Stem Cells. 1996;14:281-291.
    • (1996) Stem Cells , vol.14 , pp. 281-291
    • Lawrence, H.J.1    Sauvageau, G.2    Humphries, R.K.3    Largman, C.4
  • 95
    • 18744366334 scopus 로고    scopus 로고
    • Hox regulation of normal and leukemic hematopoietic stem cells
    • Abramovich C, Humphries RK. Hox regulation of normal and leukemic hematopoietic stem cells. Curr Opin Hematol. 2005;12:210-216.
    • (2005) Curr Opin Hematol , vol.12 , pp. 210-216
    • Abramovich, C.1    Humphries, R.K.2
  • 96
    • 0032722268 scopus 로고    scopus 로고
    • The role of homeobox genes in normal hematopoiesis and hematological malignancies
    • van Oostveen J, Bijl J, Raaphorst F, Walboomers J, Meijer C. The role of homeobox genes in normal hematopoiesis and hematological malignancies. Leukemia. 1999;13:1675-1690.
    • (1999) Leukemia , vol.13 , pp. 1675-1690
    • Van Oostveen, J.1    Bijl, J.2    Raaphorst, F.3    Walboomers, J.4    Meijer, C.5
  • 97
    • 0038246245 scopus 로고    scopus 로고
    • Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4
    • Bjornsson JM, Larsson N, Brun AC, et al. Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4. Mol Cell Biol. 2003;23:3872-3883.
    • (2003) Mol Cell Biol , vol.23 , pp. 3872-3883
    • Bjornsson, J.M.1    Larsson, N.2    Brun, A.C.3
  • 98
    • 9244257908 scopus 로고    scopus 로고
    • An Mll-dependent Hox program drives hematopoietic progenitor expansion
    • Ernst P, Mabon M, Davidson AJ, Zon LI, Korsmeyer SJ. An Mll-dependent Hox program drives hematopoietic progenitor expansion. Curr Biol. 2004;14:2063-2069.
    • (2004) Curr Biol , vol.14 , pp. 2063-2069
    • Ernst, P.1    Mabon, M.2    Davidson, A.J.3    Zon, L.I.4    Korsmeyer, S.J.5
  • 99
    • 0034892945 scopus 로고    scopus 로고
    • HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation
    • Antonchuk J, Sauvageau G, Humphries RK. HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation. Exp Hematol. 2001;29:1125-1134.
    • (2001) Exp Hematol , vol.29 , pp. 1125-1134
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 100
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 2002;109:39-45.
    • (2002) Cell , vol.109 , pp. 39-45
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 101
    • 0029091845 scopus 로고
    • Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
    • Sauvageau G, Thorsteinsdottir U, Eaves CJ, et al. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev. 1995;9:1753-1765.
    • (1995) Genes Dev , vol.9 , pp. 1753-1765
    • Sauvageau, G.1    Thorsteinsdottir, U.2    Eaves, C.J.3
  • 102
    • 0036682496 scopus 로고    scopus 로고
    • Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells
    • Buske C, Feuring-Buske M, Abramovich C, et al. Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood. 2002;100:862-868.
    • (2002) Blood , vol.100 , pp. 862-868
    • Buske, C.1    Feuring-Buske, M.2    Abramovich, C.3
  • 103
    • 0029947439 scopus 로고    scopus 로고
    • Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro
    • Helgason CD, Sauvageau G, Lawrence HJ, Largman C, Humphries RK. Overexpression of HOXB4 enhances the hematopoietic potential of embryonic stem cells differentiated in vitro. Blood. 1996;87:2740-2749.
    • (1996) Blood , vol.87 , pp. 2740-2749
    • Helgason, C.D.1    Sauvageau, G.2    Lawrence, H.J.3    Largman, C.4    Humphries, R.K.5
  • 104
    • 0037023544 scopus 로고    scopus 로고
    • HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors
    • Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell. 2002;109:29-37.
    • (2002) Cell , vol.109 , pp. 29-37
    • Kyba, M.1    Perlingeiro, R.C.2    Daley, G.Q.3
  • 105
    • 24744440551 scopus 로고    scopus 로고
    • HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells
    • U S A
    • Pilat S, Carotta S, Schiedlmeier B, et al. HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci U S A. 2005;102:12101-12106.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 12101-12106
    • Pilat, S.1    Carotta, S.2    Schiedlmeier, B.3
  • 106
    • 4944252717 scopus 로고    scopus 로고
    • Molecular interactions involved in HOXB4-induced activation of HSC self-renewal
    • Beslu N, Krosl J, Laurin M, Mayotte N, Humphries KR, Sauvageau G. Molecular interactions involved in HOXB4-induced activation of HSC self-renewal. Blood. 2004;104:2307-2314.
    • (2004) Blood , vol.104 , pp. 2307-2314
    • Beslu, N.1    Krosl, J.2    Laurin, M.3    Mayotte, N.4    Humphries, K.R.5    Sauvageau, G.6
  • 107
    • 18444411370 scopus 로고    scopus 로고
    • Activation of stem-cell specific genes by HOXA9 and HOXA10 homeodomain proteins in CD34+ human cord blood cells
    • Ferrell CM, Dorsam ST, Ohta H, et al. Activation of stem-cell specific genes by HOXA9 and HOXA10 homeodomain proteins in CD34+ human cord blood cells. Stem Cells. 2005;23:644-655.
    • (2005) Stem Cells , vol.23 , pp. 644-655
    • Ferrell, C.M.1    Dorsam, S.T.2    Ohta, H.3
  • 108
    • 0037082481 scopus 로고    scopus 로고
    • Cultivation of aorta-gonad-mesonephros-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances engraftment to the bone marrow
    • Takeuchi M, Sekiguchi T, Hara T, Kinoshita T, Miyajima A. Cultivation of aorta-gonad-mesonephros-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances engraftment to the bone marrow. Blood. 2002;99:1190-1196.
    • (2002) Blood , vol.99 , pp. 1190-1196
    • Takeuchi, M.1    Sekiguchi, T.2    Hara, T.3    Kinoshita, T.4    Miyajima, A.5
  • 109
    • 0031951550 scopus 로고    scopus 로고
    • In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aorta-gonad-mesonephros region
    • Mukouyama Y, Hara T, Xu M, et al. In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aorta-gonad- mesonephros region. Immunity. 1998;8:105-114.
    • (1998) Immunity , vol.8 , pp. 105-114
    • Mukouyama, Y.1    Hara, T.2    Xu, M.3
  • 110
    • 0037082497 scopus 로고    scopus 로고
    • Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity
    • Oostendorp RA, Harvey KN, Kusadasi N, et al. Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity. Blood. 2002;99:1183-1189.
    • (2002) Blood , vol.99 , pp. 1183-1189
    • Oostendorp, R.A.1    Harvey, K.N.2    Kusadasi, N.3
  • 111
    • 0036739779 scopus 로고    scopus 로고
    • Stromal cells from murine embryonic aorta-gonad-mesonephros region, liver and gut mesentery expand human umbilical cord blood-derived CAFC(week6) in extended long-term cultures
    • Kusadasi N, Oostendorp RA, Koevoet WJ, Dzierzak EA, Ploemacher RE. Stromal cells from murine embryonic aorta-gonad-mesonephros region, liver and gut mesentery expand human umbilical cord blood-derived CAFC(week6) in extended long-term cultures. Leukemia. 2002;16:1782-1790.
    • (2002) Leukemia , vol.16 , pp. 1782-1790
    • Kusadasi, N.1    Oostendorp, R.A.2    Koevoet, W.J.3    Dzierzak, E.A.4    Ploemacher, R.E.5
  • 112
    • 0035412395 scopus 로고    scopus 로고
    • Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells
    • Matsuoka S, Tsuji K, Hisakawa H, et al. Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells. Blood. 2001;98:6-12.
    • (2001) Blood , vol.98 , pp. 6-12
    • Matsuoka, S.1    Tsuji, K.2    Hisakawa, H.3
  • 113
    • 20344370721 scopus 로고    scopus 로고
    • Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures
    • Oostendorp RA, Robin C, Steinhoff C, et al. Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures. Stem Cells. 2005;23:842-851.
    • (2005) Stem Cells , vol.23 , pp. 842-851
    • Oostendorp, R.A.1    Robin, C.2    Steinhoff, C.3
  • 114
    • 0030029385 scopus 로고    scopus 로고
    • In vitro development of primitive and definitive erythrocytes from different precursors
    • Nakano T, Kodama H, Honjo T. In vitro development of primitive and definitive erythrocytes from different precursors. Science. 1996;272:722-724.
    • (1996) Science , vol.272 , pp. 722-724
    • Nakano, T.1    Kodama, H.2    Honjo, T.3
  • 115
    • 0344394521 scopus 로고    scopus 로고
    • Production of functional platelets by differentiated embryonic stem (ES) cells in vitro
    • Fujimoto TT, Kohata S, Suzuki H, Miyazaki H, Fujimura K. Production of functional platelets by differentiated embryonic stem (ES) cells in vitro. Blood. 2003;102:4044-4051.
    • (2003) Blood , vol.102 , pp. 4044-4051
    • Fujimoto, T.T.1    Kohata, S.2    Suzuki, H.3    Miyazaki, H.4    Fujimura, K.5
  • 117
    • 0346220084 scopus 로고    scopus 로고
    • Development and analysis of megakaryocytes from murine embryonic stem cells
    • Eto K, Leavitt AL, Nakano T, Shattil SJ. Development and analysis of megakaryocytes from murine embryonic stem cells. Methods Enzymol. 2003;365:142-158.
    • (2003) Methods Enzymol , vol.365 , pp. 142-158
    • Eto, K.1    Leavitt, A.L.2    Nakano, T.3    Shattil, S.J.4
  • 118
    • 0036790996 scopus 로고    scopus 로고
    • Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling
    • U S A
    • Eto K, Murphy R, Kerrigan SW, et al. Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling. Proc Natl Acad Sci U S A. 2002;99:12819-12824.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 12819-12824
    • Eto, K.1    Murphy, R.2    Kerrigan, S.W.3
  • 119
    • 0034141810 scopus 로고    scopus 로고
    • Characterization of hematopoietic lineage-specific gene expression by ES cell in vitro differentiation induction system
    • Era T, Takagi T, Takahashi T, Bories JC, Nakano T. Characterization of hematopoietic lineage-specific gene expression by ES cell in vitro differentiation induction system. Blood. 2000;95:870-878.
    • (2000) Blood , vol.95 , pp. 870-878
    • Era, T.1    Takagi, T.2    Takahashi, T.3    Bories, J.C.4    Nakano, T.5
  • 120
    • 4444343392 scopus 로고    scopus 로고
    • Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells
    • Carotta S, Pilat S, Mairhofer A, et al. Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells. Blood. 2004;104:1873-1880.
    • (2004) Blood , vol.104 , pp. 1873-1880
    • Carotta, S.1    Pilat, S.2    Mairhofer, A.3
  • 121
    • 0005432290 scopus 로고    scopus 로고
    • Mast cells derived from embryonic stem cells: A model system for studying the effects of genetic manipulations on mast cell development, phenotype, and function in vitro and in vivo
    • Tsai M, Tam SY, Wedemeyer J, Galli SJ. Mast cells derived from embryonic stem cells: a model system for studying the effects of genetic manipulations on mast cell development, phenotype, and function in vitro and in vivo. Int J Hematol. 2002;75:345-349.
    • (2002) Int J Hematol , vol.75 , pp. 345-349
    • Tsai, M.1    Tam, S.Y.2    Wedemeyer, J.3    Galli, S.J.4
  • 122
    • 0034675925 scopus 로고    scopus 로고
    • MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells
    • Garrington TP, Ishizuka T, Papst PJ, et al. MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells. EMBO J. 2000;19:5387-5395.
    • (2000) EMBO J , vol.19 , pp. 5387-5395
    • Garrington, T.P.1    Ishizuka, T.2    Papst, P.J.3
  • 123
    • 4744356098 scopus 로고    scopus 로고
    • Gene expression profiling shows that macrophages derived from mouse embryonic stem cells is an improved in vitro model for studies of vascular disease
    • Lindmark H, Rosengren B, Hurt-Camejo E, Bruder CE. Gene expression profiling shows that macrophages derived from mouse embryonic stem cells is an improved in vitro model for studies of vascular disease. Exp Cell Res. 2004;300:335-344.
    • (2004) Exp Cell Res , vol.300 , pp. 335-344
    • Lindmark, H.1    Rosengren, B.2    Hurt-Camejo, E.3    Bruder, C.E.4
  • 124
    • 0031688027 scopus 로고    scopus 로고
    • In vitro-differentiated embryonic stem cell macrophages: A model system for studying atherosclerosis-associated macrophage functions
    • Moore KJ, Fabunmi RP, Andersson LP, Freeman MW. In vitro-differentiated embryonic stem cell macrophages: a model system for studying atherosclerosis-associated macrophage functions. Arterioscler Thromb Vasc Biol. 1998;18:1647-1654.
    • (1998) Arterioscler Thromb Vasc Biol , vol.18 , pp. 1647-1654
    • Moore, K.J.1    Fabunmi, R.P.2    Andersson, L.P.3    Freeman, M.W.4
  • 125
    • 10144252434 scopus 로고    scopus 로고
    • Targeted disruption of guanosine diphosphate-dissociation inhibitor for Rho-related proteins, GDID4: Normal hematopoietic differentiation but subtle defect in superoxide production by macrophages derived from in vitro embryonal stem cell differentiation
    • Guillemot JC, Kruskal BA, Adra CN, et al. Targeted disruption of guanosine diphosphate-dissociation inhibitor for Rho-related proteins, GDID4: normal hematopoietic differentiation but subtle defect in superoxide production by macrophages derived from in vitro embryonal stem cell differentiation. Blood. 1996;88:2722-2731.
    • (1996) Blood , vol.88 , pp. 2722-2731
    • Guillemot, J.C.1    Kruskal, B.A.2    Adra, C.N.3
  • 126
    • 0042442273 scopus 로고    scopus 로고
    • In vitro generation of T lymphocytes from embryonic stem cell-derived prehematopoietic progenitors
    • de Pooter RF, Cho SK, Carlyle JR, Zuniga-Pflucker JC. In vitro generation of T lymphocytes from embryonic stem cell-derived prehematopoietic progenitors. Blood. 2003;102:1649-1653.
    • (2003) Blood , vol.102 , pp. 1649-1653
    • De Pooter, R.F.1    Cho, S.K.2    Carlyle, J.R.3    Zuniga-Pflucker, J.C.4
  • 127
    • 3042627641 scopus 로고    scopus 로고
    • Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro
    • Schmitt TM, de Pooter RF, Gronski MA, Cho SK, Ohashi PS, Zuniga-Pflucker JC. Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro. Nat Immunol. 2004;5:410-417.
    • (2004) Nat Immunol , vol.5 , pp. 410-417
    • Schmitt, T.M.1    De Pooter, R.F.2    Gronski, M.A.3    Cho, S.K.4    Ohashi, P.S.5    Zuniga-Pflucker, J.C.6
  • 129
    • 0346850639 scopus 로고    scopus 로고
    • Development of lymphoid lineages from embryonic stem cells in vitro
    • Cho SK, Zuniga-Pflucker JC. Development of lymphoid lineages from embryonic stem cells in vitro. Methods Enzymol. 2003;365:158-169.
    • (2003) Methods Enzymol , vol.365 , pp. 158-169
    • Cho, S.K.1    Zuniga-Pflucker, J.C.2
  • 130
    • 1642293963 scopus 로고    scopus 로고
    • Development and functional analysis of eosinophils from murine embryonic stem cells
    • Hamaguchi-Tsuru E, Nobumoto A, Hirose N, et al. Development and functional analysis of eosinophils from murine embryonic stem cells. Br J Haematol. 2004;124:819-827.
    • (2004) Br J Haematol , vol.124 , pp. 819-827
    • Hamaguchi-Tsuru, E.1    Nobumoto, A.2    Hirose, N.3
  • 131
    • 1642500383 scopus 로고    scopus 로고
    • The in vitro production and characterization of neutrophils from embryonic stem cells
    • Lieber JG, Webb S, Suratt BT, et al. The in vitro production and characterization of neutrophils from embryonic stem cells. Blood. 2004;103:852-859.
    • (2004) Blood , vol.103 , pp. 852-859
    • Lieber, J.G.1    Webb, S.2    Suratt, B.T.3
  • 132
    • 0347481206 scopus 로고    scopus 로고
    • The in vitro differentiation of mouse embryonic stem cells into neutrophils
    • Lieber JG, Keller GM, Worthen GS. The in vitro differentiation of mouse embryonic stem cells into neutrophils. Methods Enzymol. 2003;365:129-142.
    • (2003) Methods Enzymol , vol.365 , pp. 129-142
    • Lieber, J.G.1    Keller, G.M.2    Worthen, G.S.3
  • 133
    • 0038204238 scopus 로고    scopus 로고
    • Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells
    • Senju S, Hirata S, Matsuyoshi H, et al. Generation and genetic modification of dendritic cells derived from mouse embryonic stem cells. Blood. 2003;101:3501-3508.
    • (2003) Blood , vol.101 , pp. 3501-3508
    • Senju, S.1    Hirata, S.2    Matsuyoshi, H.3
  • 134
    • 0034735918 scopus 로고    scopus 로고
    • Directed differentiation of dendritic cells from mouse embryonic stem cells
    • Fairchild PJ, Brook FA, Gardner RL, et al. Directed differentiation of dendritic cells from mouse embryonic stem cells. Curr Biol. 2000;10:1515-1518.
    • (2000) Curr Biol , vol.10 , pp. 1515-1518
    • Fairchild, P.J.1    Brook, F.A.2    Gardner, R.L.3
  • 135
    • 0041495832 scopus 로고    scopus 로고
    • Probing dendritic cell function by guiding the differentiation of embryonic stem cells
    • Fairchild PJ, Nolan KF, Waldmann H. Probing dendritic cell function by guiding the differentiation of embryonic stem cells. Methods Enzymol. 2003;365:169-186.
    • (2003) Methods Enzymol , vol.365 , pp. 169-186
    • Fairchild, P.J.1    Nolan, K.F.2    Waldmann, H.3
  • 136
    • 0037093979 scopus 로고    scopus 로고
    • Orderly and nonstochastic acquisition of CD94/NKG2 receptors by developing NK cells derived from embryonic stem cells in vitro
    • Lian RH, Maeda M, Lohwasser S, et al. Orderly and nonstochastic acquisition of CD94/NKG2 receptors by developing NK cells derived from embryonic stem cells in vitro. J Immunol. 2002;168:4980-4987.
    • (2002) J Immunol , vol.168 , pp. 4980-4987
    • Lian, R.H.1    Maeda, M.2    Lohwasser, S.3
  • 137
    • 0030736411 scopus 로고    scopus 로고
    • Development of osteoclasts from embryonic stem cells through a pathway that is c-fms but not c-kit dependent
    • Yamane T, Kunisada T, Yamazaki H, Era T, Nakano T, Hayashi SI. Development of osteoclasts from embryonic stem cells through a pathway that is c-fms but not c-kit dependent. Blood. 1997;90:3516-3523.
    • (1997) Blood , vol.90 , pp. 3516-3523
    • Yamane, T.1    Kunisada, T.2    Yamazaki, H.3    Era, T.4    Nakano, T.5    Hayashi, S.I.6
  • 138
    • 0036134337 scopus 로고    scopus 로고
    • Embryonic stem cells as a model for studying osteoclast lineage development
    • Yamane T, Kunisada T, Hayashi S. Embryonic stem cells as a model for studying osteoclast lineage development. Methods Mol Biol. 2002;185:97-106.
    • (2002) Methods Mol Biol , vol.185 , pp. 97-106
    • Yamane, T.1    Kunisada, T.2    Hayashi, S.3
  • 140
    • 0142196780 scopus 로고    scopus 로고
    • Discrete types of osteoclast precursors can be generated from embryonic stem cells
    • Okuyama H, Tsuneto M, Yamane T, Yamazaki H, Hayashi S. Discrete types of osteoclast precursors can be generated from embryonic stem cells. Stem Cells. 2003;21:670-680.
    • (2003) Stem Cells , vol.21 , pp. 670-680
    • Okuyama, H.1    Tsuneto, M.2    Yamane, T.3    Yamazaki, H.4    Hayashi, S.5
  • 141
    • 0034811713 scopus 로고    scopus 로고
    • Temporal and spatial localization of osteoclasts in colonies from embryonic stem cells
    • Hemmi H, Okuyama H, Yamane T, et al. Temporal and spatial localization of osteoclasts in colonies from embryonic stem cells. Biochem Biophys Res Commun. 2001;280:526-534.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 526-534
    • Hemmi, H.1    Okuyama, H.2    Yamane, T.3
  • 142
    • 0028233760 scopus 로고
    • Novel insights into erythroid development revealed through in vitro differentiation of GATA-1- Embryonic stem cells
    • Weiss MJ, Keller G, Orkin SH. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1- embryonic stem cells. Genes Dev. 1994;8:1184-1197.
    • (1994) Genes Dev , vol.8 , pp. 1184-1197
    • Weiss, M.J.1    Keller, G.2    Orkin, S.H.3
  • 143
    • 0028800317 scopus 로고
    • Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis
    • U S A
    • Weiss MJ, Orkin SH. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc Natl Acad Sci U S A. 1995;92:9623-9627.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 9623-9627
    • Weiss, M.J.1    Orkin, S.H.2
  • 144
    • 0031024994 scopus 로고    scopus 로고
    • Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line
    • Weiss MJ, Yu C, Orkin SH. Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line. Mol Cell Biol. 1997;17:1642-1651.
    • (1997) Mol Cell Biol , vol.17 , pp. 1642-1651
    • Weiss, M.J.1    Yu, C.2    Orkin, S.H.3
  • 145
    • 0033168769 scopus 로고    scopus 로고
    • GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression
    • Gregory T, Yu C, Ma A, Orkin SH, Blobel GA, Weiss MJ. GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression. Blood. 1999;94:87-96.
    • (1999) Blood , vol.94 , pp. 87-96
    • Gregory, T.1    Yu, C.2    Ma, A.3    Orkin, S.H.4    Blobel, G.A.5    Weiss, M.J.6
  • 146
    • 0037071860 scopus 로고    scopus 로고
    • An abundant erythroid protein that stabilizes free alpha hemoglobin
    • Kihm AJ, Kong Y, Hong W, et al. An abundant erythroid protein that stabilizes free alpha hemoglobin. Nature. 2002;417:758-763.
    • (2002) Nature , vol.417 , pp. 758-763
    • Kihm, A.J.1    Kong, Y.2    Hong, W.3
  • 147
    • 0034213588 scopus 로고    scopus 로고
    • ABC-me, a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation
    • Shirihai OS, Gregory T, Yu C, Orkin SH, Weiss MJ. ABC-me, a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. EMBO J. 2000;19:2492-2502.
    • (2000) EMBO J , vol.19 , pp. 2492-2502
    • Shirihai, O.S.1    Gregory, T.2    Yu, C.3    Orkin, S.H.4    Weiss, M.J.5
  • 148
    • 0038111018 scopus 로고    scopus 로고
    • GATA-1-mediated proliferation arrest during erythroid maturation
    • Rylski M, Welch JJ, Chen Y-Y, et al. GATA-1-mediated proliferation arrest during erythroid maturation. Mol Cell Biol. 2003;23:5031-5042.
    • (2003) Mol Cell Biol , vol.23 , pp. 5031-5042
    • Rylski, M.1    Welch, J.J.2    Chen, Y.-Y.3
  • 149
    • 13244272059 scopus 로고    scopus 로고
    • Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1
    • Vakoc CR, Letting DL, Gheldof N, et al. Proximity among distant regulatory elements at the beta-globin locus requires GATA-1 and FOG-1. Mol Cell. 2005;17:453-462.
    • (2005) Mol Cell , vol.17 , pp. 453-462
    • Vakoc, C.R.1    Letting, D.L.2    Gheldof, N.3
  • 150
    • 0037015075 scopus 로고    scopus 로고
    • Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain
    • U S A
    • Johnson KD, Grass JA, Boyer ME, et al. Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain. Proc Natl Acad Sci U S A. 2002;99:11760-11765.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 11760-11765
    • Johnson, K.D.1    Grass, J.A.2    Boyer, M.E.3
  • 151
    • 0033568426 scopus 로고    scopus 로고
    • The presence of novel amino acids in the cytoplasmic domain of stem cell factor results in hematopoietic defects in Steel(17H) mice
    • Kapur R, Cooper R, Xiao X, Weiss MJ, Donovan P, Williams DA. The presence of novel amino acids in the cytoplasmic domain of stem cell factor results in hematopoietic defects in Steel(17H) mice. Blood. 1999;94:1915-1925.
    • (1999) Blood , vol.94 , pp. 1915-1925
    • Kapur, R.1    Cooper, R.2    Xiao, X.3    Weiss, M.J.4    Donovan, P.5    Williams, D.A.6
  • 152
    • 85047690518 scopus 로고    scopus 로고
    • Loss of alphahemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia
    • Kong Y, Zhou S, Kihm AJ, et al. Loss of alphahemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia. J Clin Invest. 2004;114:1457-1466.
    • (2004) J Clin Invest , vol.114 , pp. 1457-1466
    • Kong, Y.1    Zhou, S.2    Kihm, A.J.3
  • 153
    • 22544452677 scopus 로고    scopus 로고
    • Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation
    • Munugalavadla V, Dore LC, Tan BL, et al. Repression of c-kit and its downstream substrates by GATA-1 inhibits cell proliferation during erythroid maturation. Mol Cell Biol. 2005;25:6747-6759.
    • (2005) Mol Cell Biol , vol.25 , pp. 6747-6759
    • Munugalavadla, V.1    Dore, L.C.2    Tan, B.L.3
  • 154
    • 30444440180 scopus 로고    scopus 로고
    • Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells
    • Prepublished on September 20, 2005, as DOI 10.1182/blood-2005-04-1385
    • Zheng J, Kitajima K, Sakai E, et al. Differential effects of GATA-1 on proliferation and differentiation of erythroid lineage cells. Blood. Prepublished on September 20, 2005, as DOI 10.1182/blood-2005-04-1385.
    • Blood
    • Zheng, J.1    Kitajima, K.2    Sakai, E.3
  • 155
    • 0033566296 scopus 로고    scopus 로고
    • The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro
    • von Lindern M, Zauner W, Mellitzer G, et al. The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro. Blood. 1999;94:550-559.
    • (1999) Blood , vol.94 , pp. 550-559
    • Von Lindern, M.1    Zauner, W.2    Mellitzer, G.3
  • 156
    • 0032983186 scopus 로고    scopus 로고
    • A novel way to induce erythroid progenitor self renewal: Cooperation of c-Kit with the erythropoietin receptor
    • Wessely O, Bauer A, Quang CT, et al. A novel way to induce erythroid progenitor self renewal: cooperation of c-Kit with the erythropoietin receptor. Biol Chem. 1999;380:187-202.
    • (1999) Biol Chem , vol.380 , pp. 187-202
    • Wessely, O.1    Bauer, A.2    Quang, C.T.3
  • 157
    • 0031032760 scopus 로고    scopus 로고
    • The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors
    • Wessely O, Deiner EM, Beug H, von Lindern M. The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors. EMBO J. 1997;16:267-280.
    • (1997) EMBO J , vol.16 , pp. 267-280
    • Wessely, O.1    Deiner, E.M.2    Beug, H.3    Von Lindern, M.4
  • 158
    • 0029006696 scopus 로고
    • Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
    • Shalaby F, Rossant J, Yamaguchi TP, et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature. 1995;376:62-66.
    • (1995) Nature , vol.376 , pp. 62-66
    • Shalaby, F.1    Rossant, J.2    Yamaguchi, T.P.3
  • 159
    • 30144433626 scopus 로고    scopus 로고
    • An early block to erythro-megakaryocytic development conferred by loss of transcription factor GATA-1
    • Stachura DL, Chou ST, Weiss MJ. An early block to erythro-megakaryocytic development conferred by loss of transcription factor GATA-1. Blood. 2006;107:87-97.
    • (2006) Blood , vol.107 , pp. 87-97
    • Stachura, D.L.1    Chou, S.T.2    Weiss, M.J.3
  • 160
    • 11144242549 scopus 로고    scopus 로고
    • Origins of leukaemia in children with Down syndrome
    • Hitzler JK, Zipursky A. Origins of leukaemia in children with Down syndrome. Nat Rev Cancer. 2005;5:11-20.
    • (2005) Nat Rev Cancer , vol.5 , pp. 11-20
    • Hitzler, J.K.1    Zipursky, A.2
  • 161
    • 0034254985 scopus 로고    scopus 로고
    • In vivo immunological function of mast cells derived from embryonic stem cells: An approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo
    • U S A
    • Tsai M, Wedemeyer J, Ganiatsas S, Tam SY, Zon LI, Galli SJ. In vivo immunological function of mast cells derived from embryonic stem cells: an approach for the rapid analysis of even embryonic lethal mutations in adult mice in vivo. Proc Natl Acad Sci U S A. 2000;97:9186-9190.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 9186-9190
    • Tsai, M.1    Wedemeyer, J.2    Ganiatsas, S.3    Tam, S.Y.4    Zon, L.I.5    Galli, S.J.6
  • 162
    • 18744366041 scopus 로고    scopus 로고
    • Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
    • Takayanagi H, Kim S, Koga T, et al. Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell. 2002;3:889-901.
    • (2002) Dev Cell , vol.3 , pp. 889-901
    • Takayanagi, H.1    Kim, S.2    Koga, T.3
  • 163
    • 12144270059 scopus 로고    scopus 로고
    • Enforced expression of PU.1 rescues osteoclastogenesis from embryonic stem cells lacking Tal-1
    • Tsuneto M, Tominaga A, Yamazaki H, Yoshino M, Orkin SH, Hayashi S. Enforced expression of PU.1 rescues osteoclastogenesis from embryonic stem cells lacking Tal-1. Stem Cells. 2005;23:134-143.
    • (2005) Stem Cells , vol.23 , pp. 134-143
    • Tsuneto, M.1    Tominaga, A.2    Yamazaki, H.3    Yoshino, M.4    Orkin, S.H.5    Hayashi, S.6
  • 164
    • 0037186519 scopus 로고    scopus 로고
    • Monoclonal mice generated by nuclear transfer from mature B and T donor cells
    • Hochedlinger K, Jaenisch R. Monoclonal mice generated by nuclear transfer from mature B and T donor cells. Nature. 2002;415:1035-1038.
    • (2002) Nature , vol.415 , pp. 1035-1038
    • Hochedlinger, K.1    Jaenisch, R.2
  • 165
    • 20544451854 scopus 로고    scopus 로고
    • Patient-specific embryonic stem cells derived from human SCNT blastocysts
    • Hwang WS, Roh SI, Lee BC, et al. Patient-specific embryonic stem cells derived from human SCNT blastocysts. Science. 2005;308:1777-1783.
    • (2005) Science , vol.308 , pp. 1777-1783
    • Hwang, W.S.1    Roh, S.I.2    Lee, B.C.3
  • 166
    • 12144286557 scopus 로고    scopus 로고
    • Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst
    • Hwang WS, Ryu YJ, Park JH, et al. Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. Science. 2004;303:1669-1674.
    • (2004) Science , vol.303 , pp. 1669-1674
    • Hwang, W.S.1    Ryu, Y.J.2    Park, J.H.3
  • 167
    • 11244285402 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived CD34+ cells: Efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential
    • Vodyanik MA, Bork JA, Thomson JA, Slukvin I. Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood. 2005;105:617-626.
    • (2005) Blood , vol.105 , pp. 617-626
    • Vodyanik, M.A.1    Bork, J.A.2    Thomson, J.A.3    Slukvin, I.4
  • 169
    • 6944229647 scopus 로고    scopus 로고
    • Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells
    • Tian X, Morris JK, Linehan JL, Kaufman DS. Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells. Exp Hematol. 2004;32:1000-1009.
    • (2004) Exp Hematol , vol.32 , pp. 1000-1009
    • Tian, X.1    Morris, J.K.2    Linehan, J.L.3    Kaufman, D.S.4
  • 170
    • 23044512574 scopus 로고    scopus 로고
    • Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development
    • Zambidis ET, Peault B, Park TS, Bunz F, Civin CI. Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development. Blood. 2005;106:860-870.
    • (2005) Blood , vol.106 , pp. 860-870
    • Zambidis, E.T.1    Peault, B.2    Park, T.S.3    Bunz, F.4    Civin, C.I.5
  • 171
    • 3142776112 scopus 로고    scopus 로고
    • Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties
    • Wang L, Li L, Shojaei F, et al. Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity. 2004;21:31-41.
    • (2004) Immunity , vol.21 , pp. 31-41
    • Wang, L.1    Li, L.2    Shojaei, F.3
  • 172
    • 0034983625 scopus 로고    scopus 로고
    • Multilineage differentiation from human embryonic stem cell lines
    • Odorico JS, Kaufman DS, Thomson JA. Multilineage differentiation from human embryonic stem cell lines. Stem Cells. 2001;19:193-204.
    • (2001) Stem Cells , vol.19 , pp. 193-204
    • Odorico, J.S.1    Kaufman, D.S.2    Thomson, J.A.3
  • 173
    • 19344361972 scopus 로고    scopus 로고
    • Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression
    • Wang L, Menendez P, Shojaei F, et al. Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med. 2005;201:1603-1614.
    • (2005) J Exp Med , vol.201 , pp. 1603-1614
    • Wang, L.1    Menendez, P.2    Shojaei, F.3
  • 174
    • 0030946401 scopus 로고    scopus 로고
    • Engraftment of embryonic hematopoietic cells in conditioned newborn recipients
    • Yoder MC, Hiatt K. Engraftment of embryonic hematopoietic cells in conditioned newborn recipients. Blood. 1997;89:2176-2183.
    • (1997) Blood , vol.89 , pp. 2176-2183
    • Yoder, M.C.1    Hiatt, K.2
  • 175
    • 2542418035 scopus 로고    scopus 로고
    • CD34+CD38- Hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern
    • Lu SJ, Li F, Vida L, Honig GR. CD34+CD38- hematopoietic precursors derived from human embryonic stem cells exhibit an embryonic gene expression pattern. Blood. 2004;103:4134-4141.
    • (2004) Blood , vol.103 , pp. 4134-4141
    • Lu, S.J.1    Li, F.2    Vida, L.3    Honig, G.R.4
  • 176
    • 5444256802 scopus 로고    scopus 로고
    • Genetic programs regulating HSC specification, maintenance and expansion
    • Lessard J, Faubert A, Sauvageau G. Genetic programs regulating HSC specification, maintenance and expansion. Oncogene. 2004;23:7199-7209.
    • (2004) Oncogene , vol.23 , pp. 7199-7209
    • Lessard, J.1    Faubert, A.2    Sauvageau, G.3
  • 177
    • 0141483056 scopus 로고    scopus 로고
    • Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5
    • U S A
    • Kyba M, Perlingeiro RC, Hoover RR, Lu CW, Pierce J, Daley GQ. Enhanced hematopoietic differentiation of embryonic stem cells conditionally expressing Stat5. Proc Natl Acad Sci U S A. 2003;100(suppl 1):11904-11910.
    • (2003) Proc Natl Acad Sci , vol.100 , Issue.1 SUPPL. , pp. 11904-11910
    • Kyba, M.1    Perlingeiro, R.C.2    Hoover, R.R.3    Lu, C.W.4    Pierce, J.5    Daley, G.Q.6
  • 178
    • 23844452706 scopus 로고    scopus 로고
    • NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal
    • U S A
    • Zhu J, Zhang Y, Joe GJ, Pompetti R, Emerson SG. NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal. Proc Natl Acad Sci U S A. 2005;102:11728-11733.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 11728-11733
    • Zhu, J.1    Zhang, Y.2    Joe, G.J.3    Pompetti, R.4    Emerson, S.G.5
  • 179
    • 0344413639 scopus 로고    scopus 로고
    • In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
    • Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G. In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med. 2003;9:1428-1432.
    • (2003) Nat Med , vol.9 , pp. 1428-1432
    • Krosl, J.1    Austin, P.2    Beslu, N.3    Kroon, E.4    Humphries, R.K.5    Sauvageau, G.6
  • 182
    • 10744231807 scopus 로고    scopus 로고
    • Factor VIII ectopically expressed in platelets: Efficacy in hemophilia a treatment
    • Yarovoi HV, Kufrin D, Eslin DE, et al. Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment. Blood. 2003;102:4006-4013.
    • (2003) Blood , vol.102 , pp. 4006-4013
    • Yarovoi, H.V.1    Kufrin, D.2    Eslin, D.E.3
  • 183
    • 0041743223 scopus 로고    scopus 로고
    • Antithrombotic thrombocytes: Ectopic expression of urokinasetype plasminogen activator in platelets
    • Kufrin D, Eslin DE, Bdeir K, et al. Antithrombotic thrombocytes: ectopic expression of urokinasetype plasminogen activator in platelets. Blood. 2003;102:926-933.
    • (2003) Blood , vol.102 , pp. 926-933
    • Kufrin, D.1    Eslin, D.E.2    Bdeir, K.3
  • 184
    • 9744246012 scopus 로고    scopus 로고
    • Progress with nonhuman primate embryonic stem cells
    • Wolf DP, Kuo HC, Pau KY, Lester L. Progress with nonhuman primate embryonic stem cells. Biol Reprod. 2004;71:1766-1771.
    • (2004) Biol Reprod , vol.71 , pp. 1766-1771
    • Wolf, D.P.1    Kuo, H.C.2    Pau, K.Y.3    Lester, L.4
  • 185
    • 2342440756 scopus 로고    scopus 로고
    • Development of primitive and definitive hematopoiesis from nonhuman primate embryonic stem cells in vitro
    • Umeda K, Heike T, Yoshimoto M, et al. Development of primitive and definitive hematopoiesis from nonhuman primate embryonic stem cells in vitro. Development. 2004;131:1869-1879.
    • (2004) Development , vol.131 , pp. 1869-1879
    • Umeda, K.1    Heike, T.2    Yoshimoto, M.3
  • 186
    • 24044474697 scopus 로고    scopus 로고
    • Nonhuman primate embryonic stem cells as a preclinical model for hematopoietic and vascular repair
    • Hematti P, Obrtlikova P, Kaufman DS. Nonhuman primate embryonic stem cells as a preclinical model for hematopoietic and vascular repair. Exp Hematol. 2005;33:980-986.
    • (2005) Exp Hematol , vol.33 , pp. 980-986
    • Hematti, P.1    Obrtlikova, P.2    Kaufman, D.S.3
  • 187
    • 13544256600 scopus 로고    scopus 로고
    • Efficient and stable Sendai virus-mediated gene transfer into primate embryonic stem cells with pluripotency preserved
    • Sasaki K, Inoue M, Shibata H, et al. Efficient and stable Sendai virus-mediated gene transfer into primate embryonic stem cells with pluripotency preserved. Gene Ther. 2005;12:203-210.
    • (2005) Gene Ther , vol.12 , pp. 203-210
    • Sasaki, K.1    Inoue, M.2    Shibata, H.3
  • 188
    • 17144473689 scopus 로고    scopus 로고
    • Engraftment and tumor formation after allogeneic in utero transplantation of primate embryonic stem cells
    • Asano T, Ageyama N, Takeuchi K, et al. Engraftment and tumor formation after allogeneic in utero transplantation of primate embryonic stem cells. Transplantation. 2003;76:1061-1067.
    • (2003) Transplantation , vol.76 , pp. 1061-1067
    • Asano, T.1    Ageyama, N.2    Takeuchi, K.3


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