메뉴 건너뛰기




Volumn 104, Issue 8, 2004, Pages 2307-2314

Molecular interactions involved in HOXB4-induced activation of HSC self-renewal

Author keywords

[No Author keywords available]

Indexed keywords

HOX PROTEIN; HOXB4 PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

EID: 4944252717     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-04-1653     Document Type: Article
Times cited : (56)

References (58)
  • 1
    • 0030729371 scopus 로고    scopus 로고
    • Effects of HOX homeobox genes in blood cell differentiation
    • Magli MC, Largman C, Lawrence HJ. Effects of HOX homeobox genes in blood cell differentiation. J Cell Physiol. 1997;173:168-177.
    • (1997) J Cell Physiol , vol.173 , pp. 168-177
    • Magli, M.C.1    Largman, C.2    Lawrence, H.J.3
  • 2
    • 0034203281 scopus 로고    scopus 로고
    • Homeobox genes in leukemogenesis
    • Buske C, Humphries RK. Homeobox genes in leukemogenesis. Int J Hematol. 2000;71:301-308.
    • (2000) Int J Hematol , vol.71 , pp. 301-308
    • Buske, C.1    Humphries, R.K.2
  • 3
    • 0029091845 scopus 로고
    • Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
    • Sauvageau G, Thorsteinsdottir U, Eaves CJ, et al. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev. 1995;9:1753-1765.
    • (1995) Genes Dev , vol.9 , pp. 1753-1765
    • Sauvageau, G.1    Thorsteinsdottir, U.2    Eaves, C.J.3
  • 4
    • 0032857035 scopus 로고    scopus 로고
    • Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size
    • Thorsteinsdottir U, Sauvageau G, Humphries RK. Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size. Blood. 1999;94: 2605-2612.
    • (1999) Blood , vol.94 , pp. 2605-2612
    • Thorsteinsdottir, U.1    Sauvageau, G.2    Humphries, R.K.3
  • 5
    • 0034892945 scopus 로고    scopus 로고
    • HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation
    • Antonchuk J, Sauvageau G, Humphries RK. HOXB4 overexpression mediates very rapid stem cell regeneration and competitive hematopoietic repopulation. Exp Hematol. 2001;29:1125-1134.
    • (2001) Exp Hematol , vol.29 , pp. 1125-1134
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 6
    • 0037023528 scopus 로고    scopus 로고
    • HOXB4-induced expansion of adult hematopoietic stem cells ex vivo
    • Antonchuk J, Sauvageau G, Humphries RK. HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell. 2002;109:39-45.
    • (2002) Cell , vol.109 , pp. 39-45
    • Antonchuk, J.1    Sauvageau, G.2    Humphries, R.K.3
  • 7
    • 0344413639 scopus 로고    scopus 로고
    • In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
    • Krosl J, Austin P, Beslu N, et al. In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med. 2003;9:1428-1432.
    • (2003) Nat Med , vol.9 , pp. 1428-1432
    • Krosl, J.1    Austin, P.2    Beslu, N.3
  • 8
    • 0345708270 scopus 로고    scopus 로고
    • Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein
    • Amsellem S, Pflumio F, Bardinet D, et al. Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein. Nat Med. 2003;9:1423-1427.
    • (2003) Nat Med , vol.9 , pp. 1423-1427
    • Amsellem, S.1    Pflumio, F.2    Bardinet, D.3
  • 9
    • 0037370740 scopus 로고    scopus 로고
    • + cells, but impairs lymphomyeloid differentiation
    • + cells, but impairs lymphomyeloid differentiation. Blood. 2003;101:1759-1768.
    • (2003) Blood , vol.101 , pp. 1759-1768
    • Schiedlmeier, B.1    Klump, H.2    Will, E.3
  • 10
    • 0031149988 scopus 로고    scopus 로고
    • Drosophila Hox complex downstream targets and the function of homeotic genes
    • Graba Y, Aragnol D, Pradel J. Drosophila Hox complex downstream targets and the function of homeotic genes. Bioessays. 1997;19:379-388.
    • (1997) Bioessays , vol.19 , pp. 379-388
    • Graba, Y.1    Aragnol, D.2    Pradel, J.3
  • 11
    • 0029939199 scopus 로고    scopus 로고
    • Pbx modulation of Hox homeodomain amino-terminal arms establishes different DMA-binding specificities across the Hox locus
    • Chang CP, Brocchieri L, Shen WF, Largman C, Cleary ML. Pbx modulation of Hox homeodomain amino-terminal arms establishes different DMA-binding specificities across the Hox locus. Mol Cell Biol. 1996;16:1734-1745.
    • (1996) Mol Cell Biol , vol.16 , pp. 1734-1745
    • Chang, C.P.1    Brocchieri, L.2    Shen, W.F.3    Largman, C.4    Cleary, M.L.5
  • 12
    • 0029666297 scopus 로고    scopus 로고
    • Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3′ to a TAAT motif
    • Knoepfler PS, Lu Q, Kamps MP. Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3′ to a TAAT motif. Nucleic Acids Res. 1996;24:2288-2294.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2288-2294
    • Knoepfler, P.S.1    Lu, Q.2    Kamps, M.P.3
  • 13
    • 0029865897 scopus 로고    scopus 로고
    • Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA
    • Shen WF, Chang CP, Rozenfeld S, et al. Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA. Nucleic Acids Res. 1996;24:898-906.
    • (1996) Nucleic Acids Res , vol.24 , pp. 898-906
    • Shen, W.F.1    Chang, C.P.2    Rozenfeld, S.3
  • 14
    • 0031031879 scopus 로고    scopus 로고
    • The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis
    • Chang CP, de Vivo I, Cleary ML. The Hox cooperativity motif of the chimeric oncoprotein E2a-Pbx1 is necessary and sufficient for oncogenesis. Mol Cell Biol. 1997;17:81-88.
    • (1997) Mol Cell Biol , vol.17 , pp. 81-88
    • Chang, C.P.1    De Vivo, I.2    Cleary, M.L.3
  • 15
    • 0031003129 scopus 로고    scopus 로고
    • Positive cross-regulation and enhancer sharing: Two mechanisms for specifying overlapping Hox expression patterns
    • Gould A, Morrison A, Sproat G, White RA, Krumlauf R. Positive cross-regulation and enhancer sharing: two mechanisms for specifying overlapping Hox expression patterns. Genes Dev. 1997; 11:900-913.
    • (1997) Genes Dev , vol.11 , pp. 900-913
    • Gould, A.1    Morrison, A.2    Sproat, G.3    White, R.A.4    Krumlauf, R.5
  • 16
    • 0029055810 scopus 로고
    • Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
    • Popperl H, Bienz M, Studer M, et al. Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx. Cell. 1995;81:1031-1042.
    • (1995) Cell , vol.81 , pp. 1031-1042
    • Popperl, H.1    Bienz, M.2    Studer, M.3
  • 17
    • 0033767384 scopus 로고    scopus 로고
    • Cell signaling switches HOX-PBX complexes from repressers to activators of transcription mediated by histone deacetylases and histone acetyltransferases
    • Saleh M, Rambaldi I, Yang XJ, Featherstone MS. Cell signaling switches HOX-PBX complexes from repressers to activators of transcription mediated by histone deacetylases and histone acetyltransferases. Mol Cell Biol. 2000;20:8623-8633.
    • (2000) Mol Cell Biol , vol.20 , pp. 8623-8633
    • Saleh, M.1    Rambaldi, I.2    Yang, X.J.3    Featherstone, M.S.4
  • 18
    • 0030848853 scopus 로고    scopus 로고
    • AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins
    • Shen WF, Montgomery JC, Rozenfeld S, et al. AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol Cell Biol. 1997;17:6448-6458.
    • (1997) Mol Cell Biol , vol.17 , pp. 6448-6458
    • Shen, W.F.1    Montgomery, J.C.2    Rozenfeld, S.3
  • 19
    • 0032473422 scopus 로고    scopus 로고
    • The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity
    • Berthelsen J, Zappavigna V, Ferretti E, Mavilio F, Blasi F. The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity. EMBO J. 1998;17:1434-1445.
    • (1998) EMBO J , vol.17 , pp. 1434-1445
    • Berthelsen, J.1    Zappavigna, V.2    Ferretti, E.3    Mavilio, F.4    Blasi, F.5
  • 20
    • 0033036185 scopus 로고    scopus 로고
    • Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity
    • Jacobs Y, Schnabel CA, Cleary ML. Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity. Mol Cell Biol. 1999;19:5134-5142.
    • (1999) Mol Cell Biol , vol.19 , pp. 5134-5142
    • Jacobs, Y.1    Schnabel, C.A.2    Cleary, M.L.3
  • 21
    • 0031964860 scopus 로고    scopus 로고
    • Functional and regulatory interactions between Hox and extradenticle genes
    • Azpiazu N, Morata G. Functional and regulatory interactions between Hox and extradenticle genes. Genes Dev. 1998;12:261-273.
    • (1998) Genes Dev , vol.12 , pp. 261-273
    • Azpiazu, N.1    Morata, G.2
  • 22
    • 18344401779 scopus 로고    scopus 로고
    • In vivo mutagenesis of the HoxbS hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster
    • Medina-Martinez O, Ramirez-Solis R. In vivo mutagenesis of the HoxbS hexapeptide domain leads to dominant homeotic transformations that mimic the loss-of-function mutations in genes of the Hoxb cluster. Dev Biol. 2003;264:77-90.
    • (2003) Dev Biol , vol.264 , pp. 77-90
    • Medina-Martinez, O.1    Ramirez-Solis, R.2
  • 23
    • 0033968939 scopus 로고    scopus 로고
    • Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins
    • Ferretti E, Marshall H, Popperl H, et al. Segmental expression of Hoxb2 in r4 requires two separate sites that integrate cooperative interactions between Prep1, Pbx and Hox proteins. Development. 2000;127:155-166.
    • (2000) Development , vol.127 , pp. 155-166
    • Ferretti, E.1    Marshall, H.2    Popperl, H.3
  • 24
    • 0033404512 scopus 로고    scopus 로고
    • Regulation of Hox target genes by a DNA bound Homothorax/Hox/ Extradenticle complex
    • Ryoo HD, Matty T, Casares F, Affolter M, Mann RS. Regulation of Hox target genes by a DNA bound Homothorax/Hox/Extradenticle complex. Deyelopment. 1999;126:5137-5148.
    • (1999) Deyelopment , vol.126 , pp. 5137-5148
    • Ryoo, H.D.1    Matty, T.2    Casares, F.3    Affolter, M.4    Mann, R.S.5
  • 25
    • 0036337125 scopus 로고    scopus 로고
    • Hox repression of a target gene: Extradenticle-independent, additive action through multiple monomer binding sites
    • Galant R, Walsh CM, Carroll SB. Hox repression of a target gene: extradenticle-independent, additive action through multiple monomer binding sites. Development. 2002;129:3115-3126.
    • (2002) Development , vol.129 , pp. 3115-3126
    • Galant, R.1    Walsh, C.M.2    Carroll, S.B.3
  • 26
    • 0037991521 scopus 로고    scopus 로고
    • The hexapeptide and linker regions of the AbdA Hox protein regulate its activating and repressive functions
    • Merabet S, Kambris Z, Capovilla M, et al. The hexapeptide and linker regions of the AbdA Hox protein regulate its activating and repressive functions. Dev Cell. 2003;4:761-768.
    • (2003) Dev Cell , vol.4 , pp. 761-768
    • Merabet, S.1    Kambris, Z.2    Capovilla, M.3
  • 27
    • 0034598793 scopus 로고    scopus 로고
    • HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis
    • Schnabel CA, Jacobs Y, Cleary ML. HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis. Oncogene. 2000;19:608-616.
    • (2000) Oncogene , vol.19 , pp. 608-616
    • Schnabel, C.A.1    Jacobs, Y.2    Cleary, M.L.3
  • 28
    • 0034000574 scopus 로고    scopus 로고
    • Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression
    • Calvo KR, Sykes DB, Pasillas M, Kamps MP. Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression. Mol Cell Biol. 2000;20: 3274-3285.
    • (2000) Mol Cell Biol , vol.20 , pp. 3274-3285
    • Calvo, K.R.1    Sykes, D.B.2    Pasillas, M.3    Kamps, M.P.4
  • 29
    • 0035817740 scopus 로고    scopus 로고
    • HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation
    • Knoepfler PS, Sykes DB, Pasillas M, Kamps MP. HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation. Oncogene. 2001;20:5440-5448.
    • (2001) Oncogene , vol.20 , pp. 5440-5448
    • Knoepfler, P.S.1    Sykes, D.B.2    Pasillas, M.3    Kamps, M.P.4
  • 30
    • 0032126633 scopus 로고    scopus 로고
    • Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1 a but not Pbx1b
    • Kroon E, Krosl J, Thorsteinsdottir U, et al. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1 a but not Pbx1b. EMBO J. 1998;17:3714-3725.
    • (1998) EMBO J , vol.17 , pp. 3714-3725
    • Kroon, E.1    Krosl, J.2    Thorsteinsdottir, U.3
  • 31
  • 32
    • 0029671035 scopus 로고    scopus 로고
    • Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide
    • Copeland JW, Nasiadka A, Dietrich BH, Krause HM. Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide. Nature. 1996;379:162-165.
    • (1996) Nature , vol.379 , pp. 162-165
    • Copeland, J.W.1    Nasiadka, A.2    Dietrich, B.H.3    Krause, H.M.4
  • 33
    • 0032474748 scopus 로고    scopus 로고
    • Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1
    • Krosl J, Baban S, Krosl G, et al. Cellular proliferation and transformation induced by HOXB4 and HOXB3 proteins involves cooperation with PBX1. Oncogene. 1998;16:3403-3412.
    • (1998) Oncogene , vol.16 , pp. 3403-3412
    • Krosl, J.1    Baban, S.2    Krosl, G.3
  • 34
    • 0035253860 scopus 로고    scopus 로고
    • NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
    • Kroon E, Thorsteinsdottir U, Mayotte N, Nakamura T, Sauvageau G. NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. EMBO J. 2001;20:350-361.
    • (2001) EMBO J , vol.20 , pp. 350-361
    • Kroon, E.1    Thorsteinsdottir, U.2    Mayotte, N.3    Nakamura, T.4    Sauvageau, G.5
  • 35
    • 0028857266 scopus 로고
    • Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells
    • Krosl J, Damen JE, Krystal G, Humphries RK. Erythropoietin and interleukin-3 induce distinct events in erythropoietin receptor-expressing BA/F3 cells. Blood. 1995;85:50-56.
    • (1995) Blood , vol.85 , pp. 50-56
    • Krosl, J.1    Damen, J.E.2    Krystal, G.3    Humphries, R.K.4
  • 36
    • 0037396675 scopus 로고    scopus 로고
    • The competitive nature of HOXB4-transduced HSC is limited by PBX1: The generation of ultra-competitive stem cells retaining full differentiation potential
    • Krosl J, Beslu N, Mayotte N, Humphries RK, Sauvageau G. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity. 2003;18:561-571.
    • (2003) Immunity , vol.18 , pp. 561-571
    • Krosl, J.1    Beslu, N.2    Mayotte, N.3    Humphries, R.K.4    Sauvageau, G.5
  • 37
    • 0029998539 scopus 로고    scopus 로고
    • Interleukin-3 (IL-3) inhibits erythropoietin-induced differentiation in Ba/F3 cells via the IL-3 receptor alpha subunit
    • Krosl J, Damen JE, Krystal G, Humphries RK. Interleukin-3 (IL-3) inhibits erythropoietin-induced differentiation in Ba/F3 cells via the IL-3 receptor alpha subunit. J Biol Chem. 1996;271:27432-27437.
    • (1996) J Biol Chem , vol.271 , pp. 27432-27437
    • Krosl, J.1    Damen, J.E.2    Krystal, G.3    Humphries, R.K.4
  • 38
    • 0036090290 scopus 로고    scopus 로고
    • Over-expression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion
    • Thorsteinsdottir U, Mamo A, Kroon E, et al. Over-expression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion. Blood. 2002;99:121-129.
    • (2002) Blood , vol.99 , pp. 121-129
    • Thorsteinsdottir, U.1    Mamo, A.2    Kroon, E.3
  • 39
    • 0025205255 scopus 로고
    • Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy
    • Szilvassy SJ, Humphries RK, Lansdorp PM, Eaves AC, Eaves CJ. Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy. Proc Natl Acad Sci USA. 1990;87:8736-8740.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8736-8740
    • Szilvassy, S.J.1    Humphries, R.K.2    Lansdorp, P.M.3    Eaves, A.C.4    Eaves, C.J.5
  • 40
    • 0029928499 scopus 로고    scopus 로고
    • A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse
    • Rebel VI, Miller CL, Thornbury GR, et al. A comparison of long-term repopulating hematopoietic stem cells in fetal liver and adult bone marrow from the mouse. Exp Hematol. 1996;24:638-648.
    • (1996) Exp Hematol , vol.24 , pp. 638-648
    • Rebel, V.I.1    Miller, C.L.2    Thornbury, G.R.3
  • 41
    • 0034718780 scopus 로고    scopus 로고
    • AP-1 complex is effector of Hox-induced cellular proliferation and transformation
    • Krosl J, Sauvageau G. AP-1 complex is effector of Hox-induced cellular proliferation and transformation. Oncogene. 2000;19:5134-5141.
    • (2000) Oncogene , vol.19 , pp. 5134-5141
    • Krosl, J.1    Sauvageau, G.2
  • 42
    • 0034640526 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation
    • De Sepulveda P, Ilangumaran S, Rottapel R. Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation. J Biol Chem. 2000;275:14005-14008.
    • (2000) J Biol Chem , vol.275 , pp. 14005-14008
    • De Sepulveda, P.1    Ilangumaran, S.2    Rottapel, R.3
  • 43
    • 0025188837 scopus 로고
    • Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: A framework for understanding homeodomain-DNA interactions
    • Kissinger CR, Liu BS, Martin-Blanco E, Komberg TB, Pabo CO. Crystal structure of an engrailed homeodomain-DNA complex at 2.8 A resolution: a framework for understanding homeodomain-DNA interactions. Cell. 1990;63:579-590.
    • (1990) Cell , vol.63 , pp. 579-590
    • Kissinger, C.R.1    Liu, B.S.2    Martin-Blanco, E.3    Komberg, T.B.4    Pabo, C.O.5
  • 44
    • 0026002757 scopus 로고
    • Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions
    • Wolberger C, Vershon AK, Liu B, Johnson AD, Pabo CO. Crystal structure of a MAT alpha 2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell. 1991;67:517-528.
    • (1991) Cell , vol.67 , pp. 517-528
    • Wolberger, C.1    Vershon, A.K.2    Liu, B.3    Johnson, A.D.4    Pabo, C.O.5
  • 45
    • 0028947525 scopus 로고
    • Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins
    • Chang CP, Shen WF, Rozenfeld S, et al. Pbx proteins display hexapeptide-dependent cooperative DNA binding with a subset of Hox proteins. Genes Dev. 1995;9:663-674.
    • (1995) Genes Dev , vol.9 , pp. 663-674
    • Chang, C.P.1    Shen, W.F.2    Rozenfeld, S.3
  • 46
    • 0032927877 scopus 로고    scopus 로고
    • CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity
    • Kasper LH, Brindle PK, Schnabel CA, et al. CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity. Mol Cell Biol. 1999;19:764-776.
    • (1999) Mol Cell Biol , vol.19 , pp. 764-776
    • Kasper, L.H.1    Brindle, P.K.2    Schnabel, C.A.3
  • 47
    • 0037804796 scopus 로고    scopus 로고
    • Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1
    • Pineault N, Buske C, Feuring-Buske M, et al. Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood. 2003;01: 4529-4538.
    • (2003) Blood , vol.1 , pp. 4529-4538
    • Pineault, N.1    Buske, C.2    Feuring-Buske, M.3
  • 48
    • 1342304050 scopus 로고    scopus 로고
    • Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1
    • Pineault N, Abramovich C, Ohta H, Humphries RK. Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol. 2004;24:1907-1917.
    • (2004) Mol Cell Biol , vol.24 , pp. 1907-1917
    • Pineault, N.1    Abramovich, C.2    Ohta, H.3    Humphries, R.K.4
  • 49
    • 0036224321 scopus 로고    scopus 로고
    • The small GTPase Rap1 is an immediate downstream target for Hoxb4 transcriptional regulation
    • Morsi El-Kadi AS, in der Reiden. Durston A, Morgan R. The small GTPase Rap1 is an immediate downstream target for Hoxb4 transcriptional regulation. Mech Dev. 2002;113:131-139.
    • (2002) Mech Dev , vol.113 , pp. 131-139
    • Morsi El-Kadi, A.S.1    In Der Reiden2    Durston, A.3    Morgan, R.4
  • 50
    • 0033605694 scopus 로고    scopus 로고
    • c-myc intron element-binding proteins are required for 1,25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4
    • Pan Q, Simpson RU. c-myc intron element-binding proteins are required for 1,25-dihydroxyvitamin D3 regulation of c-myc during HL-60 cell differentiation and the involvement of HOXB4. J Biol Chem. 1999;274:8437-8444.
    • (1999) J Biol Chem , vol.274 , pp. 8437-8444
    • Pan, Q.1    Simpson, R.U.2
  • 51
    • 0035069929 scopus 로고    scopus 로고
    • Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression
    • Pan Q, Simpson RU. Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression. J Endocrinol. 2001;169: 153-159.
    • (2001) J Endocrinol , vol.169 , pp. 153-159
    • Pan, Q.1    Simpson, R.U.2
  • 52
    • 0037408147 scopus 로고    scopus 로고
    • TALE class homeodomain gene Irx5 is an immediate downstream target for Hoxb4 transcriptional regulation
    • Theokli C, Morsi El-Kadi AS, Morgan R. TALE class homeodomain gene Irx5 is an immediate downstream target for Hoxb4 transcriptional regulation. Dev Dyn. 2003;227:48-55.
    • (2003) Dev Dyn , vol.227 , pp. 48-55
    • Theokli, C.1    Morsi El-Kadi, A.S.2    Morgan, R.3
  • 53
    • 0345731230 scopus 로고    scopus 로고
    • FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, is directly regulated by Hoxb4 in the notochord
    • Morgan R, Nalliah A, Morsi El-Kadi AS. FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, is directly regulated by Hoxb4 in the notochord. Dev Biol. 2004;265:105-112.
    • (2004) Dev Biol , vol.265 , pp. 105-112
    • Morgan, R.1    Nalliah, A.2    Morsi El-Kadi, A.S.3
  • 54
    • 0034787503 scopus 로고    scopus 로고
    • Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development
    • Inbal A, Halachmi N, Dibner C, Frank D, Salzberg A. Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development. Development. 2001;128:3405-3413.
    • (2001) Development , vol.128 , pp. 3405-3413
    • Inbal, A.1    Halachmi, N.2    Dibner, C.3    Frank, D.4    Salzberg, A.5
  • 55
    • 0037162712 scopus 로고    scopus 로고
    • The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper
    • Lohmann I, McGinnis N, Bodmer M, McGinnis W. The Drosophila Hox gene deformed sculpts head morphology via direct regulation of the apoptosis activator reaper. Cell. 2002;110:457-466.
    • (2002) Cell , vol.110 , pp. 457-466
    • Lohmann, I.1    McGinnis, N.2    Bodmer, M.3    McGinnis, W.4
  • 56
    • 0033521623 scopus 로고    scopus 로고
    • Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation
    • Li X, Murre C, McGinnis W. Activity regulation of a Hox protein and a role for the homeodomain in inhibiting transcriptional activation. EMBO J. 1999;18:198-211.
    • (1999) EMBO J , vol.18 , pp. 198-211
    • Li, X.1    Murre, C.2    McGinnis, W.3
  • 57
    • 0142214646 scopus 로고    scopus 로고
    • Thrombopoietin stimulates Hoxb4 expression: An explanation for the favorable effects of TPO on hematopoietic stem cells
    • Kirito K, Fox N, Kaushansky K. Thrombopoietin stimulates Hoxb4 expression: an explanation for the favorable effects of TPO on hematopoietic stem cells. Blood. 2003;102:3172-3178.
    • (2003) Blood , vol.102 , pp. 3172-3178
    • Kirito, K.1    Fox, N.2    Kaushansky, K.3
  • 58
    • 0037737728 scopus 로고    scopus 로고
    • A role for Wnt signalling in self-renewal of haematopoietic stem cells
    • Reya T, Duncan AW, Ailles L, et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 2003;423:409-414.
    • (2003) Nature , vol.423 , pp. 409-414
    • Reya, T.1    Duncan, A.W.2    Ailles, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.