Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments

Oncogene

Volumn 18, Issue 2, 1999, Pages 551-557

  De Fromentel, Claude Caron ^a,c   Gruel, Nadége ^e   Venot, Corinne ^a   Debussche, Laurent ^a   Conseiller, Emmanuel ^a   Dureuil, Christine ^a   Teillaud, Jean Luc ^b   Tocque, Bruno ^a,d   Bracco, Laurent ^a,d  

^a SANOFI   (France)

^b INSTITUT CURIE   (France)

^c INSTITUT COCHIN   (France)

^d ExonHit Therapeutics   (France)

^e NONE

Author keywords

Gene therapy; Intracellular immunization; p53; scFv

Indexed keywords

DNA BINDING PROTEIN; MONOCLONAL ANTIBODY; PROTEIN P53;

ARTICLE; CANCER THERAPY; EXPRESSION VECTOR; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; TUMOR CELL; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; BASE SEQUENCE; DNA PRIMERS; GENETIC VECTORS; HUMANS; IMMUNOGLOBULIN FRAGMENTS; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0005382256     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202338     Document Type: Article

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