Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cancer cells: Enhanced intracellular stability of novel sFv-Fc intrabodies

Journal of Immunological Methods

Volumn 263, Issue 1-2, 2002, Pages 149-167

  Strube, Randall W ^a,b   Chen, Si Yi ^b  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

Author keywords

Breast cancer; Cyclin E; Fc fusion protein; Intrabody; Recombinant antibody; Single chain antibody

Indexed keywords

CYCLIN E; HYBRID PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL NUCLEUS; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; HYBRIDOMA CELL CULTURE; IMMUNOFLUORESCENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; BREAST NEOPLASMS; CELL DIVISION; CERCOPITHECUS AETHIOPS; CLONING, MOLECULAR; COS CELLS; CYCLIN E; DNA, COMPLEMENTARY; GENE EXPRESSION; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INTRACELLULAR FLUID; MICE; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; TUMOR CELLS, CULTURED;

EID: 0036570976     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(02)00035-2     Document Type: Article

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