메뉴 건너뛰기




Volumn 5, Issue 5, 1998, Pages 635-644

Intrabody-mediated knockout of the high-affinity IL-2 receptor in primary human T cells using a bicistronic lentivirus vector

Author keywords

IL 2R ; IRES; Lentivirus vector; Single chain antibody; VSV G protein

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; RECEPTOR ANTIBODY;

EID: 0031832695     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300644     Document Type: Article
Times cited : (28)

References (60)
  • 1
    • 0024460181 scopus 로고
    • Improved retroviral vectors for gene transfer and expression
    • Miller AD, Rosman GJ. Improved retroviral vectors for gene transfer and expression. Biotechniques 1989; 7: 980-982.
    • (1989) Biotechniques , vol.7 , pp. 980-982
    • Miller, A.D.1    Rosman, G.J.2
  • 2
    • 0029799638 scopus 로고    scopus 로고
    • Gene therapy in the United States: A five-year status report
    • Ross G et al. Gene therapy in the United States: a five-year status report. Hum Gene Ther 1996; 7: 1781-1790.
    • (1996) Hum Gene Ther , vol.7 , pp. 1781-1790
    • Ross, G.1
  • 3
    • 0027158091 scopus 로고
    • Integration of murine leukemia virus DNA depends upon mitosis
    • Roe TY, Reynolds TC, Yu G, Brown PO. Integration of murine leukemia virus DNA depends upon mitosis. EMBO J 1993; 12: 2099-2108.
    • (1993) EMBO J , vol.12 , pp. 2099-2108
    • Roe, T.Y.1    Reynolds, T.C.2    Yu, G.3    Brown, P.O.4
  • 4
    • 0028055281 scopus 로고
    • Passage through mitosis is required for onco-retroviruses but not the human immunodeficiency virus
    • Lewis PF, Emerman M. Passage through mitosis is required for onco-retroviruses but not the human immunodeficiency virus. J Virol 1994; 68: 510-516.
    • (1994) J Virol , vol.68 , pp. 510-516
    • Lewis, P.F.1    Emerman, M.2
  • 5
    • 0026654682 scopus 로고
    • Human immunodeficiency virus infection of cells arrested in the cell cycle
    • Lewis P, Hensel M, Emerman M. Human immunodeficiency virus infection of cells arrested in the cell cycle. EMBO J 1992; 11: 3053-3058.
    • (1992) EMBO J , vol.11 , pp. 3053-3058
    • Lewis, P.1    Hensel, M.2    Emerman, M.3
  • 6
    • 0026770379 scopus 로고
    • Active nuclear import of human immunodeficiency virus type 1 pre-integration complexes
    • Burinsky MJ et al. Active nuclear import of human immunodeficiency virus type 1 pre-integration complexes. Proc Natl Acad Sci USA 1992; 89: 6580-6584.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 6580-6584
    • Burinsky, M.J.1
  • 7
    • 0027162620 scopus 로고
    • Human immunodeficiency virus type 1 DNA synthesis, integration and efficient viral replication in growth-arrested T cells
    • Li G, Simm M, Potash MJ, Volsky DJ. Human immunodeficiency virus type 1 DNA synthesis, integration and efficient viral replication in growth-arrested T cells. J Virol 1993; 67: 3969-3977.
    • (1993) J Virol , vol.67 , pp. 3969-3977
    • Li, G.1    Simm, M.2    Potash, M.J.3    Volsky, D.J.4
  • 8
    • 0027376309 scopus 로고
    • A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
    • Bukrinsky MI et al. A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells. Nature 1993; 365: 666-669.
    • (1993) Nature , vol.365 , pp. 666-669
    • Bukrinsky, M.I.1
  • 9
    • 0028821383 scopus 로고
    • HIV-1 infection of non-dividing cells: C-terminal ryrosine phosphorylation of the viral matrix protein is a key regulator
    • Gallay P, Swingler S, Aiken C, Trono D. HIV-1 infection of non-dividing cells: C-terminal ryrosine phosphorylation of the viral matrix protein is a key regulator. Cell 1995; 80: 379-388.
    • (1995) Cell , vol.80 , pp. 379-388
    • Gallay, P.1    Swingler, S.2    Aiken, C.3    Trono, D.4
  • 10
    • 0028239060 scopus 로고
    • The vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing cells
    • Heinzinger NK et al. The vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing cells. Proc Natl Acad Sci USA 1994; 91: 7311-7315.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7311-7315
    • Heinzinger, N.K.1
  • 11
    • 0030467991 scopus 로고    scopus 로고
    • Transduction of nondividing cells using pseudotyped high-titer HIV type 1 particles
    • Reiser J et al. Transduction of nondividing cells using pseudotyped high-titer HIV type 1 particles. Proc Natl Acad Sci USA 1996; 93: 15266-15271.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15266-15271
    • Reiser, J.1
  • 12
    • 0029996147 scopus 로고    scopus 로고
    • In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
    • Naldini L et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996; 272: 263- 267.
    • (1996) Science , vol.272 , pp. 263-267
    • Naldini, L.1
  • 13
    • 0025957564 scopus 로고
    • Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range
    • Landau NR, Page KA, Littman DR. Pseudotyping with human T-cell leukemia virus type I broadens the human immunodeficiency virus host range. J Virol 1991; 65: 162-169.
    • (1991) J Virol , vol.65 , pp. 162-169
    • Landau, N.R.1    Page, K.A.2    Littman, D.R.3
  • 14
    • 0026562720 scopus 로고
    • Detection of replication-competent and pseudo-typed human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene
    • Kimpton J, Emerman M. Detection of replication-competent and pseudo-typed human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated β-galactosidase gene. J Virol 1992; 66: 2232-2239.
    • (1992) J Virol , vol.66 , pp. 2232-2239
    • Kimpton, J.1    Emerman, M.2
  • 15
    • 0025204822 scopus 로고
    • CD4-independent infection by human immunodeficiency virus type 1 after phenotypic mixing with human T-cell leukemia viruses
    • Lusso P, Lori F, Gallo RC. CD4-independent infection by human immunodeficiency virus type 1 after phenotypic mixing with human T-cell leukemia viruses. J Virol 1990; 64: 6341-6344.
    • (1990) J Virol , vol.64 , pp. 6341-6344
    • Lusso, P.1    Lori, F.2    Gallo, R.C.3
  • 16
    • 0025249864 scopus 로고
    • Phenotypic mixing between human immunodeficiency virus and vesicular stomatitis virus or herpes simplex virus
    • Zhu Z, Chen SSL, Huang SH. Phenotypic mixing between human immunodeficiency virus and vesicular stomatitis virus or herpes simplex virus. J AIDS 1990; 3: 215-219.
    • (1990) J AIDS , vol.3 , pp. 215-219
    • Zhu, Z.1    Chen, S.S.L.2    Huang, S.H.3
  • 17
    • 0029872245 scopus 로고    scopus 로고
    • + cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G
    • + cells with a human immunodeficiency virus type 1-based retroviral vector pseudotyped with vesicular stomatitis virus envelope glycoprotein G. J Virol 1996; 70: 2581-2585.
    • (1996) J Virol , vol.70 , pp. 2581-2585
    • Akkina, R.K.1
  • 18
    • 0029993519 scopus 로고    scopus 로고
    • 2 accumulation by a mechanism which differs from DNA damage checkpoint control
    • 2 accumulation by a mechanism which differs from DNA damage checkpoint control. J Virol 1996; 70: 2324-2331.
    • (1996) J Virol , vol.70 , pp. 2324-2331
    • Bartz, S.R.1    Rogel, M.E.2    Emerman, M.3
  • 19
    • 0028095020 scopus 로고
    • A general method for the generation of high-titer, pantropic retroviral vectors: Highly efficient infection of primary hepatocytes
    • Yee JK et al. A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. Proc Natl Acad Sci USA 1994; 91: 9564-9568.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9564-9568
    • Yee, J.K.1
  • 20
    • 0021726790 scopus 로고
    • Genes with promoters in retrovirus vector scan be independently suppressed by an epigeneric mechanism
    • Emerman M, Temin H. Genes with promoters in retrovirus vector scan be independently suppressed by an epigeneric mechanism. Cell 1984; 39: 459-467.
    • (1984) Cell , vol.39 , pp. 459-467
    • Emerman, M.1    Temin, H.2
  • 21
    • 0023045648 scopus 로고
    • Comparison of promoter suppression in avian and murine retrovirus vectors
    • Emerman M, Temin HM. Comparison of promoter suppression in avian and murine retrovirus vectors. Nucleic Acids Res 1986; 14: 9318-9396.
    • (1986) Nucleic Acids Res , vol.14 , pp. 9318-9396
    • Emerman, M.1    Temin, H.M.2
  • 22
    • 0023904379 scopus 로고
    • Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes
    • Bowtell DD, Cory S, Johnson GR, Gonda TJ. Comparison of expression in hemopoietic cells by retroviral vectors carrying two genes. J Virol 1988; 62: 2464-2473.
    • (1988) J Virol , vol.62 , pp. 2464-2473
    • Bowtell, D.D.1    Cory, S.2    Johnson, G.R.3    Gonda, T.J.4
  • 23
    • 7144262725 scopus 로고
    • High mutation rate of a spleen necrosis virus-based retrovirus vector
    • Dougherty JP, Temin HM. High mutation rate of a spleen necrosis virus-based retrovirus vector. Mol Cell Biol 1986; 168: 87-95.
    • (1986) Mol Cell Biol , vol.168 , pp. 87-95
    • Dougherty, J.P.1    Temin, H.M.2
  • 24
    • 0025945901 scopus 로고
    • Internal initiation of translation in retroviral vectors carrying picorna-virus 5′ nontranslated regions
    • Adam MA, Ramesh N, Miller DA, Osborne WRA. Internal initiation of translation in retroviral vectors carrying picorna-virus 5′ nontranslated regions. J Virol 1991; 65: 4985-4990.
    • (1991) J Virol , vol.65 , pp. 4985-4990
    • Adam, M.A.1    Ramesh, N.2    Miller, D.A.3    Osborne, W.R.A.4
  • 25
    • 0027477458 scopus 로고
    • Characterization of a bicistronic retroviral vector composed of the swine vesicular disease virus internal ribosome entry site
    • Chen BF, Hwang LH, Chen DS. Characterization of a bicistronic retroviral vector composed of the swine vesicular disease virus internal ribosome entry site. J Virol 1993; 67: 2142-2148.
    • (1993) J Virol , vol.67 , pp. 2142-2148
    • Chen, B.F.1    Hwang, L.H.2    Chen, D.S.3
  • 26
    • 0026558141 scopus 로고
    • A spleen necrosis virus-based retroviral vector which expresses two genes from a dicistronic mRNA
    • Koo HM et al. A spleen necrosis virus-based retroviral vector which expresses two genes from a dicistronic mRNA. Virology 1992; 186: 669-675.
    • (1992) Virology , vol.186 , pp. 669-675
    • Koo, H.M.1
  • 27
    • 8244221014 scopus 로고    scopus 로고
    • Inhibition of early and late events of the HTV-1 replication cycle by cytoplasmic Fab intrabodies against the matrix protein, p17
    • Levin R et al. Inhibition of early and late events of the HTV-1 replication cycle by cytoplasmic Fab intrabodies against the matrix protein, p17. Molec Med 1997; 2: 96-110.
    • (1997) Molec Med , vol.2 , pp. 96-110
    • Levin, R.1
  • 28
    • 0028255868 scopus 로고
    • Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector
    • Aran JM, Gottesman MM, Pastan I. Drug-selected coexpression of human glucocerebrosidase and P-glycoprotein using a bicistronic vector. Proc Natl Acad Sci USA 1994; 91: 3176-3180.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3176-3180
    • Aran, J.M.1    Gottesman, M.M.2    Pastan, I.3
  • 29
    • 0026588638 scopus 로고
    • Retroviral vectors containing putative internal ribosome entry sites: Development of a polycistronic gene transfer system and applications to human gene therapy
    • Morgan RA et al. Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy. Nucleic Acids Res 1992; 20: 1293-1299.
    • (1992) Nucleic Acids Res , vol.20 , pp. 1293-1299
    • Morgan, R.A.1
  • 30
    • 0026053301 scopus 로고
    • Regulation of HIV gene expression by RNA-protein interactions
    • Rosen CA. Regulation of HIV gene expression by RNA-protein interactions. Trends Genet 1991; 7: 9-14.
    • (1991) Trends Genet , vol.7 , pp. 9-14
    • Rosen, C.A.1
  • 31
    • 0025342694 scopus 로고
    • HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure
    • Zack JA et al. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell 1990; 61: 213-222.
    • (1990) Cell , vol.61 , pp. 213-222
    • Zack, J.A.1
  • 32
    • 0026526144 scopus 로고
    • Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle
    • Zack JA, Haislip AM, Krogstad P, Chen ISY. Incompletely reverse-transcribed human immunodeficiency virus type 1 genomes in quiescent cells can function as intermediates in the retroviral life cycle. J Virol 1992; 66: 1717-1725.
    • (1992) J Virol , vol.66 , pp. 1717-1725
    • Zack, J.A.1    Haislip, A.M.2    Krogstad, P.3    Chen, I.S.Y.4
  • 33
    • 0028958338 scopus 로고
    • Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro
    • Spina CA, Guatelli JC, Richman DD. Establishment of a stable, inducible form of human immunodeficiency virus type 1 DNA in quiescent CD4 lymphocytes in vitro. J Virol 1995; 69: 2977- 2988.
    • (1995) J Virol , vol.69 , pp. 2977-2988
    • Spina, C.A.1    Guatelli, J.C.2    Richman, D.D.3
  • 34
    • 0029091047 scopus 로고
    • + T cells are infectible by human immunodeficiency virus but do not release virus after activation
    • + T cells are infectible by human immunodeficiency virus but do not release virus after activation. J Virol 1995; 69; 5659-5665.
    • (1995) J Virol , vol.69 , pp. 5659-5665
    • Tang, S.1    Patterson, B.2    Levy, J.A.3
  • 35
    • 0025238945 scopus 로고
    • HIV- 1 replication is controlled at the level of T cell activation and proviral integration
    • Stevenson M, Stanwick TL, Dempsey MP, Lamonica CA. HIV- 1 replication is controlled at the level of T cell activation and proviral integration. EMBO J 1990; 9: 1551-1560.
    • (1990) EMBO J , vol.9 , pp. 1551-1560
    • Stevenson, M.1    Stanwick, T.L.2    Dempsey, M.P.3    Lamonica, C.A.4
  • 36
    • 0026054892 scopus 로고
    • Quiescent T lymphocytes as an inducible virus reservoir in HIV- 1 infection
    • Bukrinsky MI, Stanwick TL, Dempsey MP, Stevenson M. Quiescent T lymphocytes as an inducible virus reservoir in HIV- 1 infection. Science 1991; 254: 423-427.
    • (1991) Science , vol.254 , pp. 423-427
    • Bukrinsky, M.I.1    Stanwick, T.L.2    Dempsey, M.P.3    Stevenson, M.4
  • 37
    • 0024500613 scopus 로고
    • Initiation of protein synthesis by internal entry of ribosomes into the 5′ nontranslated region of encephalomyocarditis virus RNA in vivo
    • Jang SK, Davies MV, Kaufman RJ, Wimmer E. Initiation of protein synthesis by internal entry of ribosomes into the 5′ nontranslated region of encephalomyocarditis virus RNA in vivo. J Virol 1989; 63: 1651-1660.
    • (1989) J Virol , vol.63 , pp. 1651-1660
    • Jang, S.K.1    Davies, M.V.2    Kaufman, R.J.3    Wimmer, E.4
  • 38
    • 0028955535 scopus 로고
    • Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the α subunit of the receptor
    • Richardson JH, Sodroski JG, Waldmann TA, Marasco WA. Phenotypic knockout of the high-affinity human interleukin 2 receptor by intracellular single-chain antibodies against the α subunit of the receptor. Proc Natl Acad Sci USA 1995; 92: 3137-3141
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3137-3141
    • Richardson, J.H.1    Sodroski, J.G.2    Waldmann, T.A.3    Marasco, W.A.4
  • 39
    • 0030698323 scopus 로고    scopus 로고
    • Inducible knockout of the interleukin-2 receptor α. chain: Expression of the high-affinity IL-2 receptor is not required for the in vitro growth of HTLV-I-transformed cell lines
    • Richardson JH, Waldmann TA, Sodroski JG, Marasco WA. Inducible knockout of the interleukin-2 receptor α. chain: expression of the high-affinity IL-2 receptor is not required for the in vitro growth of HTLV-I-transformed cell lines. Virology 1997; 237: 209-216.
    • (1997) Virology , vol.237 , pp. 209-216
    • Richardson, J.H.1    Waldmann, T.A.2    Sodroski, J.G.3    Marasco, W.A.4
  • 40
    • 0027405991 scopus 로고
    • The IL-2 receptor complex: Its structure, function and target genes
    • Minami Y, Kono T, Miyazaki T, Taniguchi T. The IL-2 receptor complex: its structure, function and target genes. Annu Rev Immunol 1993; 11: 245-267.
    • (1993) Annu Rev Immunol , vol.11 , pp. 245-267
    • Minami, Y.1    Kono, T.2    Miyazaki, T.3    Taniguchi, T.4
  • 41
    • 0001888446 scopus 로고
    • Regulation of HIV gene expression
    • Cullen BR. Regulation of HIV gene expression. AIDS 1995; 9 (Suppl. A): S19-S32.
    • (1995) AIDS , vol.9 , Issue.SUPPL. A
    • Cullen, B.R.1
  • 42
    • 0025906388 scopus 로고
    • A generic intron increases gene expression in transgenic mice
    • Choi T, Huang M, German C, Jaenisch R A generic intron increases gene expression in transgenic mice. Mol Cell Biol 1991; 11: 3070-3074.
    • (1991) Mol Cell Biol , vol.11 , pp. 3070-3074
    • Choi, T.1    Huang, M.2    German, C.3    Jaenisch, R.4
  • 44
    • 0028805939 scopus 로고
    • Development and analysis of retroviral vectors expressing human factor VIII as a potential gene therapy for hemophilia A
    • Chuah MK, Vandendriessche T, Morgan RA. Development and analysis of retroviral vectors expressing human factor VIII as a potential gene therapy for hemophilia A. Hum Gene Ther 1995; 6: 1363-1377.
    • (1995) Hum Gene Ther , vol.6 , pp. 1363-1377
    • Chuah, M.K.1    Vandendriessche, T.2    Morgan, R.A.3
  • 45
    • 0025269031 scopus 로고
    • Intervening sequences increase efficiency of RNA 3′ processing and accumulation of cytoplasmic RNA
    • Huang MT, German CM. Intervening sequences increase efficiency of RNA 3′ processing and accumulation of cytoplasmic RNA. Nucleic Acids Res 1990; 18: 937-947.
    • (1990) Nucleic Acids Res , vol.18 , pp. 937-947
    • Huang, M.T.1    German, C.M.2
  • 47
    • 0028784289 scopus 로고
    • Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment
    • Willerford DM et al. Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995; 3: 521-530.
    • (1995) Immunity , vol.3 , pp. 521-530
    • Willerford, D.M.1
  • 48
    • 0023620692 scopus 로고
    • Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia/lymphoma virus
    • Hori T et al. Establishment of an interleukin 2-dependent human T cell line from a patient with T cell chronic lymphocytic leukemia who is not infected with human T cell leukemia/lymphoma virus. Blood 1987; 70: 1069-1072.
    • (1987) Blood , vol.70 , pp. 1069-1072
    • Hori, T.1
  • 49
    • 0026051132 scopus 로고
    • Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector
    • Poznansky M et al. Gene transfer into human lymphocytes by a defective human immunodeficiency virus type 1 vector. J Virol 1991; 5: 532-536.
    • (1991) J Virol , vol.5 , pp. 532-536
    • Poznansky, M.1
  • 50
    • 0025096107 scopus 로고
    • Visna virus encodes a post-transcriptional regulator of viral structural gene expression
    • Tiley LS et al. Visna virus encodes a post-transcriptional regulator of viral structural gene expression. Proc Natl Acad Sci USA 1990; 87: 7497-7501.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7497-7501
    • Tiley, L.S.1
  • 51
    • 0025005828 scopus 로고
    • Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity
    • Page KA, Landau MR, Littman DR. Construction and use of a human immunodeficiency virus vector for analysis of virus infectivity. J Virol 1990; 64: 5270-5276.
    • (1990) J Virol , vol.64 , pp. 5270-5276
    • Page, K.A.1    Landau, M.R.2    Littman, D.R.3
  • 52
    • 0026742288 scopus 로고
    • Mutations within the env gene of Mason-Pfizer monkey virus: Effects on protein transport and SU-TM association
    • Brody BA, Hunter E. Mutations within the env gene of Mason-Pfizer monkey virus: effects on protein transport and SU-TM association. J Virol 1992; 66: 3422-3475.
    • (1992) J Virol , vol.66 , pp. 3422-3475
    • Brody, B.A.1    Hunter, E.2
  • 53
    • 0023375898 scopus 로고
    • Nucleotide sequence analysis of the env gene and its flanking regions of the human spumaretrovirus reveals two novel genes
    • Flugel RM, Rethwilm A, Maurer B, Darai G. Nucleotide sequence analysis of the env gene and its flanking regions of the human spumaretrovirus reveals two novel genes. EMBO J 1987; 6: 2077-2084.
    • (1987) EMBO J , vol.6 , pp. 2077-2084
    • Flugel, R.M.1    Rethwilm, A.2    Maurer, B.3    Darai, G.4
  • 54
    • 0025268873 scopus 로고
    • Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants
    • Helseth E et al. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants. J Virol 1990; 64: 2416-2420.
    • (1990) J Virol , vol.64 , pp. 2416-2420
    • Helseth, E.1
  • 55
    • 0022381480 scopus 로고
    • Phenotypic and functional analysis of T cells cloned directly from the blood and cerebrospinal fluid of patients with multiple sclerosis
    • Hafler DA, Buchsbaum M, Johnson D, Weiner HL. Phenotypic and functional analysis of T cells cloned directly from the blood and cerebrospinal fluid of patients with multiple sclerosis. Ann Neurol 1985; 18: 451-458.
    • (1985) Ann Neurol , vol.18 , pp. 451-458
    • Hafler, D.A.1    Buchsbaum, M.2    Johnson, D.3    Weiner, H.L.4
  • 56
    • 0025281329 scopus 로고
    • Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages
    • Robert-Guroff M et al. Structure and expression of tat-, rev-, and nef-specific transcripts of human immunodeficiency virus type 1 in infected lymphocytes and macrophages. J Virol 1990; 64: 3391-3398.
    • (1990) J Virol , vol.64 , pp. 3391-3398
    • Robert-Guroff, M.1
  • 57
    • 0025335833 scopus 로고
    • Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1
    • Swartz S et al. Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1. J Virol 1990; 64: 2519-2529.
    • (1990) J Virol , vol.64 , pp. 2519-2529
    • Swartz, S.1
  • 58
    • 0027494083 scopus 로고
    • Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication and infectivity
    • Purcell DF, Martin MA. Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication and infectivity. J Virol 1993; 67: 6365- 6378.
    • (1993) J Virol , vol.67 , pp. 6365-6378
    • Purcell, D.F.1    Martin, M.A.2
  • 59
    • 0029026576 scopus 로고
    • Regulation of HIV-1 gene expression by the transactivator protein Tat
    • Gaynor RB. Regulation of HIV-1 gene expression by the transactivator protein Tat. Curr Top Microbiol Immunol 1995; 193: 51-77.
    • (1995) Curr Top Microbiol Immunol , vol.193 , pp. 51-77
    • Gaynor, R.B.1
  • 60
    • 0030774549 scopus 로고    scopus 로고
    • Taking a new TAK on tat transactivation
    • Jones KA. Taking a new TAK on tat transactivation. Genes Dev 1997; 11: 2593-2599.
    • (1997) Genes Dev , vol.11 , pp. 2593-2599
    • Jones, K.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.