Generation and functional characterization of intracellular antibodies interacting with the kinase domain of human EGF receptor

Oncogene

Volumn 22, Issue 10, 2003, Pages 1557-1567

  Hyland, Stephen ^a   Beerli, Roger R ^b,c,d   Barbas III, Carlos F ^b   Hynes, Nancy E ^c   Wels, Winfried ^a  

^a INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH   (Switzerland)

^d CYTOS BIOTECHNOLOGY AG   (Switzerland)

Author keywords

Epidermal growth factor receptor; Intrabody; Receptor tyrosine kinase; Single chain Fv antibody; Yeast two hybrid

Indexed keywords

ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHOTRANSFERASE;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL MEMBRANE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DISULFIDE BOND; ENDOPLASMIC RETICULUM; EUKARYOTIC CELL; GENE EXPRESSION; IMMUNOPRECIPITATION; NONHUMAN; ONCOGENE NEU; PHAGE DISPLAY; PLASMID; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BACTERIOPHAGES; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CELL MEMBRANE; COS CELLS; CYTOPLASM; GENE LIBRARY; GENETIC ENGINEERING; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA; EUKARYOTA;

EID: 0037434983     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206299     Document Type: Article

References (58)

1. Altenschmidt U, Schmidt M, Groner B and Wels W. (1997). Int. J. Cancer, 73, 117-124.
2. Andris-Widhopf J, Steinberger P, Fuller R, Rader C and Barbas III CF. (2001). Phage Display: A Laboratory Manual. Barbas III CF, Burton DR, Scott JK and Silverman GJ (eds). Cold Spring Harbor Laboratory Press: Plainview, NY, pp. 9.1-9.113.
3. Bach H, Mazor Y, Shaky S, Shoham-Lev A, Berdichevsky Y, Gutnick DL and Benhar I. (2001). J. Mol. Biol., 312, 79-93.
4. Barbas III CF, Burton DR, Scott JK and Silverman GJ (2001). Phage Display: A Laboratory Manual. Cold Spring Harbor Laboratory Press: Plainview, NY.
5. Barbas III CF, Kang AS, Lerner RA and Benkovic SJ. (1991). Proc. Natl. Acad. Sci. USA, 88, 7978-7982.
6. Baselga J, Pfister D, Cooper MR, Cohen R, Burtness B, Bos M, D'Andrea G, Seidman A, Norton L, Gunnett K, Falcey J, Anderson V, Waksal H and Mendelsohn J. (2000). J. Clin. Oncol., 18, 904-914.
7. Beerli RR, Graus-Porta D, Woods-Cook K, Chen X, Yarden Y and Hynes NE (1995). Mol. Cell. Biol., 15, 6496-6505.
8. Beerli RR, Wels W and Hynes NE (1994a). Biochem. Biophys. Res. Commun., 204, 666-672.
9. Beerli RR, Wels W and Hynes NE (1994b). J. Biol. Chem., 269, 23931-23936.
10. Beerli RR, Wels W and Hynes NE (1996). Breast Cancer Res. Treat., 38, 11-17.
11. Biocca S, Pierandrei-Amaldi P, Campioni N and Cattaneo A. (1994). Biotechnology (NY), 12, 396-399.
12. Biocca S, Ruberti F, Tafani M, Pierandrei-Amaldi P and Cattaneo A. (1995). Biotechnology (NY), 13, 1110-1115.
13. Cardinale A, Filesi I and Biocca S. (2001). Eur. J. Biochem., 268, 268-277.
14. Cattaneo A and Biocca S. (1999). Trends Biotechnol., 17, 115-121.
15. De Jaeger G, Fiers E, Eeckhout D and Depicker A. (2000). FEBS Lett., 467, 316-320.
16. Deshane J, Loechel F, Conry RM, Siegal GP, King CR and Curiel DT. (1994). Gene Ther., 1, 332-337.
17. Downward J, Yarden Y, Mayes E, Scrace G, Totty N, Stockwell P, Ullrich A, Schlessinger J and Waterfield MD. (1984). Nature, 307, 521-527.
18. Duan L, Bagasra O, Laughlin MA, Oakes JW and Pomerantz RJ. (1994). Proc. Natl. Acad. Sci. USA, 91, 5075-5079.
19. Gargano N and Cattaneo A. (1997). J. Gen. Virol., 78, 2591-2599.
20. Goncalves J, Silva F, Freitas-Vieira A, Santa-Marta M, Malho R, Yang X, Gabuzda D and Barbas III C (2002). J. Biol. Chem., 277, 32036-32045.
21. Graus-Porta D, Beerli RR, Daly JM and Hynes NE. (1997). EMBO J., 16, 1647-1655.
22. Gschwind A, Zwick E, Prenzel N, Leserer M and Ullrich A. (2001). Oncogene, 20, 1594-1600.
23. Gullick WJ. (1991). Br. Med. Bull., 47, 87-98.
24. Gullick WJ, Downward J and Waterfield MD (1985). EMBO J., 4, 2869-2877.
25. Hills D, Rowlinson-Busza G and Gullick WJ. (1995). Int. J. Cancer, 63, 537-543.
26. Holliger P, Prospero T and Winter G. (1993). Proc. Natl. Acad. Sci. USA, 90, 6444-6448.
27. Jannot CB, Beerli RR, Mason S, Gullick WJ and Hynes NE. (1996). Oncogene, 13, 275-282.
28. Jermutus L, Honegger A, Schwesinger F, Hanes J and Plückthun A. (2001). Proc. Natl. Acad. Sci. USA, 98, 75-80.
29. Kabat EA, Wu TT, Perry HM, Gottesman KS and Foeller C. (1991). Sequences of Proteins of Immunological Interest, 5 edn. National Institutes of Health: Bethesda.
30. Karunagaran D, Tzahar E, Beerli RR, Chen X, Graus-Porta D, Ratzkin BJ, Seger R, Hynes NE and Yarden Y. (1996). EMBO J., 15, 254-264.
31. Kile BT, Schulman BA, Alexander WS, Nicola NA, Martin HM and Hilton DJ. (2002). Trends Biochem. Sci., 27, 235-241.
32. King CR, Kraus MH and Aaronson SA. (1985). Science, 229, 974-976.
33. Klapper LN, Kirschbaum MH, Sela M and Yarden Y. (2000). Adv. Cancer Res., 77, 25-79.
34. Lener M, Horn IR, Cardinale A, Messina S, Nielsen UB, Rybak SM, Hoogenboom HR, Cattaneo A and Biocca S. (2000). Eur. J. Biochem., 267, 1196-1205.
35. Marasco WA. (1995). Immunotechnology, 1, 1-19.
36. Marasco WA. (1997). Gene Ther., 4, 11-15.
37. Martineau P, Jones P and Winter G. (1998). J. Mol. Biol., 280, 117-127.
38. Mendelsohn J. (1997). Clin. Cancer Res., 3, 2703-2707.
39. Mendelsohn J and Baselga J. (2000). Oncogene, 19, 6550-6565.
40. Mhashilkar AM, Bagley J, Chen SY, Szilvay AM, Helland DG and Marasco WA. (1995). EMBO J., 14, 1542-1551.
41. Ohage EC, Wirtz P, Barnikow J and Steipe B. (1999). J. Mol. Biol., 291, 1129-1134.
42. Olayioye MA, Neve RM, Lane HA and Hynes NE. (2000). EMBO J., 19, 3159-3167.
43. Parisien JP, Lau JF, Rodriguez JJ, Sullivan BM, Moscona A, Parks GD, Lamb RA and Horvath CM. (2001). Virology, 283, 230-239.
44. Persic L, Righi M, Roberts A, Hoogenboom HR, Cattaneo A and Bradbury A. (1997). Gene, 187, 1-8.
45. Proba K, Honegger A and Plückthun A. (1997). J. Mol. Biol., 265, 161-172.
46. Rader C and Barbas III CF (1997). Curr. Opin. Biotechnol., 8, 503-508.
47. Russo MW, Lukas TJ, Cohen S and Staros JV. (1985). J. Biol. Chem., 260, 5205-5208.
48. Shin DM, Donato NJ, Perez-Soler R, Shin HJ, Wu JY, Zhang P, Lawhorn K, Khuri FR, Glisson BS, Myers J, Clayman G, Pfister D, Falcey J, Waksal H, Mendelsohn J and Hong WK. (2001). Clin. Cancer Res., 7, 1204-1213.
49. Steinberger P, Andris-Widhopf J, Buhler B, Torbett BE and Barbas III CF (2000). Proc. Natl. Acad. Sci. USA, 97, 805-810.
50. Tse E, Lobato MN, Forster A, Tanaka T, Chung GT and Rabbitts TH. (2002). J. Mol. Biol., 317, 85-94.
51. Visintin M, Tse E, Axelson H, Rabbitts TH and Cattaneo A. (1999). Proc. Natl. Acad. Sci. USA, 96, 11723-11728.
52. Wörn A, Auf der Maur A, Escher D, Honegger A, Barberis A and Plückthun A. (2000). J. Biol. Chem., 275, 2795-2803.
53. Wörn A and Plückthun A. (1998). FEBS Lett., 427, 357-361.
54. Wörn A and Plückthun A. (2001). J. Mol. Biol., 305, 989-1010.
55. Xu JL and Davis MM. (2000). Immunity, 13, 37-45.
56. Yarden Y and Sliwkowski MX. (2001). Nat. Rev. Mol. Cell Biol., 2, 127-137.
57. Yi KS, Chung JH, Lee YH, Chung HG, Kim IJ, Suh BC, Kim E, Cocco L, Ryu SH and Sub PG. (2001). Oncogene, 20, 7954-7964.
58. Zhu Q, Zeng C, Huhalov A, Yao J, Turi TG, Danley D, Hynes T, Cong Y, DiMattia D, Kennedy S, Daumy G, Schaeffer E, Marasco WA and Huston JS. (1999). J. Immunol. Methods, 231, 207-222.