Ocular surface epithelia express mRNA for human beta defensin-2

Experimental Eye Research

Volumn 69, Issue 5, 1999, Pages 483-490

  McNamara, Nancy A ^a   Van, Rajana ^a   Tuchin, Oren S ^a   Fleiszig, Suzanne M J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Conjunctival epithelium; Corneal epithelium; Human beta defensin 2; Lipopolysaccharide; Pseudomonas aeruginosa

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENTARY DNA; DEFENSIN; MESSENGER RNA;

ARTICLE; BACTERIAL INFECTION; BACTERIUM CULTURE; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CORNEA EPITHELIUM; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; KERATITIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0032731116     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1006/exer.1999.0722     Document Type: Article

References (30)

1. Araki-Sasaki K., Ohashi Y., Sasabe T., Hayashi K., Watanabe H., Tano Y., Handa H. An SV40-immortalized human corneal epithelial cell line and its characterization. Invest. Ophthalmol. Vis. Sci. 36:1995;614-621.
2. Bartels J., Schluter C., Richter E., Noso N., Kulke R., Christophers E., Schroder J. Human dermal fibroblasts express eotaxin: molecular cloning, mRNA expression, an identification of eotaxin sequence variants. Biochem. Biophys. Res. Comm. 225:1996;1045-1051.
3. Bensch K., Raida M., Magert H., Schulz-Knappe P., Forssmann W. hBD-1: a novel beta-defensin from human plasma. FEBS Lett. 368:1995;331-335.
4. Bowman H. Peptide antibiotics and their role in innate immunity. Ann. Rev. Immunol. 13:1995;61-92.
5. Buehler P., Schein O., Stamler J., Al E. The increased risk of ulcerative keratitis among disposable soft contact lens users. Arch. Ophthalmol. 110:1992;1555-1558.
6. Cowell B., Wilcox M., Schneider R. Growth of Gram-negative bacteria in a simulated ocular environment. Aust. NZ J. Ophthalmol. 25:1997;S23-6.
7. Coyne M., Russell K., Coyle C., Goldberg J. The Pseudomonas aeruginosa algC gene encodes phosphoglucomutase, required for synthesis of a complete lipopolysaccharide core. J. Bacteriol. 176:1994;3500-3507.
8. Cryz S., Furer E., Gemanier R. Passive protection against Pseudomonas aeruginosa infection in an experimental leukopenic mouse model. Infect. Immun. 40:1983;659-664.
9. Cryz S., Sadoff J., Ohman D., Furer E. Characterization of the human immune response to Pseudomonas aeruginosa O-polysaccharide-toxin A conjugate vaccine. J. Lab. Clin. Med. 111:1988;701-707.
10. Diamond G., Zasloff M., Eck H., Brasseur M., Maloy W., Bevins C. Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA. Proc. Natl. Acad. Sci. USA. 88:1991;3952.
11. Fleiszig S., Zaidi T., Ramphal R., Pier G. Modulation of Pseudomonas aeruginosa adherence to the corneal surface by mucus. Infect. Immun. 62:1994;1799-1804.
12. Goldberg J., Hatano K., Pier P. Synthesis of lipopolysaccharide O side chains by Pseudomonas aeruginosa PAO1 requires the enzyme phosphomannomutase. J. Bacteriol. 175:1993;1605-1611.
13. Harder J., Bartels J., Christophers E., Schroder J. A peptide antibiotic from human skin. Nature. 387:1997;861.
14. Jarrell K., Kropinski A. Isolation and characterization of a bacteriophage specific for the lipopolysaccharide of rough derivatives ofPseudomonas aeruginosa strain PAO. J. Virol. 40:1981a;411-420.
15. Jarrell K., Kropinski A. Pseudomonas aeruginosa bacteriophage PLS27-lipopolysaccharide interactions. J. Virol. 40:1981b;411-420.
16. Knirel, Y. (1990). Polysaccharide antigens of, Pseudomonas aeruginosa. Critical Reviews in Microbiology 17, 273-304.
17. Kropinski A., Chan L., Milazzo F. The extraction and analysis of lipopolysaccharides from Pseudomonas aeruginosa strain PAO, and three rough mutants. Can. J. Microbiol. 25:1979;390-398.
18. Kropinski A., Jewell B., Kuzio J., Milazzo F., Berry D. Structure and functions of Pseudomonas aeruginosa lipopolysaccharides. Antibiot. Chemother. 36:1985;58.
19. Li J., Dohrman A., Gallup M., Miyata S., Gum J., Kim Y., Nadel J., Prince A., Basbaum C. Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc. Natl. Acad. Sci. USA. 94:1997;967-972.
20. McNamara, N. and Fleiszig, S. (1998). Human tear film components bind, Pseudomonas aeruginosa. Adv. Exp. Med. Bio. 438, 653-8.
21. Pier G., Grout M., Zaidi T., Olsen J., Johnson L., Yankaskas J., Goldberg J. Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections. Science. 271:1996;64-67.
22. Rietschel E., Brade H. Bacterial endotoxins. Scientific American. August:1992;54-61.
23. Schluter, C., Herrmann, F., Bartels, J., Kulke, R., Christophers, E. and Schroder, J. (1998). In preparation.
24. Schonwetter B., Stolzenberg E., Zasloff M. Epithelial antibiotics induced at sites of inflammation. Science. 267:1995.
25. Westphal O., Jann K. Bacterial lipopolysaccharides: extraction with phenol-water and further applications of the procedure. Meth. Carbohydr. Chem. 5:1965;83-91.
26. Wilhelmus K. Review of clinical experience with microbial keratitis associated with contact lenses. CLAO J. 13:1987;211-214.
27. Wilkinson, S. (1983). Composition and structure of lipopolysaccharides from, Pseudomonas aeruginosa. Rev. Infect. Dis. 5, S941.
28. Zaidi, T., Fleiszig, S., Preston, M., Goldberg, J. and Pier, G. (1996). Lipopolysaccharide outer core is a ligand for corneal cell binding and ingestion of Pseudomonas aeruginosa. Invest. Ophthalmol. Vis. Sci. 37, 976-86.
29. Zasloff M. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc. Natl. Acad. Sci. 84:1987;5449-5453.
30. Zhoa C., Wang I., Lehrer R. Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells. FEBS Lett. 396:1996;319-322.