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Volumn 11, Issue 5, 2000, Pages 1687-1696

Truncation mutants of the tight junction protein ZO-1 disrupt corneal epithelial cell morphology

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CELL MEMBRANE PROTEIN; CYTOKERATIN; MUTANT PROTEIN; VIMENTIN;

EID: 0034030506     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.11.5.1687     Document Type: Article
Times cited : (75)

References (42)
  • 1
    • 0028884033 scopus 로고
    • PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo
    • Alessi, D.R., Cuenda, A., Cohen, P., Dudley, D.T., and Saltiel, A.R. (1995). PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J. Biol. Chem. 270, 27489-27494.
    • (1995) J. Biol. Chem. , vol.270 , pp. 27489-27494
    • Alessi, D.R.1    Cuenda, A.2    Cohen, P.3    Dudley, D.T.4    Saltiel, A.R.5
  • 2
    • 0030113804 scopus 로고    scopus 로고
    • Cell signaling: MAGUK magic
    • Anderson, J.M. (1996). Cell signaling: MAGUK magic. Curr. Biol. 6, 382-384.
    • (1996) Curr. Biol. , vol.6 , pp. 382-384
    • Anderson, J.M.1
  • 4
    • 0028799226 scopus 로고
    • Tight junctions and the molecular basis for regulation of paracellular permeability
    • Anderson, J.M., and Van Itallie, C.M. (1995). Tight junctions and the molecular basis for regulation of paracellular permeability. Am. J. Physiol. 269, G467-G475.
    • (1995) Am. J. Physiol. , vol.269
    • Anderson, J.M.1    Van Itallie, C.M.2
  • 7
    • 0029799520 scopus 로고    scopus 로고
    • Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expres-sion of a mutant tight junction membrane protein
    • Balda, M.S., Whitney, J.A., Flores, C., Gonzalez, S., Cereijido, M., and Matter, K. (1996). Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expres-sion of a mutant tight junction membrane protein. J. Cell Biol. 134, 1031-1049.
    • (1996) J. Cell Biol. , vol.134 , pp. 1031-1049
    • Balda, M.S.1    Whitney, J.A.2    Flores, C.3    Gonzalez, S.4    Cereijido, M.5    Matter, K.6
  • 8
    • 0029908483 scopus 로고    scopus 로고
    • The tight junction protein ZO-2 consists of three PDZ domains and an alternatively spliced region
    • Beatch, M., Jesaitis, L.A., Gallin, W.J., Goodenough, D.A., and Stevenson, B.R. (1996). The tight junction protein ZO-2 consists of three PDZ domains and an alternatively spliced region. J. Biol. Chem. 271, 25723-25726.
    • (1996) J. Biol. Chem. , vol.271 , pp. 25723-25726
    • Beatch, M.1    Jesaitis, L.A.2    Gallin, W.J.3    Goodenough, D.A.4    Stevenson, B.R.5
  • 9
    • 0030748172 scopus 로고    scopus 로고
    • COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos
    • Chen, Y.H., Merzdorf, C., Paul, D.L., and Goodenough, D.A. (1997). COOH terminus of occludin is required for tight junction barrier function in early Xenopus embryos. J. Cell Biol. 138, 891-899.
    • (1997) J. Cell Biol. , vol.138 , pp. 891-899
    • Chen, Y.H.1    Merzdorf, C.2    Paul, D.L.3    Goodenough, D.A.4
  • 10
    • 0026492629 scopus 로고
    • The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein
    • Cho, K.O., Hunt, C.A., and Kennedy, M.B. (1992). The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9, 929-942.
    • (1992) Neuron , vol.9 , pp. 929-942
    • Cho, K.O.1    Hunt, C.A.2    Kennedy, M.B.3
  • 11
    • 0027207967 scopus 로고
    • The molecular organization of tight junctions
    • Citi, S. (1993). The molecular organization of tight junctions. J. Cell Biol. 121, 485-489.
    • (1993) J. Cell Biol. , vol.121 , pp. 485-489
    • Citi, S.1
  • 12
    • 0020693389 scopus 로고
    • Proteins of intermediate filaments. An immunohistochemical and biochemical approach to the classification of soft tissue tumors
    • Denk, H., Krepler, R., Artlieb, U., Gabbiani, G., Rungger-Brandle, E., Leoncini, P., and Franke, W.W. (1983). Proteins of intermediate filaments. An immunohistochemical and biochemical approach to the classification of soft tissue tumors. Am. J. Pathol. 110, 193-208.
    • (1983) Am. J. Pathol. , vol.110 , pp. 193-208
    • Denk, H.1    Krepler, R.2    Artlieb, U.3    Gabbiani, G.4    Rungger-Brandle, E.5    Leoncini, P.6    Franke, W.W.7
  • 13
    • 0031893838 scopus 로고    scopus 로고
    • Molecular structure and assembly of the tight junction
    • Denker, B.M., and Nigam, S.K. (1998). Molecular structure and assembly of the tight junction. Am. J. Physiol. 274, F1-F9.
    • (1998) Am. J. Physiol. , vol.274
    • Denker, B.M.1    Nigam, S.K.2
  • 14
    • 0032491391 scopus 로고    scopus 로고
    • The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton
    • Fanning, A.S., Jameson, B.J., Jesaitis, L.A., and Anderson, J.M. (1998). The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton. J. Biol. Chem. 273, 29745-29753.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29745-29753
    • Fanning, A.S.1    Jameson, B.J.2    Jesaitis, L.A.3    Anderson, J.M.4
  • 15
    • 0028828220 scopus 로고
    • Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes
    • Fujimoto, K. (1995). Freeze-fracture replica electron microscopy combined with SDS digestion for cytochemical labeling of integral membrane proteins. Application to the immunogold labeling of intercellular junctional complexes. J. Cell Sci. 108, 3443-3449.
    • (1995) J. Cell Sci. , vol.108 , pp. 3443-3449
    • Fujimoto, K.1
  • 16
    • 0030043414 scopus 로고    scopus 로고
    • Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures
    • Furuse, M., Fujimoto, K., Sato, N., Hirase, T., Tsukita, S., and Tsukita, S. (1996). Overexpression of occludin, a tight junction-associated integral membrane protein, induces the formation of intracellular multilamellar bodies bearing tight junction-like structures. J. Cell Sci. 109, 429-435.
    • (1996) J. Cell Sci. , vol.109 , pp. 429-435
    • Furuse, M.1    Fujimoto, K.2    Sato, N.3    Hirase, T.4    Tsukita, S.5    Tsukita, S.6
  • 17
    • 0032577975 scopus 로고    scopus 로고
    • Claudin-1 and -2: Novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin
    • Furuse, M., Fujita, K., Hiiragi, T., Fujimoto, K., and Tsukita, Sh. (1998a). Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J. Cell Biol. 141, 1539-1550.
    • (1998) J. Cell Biol. , vol.141 , pp. 1539-1550
    • Furuse, M.1    Fujita, K.2    Hiiragi, T.3    Fujimoto, K.4    Tsukita, Sh.5
  • 19
    • 0032547833 scopus 로고    scopus 로고
    • A single gene product, claudin-1 or -2 reconstitutes tight junction strands and recruits occludin in fibroblasts
    • Furuse, M., Sasaki, H., Fujimoto, K., and Tsukita, S. (1998b). A single gene product, claudin-1 or -2 reconstitutes tight junction strands and recruits occludin in fibroblasts. J. Cell Biol. 143, 391-401.
    • (1998) J. Cell Biol. , vol.143 , pp. 391-401
    • Furuse, M.1    Sasaki, H.2    Fujimoto, K.3    Tsukita, S.4
  • 21
    • 0032489875 scopus 로고    scopus 로고
    • ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin
    • Haskins, J., Gu, L., Wittchen, E.S., Hibbard, J., and Stevenson, B.R. (1998). ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin. J. Cell Biol. 141, 199-208.
    • (1998) J. Cell Biol. , vol.141 , pp. 199-208
    • Haskins, J.1    Gu, L.2    Wittchen, E.S.3    Hibbard, J.4    Stevenson, B.R.5
  • 22
    • 0026603087 scopus 로고
    • Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types
    • Howarth, A.G., Hughes, M.R., and Stevenson, B.R. (1992). Detection of the tight junction-associated protein ZO-1 in astrocytes and other nonepithelial cell types. Am. J. Physiol. 262, C461-C469.
    • (1992) Am. J. Physiol. , vol.262
    • Howarth, A.G.1    Hughes, M.R.2    Stevenson, B.R.3
  • 23
    • 0028221689 scopus 로고
    • Analysis of the distribution and phosphorylation state of ZO-1 in MDCK and nonepithelial cells
    • Howarth, A.G., Singer, K.L., and Stevenson, B.R. (1994). Analysis of the distribution and phosphorylation state of ZO-1 in MDCK and nonepithelial cells. J. Membr. Biol. 137, 261-270.
    • (1994) J. Membr. Biol. , vol.137 , pp. 261-270
    • Howarth, A.G.1    Singer, K.L.2    Stevenson, B.R.3
  • 24
    • 0030748548 scopus 로고    scopus 로고
    • Involvement of ZO-1 cadherin-based cell adhesion through its direct binding to α catenin and actin filaments
    • Itoh, M., Nagafuchi, A., Moroi, S., and Tsukita, S. (1997). Involvement of ZO-1 cadherin-based cell adhesion through its direct binding to α catenin and actin filaments. J. Cell Biol. 138, 181-192.
    • (1997) J. Cell Biol. , vol.138 , pp. 181-192
    • Itoh, M.1    Nagafuchi, A.2    Moroi, S.3    Tsukita, S.4
  • 25
    • 0025888954 scopus 로고
    • A 220-kD undercoat-constitutive protein: Its specific localization at cadherin-based cell-cell adhesion sites
    • Itoh, M., Yonemura, S., Nagafuchi, A., Tsukita, S., and Tsukita, S. (1991). A 220-kD undercoat-constitutive protein: Its specific localization at cadherin-based cell-cell adhesion sites. J. Cell Biol. 115, 1449-1462.
    • (1991) J. Cell Biol. , vol.115 , pp. 1449-1462
    • Itoh, M.1    Yonemura, S.2    Nagafuchi, A.3    Tsukita, S.4    Tsukita, S.5
  • 26
    • 0030953268 scopus 로고    scopus 로고
    • Transforming growth factor-β3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane
    • Kaartinen, V., Cui, X., Heisterkamp, N., Groffen, J., and Shuler, C.F. (1997). Transforming growth factor-β3 regulates transdifferentiation of medial edge epithelium during palatal fusion and associated degradation of the basement membrane. Dev. Dyn. 209, 255-260.
    • (1997) Dev. Dyn. , vol.209 , pp. 255-260
    • Kaartinen, V.1    Cui, X.2    Heisterkamp, N.3    Groffen, J.4    Shuler, C.F.5
  • 28
    • 0029143156 scopus 로고
    • Tight junctions, membrane-associated guanylate kinases and cell signaling
    • Kim, S. (1995). Tight junctions, membrane-associated guanylate kinases and cell signaling. Curr. Biol. 7, 641-649.
    • (1995) Curr. Biol. , vol.7 , pp. 641-649
    • Kim, S.1
  • 30
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll, R., Franke, W.W., Schiller, D.L., Geiger, B., and Krepler, R. (1982). The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31, 11-24.
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 31
    • 0033582334 scopus 로고    scopus 로고
    • Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands
    • Morita, K., Furuse, M., Fujimoto, K., and Tsukita, S. (1999). Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Proc. Natl. Acad. Sci. USA 96, 511-516.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 511-516
    • Morita, K.1    Furuse, M.2    Fujimoto, K.3    Tsukita, S.4
  • 32
    • 0026031310 scopus 로고
    • Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3
    • Potts, J.D., Dagle, J.M., Walder, J.A., Weeks, D.L., and Runyan, R.B. (1991). Epithelial-mesenchymal transformation of embryonic cardiac endothelial cells is inhibited by a modified antisense oligodeoxynucleotide to transforming growth factor beta 3. Proc. Natl. Acad. Sci. USA 88, 1516-1520.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1516-1520
    • Potts, J.D.1    Dagle, J.M.2    Walder, J.A.3    Weeks, D.L.4    Runyan, R.B.5
  • 33
    • 0027408247 scopus 로고
    • Identification of a ten-amino acid proline-rich SH3 binding site
    • Ren, R., Mayer, B.J., Cicchetti, P., and Baltimore, D. (1993). Identification of a ten-amino acid proline-rich SH3 binding site. Science 259, 1157-1161.
    • (1993) Science , vol.259 , pp. 1157-1161
    • Ren, R.1    Mayer, B.J.2    Cicchetti, P.3    Baltimore, D.4
  • 34
    • 0026623234 scopus 로고
    • TGF-beta 3-mediated tissue interaction during embryonic heart development
    • Runyan, R.B., Potts, J.D., and Weeks, D.L. (1992). TGF-beta 3-mediated tissue interaction during embryonic heart development. Mol. Reprod. Dev. 32, 152-159.
    • (1992) Mol. Reprod. Dev. , vol.32 , pp. 152-159
    • Runyan, R.B.1    Potts, J.D.2    Weeks, D.L.3
  • 35
    • 0031005659 scopus 로고    scopus 로고
    • The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
    • Savagner, P., Yamada, K.M., and Thiery, J.P. (1997). The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J. Cell Biol. 337, 1403-1419.
    • (1997) J. Cell Biol. , vol.337 , pp. 1403-1419
    • Savagner, P.1    Yamada, K.M.2    Thiery, J.P.3
  • 36
    • 0033516683 scopus 로고    scopus 로고
    • 2+ resorption
    • 2+ resorption. Science 285, 103-106.
    • (1999) Science , vol.285 , pp. 103-106
    • Simon, D.B.1
  • 38
    • 0023030826 scopus 로고
    • Identification of ZO-1: A high molecular weight polypeptide associated the tight junction (zonula occludens) in a variety of epithelia
    • Stevenson, B., Siliciano, J.D., Mooseker, M.S., and Goodenough, D.A. (1986). Identification of ZO-1: a high molecular weight polypeptide associated the tight junction (zonula occludens) in a variety of epithelia. J. Cell Biol. 103, 755-766.
    • (1986) J. Cell Biol. , vol.103 , pp. 755-766
    • Stevenson, B.1    Siliciano, J.D.2    Mooseker, M.S.3    Goodenough, D.A.4
  • 39
    • 0032440448 scopus 로고    scopus 로고
    • The tight junction: Morphology to molecules
    • Stevenson, B.R., and Keon, B.K. (1998). The tight junction: morphology to molecules. Annu. Rev. Cell Dev. Biol. 14, 89-109.
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , pp. 89-109
    • Stevenson, B.R.1    Keon, B.K.2
  • 40
    • 0031594269 scopus 로고    scopus 로고
    • TGFβ3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro
    • Sun, D., Vanderburg, C.R., Odierna, G.S., and Hay, E.D. (1998). TGFβ3 promotes transformation of chicken palate medial edge epithelium to mesenchyme in vitro. Development 325, 95-105.
    • (1998) Development , vol.325 , pp. 95-105
    • Sun, D.1    Vanderburg, C.R.2    Odierna, G.S.3    Hay, E.D.4
  • 41
    • 0027240084 scopus 로고
    • The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions
    • Willott, E., Balda, M.S., Fanning, A.S., Jameson, B., Van Itallie, C., and Anderson, J.M. (1993). The tight junction protein ZO-1 is homologous to the Drosophila discs-large tumor suppressor protein of septate junctions. Proc. Natl. Acad. Sci. USA 90, 7834-7838.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7834-7838
    • Willott, E.1    Balda, M.S.2    Fanning, A.S.3    Jameson, B.4    Van Itallie, C.5    Anderson, J.M.6
  • 42
    • 0031047483 scopus 로고    scopus 로고
    • A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier
    • Wong, V., and Gumbiner, B.A. (1997). A synthetic peptide corresponding to the extracellular domain of occludin perturbs the tight junction permeability barrier. J. Cell Biol. 136, 399-409.
    • (1997) J. Cell Biol. , vol.136 , pp. 399-409
    • Wong, V.1    Gumbiner, B.A.2


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