T-cell proliferation to superantigen-releasing Staphylococcus aureus by MHC class II-bearing keratinocytes under protection from bacterial cytolysin

Journal of Investigative Dermatology

Volumn 108, Issue 4, 1997, Pages 488-494

  Tokura, Yoshiki ^a   Furukawa, Fukumi ^a   Wakita, Hisashi ^a   Yagi, Hiroaki ^a   Ushijima, Tsutomu ^b   Takigawa, Masahiro ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

bacterial colonization; superantigens; T lymphocytes; toxin

Indexed keywords

CYTOLYSIN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MITOMYCIN C; STAPHYLOCOCCUS ALPHA TOXIN; SUPERANTIGEN;

ADULT; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HUMAN; HUMAN CELL; KERATINOCYTE; MALE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE;

EID: 0030932830     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12289728     Document Type: Article

References (41)

1. Aly R, Maibach HI, Shinefield HR: Microbial flora of atopic dermatitis. Arch Dermatol 113:780-782, 1977
2. Baker JJ, Tondreau SP: The stimulation of human peripheral blood lymphocytes by oral bacteria: macrophage and T-cell dependence. J Dent Res 64:906-912, 1985
3. Barrow GI, Feltham RKA: Cowan and Steel's Manual for the Identification of Medical Bacteria. 3rd ed. Cambridge University Press, New York, 1993
4. Basham TY, Nickoloff BJ, Merigan TC, Morhenn VB: Recombinant gamma interferon induced HLA-DR expression on cultured human keratinocytes. J Invest Dermatol 83:88-90, 1983
5. Bhakdi S, Füssle R, Utermann G, Tranum-Jensen J: Binding and partial inactivation of S. aureus α-toxin by human plasma low density lipoprotein. J Biol Chem 258:5899-5904, 1983
6. Bhakdi S, Muhly M, Korom S, Hugo F: Release of interleukin-1β associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes. Infect Immun 57:3512-3519, 1989
7. Bhakdi S, Tranum-Jensen J: Alpha-toxin of Staphylococcus aureus. Microbiol Rev 55:733-751, 1991
8. Braun MA, Gerlach D, Hartwig UF, Ozegowski JH, Romagne F, Carrel S, Köhler W, Fleischer: Stimulation of human T cells by streptococcal "superantigen" erythrogenic toxins (scarlet fever toxins). J Immunol 150:2457-2466, 1993
9. Chen VL, France DS, Martinelli GP: De novo synthesis of lysozyme by human epidermal cells. J Invest Dermatol 87:585-587, 1986
10. Dai R, Grammer SF, Streilein JW: Fresh and cultured Langerhans cells display differential capacities to activate hapten-specific T cells. J Immunol 150:59-66, 1993
11. Forwoll JM, Gebel HM, Rodey GE, Markham RB: In vitro responses of human T cells to Pseudomonas aeruginosa. Infect Immun 40:670-674, 1983
12. Fredriksson T, Pettersson U: Severe psoriasis: oral therapy with a new retinoid. Dermatologica, 157:238-244, 1978
13. Hanitin JM, Rajka G: Diagnostic features of atopic dermatitis. Acta Derm L'enereol (Stockholm) 92(suppl):44-47, 1990
14. Janeway CA Jr: Selective elements for the Vb region of the T cell receptor: Mls and the bacterial toxic mitogens. Adv Immunol 50:1-53, 1991
15. Julius M, Simpson E, Herzenberg LA: A rapid method for isolation of functional thymus-derived lymphocytes. Eur J Immunol 3:645-649, 1983
16. Kitajima Y, Inoue S, Yaoita M: Effects of pemphigus antibody on the regulation of cell-cell contact in keratinocyte cultures grown in low to normal Ca+ + concentration. J Invest Dermatol 89:167-171, 1987
17. Krieg AM, Yi A-K, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM: CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374:546-549, 1995
18. Kurnick JT, McCluskey RT, Bhan AK, Wright KA, Wilkinson R, Rubin RH: Escherichia coli-specific T lymphocytes in experimental pyelonephritis. J Immunol 141:3220-3226, 1988
19. Lester MR, Hofer MF, Gately M, Trumble A, Leung DYM: Down-regulating effects of IL-4 and IL-10 on the IFN-γ response in atopic dermatitis. J Immunol 154:6174-6181, 1995
20. Leung DYM, Walsh P, Giorno R, Norris DA: A potential role for superantigens in the pathogenesis of psoriasis. J Invest Dermatol 100:225-228, 1993
21. Lever R, Hadley K, Downey D, Mackie R: Staphylococcal colonization in atopic dermatitis and the effect of topical mupirocin therapy. Br J Dermatol 119:189-198, 1988
22. Leyden JJ, Marples RR, Kligman AM: Staphylococcus aureus in the lesions of atopic dermatitis. Br J Dermatol 90:525-530, 1974
23. MacFadden JP, Noble WC, Clamp RDR: Superantigenic exotoxin-secreting potential of Staphylococci isolated from atopic eczematous skin. Br J Dermatol 128:631-632, 1993
24. Marples RR, Heaton CL, Kligman AM: Staphylococcus aureus in psoriasis. Arch Dermatol 107;568-570, 1973
25. Marrack P, Kappler J: The Staphylococcal enterotoxins and their relatives. Science 248;705-711, 1990
26. Marrack P, Kappler JW: Subversion of the immune system by pathogens. Cell 76:323-332, 1994
27. Müller-Alouf H, Alouf JE, Gerlach D, Ozegowski J-H, Fitting C, Cacaillon J-M: Comparative study of cytokine release by human peripheral blood mononuclear cells stimulated with Streptococcus pyogenes superantigenic erythrogenic toxins, heat-killed streptococci, and lipopolysaccharide. Infect Immun 62:4915-4921, 1994
28. Nickoloff BJ, Mitra RS, Green J, Zheng XG, Shimizu Y, Thompson C, Turka LA: Accessory cell function of keratinocytes for superantigens: dependence on lymphocyte function-associated antigen- 1/intercellular adhesion molecule-1 interaction. J Immunol 150:2148-59, 1993
29. Ogawa H, Miyasaki H: Immunochemical studies on the human skin lysozyme. J Invest Dermatol 58:59-62, 1972
30. Redfield RJ: Evolution of natural transformation: testing the DNA repair hypothesis in Bacillus subtilis and Haemophilus influenzae. Genetics 133:755-761, 1993
31. Strange P, Skov L, Baadsgaard O: Interferon gamma-treated keratinocytes activate T cells in the presence of superantigens: involvement of major histocompatibility complex class II molecules. J Invest Dermatol 102:150-154, 1994
32. Strange P, Slov L, Lisby S, Nielsen PL, Baadsgaad O: Staphylococcal enterotoxin B applied on intact normal and intact atopic skin induces dermatitis. Arch Dermatol 132:27-33, 1996
33. Tarkkanen J, Saksela H, Lanier LL: Bacterial activation of human natural killer cells. Characteristics of the activation process and identification of the effector cell. J Immunol 137:2428-2433, 1986
34. Tokura Y, Heald PW, Yan SL, Edelson RL: Stimulation of cutaneous T-cell lymphoma cells with superantigenic Staphylococcal toxins. J Invest Dermatol 98:33-37, 1992
35. Tokura Y, Yagi J, O'Malley M, Lewis JM, Takigawa M, Edelson RL, Tigelaar RE: Superantigenic staphylococcal exotoxins induce T-cell proliferation in the presence of Langerhans cells or class II-bearing keratinocytes and stimulate keratinocytes to produce T-cell-activating cytokines. J Invest Dermatol 102:31-38, 1994a
36. Tokura Y, Yagi H, Hashizume H, Yagi J, Furukawa F, Takigawa M: Accessory cell ability of Langerhans cells for superantigen is resistant to ultraviolet-B light. Photochem Photobiol 60;147-153, 1994b
37. Tokura Y, Yagi H, Ohshima A, Kurokawa S, Wakita H, Yokote R, Shirahama S, Furukawa F, Takigawa M: Cutaneous colonization of Staphylococci influences the disease activity of Sezary syndrome: A potential role for bacterial superantigens. Br J Dermatol 133:6-12, 1995
38. Wakita H, Tokura Y, Furukawa F, Takigawa M: Staphylococcal enterotoxin B upregulates expression of ICAM-1 molecules on IFN-γ-treated keratinocytes and keratinocytes cell lines. J Invest Dermatol 105:536-542, 1995
39. Walev I, Martin E, Jonas D, Mohamadzadeh M, Müller-Klieser W, Kunz L, Bhakdi S: Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions. Infect Immun 61:4972-4979, 1993
40. Yagi J, Baron J, Buxser S, Janeway C Jr: Bacterial proteins that mediate the association of a defined subset of T cell receptor: CD4 complexes with class II MHC. J Immunol 144:892-901, 1990
41. Yokote R, Tokura Y, Furukawa F, Takigawa M: Susceptible responsiveness to bacterial superantigens in peripheral blood mononuclear cells from patients with psoriasis. Arch Dermatol Res 287:443-447, 1995