Deletion of the triplet repeat encoding polyglutamine within the mouse Huntington's disease gene results in subtle behavioral/motor phenotypes in vivo and elevated levels of ATP with cellular senescence in vitro

Human Molecular Genetics

Volumn 15, Issue 4, 2006, Pages 607-623

  Clabough, Erin B D ^a   Zeitlin, Scott O ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; HUNTINGTIN; POLYGLUTAMINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL AGING; CELL CULTURE; CONTROLLED STUDY; EMBRYO DEVELOPMENT; FIBROBLAST; GENE DELETION; GENE FREQUENCY; HISTOPATHOLOGY; HOMEOSTASIS; HUNTINGTON CHOREA; IN VITRO STUDY; IN VIVO STUDY; MAZE TEST; MOTOR COORDINATION; MOUSE; NONHUMAN; NUCLEOTIDE REPEAT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; WILD TYPE;

ADENOSINE TRIPHOSPHATE; ANIMALS; BASE SEQUENCE; BEHAVIOR, ANIMAL; CELL AGING; CELLS, CULTURED; EMBRYO; ENERGY METABOLISM; FIBROBLASTS; HUMANS; MAZE LEARNING; MICE; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; SEQUENCE DELETION; TRINUCLEOTIDE REPEATS;

ANIMALIA;

EID: 32144455692     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddi477     Document Type: Article

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