Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence

Biochemical Journal

Volumn 376, Issue 2, 2003, Pages 403-411

  Zwerschke, Werner ^a,b   Mazurek, Sybille ^c   Stöckl, Petra ^a   Hütter, Eveline ^a   Eigenbrodt, Erich ^b   Jansen Dürr, Pidder ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

^b TYROLEAN CANCER RESEARCH INSTITUTE   (Austria)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

AMP; Fibroblast; Glycolysis; Metabolism; Senescence; Tumour suppression

Indexed keywords

ADENOSINETRIPHOSPHATE; CARBOHYDRATES; CELLS; CHEMICAL ACTIVATION; ONCOLOGY; OXYGEN; TUMORS;

CELLULAR SENESCENCES;

HUMAN ENGINEERING;

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CARBOHYDRATE; CYCLIN DEPENDENT KINASE INHIBITOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GLYCOLYTIC ENZYME; HYDROGEN; NUCLEOTIDE; PYRUVATE KINASE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CANCER INHIBITION; CARBOHYDRATE METABOLISM; CELL PROLIFERATION; ENZYME ACTIVITY; FIBROBLAST; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; ONCOGENE RAS; PRIORITY JOURNAL; SENESCENCE; UPREGULATION;

ADENOSINE MONOPHOSPHATE; CELL AGING; CELL DIVISION; CELLS, CULTURED; FIBROBLASTS; GLYCOLYSIS; HUMANS; ION TRANSPORT; PROTONS; RIBONUCLEOTIDES;

ANIMALIA; MAMMALIA;

EID: 0346256784     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030816     Document Type: Article

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