Genomic characterization of the lysophosphatidic acid receptor gene, Lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA

Genomics

Volumn 64, Issue 2, 2000, Pages 155-169

  Contos, James J A ^a   Chun, Jerold ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; COMPLEMENTARY DNA; LYSOPHOSPHATIDIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME 19P; DISEASE ASSOCIATION; DNA DETERMINATION; EXON; FRAMESHIFT MUTATION; GENE LOCATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; RNA SPLICING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; TUMOR;

RODENTIA;

EID: 0034162958     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2000.6122     Document Type: Article

References (48)

1. Abood M. E., Ditto K. E., Noel M. A., Showalter V. M., Tao Q. Isolation and expression of a mouse CB1 cannabinoid receptor gene. Comparison of binding properties with those of native CB1 receptors in mouse brain and N18TG2 neuroblastoma cells. Biochem. Pharmacol. 53:1997;207-214.
2. Altschul S. F., Gish W., Miller W., Myers E. W., Lipman D. J. Basic local alignment search tool. J. Mol. Biol. 215:1990;403-410.
3. Amano M., Ito M., Kimura K., Fukata Y., Chihara K., Nakano T., Matsuura Y., Kaibuchi K. Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase). J. Biol. Chem. 271:1996;20246-20249.
4. An S., Bleu T., Hallmark O. G., Goetzl E. J. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid. J. Biol. Chem. 273:1998;7906-7910.
5. An S., Bleu T., Huang W., Hallmark O. G., Coughlin S. R., Goetzl E. J. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids. FEBS Lett. 417:1997;279-282.
6. Ausubel F. M., Brent R., Kingston R. E., Moore D. D., Seidman J. G., Smith J. A., Struhl K. Current Protocols in Molecular Biology. 1994;Wiley, New York.
7. Bahler M., Kehrer I., Gordon L., Stoffler H. E., Olsen A. S. Physical mapping of human myosin-IXB (MYO9B), the human orthologue of the rat myosin myr 5, to chromosome 19p13.1. Genomics. 43:1997;107-109.
8. Birnstiel M. L., Busslinger M., Strub K. Transcription termination and 3′ processing: The end is in site. Cell. 41:1985;349-359.
9. Chun J., Contos J., Munroe D. A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs). Cell. Biochem. Biophys. 30:1999;213-242.
10. Contos J. J., Chun J. Complete cDNA sequence, genomic structure, and chromosomal localization of the LPA receptor gene, lpA1/vzg-1/Gpcr26. Genomics. 51:1998;364-378.
11. Durieux M. E. Lysophosphatidate Signaling: Cellular Effects and Molecular Mechanisms. 1995;Landes, Austin.
12. Felder C. C., Briley E. M., Axelrod J., Simpson J. T., Mackie K., Devane W. A. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sci. USA. 90:1993;7656-7660.
13. Fernhout B. J., Dijcks F. A., Moolenaar W. H., Ruigt G. S. Lysophosphatidic acid induces inward currents in Xenopus laevis oocytes: Evidence for an extracellular site of action. Eur. J. Pharmacol. 213:1992;313-315.
14. Freedman N. J., Lefkowitz R. J. Desensitization of G protein-coupled receptors. Rec. Prog. Horm. Res. 51:1996;319-353.
15. Fukushima N., Kimura Y., Chun J. A single receptor encoded by vzg-1/lpA1/edg-2 couples to G-proteins and mediates multiple cellular responses to lysophosphatidic acid (LPA). Proc. Natl. Acad. Sci. USA. 95:1998;6151-6156.
16. Hecht J. H., Weiner J. A., Post S. R., Chun J. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell. Biol. 135:1996;1071-1083.
17. Huret J. L., Brizard A., Slater R., Charrin C., Bertheas M. F., Guilhot F., Hahlen K., Kroes W., van Leeuwen E., Schoot E. V., Beishuizen A., Tanzer J., Hagemeijer A. Cytogenetic heterogeneity in t(11;19) acute leukemia: Clinical, hematological and cytogenetic analyses of 48 patients - Updated published cases and 16 new observations. Leukemia. 7:1993;152-160.
18. Imamura F., Horai T., Mukai M., Shinkai M., Sawada M., Adkedo H. Induction of in vitro tumor cell invasion of cellular monolayers by lysophosphatidic acid or phospholipase D. Biochem. Biophys. Res. Commun. 193:1993;497-503.
19. Janaswami P. M., Birkenmeier E. H., Cook S. A., Rowe L. B., Bronson R. T., Davisson M. T. Identification and genetic mapping of a new polycystic kidney disease on mouse chromosome 8. Genomics. 40:1997;101-107.
20. Kamps M. P., Murre C., Sun X. H., Baltimore D. A new homeobox gene contributes the DNA binding domain of the t(1;19) translocation protein in pre-B ALL. Cell. 60:1990;547-555.
21. Lane P. W., Beamer T. C., Myers D. D. Myodystrophy, a new myopathy on chromosome 8 of the mouse. J. Hered. 67:1976;135-138.
22. Lee M. J., Van Brocklyn J. R., Thangada S., Liu C. H., Hand A. R., Menzeleev R., Spiegel S., Hla T. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science. 279:1998;1552-1555.
23. Liu C. H., Hla T. The mouse gene for the inducible G-protein-coupled receptor edg-1. Genomics. 43:1997;15-24.
24. Marchuk D., Drumm M., Saulino A., Collins F. S. Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products. Nucleic Acids Res. 19:1991;1154.
25. Mills K. A., Mathews K. D., Scherpbier-Heddema T., Schelper R. L., Schmalzel R., Bailey H. L., Nadeau J. H., Buetow K. H., Murray J. C. Genetic mapping near the myd locus on mouse chromosome 8. Mamm. Genome. 6:1995;278-280.
26. Moolenaar W. H., Kranenburg O., Postma F. R., Zondag G. C. Lysophosphatidic acid: G-protein signalling and cellular responses. Curr. Opin. Cell Biol. 9:1997;168-173.
27. Peltenburg L. T., Murre C. Engrailed and Hox homeodomain proteins contain a related Pbx interaction motif that recognizes a common structure present in Pbx. EMBO J. 15:1996;3385-3393.
28. Peltenburg L. T., Murre C. Specific residues in the Pbx homeodomain differentially modulate the DNA-binding activity of Hox and Engrailed proteins. Development. 124:1997;1089-1098.
29. Perlick H. A., Medghalchi S. M., Spencer F. A., Kendzior R. J. Jr., Dietz H. C. Mammalian orthologues of a yeast regulator of nonsense transcript stability. Proc. Natl. Acad. Sci. USA. 93:1996;10928-10932.
30. Phelan M. L., Rambaldi I., Featherstone M. S. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol. Cell. Biol. 15:1995;3989-3997.
31. Post P. L., Bokoch G. M., Mooseker M. S. Human myosin-IXb is a mechanochemically active motor and a GAP for rho. J. Cell. Sci. 111:1998;941-950.
32. Powell A. J., Gates P. B., Wylie D., Velloso C. P., Brockes J. P., Jat P. S. Immortalization of rat embryo fibroblasts by a 3′-untranslated region. Exp. Cell Res. 240:1998;252-262.
33. Raff T., van der Giet M., Endemann D., Wiederholt T., Paul M. Design and testing of beta-actin primers for RT-PCR that do not co-amplify processed pseudogenes. BioTechniques. 23:1997;456-460.
34. Rauch U., Grimpe B., Kulbe G., Arnold-Ammer I., Beier D. R., Fassler R. Structure and chromosomal localization of the mouse neurocan gene. Genomics. 28:1995;405-410.
35. Ridley A. J., Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell. 70:1992;389-399.
36. Rimokh R., Berger F., Bastard C., Klein B., French M., Archimbaud E., Rouault J. P., Santa Lucia B., Duret L., Vuillaume M. Rearrangement of CCND1 (BCL1/PRAD1) 3′ untranslated region in mantle-cell lymphomas and t(11q13)-associated leukemias. Blood. 83:1994;3689-3696.
37. Rowe L. B., Nadeau J. H., Turner R., Frankel W. N., Letts V. A., Eppig J. T., Ko M. S., Thurston S. J., Birkenmeier E. H. Maps from two interspecific backcross DNA panels available as a community genetic mapping resource. Mamm. Genome. 5:1994;253-274.
38. Sanger F., Nicklen S., Coulson A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
39. Smit A. F. The origin of interspersed repeats in the human genome. Curr. Opin. Genet. Dev. 6:1996;743-748.
40. Stam J. C., Michiels F., van der Kammen R. A., Moolenaar W. H., Collard J. G. Invasion of T-lymphoma cells: Cooperation between Rho family GTPases and lysophospholipid receptor signaling. EMBO J. 17:1998;4066-4074.
41. Stella N., Schweitzer P., Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 388:1997;773-778.
42. van Corven E. J., Groenink A., Jalink K., Eichholtz T., Moolenaar W. H. Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins. Cell. 59:1989;45-54.
43. van Dijk M. A., Peltenburg L. T., Murre C. Hox gene products modulate the DNA binding activity of Pbx1 and Pbx2. Mech. Dev. 52:1995;99-108.
44. Wahle E. Poly(A) tail length control is caused by termination of processive synthesis. J. Biol. Chem. 270:1995;2800-2808.
45. Xu Y., Fang X. J., Casey G., Mills G. B. Lysophospholipids activate ovarian and breast cancer cells. Biochem. J. 309:1995;933-940.
46. Xu Y., Shen Z., Wiper D. W., Wu M., Morton R. E., Elson P., Kennedy A. W., Belinson J., Markman M., Casey G. Lysophosphatidic acid as a potential biomarker for ovarian and other gynecologic cancers. J. Am. Med. Assoc. 280:1998;719-723.
47. Zhang G., Contos J. J., Weiner J. A., Fukushima N., Chun J. Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate. Gene. 227:1999;89-99.
48. Zondag G. C., Postma F. R., Etten I. V., Verlaan I., Moolenaar W. H. Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1. Biochem. J. 330:1998;605-609.