메뉴 건너뛰기




Volumn 10, Issue 7, 2004, Pages 712-718

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDIC ACID; PROTEIN KINASE C GAMMA; RHO KINASE;

EID: 3142685946     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1060     Document Type: Article
Times cited : (460)

References (46)
  • 2
    • 0033526651 scopus 로고    scopus 로고
    • Neuropathic pain: Aetiology, symptoms, mechanisms, and management
    • Woolf, C.J. & Mannion, R.J. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet 353, 1959-1964 (1999).
    • (1999) Lancet , vol.353 , pp. 1959-1964
    • Woolf, C.J.1    Mannion, R.J.2
  • 3
    • 0034578946 scopus 로고    scopus 로고
    • Possible role of inflammatory mediators in tactile hypersensitivity in rat models of mononeuropathy
    • Cui, J.G., Holmin, S., Mathiesen, T., Meyerson, B.A. & Linderoth, B. Possible role of inflammatory mediators in tactile hypersensitivity in rat models of mononeuropathy. Pain 88, 239-248 (2000).
    • (2000) Pain , vol.88 , pp. 239-248
    • Cui, J.G.1    Holmin, S.2    Mathiesen, T.3    Meyerson, B.A.4    Linderoth, B.5
  • 4
    • 0032536413 scopus 로고    scopus 로고
    • Painful mononeuropathy in C57BL/Wld mice with delayed wallerian degeneration: Differential effects of cytokine production and nerve regeneration on thermal and mechanical hypersensitivity
    • Sommer, C. & Schafers, M. Painful mononeuropathy in C57BL/Wld mice with delayed wallerian degeneration: differential effects of cytokine production and nerve regeneration on thermal and mechanical hypersensitivity. Brain Res. 784, 154-162 (1998).
    • (1998) Brain Res. , vol.784 , pp. 154-162
    • Sommer, C.1    Schafers, M.2
  • 6
    • 0033529298 scopus 로고    scopus 로고
    • Does a neuroimmune interaction contribute to the genesis of painful peripheral neuropathies?
    • Bennett, G.J. Does a neuroimmune interaction contribute to the genesis of painful peripheral neuropathies? Proc. Natl. Acad. Sci. USA 96, 7737-7738 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7737-7738
    • Bennett, G.J.1
  • 7
    • 0036458019 scopus 로고    scopus 로고
    • Morphological and pharmacological evidence for the role of peripheral prostaglandins in the pathogenesis of neuropathic pain
    • Ma, W. & Eisenach, J.C. Morphological and pharmacological evidence for the role of peripheral prostaglandins in the pathogenesis of neuropathic pain. Eur. J. Neurosci. 15, 1037-1047 (2002).
    • (2002) Eur. J. Neurosci. , vol.15 , pp. 1037-1047
    • Ma, W.1    Eisenach, J.C.2
  • 8
    • 0033176025 scopus 로고    scopus 로고
    • Causes and consequences of sympathetic basket formation in dorsal root ganglia
    • Ramer, M.S., Thompson, S.W. & McMahon, S.B. Causes and consequences of sympathetic basket formation in dorsal root ganglia. Pain 6 (Suppl.), S111-S120 (1999).
    • (1999) Pain , vol.6 , Issue.SUPPL.
    • Ramer, M.S.1    Thompson, S.W.2    McMahon, S.B.3
  • 9
    • 0018693441 scopus 로고
    • Platelet aggregation evoked in vitro and in vivo by phosphatidic acids and lysoderivatives: Identity with substances in aged serum (DAS)
    • Schumacher, K.A., Classen, H.G. & Spath, M. Platelet aggregation evoked in vitro and in vivo by phosphatidic acids and lysoderivatives: identity with substances in aged serum (DAS). Thromb. Haemost. 42, 631-640 (1979).
    • (1979) Thromb. Haemost. , vol.42 , pp. 631-640
    • Schumacher, K.A.1    Classen, H.G.2    Spath, M.3
  • 10
    • 0027232391 scopus 로고
    • The bioactive phospholipid lysophosphatidic acid is released from activated platelets
    • Eichholtz, T., Jalink, K., Fahrenfort, I. & Moolenaar, W.H. The bioactive phospholipid lysophosphatidic acid is released from activated platelets. Biochem. J. 291, 677-680 (1993).
    • (1993) Biochem. J. , vol.291 , pp. 677-680
    • Eichholtz, T.1    Jalink, K.2    Fahrenfort, I.3    Moolenaar, W.H.4
  • 13
    • 0032518824 scopus 로고    scopus 로고
    • Serum-induced changes in the physiology of mammalian retinal glial cells: Role of lysophosphatidic acid
    • Kusaka, S., Kapousta-Bruneau, N., Green, D.G. & Puro, D.G. Serum-induced changes in the physiology of mammalian retinal glial cells: role of lysophosphatidic acid. J. Physiol. 506, 445-458 (1998).
    • (1998) J. Physiol. , vol.506 , pp. 445-458
    • Kusaka, S.1    Kapousta-Bruneau, N.2    Green, D.G.3    Puro, D.G.4
  • 14
    • 0037016145 scopus 로고    scopus 로고
    • Lysophosphatidic acid in neural signaling
    • Ye, X., Fukushima, N., Kingsbury, M.A. & Chun, J. Lysophosphatidic acid in neural signaling. Neuroreport 13, 2169-2175 (2002).
    • (2002) Neuroreport , vol.13 , pp. 2169-2175
    • Ye, X.1    Fukushima, N.2    Kingsbury, M.A.3    Chun, J.4
  • 15
    • 0036892749 scopus 로고    scopus 로고
    • Neurobiology of lysophosphatidic acid signaling
    • Fukushima, N., Ye, X. & Chun, J. Neurobiology of lysophosphatidic acid signaling. Neuroscientist 8, 540-550 (2002).
    • (2002) Neuroscientist , vol.8 , pp. 540-550
    • Fukushima, N.1    Ye, X.2    Chun, J.3
  • 16
    • 0344011597 scopus 로고    scopus 로고
    • Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
    • Kingsbury, M.A., Rehen, S.K., Contos, J.J., Higgins, C.M. & Chun, J. Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding. Nat. Neurosci. 6, 1292-1299 (2003).
    • (2003) Nat. Neurosci. , vol.6 , pp. 1292-1299
    • Kingsbury, M.A.1    Rehen, S.K.2    Contos, J.J.3    Higgins, C.M.4    Chun, J.5
  • 17
    • 0033788829 scopus 로고    scopus 로고
    • Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system
    • Ishii, I., Contos, J.J., Fukushima, N. & Chun, J. Functional comparisons of the lysophosphatidic acid receptors, LP(A1)/VZG-1/EDG-2, LP(A2)/EDG-4, and LP(A3)/EDG-7 in neuronal cell lines using a retrovirus expression system. Mol. Pharmacol. 58, 895-902 (2000).
    • (2000) Mol. Pharmacol. , vol.58 , pp. 895-902
    • Ishii, I.1    Contos, J.J.2    Fukushima, N.3    Chun, J.4
  • 18
    • 0344417883 scopus 로고    scopus 로고
    • Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice
    • Renback, K., Inoue, M. & Ueda, H. Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice. Neurosci. Lett. 270, 59-61 (1999).
    • (1999) Neurosci. Lett. , vol.270 , pp. 59-61
    • Renback, K.1    Inoue, M.2    Ueda, H.3
  • 19
    • 0033955969 scopus 로고    scopus 로고
    • Vzg-1/lysophosphatidic acid-receptor involved in peripheral pain transmission
    • Renback, K., Inoue, M., Yoshida, A., Nyberg, F. & Ueda, H. Vzg-1/lysophosphatidic acid-receptor involved in peripheral pain transmission. Brain Res. Mol. Brain Res. 75, 350-354 (2000).
    • (2000) Brain Res. Mol. Brain Res. , vol.75 , pp. 350-354
    • Renback, K.1    Inoue, M.2    Yoshida, A.3    Nyberg, F.4    Ueda, H.5
  • 20
    • 0029836932 scopus 로고    scopus 로고
    • Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
    • Hecht, J.H., Weiner, J.A., Post, S.R. & Chun, J. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex. J. Cell. Biol. 135, 1071-1083 (1996).
    • (1996) J. Cell. Biol. , vol.135 , pp. 1071-1083
    • Hecht, J.H.1    Weiner, J.A.2    Post, S.R.3    Chun, J.4
  • 21
    • 0032568613 scopus 로고    scopus 로고
    • A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid
    • Fukushima, N., Kimura, Y. & Chun, J. A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid. Proc. Natl. Acad. Sci. USA 95, 6151-6156 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6151-6156
    • Fukushima, N.1    Kimura, Y.2    Chun, J.3
  • 22
    • 0033938777 scopus 로고    scopus 로고
    • Botulinum toxin C3 inhibits hyperalgesia in mice with partial sciatic nerve injury
    • Ye, X., Inoue, M. & Ueda, H. Botulinum toxin C3 inhibits hyperalgesia in mice with partial sciatic nerve injury. Jpn. J. Pharmacol. 83, 161-163 (2000).
    • (2000) Jpn. J. Pharmacol. , vol.83 , pp. 161-163
    • Ye, X.1    Inoue, M.2    Ueda, H.3
  • 23
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata, M. et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389, 990-994 (1997).
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1
  • 24
    • 0033609118 scopus 로고    scopus 로고
    • Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid
    • Weiner, J.A. & Chun, J. Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid. Proc. Natl. Acad. Sci. USA 96, 5233-5238 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5233-5238
    • Weiner, J.A.1    Chun, J.2
  • 25
    • 0032897697 scopus 로고    scopus 로고
    • In vivo molecular signal transduction of peripheral mechanisms of pain
    • Ueda, H. In vivo molecular signal transduction of peripheral mechanisms of pain. Jpn. J. Pharmacol. 79, 263-268 (1999).
    • (1999) Jpn. J. Pharmacol. , vol.79 , pp. 263-268
    • Ueda, H.1
  • 26
    • 0037373066 scopus 로고    scopus 로고
    • Novel expression of vanilloid receptor 1 on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain
    • Rashid, M.H. et al. Novel expression of vanilloid receptor 1 on capsaicin-insensitive fibers accounts for the analgesic effect of capsaicin cream in neuropathic pain. J. Pharmacol. Exp. Ther. 304, 940-948 (2003).
    • (2003) J. Pharmacol. Exp. Ther. , vol.304 , pp. 940-948
    • Rashid, M.H.1
  • 27
    • 0031775956 scopus 로고    scopus 로고
    • Partial sciatic nerve injury in the mouse as a model of neuropathic pain: Behavioral and neuroanatomical correlates
    • Malmberg, A.B. & Basbaum, A.I. Partial sciatic nerve injury in the mouse as a model of neuropathic pain: behavioral and neuroanatomical correlates. Pain 76, 215-222 (1998).
    • (1998) Pain , vol.76 , pp. 215-222
    • Malmberg, A.B.1    Basbaum, A.I.2
  • 28
    • 0030881680 scopus 로고    scopus 로고
    • Preserved acute pain and reduced neuropathic pain in mice lacking PKCγ
    • Malmberg, A.B., Chen, C., Tonegawa, S. & Basbaum, A.I. Preserved acute pain and reduced neuropathic pain in mice lacking PKCγ. Science 278, 279-283 (1997).
    • (1997) Science , vol.278 , pp. 279-283
    • Malmberg, A.B.1    Chen, C.2    Tonegawa, S.3    Basbaum, A.I.4
  • 29
    • 0035869568 scopus 로고    scopus 로고
    • Upregulation of dorsal root ganglion α2δ calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats
    • Luo, Z.D. et al. Upregulation of dorsal root ganglion α2δ calcium channel subunit and its correlation with allodynia in spinal nerve-injured rats. J. Neurosci. 21, 1868-1875 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 1868-1875
    • Luo, Z.D.1
  • 30
    • 0036897329 scopus 로고    scopus 로고
    • Injury type-specific calcium channel α2 δ-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin
    • Luo, Z.D. et al. Injury type-specific calcium channel α2 δ-1 subunit up-regulation in rat neuropathic pain models correlates with antiallodynic effects of gabapentin. J. Pharmacol. Exp. Ther. 303, 1199-1205 (2002).
    • (2002) J. Pharmacol. Exp. Ther. , vol.303 , pp. 1199-1205
    • Luo, Z.D.1
  • 31
    • 0035884770 scopus 로고    scopus 로고
    • Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling
    • Weiner, J.A., Fukushima, N., Contos, J.J., Scherer, S.S. & Chun, J. Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling. J. Neurosci. 21, 7069-7078 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 7069-7078
    • Weiner, J.A.1    Fukushima, N.2    Contos, J.J.3    Scherer, S.S.4    Chun, J.5
  • 32
    • 0032836436 scopus 로고    scopus 로고
    • Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22
    • Brancolini, C. et al. Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22. Mol. Biol. Cell 10, 2441-2459 (1999).
    • (1999) Mol. Biol. Cell , vol.10 , pp. 2441-2459
    • Brancolini, C.1
  • 33
    • 0028116805 scopus 로고
    • Pain in the Guillain-Barre syndrome: A clinical review
    • Pentland, B. & Donald, S.M. Pain in the Guillain-Barre syndrome: a clinical review. Pain 59, 159-164 (1994).
    • (1994) Pain , vol.59 , pp. 159-164
    • Pentland, B.1    Donald, S.M.2
  • 34
    • 0031648807 scopus 로고    scopus 로고
    • Neuropathic pain in Charcot-Marie-Tooth disease
    • Carter, G.T. et al. Neuropathic pain in Charcot-Marie-Tooth disease. Arch. Phys. Med. Rehabil. 79, 1560-1564 (1998).
    • (1998) Arch. Phys. Med. Rehabil. , vol.79 , pp. 1560-1564
    • Carter, G.T.1
  • 35
    • 0033681225 scopus 로고    scopus 로고
    • Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice
    • Gillespie, C.S. et al. Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice. Neuron 26, 523-531 (2000).
    • (2000) Neuron , vol.26 , pp. 523-531
    • Gillespie, C.S.1
  • 36
    • 0043131153 scopus 로고    scopus 로고
    • Neuropeptides - An overview
    • Hokfelt, T. et al. Neuropeptides-an overview. Neuropharmacology 39, 1337-1356 (2000).
    • (2000) Neuropharmacology , vol.39 , pp. 1337-1356
    • Hokfelt, T.1
  • 38
    • 9244235478 scopus 로고    scopus 로고
    • Possible role of protein kinase C in the sensitization of primate spinothalamic tract neurons
    • Lin, Q., Peng, Y.B. & Willis, W.D. Possible role of protein kinase C in the sensitization of primate spinothalamic tract neurons. J. Neurosci. 16, 3026-3034 (1996).
    • (1996) J. Neurosci. , vol.16 , pp. 3026-3034
    • Lin, Q.1    Peng, Y.B.2    Willis, W.D.3
  • 39
    • 0035038778 scopus 로고    scopus 로고
    • Role of neurotransmitters in sensitization of pain responses
    • Willis, W.D. Role of neurotransmitters in sensitization of pain responses. Ann. NY Acad. Sci. 933, 142-156 (2001).
    • (2001) Ann. NY Acad. Sci. , vol.933 , pp. 142-156
    • Willis, W.D.1
  • 40
    • 0028885829 scopus 로고
    • Increases in protein kinase C γ immumoreactivity in the spinal cord dorsal horn of rats with painful mononeuropathy
    • Mao, J., Price, D.D., Phillips, L.L., Lu, J. & Mayer, D.J. Increases in protein kinase C γ immumoreactivity in the spinal cord dorsal horn of rats with painful mononeuropathy. Neurosci. Lett. 198, 75-78 (1995).
    • (1995) Neurosci. Lett. , vol.198 , pp. 75-78
    • Mao, J.1    Price, D.D.2    Phillips, L.L.3    Lu, J.4    Mayer, D.J.5
  • 41
    • 0034698508 scopus 로고    scopus 로고
    • Loose ligation of the rat sciatic nerve is accompanied by changes in the subcellular content of protein kinase C β II and γ in the spinal dorsal horn
    • Miletic, V., Bowen, K.K. & Miletic, G. Loose ligation of the rat sciatic nerve is accompanied by changes in the subcellular content of protein kinase C β II and γ in the spinal dorsal horn. Neurosci. Lett. 288, 199-202 (2000).
    • (2000) Neurosci. Lett. , vol.288 , pp. 199-202
    • Miletic, V.1    Bowen, K.K.2    Miletic, G.3
  • 42
    • 0034700050 scopus 로고    scopus 로고
    • Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior
    • Contos, J.J., Fukushima, N., Weiner, J.A., Kaushal, D. & Chun, J. Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Proc. Natl. Acad. Sci. USA 97, 13384-13389 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 13384-13389
    • Contos, J.J.1    Fukushima, N.2    Weiner, J.A.3    Kaushal, D.4    Chun, J.5
  • 43
    • 0036786445 scopus 로고    scopus 로고
    • Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Eg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)
    • Contos, J.J. et al. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Eg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol. Cell. Biol. 22, 6921-6929 (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6921-6929
    • Contos, J.J.1
  • 44
    • 0020525719 scopus 로고
    • Ethical guidelines for investigations of experimental pain in conscious animals
    • Zimmermann, M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16, 109-110 (1983).
    • (1983) Pain , vol.16 , pp. 109-110
    • Zimmermann, M.1
  • 45
    • 0030994297 scopus 로고    scopus 로고
    • Heterozygous peripheral myelin protein 22-deficient mice are affected by a progressive demyelinating tomaculous neuropathy
    • Adlkofer, K. et al. Heterozygous peripheral myelin protein 22-deficient mice are affected by a progressive demyelinating tomaculous neuropathy. J. Neurosci. 17, 4662-4671 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 4662-4671
    • Adlkofer, K.1
  • 46
    • 0037405722 scopus 로고    scopus 로고
    • In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord
    • Inoue, M. et al. In vivo pain-inhibitory role of nociceptin/orphanin FQ in spinal cord. J. Pharmacol. Exp. Ther. 305, 495-501 (2003).
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 495-501
    • Inoue, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.