Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone

Nature Immunology

Volumn 5, Issue 7, 2004, Pages 713-720

  Cinamon, Guy ^a,b   Matloubian, Mehrdad ^a,b   Lesneski, Matthew J ^a,b   Xu, Ying ^a,b   Low, Caroline ^a,b   Lu, Theresa ^a,b,d   Proia, Richard L ^c   Cyster, Jason G ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CHEMOKINE; FINGOLIMOD; LIPOPOLYSACCHARIDE; LYSOPHOSPHOLIPID; RECEPTOR PROTEIN; SPHINGOSINE 1 PHOSPHATE; ALPHA CHEMOKINE; CXCL13 PROTEIN, MOUSE; DRUG DERIVATIVE; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHOLIPID RECEPTOR; PROPANEDIOL DERIVATIVE; SPHINGOSINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DATA ANALYSIS; DOWN REGULATION; DRUG TARGETING; EMBRYO; ENZYME ACTIVITY; EXPOSURE; FOLLICULAR DENDRITIC CELL; GENE TARGETING; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN CELL; ANIMAL; CELL MOTION; CHIMERA; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; FLOW CYTOMETRY; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LIVER; METABOLISM; PRENATAL DEVELOPMENT; SPLEEN; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS; B-LYMPHOCYTES; CELL MOVEMENT; CHEMOKINES, CXC; CHIMERA; DOWN-REGULATION; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; LIPOPOLYSACCHARIDES; LIVER; MICE; MICE, TRANSGENIC; PROPYLENE GLYCOLS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; SPHINGOSINE; SPLEEN;

EID: 3242796768     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni1083     Document Type: Article

References (38)

1. Kraal, G. Cells in the marginal zone of the spleen. Int. Rev. Cytology 132, 31-73 (1992).
2. Schmidt, E.E., MacDonald, I.C. & Groom, A.C. Comparative aspects of splenic microcirculatory pathways in mammals: the region bordering the white pulp. Scanning Microsc. 7, 613-628 (1993).
3. Cyster, J.G. B cells on the front line. Nat. Immunol. 1, 9-10 (2000).
4. Martin, F. & Kearney, J.F. Marginal-zone B cells. Nat. Rev. Immunol. 2, 323-335 (2002).
5. MacLennan, I.C.M., Gray, D., Kumararatne, D.S. & Bazin, H. The lymphocytes of splenic marginal zones: a distinct B-cell lineage. Immunol. Today 3, 305-307 (1982).
6. Lu, T.T. & Cyster, J.G. Integrin-mediated long-term B cell retention in the splenic marginal zone. Science 297, 409-412 (2002).
7. Guinamard, R., Okigaki, M., Schlessinger, J. & Ravetch, J.V. Absence of marginal zone B cells in Pyk-2 deficient mice define their role in the humoral response. Nat. Immunol. 1, 31-36 (2000).
8. Chiba, K. et al. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J. Immunol. 160, 5037-5044 (1998).
9. Brinkmann, V. & Lynch, K. FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity. Curr. Opin. Immunol. 14, 569-575 (2002).
10. Rosen, H., Sanna, G. & Alfonso, C. Egress: a receptor-regulated step in lymphocyte trafficking. Immunol. Rev. 195, 160-177 (2003).
11. Mandala, S. et al. Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 296, 346-349 (2002).
12. Brinkmann, V. et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J. Biol. Chem. 277, 21453-21457 (2002).
13. Matloubian, M. et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 427, 355-360 (2004).
14. Allende, M.L., Dreier, J.L., Mandala, S. & Proia, R.L. Expression of the sphingosine-1-phosphate receptor, S1P1, on T-cells controls thymic emigration. J. Biol. Chem. 279, 15396-15401 (2004).
15. Allende, M.L. & Proia, R.L. Sphingosine-1-phosphate receptors and the development of the vascular system. Biochim. Biophys. Acta 1582, 222-227 (2002).
16. Spiegel, S. & Milstien, S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat. Rev. Mol. Cell Biol. 4, 397-407 (2003).
17. Hla, T. Signaling and biological actions of sphingosine 1-phosphate. Pharmacol. Res. 47, 401-407 (2003).
18. Pinschewer, D.D. et al. FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory. J. Immunol. 164, 5761-5770 (2000).
19. Liu, Y. et al. Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation. J. Clin. Invest. 106, 951-961 (2000).
20. Hla, T. Sphingosine 1-phosphate receptors. Prostaglandins Other Lipid Mediat. 64, 135-142 (2001).
21. Förster, R. et al. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87, 1037-1047 (1996).
22. Ansel, K.M. et al. A chemokine driven positive feedback loop organizes lymphoid follicles. Nature 406, 309-314 (2000).
23. Groeneveld, P.H., Erich, T. & Kraal, G. In vivo effects of LPS on B lymphocyte subpopulations. Migration of marginal zone-lymphocytes and IgD-blast formation in the mouse spleen. Immunobiology 170, 402-411 (1985).
24. Graler, M.H. & Goetzl, E.J. The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G protein-coupled receptors. FASEB J. 18, 551-553 (2004),
25. Liu, Y.-J., Oldfield, S. & MacLennan, I.C.M. Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones. Eur. J. Immunol. 18, 355-362 (1988).
26. 3, respectively, regulate lymphocyte recirculation and heart rate. J. Biol. Chem. 279, 13839-13848 (2004).
27. Graeler, M. & Goetzl, E.J. Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells. FASEB J. 16, 1874-1878 (2002).
28. Graeler, M., Shankar, G. & Goetzl, E.J. Cutting edge: suppression of T cell chemotaxis by sphingosine 1-phosphate. J. Immunol. 169, 4084-4087 (2002).
29. 1 G protein-coupled receptor. J. Immunol. 171, 3500-3507 (2003).
30. Steele, A.D., Szabo, I., Bednar, F. & Rogers, T.J. Interactions between opioid and chemokine receptors: heterologous desensitization. Cytokine Growth Factor Rev. 13, 209-222 (2002).
31. Rosen, H., Alfonso, C., Surh, C.D. & McHeyzer-Williams, M.G. Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist. Proc. Natl. Acad. Sci. USA 100, 10907-10912 (2003).
32. Chu, P. et al. Systematic identification of regulatory proteins critical for T-cell activation. J. Biol. 2, 21.1-21.16 (2003).
33. Karlsson, M.C. et al. Macrophages control the retention and trafficking of B lymphocytes in the splenic marginal zone. J. Exp. Med. 198, 333-340 (2003).
34. Martin, F. & Kearney, J.F. B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a " natural immune memory". Immunol. Rev. 175, 70-79 (2000).
35. Reif, K. et al. Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position. Nature 416, 94-99 (2002).
36. Hargreaves, D.C. et al. A coordinated change in chemokine responsiveness guides plasma cell movements. J. Exp. Med. 194, 45-56 (2001).
37. Forrest, M. et al. Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes. J. Pharmacol. Exp. Ther. 309, 758-768 (2004).
38. Goodnow, C.C. et al. Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. Nature 334, 676-682 (1988).