A Single Amino Acid Determines Lysophospholipid Specificity of the S1P 1 (EDG1) and LPA1 (EDG2) Phospholipid Growth Factor Receptors

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 49213-49220

  Wang, De An ^a   Lorincz, Zsolt ^a   Bautista, Debra L ^b,c   Liliom, Karoly ^a,d   Tigyi, Gabor ^a   Parrill, Abby L ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b University of Memphis   (United States)

^c EASTERN KENTUCKY UNIVERSITY   (United States)

^d INSTITUTE OF ENZYMOLOGY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROGEN BONDS; PHOSPHOLIPIDS; PROTEINS;

LIGANDS;

AMINO ACIDS;

AMINO ACID; G PROTEIN COUPLED RECEPTOR; GLUTAMIC ACID; GLUTAMINE; GROWTH FACTOR RECEPTOR; HYDROXYL GROUP; LIGAND; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; LYSOPHOSPHOLIPID; PHOSPHOLIPID; PROTEIN EDG1; PROTEIN EDG2; RECEPTOR PROTEIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; UNCLASSIFIED DRUG; DRUG DERIVATIVE; EDG 1 PROTEIN; EDG 2 PROTEIN; EDG-1 PROTEIN; EDG-2 PROTEIN; IMMEDIATE EARLY PROTEIN; IMMEDIATE EARLY PROTEINS; NUCLEAR PROTEIN; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; TRANSCRIPTION FACTOR;

ACID BASE BALANCE; ARTICLE; GENETIC CONSERVATION; HYDROGEN BOND; MATHEMATICAL MODEL; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; AMINO ACID SEQUENCE; CELL LINE; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; CELL LINE; COMPUTER SIMULATION; IMMEDIATE-EARLY PROTEINS; IMMUNOHISTOCHEMISTRY; LIGANDS; LYSOPHOSPHOLIPIDS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ALIGNMENT; SPHINGOSINE; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTORS;

EID: 0035966064     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M107301200     Document Type: Article

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