-
1
-
-
0024368359
-
Encephalitogenic T cells in the B10. PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
-
Ando DG, Clayton J, Kono D, Urban JL, and Sercarz EE (1989) Encephalitogenic T cells in the B10. PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol 124:132-143.
-
(1989)
Cell Immunol
, vol.124
, pp. 132-143
-
-
Ando, D.G.1
Clayton, J.2
Kono, D.3
Urban, J.L.4
Sercarz, E.E.5
-
2
-
-
0026602240
-
The efficacy of cyclosporin A. FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE). PG
-
Bolton C (1992) The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE). PG. Agents Actions 35:79-84.
-
(1992)
Agents Actions
, vol.35
, pp. 79-84
-
-
Bolton, C.1
-
3
-
-
0020038942
-
The effect of cyclosporin A on the adoptive transfer of experimental allergic encephalomyelitis in the Lewis rat
-
Bolton C, Allsopp G, and Cuzner ML (1982a) The effect of cyclosporin A on the adoptive transfer of experimental allergic encephalomyelitis in the Lewis rat. Clin Exp Immunol 47:127-132.
-
(1982)
Clin Exp Immunol
, vol.47
, pp. 127-132
-
-
Bolton, C.1
Allsopp, G.2
Cuzner, M.L.3
-
4
-
-
0019939437
-
Immunosuppression by cyclosporin A of experimental allergic encephalomyelitis
-
Bolton C, Borel JF, Cuzner ML, Davison AN, and Turner AM (1982b) Immunosuppression by cyclosporin A of experimental allergic encephalomyelitis. J Neurol Sci 56:147-153.
-
(1982)
J Neurol Sci
, vol.56
, pp. 147-153
-
-
Bolton, C.1
Borel, J.F.2
Cuzner, M.L.3
Davison, A.N.4
Turner, A.M.5
-
5
-
-
0031302405
-
Cell death during autoimmune demyelination: Effector but not target cells are eliminated by apoptosis
-
Bonetti B, Pohl J, Gao YL, and Raine CS (1997) Cell death during autoimmune demyelination: effector but not target cells are eliminated by apoptosis. J Immunol 159:5733-5741.
-
(1997)
J Immunol
, vol.159
, pp. 5733-5741
-
-
Bonetti, B.1
Pohl, J.2
Gao, Y.L.3
Raine, C.S.4
-
6
-
-
0024955297
-
Pharmacology of cyclosporine (sandimmune). IV. Pharmacological properties in vivo
-
Borel JF (1990) Pharmacology of cyclosporine (sandimmune). IV. Pharmacological properties in vivo. Pharmacol Rev 41:259-371.
-
(1990)
Pharmacol Rev
, vol.41
, pp. 259-371
-
-
Borel, J.F.1
-
7
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davis MD, Heise CE, Albert R, Cottens S, Hof R, Bruns C, Prieschl E, Baumruker T, Hiestand P, et al. (2002) The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem 277:21453-21457.
-
(2002)
J Biol Chem
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
Albert, R.4
Cottens, S.5
Hof, R.6
Bruns, C.7
Prieschl, E.8
Baumruker, T.9
Hiestand, P.10
-
8
-
-
0035884709
-
FTY720: Altered lymphocyte traffic results in allograft protection
-
Brinkmann V, Pinschewer DD, Feng L, and Chen S (2001) FTY720: altered lymphocyte traffic results in allograft protection. Transplantation 72:764-769.
-
(2001)
Transplantation
, vol.72
, pp. 764-769
-
-
Brinkmann, V.1
Pinschewer, D.D.2
Feng, L.3
Chen, S.4
-
9
-
-
0032525049
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
-
Chiba K, Yanagawa Y, Masubuchi Y, Kataoka H, Kawaguchi T, Ohtsuki M, and Hoshino Y (1998) FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J Immunol 160:5037-5044.
-
(1998)
J Immunol
, vol.160
, pp. 5037-5044
-
-
Chiba, K.1
Yanagawa, Y.2
Masubuchi, Y.3
Kataoka, H.4
Kawaguchi, T.5
Ohtsuki, M.6
Hoshino, Y.7
-
10
-
-
0026344595
-
Effects of FK 506 on acute experimental allergic encephalomyelitis
-
Deguchi K, Takeuchi H, Miki H, Yamada A, Touge T, Terada S, and Nishioka M (1991) Effects of FK 506 on acute experimental allergic encephalomyelitis. Transplant Proc 23:3360-3362.
-
(1991)
Transplant Proc
, vol.23
, pp. 3360-3362
-
-
Deguchi, K.1
Takeuchi, H.2
Miki, H.3
Yamada, A.4
Touge, T.5
Terada, S.6
Nishioka, M.7
-
11
-
-
0030245686
-
Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720
-
Enosawa S, Suzuki S, Kakefuda T, Li XK, and Amemiya H (1996) Induction of selective cell death targeting on mature T-lymphocytes in rats by a novel immunosuppressant, FTY720. Immunopharmacology 34:171-179.
-
(1996)
Immunopharmacology
, vol.34
, pp. 171-179
-
-
Enosawa, S.1
Suzuki, S.2
Kakefuda, T.3
Li, X.K.4
Amemiya, H.5
-
12
-
-
0028372227
-
Fungal metabolites. Part II. A potent immunosuppressive activity found in Isaria sinclairii metabolite
-
Fujita T, Inoue K, Yamamoto S, Ikumoto T, Sasaki S, Toyama R, Chiba K, Hoshino Y, and Okumoto T (1994a) Fungal metabolites. Part II. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J Antibiot (Tokyo) 47:208-215.
-
(1994)
J Antibiot (Tokyo)
, vol.47
, pp. 208-215
-
-
Fujita, T.1
Inoue, K.2
Yamamoto, S.3
Ikumoto, T.4
Sasaki, S.5
Toyama, R.6
Chiba, K.7
Hoshino, Y.8
Okumoto, T.9
-
13
-
-
0028205909
-
Fungal metabolites. Part 12. Potent immunosuppressant, 14-deoxomyriocin, (2S,3R,4R)-(E)-2-amino-3, 4-dihydroxy-2hydroxymethyleicos-6-anoic acid and structure-activity relationships of myriocin derivatives
-
Fujita T, Inoue K, Yamamoto S, Ikumoto T, Sasaki S, Toyama R, Yoneta M, Chiba K, Hoshino Y, and Okumoto T (1994b) Fungal metabolites. Part 12. Potent immunosuppressant, 14-deoxomyriocin, (2S,3R,4R)-(E)-2-amino-3, 4-dihydroxy-2hydroxymethyleicos-6-anoic acid and structure-activity relationships of myriocin derivatives. J Antibiot (Tokyo) 47:216-224.
-
(1994)
J Antibiot (Tokyo)
, vol.47
, pp. 216-224
-
-
Fujita, T.1
Inoue, K.2
Yamamoto, S.3
Ikumoto, T.4
Sasaki, S.5
Toyama, R.6
Yoneta, M.7
Chiba, K.8
Hoshino, Y.9
Okumoto, T.10
-
14
-
-
0025981021
-
T-Lymphocyte entry into the central nervous system
-
Hickey WF, Hsu BL, and Kimura H (1991) T-Lymphocyte entry into the central nervous system. J Neurosci Res 28:254-260.
-
(1991)
J Neurosci Res
, vol.28
, pp. 254-260
-
-
Hickey, W.F.1
Hsu, B.L.2
Kimura, H.3
-
15
-
-
0029918395
-
FTY720, a novel immunosuppressant possessing unique mechanisms. II. Longterm graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A
-
Hoshino Y, Suzuki C, Ohtsuki M, Masubuchi Y, Amano Y, and Chiba K (1996) FTY720, a novel immunosuppressant possessing unique mechanisms. II. Longterm graft survival induction in rat heterotopic cardiac allografts and synergistic effect in combination with cyclosporine A. Transplant Proc 28:1060-1061.
-
(1996)
Transplant Proc
, vol.28
, pp. 1060-1061
-
-
Hoshino, Y.1
Suzuki, C.2
Ohtsuki, M.3
Masubuchi, Y.4
Amano, Y.5
Chiba, K.6
-
16
-
-
0033578975
-
Immunotherapy for experimental rat autoimmune thyroiditis using a novel immunosuppressant, FTY720
-
Hozumi Y, Kobayashi E, Miyata M, and Fujimura A (1999) Immunotherapy for experimental rat autoimmune thyroiditis using a novel immunosuppressant, FTY720. Life Sci 65:1739-1745.
-
(1999)
Life Sci
, vol.65
, pp. 1739-1745
-
-
Hozumi, Y.1
Kobayashi, E.2
Miyata, M.3
Fujimura, A.4
-
17
-
-
0024157108
-
Immunosuppressive effect of FK506 on experimental allergic encephalomyelitis in rats
-
Inamura N, Hashimoto M, Nakahara K, Nakajima Y, Nishio M, Aoki H, Yamaguchi I, and Kohsaka M (1988) Immunosuppressive effect of FK506 on experimental allergic encephalomyelitis in rats. Int J Immunopharmacol 10:991-995.
-
(1988)
Int J Immunopharmacol
, vol.10
, pp. 991-995
-
-
Inamura, N.1
Hashimoto, M.2
Nakahara, K.3
Nakajima, Y.4
Nishio, M.5
Aoki, H.6
Yamaguchi, I.7
Kohsaka, M.8
-
18
-
-
0034002825
-
FTY720 prevents development of experimental autoimmune myocarditis through reduction of circulating lymphocytes
-
Kitabayashi H, Isobe M, Watanabe N, Suzuki J, Yazaki Y, and Sekiguchi M (2000) FTY720 prevents development of experimental autoimmune myocarditis through reduction of circulating lymphocytes. J Cardiovasc Pharmacol 35:410-416.
-
(2000)
J Cardiovasc Pharmacol
, vol.35
, pp. 410-416
-
-
Kitabayashi, H.1
Isobe, M.2
Watanabe, N.3
Suzuki, J.4
Yazaki, Y.5
Sekiguchi, M.6
-
19
-
-
0033980334
-
Effects of FTY720, a novel immunosuppressant, on experimental autoimmune uveoretinitis in rats
-
Kurose S, Ikeda E, Tokiwa M, Hikita N, and Mochizuki M (2000) Effects of FTY720, a novel immunosuppressant, on experimental autoimmune uveoretinitis in rats. Res 70:7-15.
-
(2000)
Res
, vol.70
, pp. 7-15
-
-
Kurose, S.1
Ikeda, E.2
Tokiwa, M.3
Hikita, N.4
Mochizuki, M.5
-
20
-
-
0032981648
-
Adhesion molecule expression and regulation on cells of the central nervous system
-
Lee SJ and Benveniste EN (1999) Adhesion molecule expression and regulation on cells of the central nervous system. J Neuroimmunol 98:77-88.
-
(1999)
J Neuroimmunol
, vol.98
, pp. 77-88
-
-
Lee, S.J.1
Benveniste, E.N.2
-
21
-
-
0035114740
-
Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720
-
Li XK, Tamura A, Fujino M, Guo L, Kakefuda T, Funeshima N, Enosawa S, Amari M, Naoe S, Amemiya H, and Suzuki S (2001) Induction of lymphocyte apoptosis in rat liver allograft with ongoing rejection by FTY720. Clin Exp Immunol 123:331-339.
-
(2001)
Clin Exp Immunol
, vol.123
, pp. 331-339
-
-
Li, X.K.1
Tamura, A.2
Fujino, M.3
Guo, L.4
Kakefuda, T.5
Funeshima, N.6
Enosawa, S.7
Amari, M.8
Naoe, S.9
Amemiya, H.10
Suzuki, S.11
-
22
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
-
Liu J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, and Schreiber SL (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807-815.
-
(1991)
Cell
, vol.66
, pp. 807-815
-
-
Liu, J.1
Farmer J.D., Jr.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
23
-
-
0024241869
-
Evidence for an immunosuppressive autoantibody in experimental allergic encephalomyelitis
-
MacPhee IA and Mason DW (1988) Evidence for an immunosuppressive autoantibody in experimental allergic encephalomyelitis. Ann N Y Acad Sci 540:718-719.
-
(1988)
Ann N Y Acad Sci
, vol.540
, pp. 718-719
-
-
MacPhee, I.A.1
Mason, D.W.2
-
24
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, et al. (2002) Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science (Wash DC) 296:346-349.
-
(2002)
Science (Wash DC)
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
Thornton, R.7
Shei, G.J.8
Card, D.9
Keohane, C.10
-
25
-
-
0026327339
-
Combination drug therapies for immunosuppression in transplantation
-
McWhinnie DL and Morris PJ (1991) Combination drug therapies for immunosuppression in transplantation. Ann Acad Med Singapore 20:498-502.
-
(1991)
Ann Acad Med Singapore
, vol.20
, pp. 498-502
-
-
McWhinnie, D.L.1
Morris, P.J.2
-
26
-
-
0036228891
-
Effects of FTY720 in MRL-lpr/lpr mice: Therapeutic potential in systemic lupus erythematosus
-
Okazaki H, Hirata D, Kamimura T, Sato H, Iwamoto M, Yoshio T, Masuyama J, Fujimura A, Kobayashi E, Kano S, and Minota S (2002) Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus. J Rheumatol 29:707-716.
-
(2002)
J Rheumatol
, vol.29
, pp. 707-716
-
-
Okazaki, H.1
Hirata, D.2
Kamimura, T.3
Sato, H.4
Iwamoto, M.5
Yoshio, T.6
Masuyama, J.7
Fujimura, A.8
Kobayashi, E.9
Kano, S.10
Minota, S.11
-
27
-
-
0017738883
-
Experimental allergic encephalomyelitis: Enhancement of cell-mediated transfer by concanavalin A
-
Panitch HS and McFarlin DE (1977) Experimental allergic encephalomyelitis: enhancement of cell-mediated transfer by concanavalin A. J Immunol 119:1134-1137.
-
(1977)
J Immunol
, vol.119
, pp. 1134-1137
-
-
Panitch, H.S.1
McFarlin, D.E.2
-
28
-
-
0001149859
-
Transfer for allergic encephalomyelitis in rats by means of lymph node cells
-
Paterson PY (1960) Transfer for allergic encephalomyelitis in rats by means of lymph node cells. J Exp Med 111:119-135.
-
(1960)
J Exp Med
, vol.111
, pp. 119-135
-
-
Paterson, P.Y.1
-
29
-
-
0025817888
-
Apoptosis in the nervous system in experimental allergic encephalomyelitis
-
Pender MP, Nguyen KB, McCombe PA, and Kerr JF (1991) Apoptosis in the nervous system in experimental allergic encephalomyelitis. J Neurol Sci 104:81-87.
-
(1991)
J Neurol Sci
, vol.104
, pp. 81-87
-
-
Pender, M.P.1
Nguyen, K.B.2
McCombe, P.A.3
Kerr, J.F.4
-
30
-
-
0034120178
-
FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion and memory
-
Pinschewer DD, Ochsenbein AF, Odermatt B, Brinkmann V, Hengartner H, and Zinkernagel RM (2000) FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion and memory. J Immunol 164:5761-5770.
-
(2000)
J Immunol
, vol.164
, pp. 5761-5770
-
-
Pinschewer, D.D.1
Ochsenbein, A.F.2
Odermatt, B.3
Brinkmann, V.4
Hengartner, H.5
Zinkernagel, R.M.6
-
31
-
-
0028676623
-
Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK506-treated patients
-
Platz KP, Mueller AR, Blumhardt G, Bachmann S, Bechstein WO, Kahl A, and Neuhaus P (1994) Nephrotoxicity after orthotopic liver transplantation in cyclosporin A and FK506-treated patients. Transpl Int 7:S52-S57.
-
(1994)
Transpl Int
, vol.7
-
-
Platz, K.P.1
Mueller, A.R.2
Blumhardt, G.3
Bachmann, S.4
Bechstein, W.O.5
Kahl, A.6
Neuhaus, P.7
-
32
-
-
0018351391
-
Adoptive transfer of experimental allergic encephalomyelitis: Incubation of rat spleen cells with specific antigen
-
Richert JR, Driscoll BF, Kies MW, and Alvord EC Jr (1979) Adoptive transfer of experimental allergic encephalomyelitis: incubation of rat spleen cells with specific antigen. J Immunol 122:494-496.
-
(1979)
J Immunol
, vol.122
, pp. 494-496
-
-
Richert, J.R.1
Driscoll, B.F.2
Kies, M.W.3
Alvord E.C., Jr.4
-
33
-
-
0032534730
-
IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: Roles of IL-6 in the activation and differentiation of autoreactive T cells
-
Samoilova EB, Horton JL, Hilliard B, Liu TS, and Chen Y (1998) IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J Immunol 161:6480-6486.
-
(1998)
J Immunol
, vol.161
, pp. 6480-6486
-
-
Samoilova, E.B.1
Horton, J.L.2
Hilliard, B.3
Liu, T.S.4
Chen, Y.5
-
34
-
-
0026059558
-
Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase
-
Schmitz GG, Walter T, Seibl R, and Kessler C (1991) Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase. Anal Biochem 192:222-231.
-
(1991)
Anal Biochem
, vol.192
, pp. 222-231
-
-
Schmitz, G.G.1
Walter, T.2
Seibl, R.3
Kessler, C.4
-
35
-
-
0033815173
-
Oral administration of cholera toxin B subunit conjugated to myelin basic protein protects against experimental autoimmune encephalomyelitis by inducing transforming growth factor-β-secreting cells and suppressing chemokine expression
-
Sun JB, Xiao BG, Lindblad M, Li BL, Link H, Czerkinsky C, and Holmgren J (2000) Oral administration of cholera toxin B subunit conjugated to myelin basic protein protects against experimental autoimmune encephalomyelitis by inducing transforming growth factor-β-secreting cells and suppressing chemokine expression. Int Immunol 12:1449-1457.
-
(2000)
Int Immunol
, vol.12
, pp. 1449-1457
-
-
Sun, J.B.1
Xiao, B.G.2
Lindblad, M.3
Li, B.L.4
Link, H.5
Czerkinsky, C.6
Holmgren, J.7
-
36
-
-
0029938103
-
Long-term graft acceptance in allografted rats and dogs by treatment with a novel immunosuppressant, FTY720
-
Suzuki S, Enosawa S, Kakefuda T, Amemiya H, Hoshino Y, and Chiba K (1996a) Long-term graft acceptance in allografted rats and dogs by treatment with a novel immunosuppressant, FTY720. Transplant Proc 28:1375-1376.
-
(1996)
Transplant Proc
, vol.28
, pp. 1375-1376
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
Amemiya, H.4
Hoshino, Y.5
Chiba, K.6
-
37
-
-
0030049234
-
A novel immunosuppressant. FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation
-
Suzuki S, Enosawa S, Kakefuda T, Shinomiya T, Amari M, Naoe S, Hoshino Y, and Chiba K (1996b) A novel immunosuppressant, FTY720, with a unique mechanism of action, induces long-term graft acceptance in rat and dog allotransplantation. Transplantation 61:200-205.
-
(1996)
Transplantation
, vol.61
, pp. 200-205
-
-
Suzuki, S.1
Enosawa, S.2
Kakefuda, T.3
Shinomiya, T.4
Amari, M.5
Naoe, S.6
Hoshino, Y.7
Chiba, K.8
-
38
-
-
0031765615
-
Immunosuppressive effect of FTY 720 on autoimmune diabetes models
-
Yan H, Suzuki K, Li XK, Amemiya H, Suzuki S, and Hiromitsu K (1998) Immunosuppressive effect of FTY 720 on autoimmune diabetes models. Transplant Proc 30:3436-3437.
-
(1998)
Transplant Proc
, vol.30
, pp. 3436-3437
-
-
Yan, H.1
Suzuki, K.2
Li, X.K.3
Amemiya, H.4
Suzuki, S.5
Hiromitsu, K.6
-
39
-
-
0032103938
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T cell infiltration into grafts but not cytokine production in vivo
-
Yanagawa Y, Sugahara K, Kataoka H, Kawaguchi T, Masubuchi Y, and Chiba K (1998) FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. II. FTY720 prolongs skin allograft survival by decreasing T cell infiltration into grafts but not cytokine production in vivo. J Immunol 160:5493-5499.
-
(1998)
J Immunol
, vol.160
, pp. 5493-5499
-
-
Yanagawa, Y.1
Sugahara, K.2
Kataoka, H.3
Kawaguchi, T.4
Masubuchi, Y.5
Chiba, K.6
-
40
-
-
0025246367
-
The T lymphocyte in experimental allergic encephalomyelitis
-
Zamvil SS and Steinman L (1990) The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev Immunol 8:579-621.
-
(1990)
Annu Rev Immunol
, vol.8
, pp. 579-621
-
-
Zamvil, S.S.1
Steinman, L.2
|