Inducible-costimulator-mediated suppression of human immunodeficiency virus type 1 replication in CD4+ T lymphocytes

Virology

Volumn 325, Issue 2, 2004, Pages 252-263

  Zhou, Xin ^a   Kubo, Makoto ^a   Nishitsuji, Hironori ^a   Kurihara, Kiyoshi ^a   Ikeda, Tamako ^a   Ohashi, Takashi ^a   Azuma, Miyuki ^a   Masuda, Takao ^a   Kannagi, Mari ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

CD28; Costimulatory molecule; HIV 1 suppression; ICOS; Immune regulation; T cell activation

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; INDUCIBLE COSTIMULATOR PROTEIN; LIGAND; MONOCLONAL ANTIBODY; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ANTIGEN EXPRESSION; ARTICLE; CELL GROWTH; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMOBILIZED CELL; MOUSE; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN FAMILY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; VESICULAR STOMATITIS VIRUS; VIRUS CELL INTERACTION; VIRUS ENVELOPE; VIRUS REPLICATION; VIRUS TYPING;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD28; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; ANTIVIRAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIVISION; CELL SURVIVAL; CYTOKINES; HIV-1; HUMANS; ISOXAZOLES; LIGANDS; MICE; RECEPTORS, HIV; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; VESICULAR STOMATITIS VIRUS;

EID: 3142638815     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virol.2004.04.037     Document Type: Article

References (59)

1. Adachi A., Gendelman H.E., Koenig S., Folks T., Willey R., Rabson A., Martin M.A. Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J. Virol. 59(2):1986;284-291
2. Avraham A., Jung S., Samuels Y., Seger R., Ben-Neriah Y. Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes. Eur. J. Immunol. 28(8):1998;2320-2330
3. Azuma M., Ito D., Yagita H., Okumura K., Phillips J.H., Lanier L.L., Somoza C. B70 antigen is a second ligand for CTLA-4 and CD28. Nature. 366(6450):1993;76-79
4. Beier K.C., Hutloff A., Dittrich A.M., Heuck C., Rauch A., Buchner K., Ludewig B., Ochs H.D., Mages H.W., Kroczek R.A. Induction, binding specificity and function of human ICOS. Eur. J. Immunol. 30(12):2000;3707-3717
5. Brazelton T.R., Morris R.E. Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide. Curr. Opin. Immunol. 8(5):1996;710-720
6. Brunet J.F., Denizot F., Luciani M.F., Roux-Dosseto M., Suzan M., Mattei M.G., Golstein P. A new member of the immunoglobulin superfamily - CTLA-4. Nature. 328(6127):1987;267-270
7. Buonfiglio D., Bragardo M., Redoglia V., Vaschetto R., Bottarel F., Bonissoni S., Bensi T., Mezzatesta C., Janeway C.A. Jr., Dianzani U. The T cell activation molecule H4 and the CD28-like molecule ICOS are identical. Eur. J. Immunol. 30(12):2000;3463-3467
8. Coyle A.J., Lehar S., Lloyd C., Tian J., Delaney T., Manning S., Nguyen T., Burwell T., Schneider H., Gonzalo J.A., Gosselin M., Owen L.R., Rudd C.E., Gutierrez-Ramos J.C. The CD28-related molecule ICOS is required for effective T cell-dependent immune responses. Immunity. 13(1):2000;95-105
9. Diegel M.L., Moran P.A., Gilliland L.K., Damle N.K., Hayden M.S., Zarling J.M., Ledbetter J.A. Regulation of HIV production by blood mononuclear cells from HIV-infected donors: II. HIV-1 production depends on T cell-monocyte interaction. AIDS Res. Hum. Retroviruses. 9(5):1993;465-473
10. Dong H., Zhu G., Tamada K., Chen L. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion. Nat. Med. 5(12):1999;1365-1369
11. Faris M., Kokot N., Lee L., Nel A.E. Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation. J. Biol. Chem. 271(44):1996;27366-27373
12. Finzi D., Hermankova M., Pierson T., Carruth L.M., Buck C., Chaisson R.E., Quinn T.C., Chadwick K., Margolick J., Brookmeyer R., Gallant J., Markowitz M., Ho D.D., Richman D.D., Siliciano R.F. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science. 278(5341):1997;1295-1300
13. Frauwirth K.A., Thompson C.B. Activation and inhibition of lymphocytes by costimulation. J. Clin. Invest. 109(3):2002;295-299
14. Freeman G.J., Long A.J., Iwai Y., Bourque K., Chernova T., Nishimura H., Fitz L.J., Malenkovich N., Okazaki T., Byrne M.C., Horton H.F., Fouser L., Carter L., Ling V., Bowman M.R., Carreno B.M., Collins M., Wood C.R., Honjo T. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J. Exp. Med. 192(7):2000;1027-1034
15. Hara T., Fu S.M., Hansen J.A. Human T cell activation. II. A new activation pathway used by a major T cell population via a disulfide-bonded dimer of a 44 kilodalton polypeptide (9.3 antigen). J. Exp. Med. 161(6):1985;1513-1524
16. Harhaj E.W., Sun S.C. IkappaB kinases serve as a target of CD28 signaling. J. Biol. Chem. 273(39):1998;25185-25190
17. Hehner S.P., Hofmann T.G., Dienz O., Droge W., Schmitz M.L. Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription. J. Biol. Chem. 275(24):2000;18160-18171
18. Ho D.D., Moudgil T., Alam M. Quantitation of human immunodeficiency virus type 1 in the blood of infected persons. N. Engl. J. Med. 321(24):1989;1621- 1625
19. Ho D.D., Neumann A.U., Perelson A.S., Chen W., Leonard J.M., Markowitz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature. 373(6510):1995;123-126
20. Hutloff A., Dittrich A.M., Beier K.C., Eljaschewitsch B., Kraft R., Anagnostopoulos I., Kroczek R.A. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28. Nature. 397(6716):1999;263-266
21. Kane L.P., Lin J., Weiss A. It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. Trends Immunol. 23(8):2002;413-420
22. Kannagi M., Masuda T., Hattori T., Kanoh T., Nasu K., Yamamoto N., Harada S. Interference with human immunodeficiency virus (HIV) replication by CD8+ T cells in peripheral blood leukocytes of asymptomatic HIV carriers in vitro. J. Virol. 64(7):1990;3399-3406
23. Koyanagi Y., Miles S., Mitsuyasu R.T., Merrill J.E., Vinters H.V., Chen I.S. Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science. 236(4803):1987;819-822
24. Krummel M.F., Allison J.P. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J. Exp. Med. 182(2):1995;459-465
25. Lanier L.L., O'Fallon S., Somoza C., Phillips J.H., Linsley P.S., Okumura K., Ito D., Azuma M. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J. Immunol. 154(1):1995;97-105
26. Latchman Y., Wood C.R., Chernova T., Chaudhary D., Borde M., Chernova I., Iwai Y., Long A.J., Brown J.A., Nunes R., Greenfield E.A., Bourque K., Boussiotis V.A., Carter L.L., Carreno B.M., Malenkovich N., Nishimura H., Okazaki T., Honjo T., Sharpe A.H., Freeman G.J. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat. Immunol. 2(3):2001;261-268
27. Lenschow D.J., Walunas T.L., Bluestone J.A. CD28/B7 system of T cell costimulation. Annu. Rev. Immunol. 14:1996;233-258
28. Levine B.L., Mosca J.D., Riley J.L., Carroll R.G., Vahey M.T., Jagodzinski L.L., Wagner K.F., Mayers D.L., Burke D.S., Weislow O.S., St Louis D.C., June C.H. Antiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation. Science. 272(5270):1996;1939-1943
29. Linsley P.S., Clark E.A., Ledbetter J.A. T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1. Proc. Natl. Acad. Sci. U. S. A. 87(13):1990;5031-5035
30. Lucia M.B., Buonfiglio D., Bottarel F., Bensi T., Rutella S., Rumi C., Ortona L., Janeway C.A. Jr., Cauda R., Dianzani U. Expression of the novel T cell activation molecule hpH4 in HIV-infected patients: correlation with disease status. AIDS Res. Hum. Retroviruses. 16(6):2000;549-557
31. Manna S.K., Aggarwal B.B. Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression. J. Immunol. 162(4):1999;2095-2102
32. Masuda T., Planelles V., Krogstad P., Chen I.S. Genetic analysis of human immunodeficiency virus type 1 integrase and the U3 att site: unusual phenotype of mutants in the zinc finger-like domain. J. Virol. 69(11):1995;6687-6696
33. Nishimura H., Honjo T. PD-1: an inhibitory immunoreceptor involved in peripheral tolerance. Trends Immunol. 22(5):2001;265-268
34. Nunes J.A., Collette Y., Truneh A., Olive D., Cantrell D.A. The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras. J. Exp. Med. 180(3):1994;1067-1076
35. Oki S., Kohsaka T., Azuma M. Augmentation of CTLA-4 expression by wortmannin: involvement of lysosomal sorting properties of CTLA-4. Int. Immunol. 11(9):1999;1563-1571
36. Pantaleo G., Graziosi C., Demarest J.F., Butini L., Montroni M., Fox C.H., Orenstein J.M., Kotler D.P., Fauci A.S. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature. 362(6418):1993;355-358
37. Perelson A.S., Neumann A.U., Markowitz M., Leonard J.M., Ho D.D. HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science. 271(5255):1996;1582-1586
38. Piatak M. Jr., Saag M.S., Yang L.C., Clark S.J., Kappes J.C., Luk K.C., Hahn B.H., Shaw G.M., Lifson J.D. High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR. Science. 259(5102):1993;1749- 1754
39. Planelles V., Haislip A., Withers-Ward E.S., Stewart S.A., Xie Y., Shah N.P., Chen I.S. A new reporter system for detection of retroviral infection. Gene Ther. 2(6):1995;369-376
40. Poon B., Grovit-Ferbas K., Stewart S.A., Chen I.S. Cell cycle arrest by Vpr in HIV-1 virions and insensitivity to antiretroviral agents. Science. 281(5374):1998;266-269
41. Raab M., Pfister S., Rudd C.E. CD28 signaling via VAV/SLP 76 adaptors: regulation of cytokine transcription independent of TCR ligation. Immunity. 15(6):2001;921-933
42. Sakamoto S., Tezuka K., Tsuji T., Hori N., Tamatani T. AILIM/ICOS: its expression and functional analysis with monoclonal antibodies. Hybrid. Hybridomics. 20(5-6):2001;293-303
43. Salojin K.V., Zhang J., Delovitch T.L. TCR and CD28 are coupled via ZAP-70 to the activation of the Vav/Rac-1-/PAK-1/p38 MAPK signaling pathway. J. Immunol. 163(2):1999;844-853
44. Sharpe A.H., Freeman G.J. The B7-CD28 superfamily. Nat. Rev. Immunol. 2(2):2002;116-126
45. Smithgall M.D., Wong J.G., Linsley P.S., Haffar O.K. Costimulation of CD4+ T cells via CD28 modulates human immunodeficiency virus type 1 infection and replication in vitro. AIDS Res. Hum. Retroviruses. 11(8):1995;885-892
46. Swallow M.M., Wallin J.J., Sha W.C. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha. Immunity. 11(4):1999;423-432
47. Tamatani T., Tezuka K., Hanzawa-Higuchi N. AILIM/ICOS: a novel lymphocyte adhesion molecule. Int. Immunol. 12(1):2000;51-55
48. Tseng S.Y., Otsuji M., Gorski K., Huang X., Slansky J.E., Pai S.I., Shalabi A., Shin T., Pardoll D.M., Tsuchiya H. B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J. Exp. Med. 193(7):2001;839-846
49. Tsurutani N., Kubo M., Maeda Y., Ohashi T., Yamamoto N., Kannagi M., Masuda T. Identification of critical amino acid residues in human immunodeficiency virus type 1 IN required for efficient proviral DNA formation at steps prior to integration in dividing and nondividing cells. J. Virol. 74(10):2000;4795-4806
50. Tuosto L., Costanzo A., Guido F., Marinari B., Vossio S., Moretti F., Levrero M., Piccolella E. Mitogen-activated kinase kinase kinase 1 regulates T cell receptor- and CD28-mediated signaling events which lead to NF-kappaB activation. Eur. J. Immunol. 30(9):2000;2445-2454
51. Walker C.M., Moody D.J., Stites D.P., Levy J.A. CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication. Science. 234(4783):1986;1563-1566
52. Walker B.D., Chakrabarti S., Moss B., Paradis T.J., Flynn T., Durno A.G., Blumberg R.S., Kaplan J.C., Hirsch M.S., Schooley R.T. HIV-specific cytotoxic T lymphocytes in seropositive individuals. Nature. 328(6128):1987;345-348
53. Walunas T.L., Lenschow D.J., Bakker C.Y., Linsley P.S., Freeman G.J., Green J.M., Thompson C.B., Bluestone J.A. CTLA-4 can function as a negative regulator of T cell activation. Immunity. 1(5):1994;405-413
54. Wei X., Ghosh S.K., Taylor M.E., Johnson V.A., Emini E.A., Deutsch P., Lifson J.D., Bonhoeffer S., Nowak M.A., Hahn B.H., et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature. 373(6510):1995;117-122
55. Wong J.K., Hezareh M., Gunthard H.F., Havlir D.V., Ignacio C.C., Spina C.A., Richman D.D. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science. 278(5341):1997;1291-1295
56. Yee J.K., Friedmann T., Burns J.C. Generation of high-titer pseudotyped retroviral vectors with very broad host range. Methods Cell Biol. 43(Pt. A):1994;99-112
57. Yoshinaga S.K., Whoriskey J.S., Khare S.D., Sarmiento U., Guo J., Horan T., Shih G., Zhang M., Coccia M.A., Kohno T., Tafuri-Bladt A., Brankow D., Campbell P., Chang D., Chiu L., Dai T., Duncan G., Elliott G.S., Hui A., McCabe S.M., Scully S., Shahinian A., Shaklee C.L., Van G., Mak T.W., et al. T-cell co-stimulation through B7RP-1 and ICOS. Nature. 402(6763):1999;827-832
58. Youngnak P., Kozono Y., Kozono H., Iwai H., Otsuki N., Jin H., Omura K., Yagita H., Pardoll D.M., Chen L., Azuma M. Differential binding properties of B7-H1 and B7-DC to programmed death-1. Biochem. Biophys. Res. Commun. 307(3):2003;672-677
59. Zack J.A., Arrigo S.J., Weitsman S.R., Go A.S., Haislip A., Chen I.S. HIV-1 entry into quiescent primary lymphocytes: molecular analysis reveals a labile, latent viral structure. Cell. 61(2):1990;213-222