AILIM/ICOS: Its expression and functional analysis with monoclonal antibodies

Hybridoma and Hybridomics

Volumn 20, Issue 5-6, 2001, Pages 293-303

  Sakamoto, Shinji ^a   Tezuka, Katsunari ^a   Tsuji, Takashi ^a   Hori, Nobuaki ^a   Tamatani, Takuya ^a  

^a JT Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCIBLE LYMPHOCYTE IMMUNOMEDIATORY MOLECULE; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; CHIMERIC PROTEIN; INDUCIBLE T CELL COSTIMULATOR; MONOCLONAL ANTIBODY; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; LIGAND BINDING; LYMPH NODE CELL; MONONUCLEAR CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SPECIES DIFFERENCE; SPLEEN CELL; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

ANIMALIA;

EID: 0035744676     PISSN: 15368599     EISSN: None     Source Type: Journal    
DOI: 10.1089/15368590152740699     Document Type: Article

References (35)

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11. CTLA-4 ligation blocks CD28-dependent T cell activation
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14. ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
15. T-cell costimulation through B7RP-1 and ICOS
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19. B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalpha
20. Molecular cloning and characterization of murine ICOS and identification of B7h as ICOS ligand
21. Characterization of a new human B7-related protein: B7RP-1 is the ligand to the co-stimulatory protein ICOS
22. Identification of GL50, a novel B7-like protein that functionally binds to ICOS receptor
23. Characterization of human inducible costimulator ligand expression and function
24. ICOS co-stimulatory receptor is essential for T-cell activation and function
25. ICOS is critical for CD40-mediated antibody class switching
26. ICOS is essential for effective T-helper-cell responses
27. Ligand-induced activation of chimeric receptors between the erythropoietin receptor and receptor tyrosine kinases
28. pEF-BOS, a powerful mammalian expression vector
29. A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor
30. CD44 is the principal cell surface receptor for hyaluronate
31. Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3)
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34. ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses
35. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE