-
1
-
-
0030281442
-
Combining mutagenesis and genomics in the mouse - Closing the phenotype gap
-
Brown SD, Peters J. Combining mutagenesis and genomics in the mouse - closing the phenotype gap. Trends Genet 1996; 12: 433-435.
-
(1996)
Trends Genet.
, vol.12
, pp. 433-435
-
-
Brown, S.D.1
Peters, J.2
-
2
-
-
0032565508
-
Large scale ENU screens in the mouse: Genetics meets genomics
-
Hrabe de Angelis M, Balling R. Large scale ENU screens in the mouse: genetics meets genomics. Mutat Res 1998; 400: 25-32.
-
(1998)
Mutat. Res.
, vol.400
, pp. 25-32
-
-
Hrabe de Angelis, M.1
Balling, R.2
-
3
-
-
0032837860
-
Mouse ENU mutagenesis
-
Justice MJ, Noveroske JK, Weber JS, Zheng B, Bradley A. Mouse ENU mutagenesis. Hum Mol Genet 1999; 8: 1955-1963.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1955-1963
-
-
Justice, M.J.1
Noveroske, J.K.2
Weber, J.S.3
Zheng, B.4
Bradley, A.5
-
4
-
-
0035370789
-
Systematic approaches to mouse mutagenesis
-
Brown SD, Balling R. Systematic approaches to mouse mutagenesis. Curr Opin Genet Dev 2001; 11: 268-273.
-
(2001)
Curr. Opin. Genet. Dev.
, vol.11
, pp. 268-273
-
-
Brown, S.D.1
Balling, R.2
-
5
-
-
0032170215
-
Genetic and physical mapping of the Lps locus - Identification of the Toll-4 receptor as a candidate gene in the critical region
-
Poltorak A, Smirnova I, He XL et al. Genetic and physical mapping of the Lps locus - identification of the Toll-4 receptor as a candidate gene in the critical region. Blood Cells Mol Dis 1998; 24: 340-355.
-
(1998)
Blood Cells Mol. Dis.
, vol.24
, pp. 340-355
-
-
Poltorak, A.1
Smirnova, I.2
He, X.L.3
-
6
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
7
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990; 249: 1431-1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
8
-
-
0029919991
-
Resistance to endotoxin shock and reduced dissemination of Gram-negative bacteria in CD14-deficient mice
-
Haziot A, Ferrero E, Kontgen F et al. Resistance to endotoxin shock and reduced dissemination of Gram-negative bacteria in CD14-deficient mice. Immunity 1996; 4: 407-414.
-
(1996)
Immunity
, vol.4
, pp. 407-414
-
-
Haziot, A.1
Ferrero, E.2
Kontgen, F.3
-
9
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R, Akashi S, Ogata H et al. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999; 189: 1777-1782.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
-
10
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol 2002; 3: 667-672.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
-
11
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai T, Adachi O, Ogawa T, Takeda K, Akira S. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 1999; 11: 115-122.
-
(1999)
Immunity
, vol.11
, pp. 115-122
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
12
-
-
0037129212
-
Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4
-
Suzuki N, Suzuki S, Duncan GS et al. Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4. Nature 2002; 416: 750-756.
-
(2002)
Nature
, vol.416
, pp. 750-756
-
-
Suzuki, N.1
Suzuki, S.2
Duncan, G.S.3
-
13
-
-
0033561039
-
TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling
-
Lomaga MA, Yeh WC, Sarosi I et al. TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. Genes Dev 1999; 13: 1015-1024.
-
(1999)
Genes Dev.
, vol.13
, pp. 1015-1024
-
-
Lomaga, M.A.1
Yeh, W.C.2
Sarosi, I.3
-
15
-
-
0018858071
-
The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin
-
Michalek SM, Moore RN, McGhee JR, Rosenstreich DL, Mergenhagen SE. The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin. J Infect Dis 1980; 141: 55-63.
-
(1980)
J. Infect. Dis.
, vol.141
, pp. 55-63
-
-
Michalek, S.M.1
Moore, R.N.2
McGhee, J.R.3
Rosenstreich, D.L.4
Mergenhagen, S.E.5
-
16
-
-
0022612671
-
Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin
-
Freudenberg MA, Keppler D, Galanos C. Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun 1986; 51: 891-895.
-
(1986)
Infect. Immun.
, vol.51
, pp. 891-895
-
-
Freudenberg, M.A.1
Keppler, D.2
Galanos, C.3
-
17
-
-
0022411888
-
Passive immunization against cachectin/tumor necrosis factor (TNF) protects mice from the lethal effect of endotoxin
-
Beutler B, Milsark IW, Cerami A. Passive immunization against cachectin/tumor necrosis factor (TNF) protects mice from the lethal effect of endotoxin. Science 1985; 229: 869-871.
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.3
-
18
-
-
0033574415
-
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
-
Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 1999; 274: 10689-10692.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10689-10692
-
-
Chow, J.C.1
Young, D.W.2
Golenbock, D.T.3
Christ, W.J.4
Gusovsky, F.5
-
19
-
-
0027475023
-
A comparison between two methods for measuring tumor necrosis factor in biological fluids
-
Garrelds IM, Zijlstra FJ, Tak CJAM, Bonta IL, Beckmann I, Ben-Efraim S. A comparison between two methods for measuring tumor necrosis factor in biological fluids. Agents Actions 1993; 38 (Suppl. C): C89-C91.
-
(1993)
Agents Actions
, vol.38
, Issue.SUPPL. C
-
-
Garrelds, I.M.1
Zijlstra, F.J.2
Tak, C.J.A.M.3
Bonta, I.L.4
Beckmann, I.5
Ben-Efraim, S.6
-
20
-
-
0001371506
-
High susceptibility of strain A mice to endotoxin and endotoxin-red blood cell mixtures
-
Heppner G, Weiss DW. High susceptibility of strain A mice to endotoxin and endotoxin-red blood cell mixtures. J Bacteriol 1965; 90: 696-703.
-
(1965)
J. Bacteriol.
, vol.90
, pp. 696-703
-
-
Heppner, G.1
Weiss, D.W.2
-
21
-
-
0016294676
-
Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic responses to lipopolysaccharides
-
Watson J, Riblet R. Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic responses to lipopolysaccharides. J Exp Med 1974; 140: 1147-1161.
-
(1974)
J. Exp. Med.
, vol.140
, pp. 1147-1161
-
-
Watson, J.1
Riblet, R.2
-
22
-
-
0018204171
-
Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice
-
Coutinho A, Meo T. Genetic basis for unresponsiveness to lipopolysaccharide in C57BL/10Cr mice. Immunogenetics 1978; 7: 17-24.
-
(1978)
Immunogenetics
, vol.7
, pp. 17-24
-
-
Coutinho, A.1
Meo, T.2
-
23
-
-
0035817925
-
Ma1 (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald KA, Palsson-McDermott EM, Bowie AG et al. Ma1 (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001; 413: 78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
-
24
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng T, Barton GM, Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol 2001; 2: 835-841.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
25
-
-
0032127279
-
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function
-
Adachi O, Kawai T, Takeda, K et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 1998; 9: 143-150.
-
(1998)
Immunity
, vol.9
, pp. 143-150
-
-
Adachi, O.1
Kawai, T.2
Takeda, K.3
-
26
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408: 740-745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
27
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 2002; 3: 196-200.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
-
28
-
-
0034307624
-
Tumor necrosis factor receptor-associated factor 6 (TRAF6) deficiency results in exencephaly and is required for apoptosis within the developing CNS
-
Lomaga MA, Henderson JT, Elia AJ et al. Tumor necrosis factor receptor-associated factor 6 (TRAF6) deficiency results in exencephaly and is required for apoptosis within the developing CNS. J Neurosci 2000; 20: 7384-7393.
-
(2000)
J. Neurosci.
, vol.20
, pp. 7384-7393
-
-
Lomaga, M.A.1
Henderson, J.T.2
Elia, A.J.3
-
29
-
-
0034597766
-
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains
-
Xu Y, Tao X, Shen B et al. Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature 2000; 408: 111-115.
-
(2000)
Nature
, vol.408
, pp. 111-115
-
-
Xu, Y.1
Tao, X.2
Shen, B.3
-
30
-
-
0018070597
-
Macrophage sensitivity to endotoxin. Genetic control by a single codominant gene
-
Rosenstreich D, Vogel SN, Jacques AR, Wahl LM, Oppenheim JJ. Macrophage sensitivity to endotoxin. Genetic control by a single codominant gene. J Immunol 1978; 121: 1664-1670.
-
(1978)
J. Immunol.
, vol.121
, pp. 1664-1670
-
-
Rosenstreich, D.1
Vogel, S.N.2
Jacques, A.R.3
Wahl, L.M.4
Oppenheim, J.J.5
|