Chromosome translocations: Dangerous liaisons revisited

Nature Reviews Cancer

Volumn 1, Issue 3, 2001, Pages 245-250

  Rowley, Janet D ^a  

^a UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL TRANSFORMATION; CYTOGENETICS; FORECASTING; GENE TRANSLOCATION; GENETICS; HISTORY; HUMAN; MYELOID LEUKEMIA; NEOPLASM; PHILADELPHIA 1 CHROMOSOME;

CELL TRANSFORMATION, NEOPLASTIC; CYTOGENETICS; FORECASTING; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HUMANS; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; NEOPLASMS; PHILADELPHIA CHROMOSOME; TRANSLOCATION, GENETIC;

EID: 0035750347     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/35106108     Document Type: Article

References (25)

1. Boveri, T. in Zur Frage der Entstehung maligner Tumoren (Gustav Fischer, Jena, 1914).
2. Levan, A. Some current problems of cancer cytogenetics. Hereditas 57, 343-355 (1967).
3. Nowell, P. & Hungerford, D. A minute chromosome in human granulocytic leukemia. Science 132, 1497 (1960).
4. Rowley, J. D. A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 243, 290-293 (1973).
5. de Klein, A. A. Cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukemia. Nature 300, 765-767 (1982).
6. Heisterkamp, N. et al. Localization of the c-ABL oncogene adjacent to a translocation breakpoint in chronic myelocytic leukemia. Nature 306, 239-242 (1983).
7. Groffen, J. et al. Philadelphia chromosomal breakpoints are clustered within a limited region, BCR, on chromosome 22. Cell 36, 93-99 (1984).
8. Shtivelman, E., Lifschitz, B., Gale, R. P. & Canaani, E. Fused transcript of ABL and BCR genes in chronic myelogenous leukaemia. Nature 315, 550-554 (1985).
9. Jaffe, E. S., Harris, N. L., Stein, H. & Vardiman, J. W. (eds) World Health Organization Classification of Tumours, Pathology and Genetics: Tumours of the Hematopoietic and Lymphoid Tissues (IARC, Lyon, 2001).
10. Berger, R., Chen, S. J. & Chen, Z. Philadelphia-positive acute leukemia. Cytogenetic and molecular aspects. Cancer Genet. Cytogenet. 44, 143-152 (1990).
11. Hermans, A. et al. Unique fusion of BCR and c-ABL genes in Philadelphia chromosome positive acute lymphoblastic leukemia. Cell 64, 343 (1987).
12. Witte, O. N., Dasgupta, A. & Baltimore, D. Abelson murine leukemia virus protein is phosphorylated in vitro to form phosphotyrosine. Nature 281, 396-398 (1980).
13. Konopka, J. B., Watanabe, S. M. & Witte, O. N. An alteration of the human c-ABL protein in K562 leukemia cells unmasks associated tyrosine kinase activity. Cell 37, 1035-1042 (1984).
14. Daley, G. Q., Van Etten, R. A. & Baltimore, D. Induction of chronic myelogenous leukemia in mice by the p210 BCR/ABL gene of the Philadelphia chromosome. Science 247, 824 (1990).
15. Fialkow, P. J. in Genes and Cancer (eds Bishop, J. M., Rowley, J. D. & Greaves, M.) 215-226 (Alan R. Liss, New York, 1984).
16. Druker, B. J. et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N. Engl. J. Med. 344, 1038-1042 (2001).
17. Zech, L., Haglund, U., Nilsson, K. & Klein, G. Characteristic chromosomal abnormalities in biopsies and lymphoid-cell lines from patients with Burkitt and non-Burkitt lymphomas. Int. J. Cancer 17, 47-56 (1976).
18. Dalla-Favera, R. et al. Human c-MYC one gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells. Proc. Natl Acad. Sci. USA 79, 7824-7827 (1982).
19. Taub, R. et al. Translocation of the c-MYC gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells. Proc. Natl Acad. Sci. USA 79, 7837-7841 (1982).
20. ar-Rushdi, A. et al. Differential expression of the translocated and the untranslocated c-MYC oncogene in Burkitt lymphoma. Science 222, 390-393 (1983).
21. Adams, J. M. et al. The c-Myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature 318, 6046 (1985).
22. Fukuhara, S., Rowley, J. D., Variakojis, D. & Golomb, H. M. Chromosome abnormalities in poorly differentiated lymphocytic leukemia. Cancer Res. 39, 3119-3128 (1979).
23. Tsujimoto, Y., Finger, L. R., Yunis, J., Nowell, P. C. & Croce, C. M. Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 266, 1097-1099 (1984).
24. Vaux, D. L., Cory, S. & Adams, J. M. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-Myc to immortalize pre-B cells. Nature 335, 440-442 (1988).
25. Rowley, J. D. Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia. Ann. Genet. 16, 109-112 (1973).