-
2
-
-
0024308795
-
National survey of patterns of care for brain-tumor patients
-
Mahaley MS, Mettlin C, Natarjan N, et al. National survey of patterns of care for brain-tumor patients. J Neurosurg 1989; 71: 826-836.
-
(1989)
J. Neurosurg.
, vol.71
, pp. 826-836
-
-
Mahaley, M.S.1
Mettlin, C.2
Natarjan, N.3
-
3
-
-
0032955244
-
Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction
-
Inaba M, Sawaa H, Sadata A, Hamada H. Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction, Jpn d Cancer Res 1999; 90: 349-354.
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 349-354
-
-
Inaba, M.1
Sawaa, H.2
Sadata, A.3
Hamada, H.4
-
4
-
-
0034186366
-
Prodrug activation enzymes in cancer gene therapy
-
Aghi M, Hochberg F, Breakfield X. Prodrug activation enzymes in cancer gene therapy. J Gene Med 2000; 2: 148-164.
-
(2000)
J. Gene Med.
, vol.2
, pp. 148-164
-
-
Aghi, M.1
Hochberg, F.2
Breakfield, X.3
-
5
-
-
0032481577
-
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies
-
Aghi M, Kramm CM, Chao T, et al. Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. J Natl Cancer Inst 1998; 90: 370-380.
-
(1998)
J. Natl. Cancer Inst.
, vol.90
, pp. 370-380
-
-
Aghi, M.1
Kramm, C.M.2
Chao, T.3
-
6
-
-
0026445469
-
Gene therapy of malignant brain tumors: A rat glioma line bearing the herpes simplex virus type-1 thymidine kinase gene and wild type retrovirus kills other tumor cells
-
Takamiya Y, Short MP, Ezzedine ZD, et al. Gene therapy of malignant brain tumors: a rat glioma line bearing the herpes simplex virus type-1 thymidine kinase gene and wild type retrovirus kills other tumor cells. J Neurosci Res 1992; 33: 493-503.
-
(1992)
J. Neurosci. Res.
, vol.33
, pp. 493-503
-
-
Takamiya, Y.1
Short, M.P.2
Ezzedine, Z.D.3
-
7
-
-
0029991063
-
Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene. Long-term follow-up by magnetic resonance imaging
-
Maron A, Gustin T, Le Roux A, et al. Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene. Long-term follow-up by magnetic resonance imaging. Gene Ther 1996; 3: 315-322.
-
(1996)
Gene Ther.
, vol.3
, pp. 315-322
-
-
Maron, A.1
Gustin, T.2
Le Roux, A.3
-
8
-
-
0032080867
-
Adenovirus mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil
-
Kanai F, Kawakami T, Hamada H, et al. Adenovirus mediated transduction of Escherichia coli uracil phosphoribosyltransferase gene sensitizes cancer cells to low concentrations of 5-fluorouracil. Cancer Res 1998; 58: 1946-1951.
-
(1998)
Cancer Res.
, vol.58
, pp. 1946-1951
-
-
Kanai, F.1
Kawakami, T.2
Hamada, H.3
-
9
-
-
0036468901
-
Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas
-
Miller CR, Williams CR, Buchsbaum DJ, Gillespie GY. Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas. Cancer Res 2002; 62: 773-780.
-
(2002)
Cancer Res.
, vol.62
, pp. 773-780
-
-
Miller, C.R.1
Williams, C.R.2
Buchsbaum, D.J.3
Gillespie, G.Y.4
-
12
-
-
0032740736
-
Combined radiation and enzyme/prodrug treatment for head and neck cancer in an orthotopic animal model
-
Hamstra DA, Rice DJ, Pu A, et al. Combined radiation and enzyme/prodrug treatment for head and neck cancer in an orthotopic animal model. Radiat Res 1999; 152: 499-507.
-
(1999)
Radiat. Res.
, vol.152
, pp. 499-507
-
-
Hamstra, D.A.1
Rice, D.J.2
Pu, A.3
-
13
-
-
0034547928
-
Yeast cytosine deaminase improves radio sensitization and bystander effect by 5-fluorocytosine of human colorectal xenografts
-
Kievit E, Nyati MK, Ng E. Yeast cytosine deaminase improves radio sensitization and bystander effect by 5-fluorocytosine of human colorectal xenografts. Cancer Res 2000; 60: 6649-6655.
-
(2000)
Cancer Res.
, vol.60
, pp. 6649-6655
-
-
Kievit, E.1
Nyati, M.K.2
Ng, E.3
-
14
-
-
85047696411
-
Local tumor irradiation augments the anti-tumor effect of cytokine producing autologous cancer cell vaccines in a murine glioma model
-
LumniczkyK, Désaknai Sz, Mangel L, et al. Local tumor irradiation augments the anti-tumor effect of cytokine producing autologous cancer cell vaccines in a murine glioma model. Cancer Gene Ther 2002; 9: 44-52.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 44-52
-
-
Lumniczky, K.1
Désaknai, Sz.2
Mangel, L.3
-
15
-
-
0035699639
-
Brain tumor treatment with IL-2 and IL-12 producing autologous cancer cell vaccines
-
Désaknai S, Lumniczky K, Hidvégi EJ, et al. Brain tumor treatment with IL-2 and IL-12 producing autologous cancer cell vaccines. Adv Exp Med Biol 2001; 495: 369-372.
-
(2001)
Adv. Exp. Med. Biol.
, vol.495
, pp. 369-372
-
-
Désaknai, S.1
Lumniczky, K.2
Hidvégi, E.J.3
-
16
-
-
0030070724
-
Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing full-length virus genome
-
Miyake S, Makimura M, Kanegae Y, et al. Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing full-length virus genome. Proc Natl Acad Sci U S A 1996; 93: 1320-1324.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 1320-1324
-
-
Miyake, S.1
Makimura, M.2
Kanegae, Y.3
-
17
-
-
0028202066
-
Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus mediated gene transfer in vivo
-
Chen SH, Shine HD, Goodman JC, et al. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus mediated gene transfer in vivo. Proc Natl Acad Sci U S A 1994; 91: 3054-3057.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 3054-3057
-
-
Chen, S.H.1
Shine, H.D.2
Goodman, J.C.3
-
18
-
-
0028860038
-
Long-term rat survival after malignant brain tumor regression by retroviral gene therapy
-
Izquiredo M, Cortes M, Felipe P, et al. Long-term rat survival after malignant brain tumor regression by retroviral gene therapy. Gene Ther 1995; 2: 66-69.
-
(1995)
Gene Ther.
, vol.2
, pp. 66-69
-
-
Izquiredo, M.1
Cortes, M.2
Felipe, P.3
-
19
-
-
0034136802
-
Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors
-
Trask TW, Trask RP, Aguilar-Cordova E, et al. Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol Ther 2000; 2: 195-203.
-
(2000)
Mol. Ther.
, vol.2
, pp. 195-203
-
-
Trask, T.W.1
Trask, R.P.2
Aguilar-Cordova, E.3
-
20
-
-
0033588816
-
A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
-
GLI328 European-Canadian Study Group
-
Shand N, Weber F, Mariani L, et al. A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum Gene Ther 1999; 10: 2325-2335.
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 2325-2335
-
-
Shand, N.1
Weber, F.2
Mariani, L.3
-
21
-
-
2442767029
-
A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma
-
Study Group on Gene Therapy for Glioblastoma
-
Klatzmann D, Valery CA, Bensimon G, et al. A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma. Hum Gene Ther 1998; 9: 2595-2604.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2595-2604
-
-
Klatzmann, D.1
Valery, C.A.2
Bensimon, G.3
-
22
-
-
0034493243
-
Combined antitumor effects of ah adenoviral cytosine deaminase/thymidine kinase fusion gene in rat C6 glioma
-
Chang JW, Lee H, Kim E, et al. Combined antitumor effects of ah adenoviral cytosine deaminase/thymidine kinase fusion gene in rat C6 glioma. Neurosurgery 2000; 47: 931-938.
-
(2000)
Neurosurgery
, vol.47
, pp. 931-938
-
-
Chang, J.W.1
Lee, H.2
Kim, E.3
-
23
-
-
0036262606
-
Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model
-
Moriuchi S, Wolfe D, Tamura M, et al. Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model. Gene Ther 2002; 9: 584-591.
-
(2002)
Gene Ther.
, vol.9
, pp. 584-591
-
-
Moriuchi, S.1
Wolfe, D.2
Tamura, M.3
-
24
-
-
0034660858
-
In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene
-
Erbs P, Regulier E, Kintz J, et al. In vivo cancer gene therapy by adenovirus-mediated transfer of a bifunctional yeast cytosine deaminase/uracil phosphoribosyltransferase fusion gene. Cancer Res 2000; 60: 3813-3822.
-
(2000)
Cancer Res.
, vol.60
, pp. 3813-3822
-
-
Erbs, P.1
Regulier, E.2
Kintz, J.3
-
25
-
-
0028108469
-
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene; significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase
-
Huber BE, Austin EA, Richards CA, et al. Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene; significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase. Proc Natl Acad Sci U S A 1994; 91: 8302-8306.
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 8302-8306
-
-
Huber, B.E.1
Austin, E.A.2
Richards, C.A.3
-
26
-
-
0030724139
-
Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes
-
Denning C, Pitts JD. Bystander effects of different enzyme-prodrug systems for cancer gene therapy depend on different pathways for intercellular transfer of toxic metabolites, a factor that will govern clinical choice of appropriate regimes. Hum Gene Ther 1997; 8: 1825-1835.
-
(1997)
Hum. Gene Ther.
, vol.8
, pp. 1825-1835
-
-
Denning, C.1
Pitts, J.D.2
-
27
-
-
0027483695
-
The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified
-
Freeman SM, Abboud CN, Whatenby KA, et al. The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 1993; 53: 5274-5283.
-
(1993)
Cancer Res.
, vol.53
, pp. 5274-5283
-
-
Freeman, S.M.1
Abboud, C.N.2
Whatenby, K.A.3
-
28
-
-
0031803611
-
Selective in vivo radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells transduced with the E. coli cytosine deaminase (CD) gene
-
Gabel M, Kim JH, Kolozsvary A, et al. Selective in vivo radiosensitization by 5-fluorocytosine of human colorectal carcinoma cells transduced with the E. coli cytosine deaminase (CD) gene. Int J Radiat Oncol Biol Phys 1998; 41: 883-887.
-
(1998)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.41
, pp. 883-887
-
-
Gabel, M.1
Kim, J.H.2
Kolozsvary, A.3
-
29
-
-
0003303340
-
Selective radiosensitization of 9L glioma in the brain transduced with double suicide fusion gene
-
Kim JH, Kolozsvary A, Rogulski K, et al. Selective radiosensitization of 9L glioma in the brain transduced with double suicide fusion gene. Cancer J Sci Am 1998; 4: 364-369.
-
(1998)
Cancer J. Sci. Am.
, vol.4
, pp. 364-369
-
-
Kim, J.H.1
Kolozsvary, A.2
Rogulski, K.3
-
30
-
-
0035893397
-
Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase
-
Nanda D, Vogels R, Havenga M, et al. Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase. Cancer Res 2001; 61: 8743-8750.
-
(2001)
Cancer Res.
, vol.61
, pp. 8743-8750
-
-
Nanda, D.1
Vogels, R.2
Havenga, M.3
-
31
-
-
0035878847
-
Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector
-
Ichikawa T, Chiocca EA. Comparative analyses of transgene delivery and expression in tumors inoculated with a replication-conditional or -defective viral vector. Cancer Res 2001; 61: 5336-5339.
-
(2001)
Cancer Res.
, vol.61
, pp. 5336-5339
-
-
Ichikawa, T.1
Chiocca, E.A.2
|