β-secretase-cleaved amyloid precursor protein accumulates at actin inclusions induced in neurons by stress or amyloid β: A feedforward mechanism for alzheimer's disease

Journal of Neuroscience

Volumn 25, Issue 49, 2005, Pages 11313-11321

  Maloney, Michael T ^a   Minamide, Laurie S ^a   Kinley, Andrew W ^a   Boyle, Judith A ^a   Bamburg, James R ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Actin; ADF cofilin; Alzheimer's disease; Amyloid ; APP processing; Neurite inclusions; Transport

Indexed keywords

ACTIN; ACTIN DEPOLYMERIZING FACTOR; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; COFILIN; GAMMA SECRETASE; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CARBOXY TERMINAL SEQUENCE; CELL STRUCTURE; CELL VACUOLE; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; RAT; SENILE PLAQUE; STRESS; TRANSGENIC MOUSE;

ACTINS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; FEEDBACK, BIOCHEMICAL; HYDROLYSIS; INCLUSION BODIES; MICE; MICE, TRANSGENIC; NEURONS; PEPTIDE FRAGMENTS; RATS; STRESS; XENOPUS;

EID: 30544447666     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3711-05.2005     Document Type: Article

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