Evidence that insulin-like growth factor-1 requires protein kinase C-ε, PI3-kinase and mitogen-activated protein kinase pathways to protect human vascular smooth muscle cells from apoptosis

Immunology and Cell Biology

Volumn 83, Issue 6, 2005, Pages 651-667

  Allen, Todd R ^a   Krueger, Kristopher D ^a   Hunter III, William J ^a   Agrawal, Devendra K ^a  

^a CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Atherosclerosis; c myc; Insulin like growth factor (IGF) 1; Restenosis; Staurosporine

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DNA FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLSERINE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ZETA; PROTEIN KINASE INHIBITOR; PROTEIN STAU; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C; STAUROSPORINE; UNCLASSIFIED DRUG; UO 126; WORTMANNIN;

APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CELL FRACTIONATION; CELL GROWTH; CELL MIGRATION; CONTROLLED STUDY; DATA ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; IMMUNOBLOTTING; NICK END LABELING; NONHUMAN; ONCOGENE C MYC; POLYACRYLAMIDE GEL ELECTROPHORESIS; RAT; RESTENOSIS; SCANNING TRANSMISSION ELECTRON MICROSCOPY; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL SHAPE; CELLS, CULTURED; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MAP KINASE SIGNALING SYSTEM; MICROSCOPY, ELECTRON, SCANNING; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE C-EPSILON; STAUROSPORINE;

EID: 30544442525     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1711.2005.01387.x     Document Type: Article

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