The selective protein kinase C inhibitor, Ro-31-8220, inhibits mitogen- activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression, and activates Jun N-terminal kinase

Journal of Biological Chemistry

Volumn 271, Issue 43, 1996, Pages 27018-27024

  Beltman, Jerlyn ^a   McCormick, Frank ^a   Cook, Simon J ^a  

^a ONYX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PHORBOL ESTER; PHOSPHATASE; PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL CYCLE PROTEINS; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; IMMEDIATE-EARLY PROTEINS; INDOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALEIMIDES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS;

ANIMALIA;

EID: 0029861463     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.43.27018     Document Type: Article

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