-
1
-
-
0038320035
-
Apo2L⧸TRAIL: Apoptosis signaling, biology, and potential for cancer therapy
-
A Almasan A Ashkenazi Apo2L⧸TRAIL: Apoptosis signaling, biology, and potential for cancer therapy Cytokine Growth Factor Rev. 14 2003 337 348
-
(2003)
Cytokine Growth Factor Rev.
, vol.14
, pp. 337-348
-
-
Almasan, A1
Ashkenazi, A2
-
2
-
-
0036598992
-
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
-
A Ashkenazi Targeting death and decoy receptors of the tumour-necrosis factor superfamily Nat. Rev. Cancer 2 2002 420 430
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 420-430
-
-
Ashkenazi, A1
-
3
-
-
0032713075
-
Safety and antitumor activity of recombinant soluble Apo2 ligand
-
A Ashkenazi R.C Pai S Fong S Leung D.A Lawrence S.A Marsters C Blackie L Chang A.E McMurtrey A Hebert L DeForge I.L Koumenis D Lewis L Harris J Bussiere H Koeppen Z Shahrokh R.H Schwall Safety and antitumor activity of recombinant soluble Apo2 ligand J. Clin. Invest. 104 1999 155 162
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 155-162
-
-
Ashkenazi, A1
Pai, R.C2
Fong, S3
Leung, S4
Lawrence, D.A5
Marsters, S.A6
Blackie, C7
Chang, L8
McMurtrey, A.E9
Hebert, A10
DeForge, L11
Koumenis, I.L12
Lewis, D13
Harris, L14
Bussiere, J15
Koeppen, H16
Shahrokh, Z17
Schwall, R.H18
-
4
-
-
0027211704
-
Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation
-
D.W Banner A D'Arcy W Janes R Gentz H.J Schoenfeld C Broger H Loetscher W Lesslauer Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: Implications for TNF receptor activation Cell 73 1993 431 445
-
(1993)
Cell
, vol.73
, pp. 431-445
-
-
Banner, D.W1
D'Arcy, A2
Janes, W3
Gentz, R4
Schoenfeld, H.J5
Broger, C6
Loetscher, H7
Lesslauer, W8
-
5
-
-
0034617304
-
Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL
-
J.L Bodmer P Meier J Tschopp P Schneider Cysteine 230 is essential for the structure and activity of the cytotoxic ligand TRAIL J. Biol. Chem. 275 2000 20632 20637
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20632-20637
-
-
Bodmer, J.L1
Meier, P2
Tschopp, J3
Schneider, P4
-
7
-
-
0031914977
-
High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity
-
S.S Cha J.S Kim H.S Cho N.K Shin W Jeong H.C Shin Y.J Kim J.H Hahn B.-H Oh High resolution crystal structure of a human tumor necrosis factor-alpha mutant with low systemic toxicity J. Biol. Chem. 273 1998 2153 2160
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2153-2160
-
-
Cha, S.S1
Kim, J.S2
Cho, H.S3
Shin, N.K4
Jeong, W5
Shin, H.C6
Kim, Y.J7
Hahn, J.H8
Oh, B.-H9
-
8
-
-
0033169230
-
2.8 Å resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity
-
S.S Cha M.S Kim Y.H Choi B.J Sung N.K Shin H.C Shin Y.C Sung B.H Oh 2.8 Å resolution crystal structure of human TRAIL, a cytokine with selective antitumor activity Immunity 11 1999 253 261
-
(1999)
Immunity
, vol.11
, pp. 253-261
-
-
Cha, S.S1
Kim, M.S2
Choi, Y.H3
Sung, B.J4
Shin, N.K5
Shin, H.C6
Sung, Y.C7
Oh, B.H8
-
9
-
-
0034613295
-
Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity
-
S.S Cha B.J Sung Y.A Kim Y.L Song H.J Kim S Kim M.S Lee B.H Oh Crystal structure of TRAIL-DR5 complex identifies a critical role of the unique frame insertion in conferring recognition specificity J. Biol. Chem. 275 2000 31171 31177
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31171-31177
-
-
Cha, S.S1
Sung, B.J2
Kim, Y.A3
Song, Y.L4
Kim, H.J5
Kim, S6
Lee, M.S7
Oh, B.H8
-
10
-
-
0036467427
-
Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
-
E Cretney K Takeda H Yagita M Glaccum J.J Peschon M.J Smyth Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice J. Immunol. 168 2002 1356 1361
-
(2002)
J. Immunol.
, vol.168
, pp. 1356-1361
-
-
Cretney, E1
Takeda, K2
Yagita, H3
Glaccum, M4
Peschon, J.J5
Smyth, M.J6
-
11
-
-
0031414749
-
The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
-
M.A Degli-Esposti W.C Dougall P.J Smolak J.Y Waugh C.A Smith R.G Goodwin The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain Immunity 7 1997 813 820
-
(1997)
Immunity
, vol.7
, pp. 813-820
-
-
Degli-Esposti, M.A1
Dougall, W.C2
Smolak, P.J3
Waugh, J.Y4
Smith, C.A5
Goodwin, R.G6
-
12
-
-
0030869432
-
Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
-
M.A Degli-Esposti P.J Smolak H Walczak J Waugh C.P Huang R.F DuBose R.G Goodwin C.A Smith Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family J. Exp. Med. 186 1997 1165 1170
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1165-1170
-
-
Degli-Esposti, M.A1
Smolak, P.J2
Walczak, H3
Waugh, J4
Huang, C.P5
DuBose, R.F6
Goodwin, R.G7
Smith, C.A8
-
13
-
-
0024357657
-
The structure of tumor necrosis factor-alpha at 2.6 Å resolution. Implications for receptor binding
-
M.J Eck S.R Sprang The structure of tumor necrosis factor-alpha at 2.6 Å resolution. Implications for receptor binding J. Biol. Chem. 264 1989 17595 17605
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 17595-17605
-
-
Eck, M.J1
Sprang, S.R2
-
14
-
-
0026787018
-
The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution
-
M.J Eck M Ultsch E Rinderknecht A.M de Vos S.R Sprang The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution J. Biol. Chem. 267 1992 2119 2122
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2119-2122
-
-
Eck, M.J1
Ultsch, M2
Rinderknecht, E3
de Vos, A.M4
Sprang, S.R5
-
15
-
-
7344233085
-
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
-
J.G Emery P McDonnell M.B Burke K.C Deen S Lyn C Silverman E Dul E.R Appelbaum C Eichman R DiPrinzio R.A Dodds I.E James M Rosenberg J.C Lee P.R Young Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL J. Biol. Chem. 273 1998 14363 14367
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14363-14367
-
-
Emery, J.G1
McDonnell, P2
Burke, M.B3
Deen, K.C4
Lyn, S5
Silverman, C6
Dul, E7
Appelbaum, E.R8
Eichman, C9
DiPrinzio, R10
Dodds, R.A11
James, I.E12
Rosenberg, M13
Lee, J.C14
Young, P.R15
-
16
-
-
0037846097
-
BAFF⧸BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
-
N.C Gordon B Pan S.G Hymowitz J Yin R.F Kelley A.G Cochran M Yan V.M Dixit W.J Fairbrother M.A Starovasnik BAFF⧸BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site Biochemistry 42 2003 5977 5983
-
(2003)
Biochemistry
, vol.42
, pp. 5977-5983
-
-
Gordon, N.C1
Pan, B2
Hymowitz, S.G3
Yin, J4
Kelley, R.F5
Cochran, A.G6
Yan, M7
Dixit, V.M8
Fairbrother, W.J9
Starovasnik, M.A10
-
17
-
-
0031782909
-
TRAIL: A molecule with multiple receptors and control mechanisms
-
T.S Griffith D.H Lynch TRAIL: A molecule with multiple receptors and control mechanisms Curr. Opin. Immunol. 10 1998 559 563
-
(1998)
Curr. Opin. Immunol.
, vol.10
, pp. 559-563
-
-
Griffith, T.S1
Lynch, D.H2
-
18
-
-
0037086077
-
Osteoprotegerin (OPG) is a survival factor for human prostate cancer cell
-
I Holen P.I Croucher F.C Hamdy C.L Eaton Osteoprotegerin (OPG) is a survival factor for human prostate cancer cell Cancer Res. 62 2002 1619 1623
-
(2002)
Cancer Res.
, vol.62
, pp. 1619-1623
-
-
Holen, I1
Croucher, P.I2
Hamdy, F.C3
Eaton, C.L4
-
19
-
-
0033212968
-
Triggering cell death: The crystal structure of Apo2L⧸TRAIL in a complex with death receptor 5
-
S.G Hymowitz H.W Christinger G Fuh M Ultsch M O'Connell R.F Kelley A Ashkenazi A.M de Vos Triggering cell death: The crystal structure of Apo2L⧸TRAIL in a complex with death receptor 5 Mol. Cell 4 1999 563 571
-
(1999)
Mol. Cell
, vol.4
, pp. 563-571
-
-
Hymowitz, S.G1
Christinger, H.W2
Fuh, G3
Ultsch, M4
O'Connell, M5
Kelley, R.F6
Ashkenazi, A7
de Vos, A.M8
-
20
-
-
0034142219
-
A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L⧸TRAIL
-
S.G Hymowitz M.P O'Connell M.H Ultsch A Hurst K Totpal A Ashkenazi A.M de Vos R.F Kelley A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L⧸TRAIL Biochemistry 39 2000 633 640
-
(2000)
Biochemistry
, vol.39
, pp. 633-640
-
-
Hymowitz, S.G1
O'Connell, M.P2
Ultsch, M.H3
Hurst, A4
Totpal, K5
Ashkenazi, A6
de Vos, A.M7
Kelley, R.F8
-
21
-
-
0037155157
-
Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution
-
S Ito K Wakabayashi O Ubukata S Hayashi F Okada T Hata Crystal structure of the extracellular domain of mouse RANK ligand at 2.2-A resolution J. Biol. Chem. 277 2002 6631 6636
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6631-6636
-
-
Ito, S1
Wakabayashi, K2
Ubukata, O3
Hayashi, S4
Okada, F5
Hata, T6
-
22
-
-
0034022160
-
Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
-
M Jo T.H Kim D.W Seol J.E Esplen K Dorko T.R Billiar S.C Strom Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand Nat. Med. 6 2000 564 567
-
(2000)
Nat. Med.
, vol.6
, pp. 564-567
-
-
Jo, M1
Kim, T.H2
Seol, D.W3
Esplen, J.E4
Dorko, K5
Billiar, T.R6
Strom, S.C7
-
23
-
-
0024539057
-
Structure of tumour necrosis factor
-
E.Y Jones D.I Stuart N.P Walker Structure of tumour necrosis factor Nature 338 1989 225 228
-
(1989)
Nature
, vol.338
, pp. 225-228
-
-
Jones, E.Y1
Stuart, D.I2
Walker, N.P3
-
24
-
-
0036300545
-
Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes
-
M Karpusas T.G Cachero F Qian A Boriack-Sjodin C Mullen K Strauch Y.M Hsu S.L Kalled Crystal structure of extracellular human BAFF, a TNF family member that stimulates B lymphocytes J. Mol. Biol. 15 2002 1145 1154
-
(2002)
J. Mol. Biol.
, vol.15
, pp. 1145-1154
-
-
Karpusas, M1
Cachero, T.G2
Qian, F3
Boriack-Sjodin, A4
Mullen, C5
Strauch, K6
Hsu, Y.M7
Kalled, S.L8
-
26
-
-
0242684718
-
Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation
-
H.M Kim K.S Yu M.E Lee D.R Shin Y.S Kim S.G Paik O.J Yoo H Lee J.O Lee Crystal structure of the BAFF-BAFF-R complex and its implications for receptor activation Nat. Struct. Biol. 10 2003 342 348
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 342-348
-
-
Kim, H.M1
Yu, K.S2
Lee, M.E3
Shin, D.R4
Kim, Y.S5
Paik, S.G6
Yoo, O.J7
Lee, H8
Lee, J.O9
-
28
-
-
0034784606
-
Crystal structure of the TRANCE⧸RANKL cytokine reveals determinants of receptor-ligand specificity
-
J Lam C.A Nelson F.P Ross S.L Teitelbaum D.H Fremont Crystal structure of the TRANCE⧸RANKL cytokine reveals determinants of receptor-ligand specificity J. Clin. Invest. 108 2001 971 979
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 971-979
-
-
Lam, J1
Nelson, C.A2
Ross, F.P3
Teitelbaum, S.L4
Fremont, D.H5
-
29
-
-
0035050960
-
Differential hepatocyte toxicity of recombinant Apo2L⧸TRAIL versions
-
D Lawrence Z Shahrokh S Marsters K Achilles D Shih B Mounho K Hillan K Totpal L DeForge P Schow J Hooley S Sherwood R Pai S Leung L Khan B Gliniak J Bussiere C.A Smith S.S Strom S Kelley J.A Fox D Thomas A Ashkenazi Differential hepatocyte toxicity of recombinant Apo2L⧸TRAIL versions Nat. Med. 7 2001 383 385
-
(2001)
Nat. Med.
, vol.7
, pp. 383-385
-
-
Lawrence, D1
Shahrokh, Z2
Marsters, S3
Achilles, K4
Shih, D5
Mounho, B6
Hillan, K7
Totpal, K8
DeForge, L9
Schow, P10
Hooley, J11
Sherwood, S12
Pai, R13
Leung, S14
Khan, L15
Gliniak, B16
Bussiere, J17
Smith, C.A18
Strom, S.S19
Kelley, S20
Fox, J.A21
Thomas, D22
Ashkenazi, A23
more..
-
30
-
-
0037273848
-
Apo2L⧸TRAIL and its death and decoy receptors
-
H.N LeBlanc A Ashkenazi Apo2L⧸TRAIL and its death and decoy receptors Cell Death Differ. 10 2003 66 75
-
(2003)
Cell Death Differ.
, vol.10
, pp. 66-75
-
-
LeBlanc, H.N1
Ashkenazi, A2
-
31
-
-
0034776231
-
TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy
-
L.F Lincz T.X Yeh A Spencer TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy Leukemia 15 2001 1650 1657
-
(2001)
Leukemia
, vol.15
, pp. 1650-1657
-
-
Lincz, L.F1
Yeh, T.X2
Spencer, A3
-
32
-
-
0038076049
-
Ligand-receptor binding revealed by the TNF family member TALL-1
-
Y Liu X Hong J Kappler L Jiang R Zhang L Xu C.H Pan W.E Martin R.C Murphy H.B Shu S Dai G Zhang Ligand-receptor binding revealed by the TNF family member TALL-1 Nature 423 2003 49 56
-
(2003)
Nature
, vol.423
, pp. 49-56
-
-
Liu, Y1
Hong, X2
Kappler, J3
Jiang, L4
Zhang, R5
Xu, L6
Pan, C.H7
Martin, W.E8
Murphy, R.C9
Shu, H.B10
Dai, S11
Zhang, G12
-
33
-
-
0036183318
-
Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands
-
Y Liu L Xu N Opalka J Kappler H.B Shu G Zhang Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands Cell 108 2002 383 394
-
(2002)
Cell
, vol.108
, pp. 383-394
-
-
Liu, Y1
Xu, L2
Opalka, N3
Kappler, J4
Shu, H.B5
Zhang, G6
-
34
-
-
0035936797
-
The TNF and TNF receptor superfamilies: Integrating mammalian biology
-
R.M Locksley N Killeen M.J Lenardo The TNF and TNF receptor superfamilies: Integrating mammalian biology Cell 104 2001 487 501
-
(2001)
Cell
, vol.104
, pp. 487-501
-
-
Locksley, R.M1
Killeen, N2
Lenardo, M.J3
-
35
-
-
13144265771
-
A novel receptor for Apo2L⧸TRAIL contains a truncated death domain
-
S.A Marsters J.P Sheridan R.M Pitti A Huang M Skubatch D Baldwin J Yuan A Gurney A.D Goddard P Godowski A Ashkenazi A novel receptor for Apo2L⧸TRAIL contains a truncated death domain Curr. Biol. 7 1997 1003 1006
-
(1997)
Curr. Biol.
, vol.7
, pp. 1003-1006
-
-
Marsters, S.A1
Sheridan, J.P2
Pitti, R.M3
Huang, A4
Skubatch, M5
Baldwin, D6
Yuan, J7
Gurney, A8
Goddard, A.D9
Godowski, P10
Ashkenazi, A11
-
36
-
-
0031627483
-
Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): A new receptor protecting lymphocytes from the death ligand TRAIL
-
J Mongkolsapaya A.E Cowper X.N Xu G Morris A.J McMichael J.I Bell G.R Screaton Lymphocyte inhibitor of TRAIL (TNF-related apoptosis-inducing ligand): A new receptor protecting lymphocytes from the death ligand TRAIL J. Immunol. 160 1998 3 6
-
(1998)
J. Immunol.
, vol.160
, pp. 3-6
-
-
Mongkolsapaya, J1
Cowper, A.E2
Xu, X.N3
Morris, G4
McMichael, A.J5
Bell, J.I6
Screaton, G.R7
-
38
-
-
0030589099
-
Structures of the extracellular domain of the type I tumor necrosis factor receptor
-
J.H Naismith T.Q Devine T Kohno S.R Sprang Structures of the extracellular domain of the type I tumor necrosis factor receptor Structure 4 1996 1251 1262
-
(1996)
Structure
, vol.4
, pp. 1251-1262
-
-
Naismith, J.H1
Devine, T.Q2
Kohno, T3
Sprang, S.R4
-
39
-
-
0036221083
-
Structural basis of BLyS receptor recognition
-
D.A Oren Y Li Y Volovik T.S Morris C Dharia K Das O Galperina R Gentz E Arnold Structural basis of BLyS receptor recognition Nat. Struct. Biol. 9 2002 288 292
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 288-292
-
-
Oren, D.A1
Li, Y2
Volovik, Y3
Morris, T.S4
Dharia, C5
Das, K6
Galperina, O7
Gentz, R8
Arnold, E9
-
40
-
-
0030762815
-
An antagonist decoy receptor and a death domain-containing receptor for TRAIL
-
G Pan J Ni Y.F Wei G Yu R Gentz V.M Dixit An antagonist decoy receptor and a death domain-containing receptor for TRAIL Science 277 1997 815 818
-
(1997)
Science
, vol.277
, pp. 815-818
-
-
Pan, G1
Ni, J2
Wei, Y.F3
Yu, G4
Gentz, R5
Dixit, V.M6
-
42
-
-
17544367410
-
Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
-
R.M Pitti S.A Marsters S Ruppert C.J Donahue A Moore A Ashkenazi Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family J. Biol. Chem. 271 1996 12687 12690
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 12687-12690
-
-
Pitti, R.M1
Marsters, S.A2
Ruppert, S3
Donahue, C.J4
Moore, A5
Ashkenazi, A6
-
43
-
-
0029098546
-
Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions
-
M Schuchmann S Hess P Bufler C Brakebusch D Wallach A Porter G Riethmuller H Engelmann Functional discrepancies between tumor necrosis factor and lymphotoxin alpha explained by trimer stability and distinct receptor interactions Eur. J. Immunol. 25 1995 2183 2189
-
(1995)
Eur. J. Immunol.
, vol.25
, pp. 2183-2189
-
-
Schuchmann, M1
Hess, S2
Bufler, P3
Brakebusch, C4
Wallach, D5
Porter, A6
Riethmuller, G7
Engelmann, H8
-
44
-
-
0036687185
-
Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL⧸Apo2L, using TRAIL⧸Apo2L gene-deficient mice
-
L.M Sedger M.B Glaccum J.C Schuh S.T Kanaly E Williamson N Kayagaki T Yun P Smolak T Le R Goodwin B Gliniak Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL⧸Apo2L, using TRAIL⧸Apo2L gene-deficient mice Eur. J. Immunol. 32 2002 2246 2254
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2246-2254
-
-
Sedger, L.M1
Glaccum, M.B2
Schuh, J.C3
Kanaly, S.T4
Williamson, E5
Kayagaki, N6
Yun, T7
Smolak, P8
Le, T9
Goodwin, R10
Gliniak, B11
-
45
-
-
0033565590
-
IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression
-
L.M Sedger D.M Shows R.A Blanton J.J Peschon R.G Goodwin D Cosman S.R Wiley IFN-gamma mediates a novel antiviral activity through dynamic modulation of TRAIL and TRAIL receptor expression J. Immunol. 163 1999 920 926
-
(1999)
J. Immunol.
, vol.163
, pp. 920-926
-
-
Sedger, L.M1
Shows, D.M2
Blanton, R.A3
Peschon, J.J4
Goodwin, R.G5
Cosman, D6
Wiley, S.R7
-
46
-
-
0034123874
-
Cysteine 230 modulates tumor necrosis factor-related apoptosis-inducing ligand activity
-
D.W Seol T.R Billiar Cysteine 230 modulates tumor necrosis factor-related apoptosis-inducing ligand activity Cancer Res. 60 2000 3152 3154
-
(2000)
Cancer Res.
, vol.60
, pp. 3152-3154
-
-
Seol, D.W1
Billiar, T.R2
-
47
-
-
0030792712
-
Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
-
J.P Sheridan S.A Marsters R.M Pitti A Gurney M Skubatch D Baldwin L Ramakrishnan C.L Gray K Baker W.I Wood A.D Goddard P Godowski A Ashkenazi Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors Science 277 1997 818 821
-
(1997)
Science
, vol.277
, pp. 818-821
-
-
Sheridan, J.P1
Marsters, S.A2
Pitti, R.M3
Gurney, A4
Skubatch, M5
Baldwin, D6
Ramakrishnan, L7
Gray, C.L8
Baker, K9
Wood, W.I10
Goddard, A.D11
Godowski, P12
Ashkenazi, A13
-
48
-
-
0037374460
-
Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand⧸Apo2 ligand and can function as a paracrine survival factor for human myeloma cells
-
C.M Shipman P.I Croucher Osteoprotegerin is a soluble decoy receptor for tumor necrosis factor-related apoptosis-inducing ligand⧸Apo2 ligand and can function as a paracrine survival factor for human myeloma cells Cancer Res. 63 2003 912 916
-
(2003)
Cancer Res.
, vol.63
, pp. 912-916
-
-
Shipman, C.M1
Croucher, P.I2
-
49
-
-
0031005576
-
Osteoprotegerin: A novel secreted protein involved in the regulation of bone density
-
W.S Simonet D.L Lacey C.R Dunstan M Kelley M.S Chang R Luthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van J Tarpley P Derby R Lee W.J Boyle Osteoprotegerin: A novel secreted protein involved in the regulation of bone density Cell 89 1997 309 319
-
(1997)
Cell
, vol.89
, pp. 309-319
-
-
Simonet, W.S1
Lacey, D.L2
Dunstan, C.R3
Kelley, M4
Chang, M.S5
Luthy, R6
Nguyen, H.Q7
Wooden, S8
Bennett, L9
Boone, T10
Shimamoto, G11
DeRose, M12
Elliott, R13
Colombero, A14
Tan, H.L15
Trail, G16
Sullivan, J17
Davy, E18
Bucay, N19
Renshaw-Gegg, L20
Hughes, T.M21
Hill, D22
Pattison, W23
Campbell, P24
Sander, S25
Van, G26
Tarpley, J27
Derby, P28
Lee, R29
Boyle, W.J30
more..
-
50
-
-
0037009370
-
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
-
M.R Sprick E Rieser H Stahl A Grosse-Wilde M.A Weigand H Walczak Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8 EMBO J. 21 2002 4520 4530
-
(2002)
EMBO J.
, vol.21
, pp. 4520-4530
-
-
Sprick, M.R1
Rieser, E2
Stahl, H3
Grosse-Wilde, A4
Weigand, M.A5
Walczak, H6
-
51
-
-
0033667778
-
FADD⧸MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2
-
M.R Sprick M.A Weigand E Rieser C.T Rauch P Juo J Blenis P.H Krammer H Walczak FADD⧸MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 Immunity 12 2000 599 609
-
(2000)
Immunity
, vol.12
, pp. 599-609
-
-
Sprick, M.R1
Weigand, M.A2
Rieser, E3
Rauch, C.T4
Juo, P5
Blenis, J6
Krammer, P.H7
Walczak, H8
-
52
-
-
0035137696
-
Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
-
K Takeda Y Hayakawa M.J Smyth N Kayagaki N Yamaguchi S Kakuta Y Iwakura H Yagita K Okumura Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells Nat. Med. 7 2001 94 100
-
(2001)
Nat. Med.
, vol.7
, pp. 94-100
-
-
Takeda, K1
Hayakawa, Y2
Smyth, M.J3
Kayagaki, N4
Yamaguchi, N5
Kakuta, S6
Iwakura, Y7
Yagita, H8
Okumura, K9
-
53
-
-
0037148518
-
Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development
-
K Takeda M.J Smyth E Cretney Y Hayakawa N Kayagaki H Yagita K Okumura Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development J. Exp. Med. 195 2002 161 169
-
(2002)
J. Exp. Med.
, vol.195
, pp. 161-169
-
-
Takeda, K1
Smyth, M.J2
Cretney, E3
Hayakawa, Y4
Kayagaki, N5
Yagita, H6
Okumura, K7
-
54
-
-
0034283184
-
Functional analysis of tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL): Cysteine-230 plays a critical role in the homotrimerization and biological activity of this novel tumoricidal cytokine
-
D Trabzuni K.S Famulski M Ahmad Functional analysis of tumour necrosis factor-alpha-related apoptosis-inducing ligand (TRAIL): Cysteine-230 plays a critical role in the homotrimerization and biological activity of this novel tumoricidal cytokine Biochem. J. 350 2000 505 510
-
(2000)
Biochem. J.
, vol.350
, pp. 505-510
-
-
Trabzuni, D1
Famulski, K.S2
Ahmad, M3
-
55
-
-
0034725664
-
Temperature-sensitive differential affinity of TRAIL for its receptors: DR5 is the highest affinity receptor
-
A Truneh S Sharma C Silverman S Khandekar M.P Reddy K.C Deen M.M McLaughlin S.M Srinivasula G.P Livi L.A Marshall E.S Alnemri W.V Williams M.L Doyle Temperature-sensitive differential affinity of TRAIL for its receptors: DR5 is the highest affinity receptor J. Biol. Chem. 275 2000 23319 23325
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23319-23325
-
-
Truneh, A1
Sharma, S2
Silverman, C3
Khandekar, S4
Reddy, M.P5
Deen, K.C6
McLaughlin, M.M7
Srinivasula, S.M8
Livi, G.P9
Marshall, L.A10
Alnemri, E.S11
Williams, W.V12
Doyle, M.L13
-
56
-
-
0030880548
-
TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
-
H Walczak M.A Degli-Esposti R.S Johnson P.J Smolak J.Y Waugh N Boiani M.S Timour M.J Gerhart K.A Schooley C.A Smith R.G Goodwin C.T Rauch TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL EMBO J. 16 1997 5386 5397
-
(1997)
EMBO J.
, vol.16
, pp. 5386-5397
-
-
Walczak, H1
Degli-Esposti, M.A2
Johnson, R.S3
Smolak, P.J4
Waugh, J.Y5
Boiani, N6
Timour, M.S7
Gerhart, M.J8
Schooley, K.A9
Smith, C.A10
Goodwin, R.G11
Rauch, C.T12
-
57
-
-
0032929520
-
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
-
H Walczak R.E Miller K Ariail B Gliniak T.S Griffith M Kubin W Chin J Jones A Woodward T Le C Smith P Smolak R.G Goodwin C.T Rauch J.C Schuh D.H Lynch Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo Nat. Med. 5 1999 157 163
-
(1999)
Nat. Med.
, vol.5
, pp. 157-163
-
-
Walczak, H1
Miller, R.E2
Ariail, K3
Gliniak, B4
Griffith, T.S5
Kubin, M6
Chin, W7
Jones, J8
Woodward, A9
Le, T10
Smith, C11
Smolak, P12
Goodwin, R.G13
Rauch, C.T14
Schuh, J.C15
Lynch, D.H16
-
58
-
-
13344285339
-
Identification and characterization of a new member of the TNF family that induces apoptosis
-
S.R Wiley K Schooley P.J Smolak W.S Din C.P Huang J.K Nicholl G.R Sutherland T.D Smith C Rauch C.A Smith Identification and characterization of a new member of the TNF family that induces apoptosis Immunity 3 1995 673 682
-
(1995)
Immunity
, vol.3
, pp. 673-682
-
-
Wiley, S.R1
Schooley, K2
Smolak, P.J3
Din, W.S4
Huang, C.P5
Nicholl, J.K6
Sutherland, G.R7
Smith, T.D8
Rauch, C9
Smith, C.A10
|