The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition

BMC Developmental Biology

Volumn 1, Issue , 2001, Pages 1-19

  Melnick, Michael ^a   Chen, Haiming ^a   Zhou, Yan Min ^a   Jaskoll, Tina ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CASPASE 6; CHECKPOINT KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OSTEOGENIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR E2F1;

ANALYTIC METHOD; ANIMAL CELL; APOPTOSIS; ARTICLE; ARTIFICIAL NEURAL NETWORK; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; GENOME ANALYSIS; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PHENOTYPE; PROBABILITY; PROTEIN EXPRESSION; PROTEOMICS; SIGNAL TRANSDUCTION; SUBMANDIBULAR GLAND;

ANIMALIA;

EID: 3042724638     PISSN: 1471213X     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-213X-1-15     Document Type: Article

References (108)

1. Ball WD: Development of the rat salivary glands. III. Mesenchymal specificity in the morphogenesis of the embryonic submaxillary and sublingual glands of the rat. J Exp Zool 1974, 188:277-288
2. Cutler LS, Gremski W: Epithelial-mesenchymal interactions in the development of salivary glands. Crit Rev Oral Biol Med 1991, 2:1-12
3. Denny PC, Ball WD, Redman RS: Salivary glands: a paradigm for diversity of gland development. Crit Rev Oral Biol Med 1997, 8:51-75
4. Gresik EW, Kashimata M, Kadoya Y, Yamashina S: The EGF system in fetal development. Eur J Morphol 1998, 36 (Suppl):92-97
5. Jaskoll T, Chen H, Denny P, Denny P, Melnick M: Mouse submandibular gland mucin: embryo-specific mRNA and protein species. Mech Dev 1998, 74:179-183
6. Kashimata M, Sayeed S, Ka A, Onetti-Muda A, Sakagami H, Faraggiana T, Gresik E: The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF. Dev Biol 2000, 220:183-196
7. Redman RS: Development of the salivary glands. In The Salivary System. Edited by Sreebny LM. Boca Raton: CRC Press 19871-20
8. Wessells N: Tissue interactions and development. Menlo Park: Benjamin Cummins, 1977
9. Jaskoll T, Melnick M: Submandibular gland morphogenesis: stage-specific expression of TGF-alpha, EGF, IGF, TGF-beta, TNF and IL-6 signal transduction in normal mice and the phenotypic effects of TGF-beta2, TGF-beta3, and EGF-R null mutations. Anat Rec 1999, 256:252-268
10. Jaskoll T, Zhou Y-M, Chai Y, Makarenkova HP, Collinson JM, West JD, Lee J, Melnick M: Embryonic submandibular gland morphogenesis: stage-specific protein localization of FGFs, BMPs, Pax6 and Pax9 in normal mice and abnormal SMG phenotypes in FgfR2-IIIc+/Δ, BMP7-/- and Pax6-/- mice. Cells Tiss Org 2002, 270:83-98
11. Kashimata M, Gresik E: Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the α-integrin subunit. Dev Dyn 1997, 208:149-161
12. Melnick M, Jaskoll T: Mouse submandibular gland morphogenesis: a paradigm for embryonic signal processing. Crit Rev Oral Biol 2000, 11:199-215
13. Melnick M, Chen H, Zhou Y-M, Jaskoll T: Embryonic mouse submandibular salivary gland morphogenesis and the TNF/TNF-R1 signal transduction pathway. Anat Rec 2001, 262:318-320
14. Melnick M, Chen H, Zhou Y, Jaskoll T: Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis. Cells Tiss Org 2001, 168:233-245
15. Bhalla U, Iyengar R: Emergent properties of networks of biological signaling pathways. Science 1999, 283:381-386
16. Kauffman SA: The origins of order. New York: Oxford University Press, 1993
17. Kauffman SA: At Home in the Universe. The Search for Laws of Self-Organization and Complexity. New York: Oxford University Press, 1995
18. Jordan JD, Landau EM, Iyengar R: Signaling networks: the origins of cellular multitasking. Cell 2000, 103:193-200
19. Gilbert SF, Sarkar S: Embracing complexity: organicism for the 21st century. Dev Dyn 2000, 219:1-9
20. Palsson B: The challenges of in silico biology. Nature Biotech 2000, 18:1147-1150
21. Smith RD: Probing proteomes-seeing the whole picture? Nature Biotech 2000, 18:1041-1042
22. Streelman JT, Kocher TD: From phenotype to genotype. Evol Dev 2000, 2:166-173
23. Ghosh S: Regulation of inducible gene expression by the transcription factor NF-kappaB. Immunol Res 1999, 19:183-189
24. Maggirwar SB, Sarmiere PD, Dewhurst S, Freeman RS: Nerve growth factor-dependent activation of NFκB contributes to survival of sympathetic neurons. J Neurosci 1998, 18:10356-10365
25. Qin ZH, Chen RW, Wang Y, Nakai M, Chuang DM, Chase TN: Nuclear factor κB nuclear translocation upregulates c-Myc and p53 expression during NADA receptor-mediated apoptosis in rat seriatim. J Neurosci 1999, 19:4023-4033
26. Nishikimi A, Mukai J, Yamada M: Nuclear translocation of nuclear factor kappa B in early 1-cell mouse embryos. Biol Reprod 1999, 60:1536-1541
27. Schmidt-Ullrich R, Memet S, Lilienbaum A, Feuillard J, Raphael M, Israel A: NFκB activity in transgenic mice: developmental regulation and tissue specificity. Development 1996, 122:2117-2128
28. Pahl HL: Activators and target genes of Rel/NFκB transcription factors. Oncogene 1999, 18:6853-6866
29. Perkins ND: Achieving transcriptional specificity with NFκB. Int J Biochem Cell Biol 1997, 29:1433-1448
30. Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS: NFκB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress Caspase-8 activation. Science 1998, 281:1680-1683
31. Webster GA, Perkins ND: Transcriptional crosstalk between NFκB and p53. Mol Cell Biol 1999, 19:3485-3495
32. Pise-Masison CA, Mahieux R, Jiang H, Ashcroft M, Radonivich M, Duvall J, Guillerm C, Brady JN: Inactivation of p53 by Human T-cell lymphotropic virus Type 1 Tax requires activation of the NF-κB pathway and is dependent on p53 phosphorylation. Mol Cell Biol 2000, 20:3377-3386
33. Kolenko V, Bloom T, Rayman P, Bukowski R, Hsi E, Finke J: Inhibition of NFκB activity in human T lymphocytes induces caspase-dependent apoptosis without detectable activation of Caspase-1 and -3. J Immunol 1999, 163:590-598
34. Lin YZ, SY Yao, Veach RA, Torgerson TR, Hawiger J: Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell-membrane permeable motif and nuclear localization sequence. J Biol Chem 1995, 270:14255-14258
35. Liu RY, Fan C, Olashaw NE, Wang X, Zuckerman KS: Tumor necrosis factor-alpha-induced proliferation of human Mo7e leukemic cells occurs via activation of nuclear factor κB transcription factor. J Biol Chem 1998, 274:13877-13885
36. Ashkenazi A, Dixit V: Death receptors: signaling and modulation. Science 1998, 281:1305-1308
37. Li M, Ona VO, Guegan C, Chen M, Jackson-Lewis V, Andrews LJ, Olszewski AJ, Stieg PE, Lee JP, Przedborski S, Friedlander RM: Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science 2000, 288:335-339
38. Monell C: Caspase cascade in apoptosis. Biocarta 2001 [www.biocar-ta.coni/pathfiles/caspasePathway.asp.]
39. Kaltschmidt B, Kaltschmidt C: DNA array analysis of the developing cerebellum: transforming growth factor-β2 inhibits constitutively activated NFκB in granule neurons. Mech Dev 2001, 101:11-19
40. Bitzer M, von Gersdorff G, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, Bottinger EP: A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA Genes Develop 2000, 14:187-197
41. Nagarajan RP, Chen F, Li W, Vig E, Harrington MA, Nakshatri H, Chen Y: Repression of transforming-growth-factor-β-mediated transcription by nuclear factor κB. Biochem J 2000, 348:591-596
42. Lallemand F, Mazars A, Prunier C, Bertrand F, Kornprost M, Gallea S, Roman-Roman S, Cherqui G, Atfi A: Smad7 inhibits the survival nuclear factor κB and potentiates apoptosis in epithelial cells. Oncogene 2001, 20:879-884
43. Tao Y, Williams-Skipp C, Scheinman RI: Mapping of glucocorticoid receptor DNA binding domain surfaces contributing to transrepression of NF-κB and induction of apoptosis. J Biol Chem 2001, 276:2329-2332
44. Doucas V, Shi Y, Miyamoto S, West A, Verma I, Evans RM: Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-κB and the glucocorticoid receptor. Proc Natl Acad Sci (USA) 2000, 97:11893-11898
45. McKay LI, Cidlowski JA: CBP (CREB Binding Protein) integrates NF-κB (Nuclear Factor-κB) and glucocorticoid receptor physical interactions and antagonism. Mol End 2000, 14:1222-1234
46. Nissen RM, Yamamoto KR: The glucocorticoid receptor inhibits NFκB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev 2000, 14:2314-2329
47. Wissink S, van Hairdo EC, vanned der Burg B, van der SAA PT: A dual mechanism mediates repression of NF-kappa B activity by glucocorticoids. Mol Endocr 1998, 12:355-363
48. Gygi SP, Rochan Y, Franza BR, Aebersold R: Correlation between protein and mRNA abundance in yeast. Mol Cell Biol 1999, 19:1720-1730
49. DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR: Distinct roles of E2F proteins in cell growth control including a unique role for the E2F1 protein as a signal as apoptosis. Proc Natl Acad Sci USA 1997, 94:7245-7250
50. Marzio G, Wagener C, Gutierrez MI, Cartwright P, Helin K, Giacca M: E2F family members are differentially regulated by reversible acetylation. J Biol Chem 2000, 275:10887-92
51. Irwin M, Marin MC, Phillips AC, et al: Role for the p53 homologue p73 in E2F1-induced apoptosis. Nature 2000, 407:645-648
52. Yang HL, Dong YB, Elliott MJ, Liu TJ, McMasters KM: Caspase activation and changes in Bcl-2 family member protein expression associated with E2F1-mediated apoptosis in human esophageal cancer cells. Clin Can Res 2000, 6:1579-1589
53. Yamasaki L, Jacks T, Bronson R, Goillot E, Harlow E, Dyson NJ: Tumor induction and tissue atrophy in mice lacking E2F1. Cell 1996, 85:537-548
54. Lillibridge CD, O'Connell BC: In human salivary gland cells, overexpression of E2F1 overcomes an Interferon-γ- and Tumor Necrosis factor-α-induced growth arrest but does not result in complete mitosis. J Cell Physiol 1997, 172:343-350
55. Van de Craen M, Declercq W, Van den brande I, Fiers W, Vandenabeele P: The proteolytic procaspase activation network: an in vitro analysis. Cell Death Differ 1999, 6:1117-24
56. Chu K, Niu X, Williams L: A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis. Proc Natl Acad Sci (USA) 1995, 92:11894-11898
57. O'Dell W: Fas signaling pathway. Biocarta 2001 [www.biocar-ta.com/ pathfiles/fasPathway.asp]
58. Tran SEF, Holmstrom TH, Ahonen M, Kahari V-M, Eriksson JE: MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors. J Biol Chem 2001, 276:16484-16490
59. Mikula M, Schreiber M, Husak Z, Kucerova L, Ruth J, Wieser R, Zatloukai K, Beug H, Wagner EF, Baccarini M: Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene. EMBO J 2001, 20:1952-1962
60. Jaskoll T, Choy HA, Melnick M: Glucocorticoids, TGF-beta, and embryonic mouse salivary gland morphogenesis. J Craniofac Genet Dev Biol 1994, 14:217-230
61. Torgerson TR, Colosia AD, Donahue JP, Lin Y-Z, Hawager J: Regulation of NF-κB, AP-1, NFAT, and STAT 1 nuclear import in T Lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-κB p50. J Immunol 1998, 161:6084-6092
62. Boothby M: Specificity of SN50 for NF-κB? Nature Immunol 2001, 2:471
63. Das J, Chen C-H, Yang L, Cohn L, Ray P, Ray A: A critical role for NF-κB in Gata3 expression and Th2 differentiation in allergic airway inflammation. Nature Immunol 2001, 2:45-50
64. Ray A: Response. Nature Immun 2001, 2:471-472
65. Bains W: The parts of life. Nature Biotech 2001, 19:401-402
66. Watts DJ, Strogatz SH: Collective dynamics of 'small-world' networks. Nature 1998, 393:440-442
67. Asthagiri AR, Lauffenberger DA: A computational study of feedback effects on signal dynamics in a mitogen-induced protein kinase (MAPK) pathway model. Biotechnol Prog 2001, 17:227-239
68. Theiler K: The House Mouse. New York: Springer-Verlag 1989
69. Specht D: Probabilistic neural networks for classification, mapping, or associative memory. Proc IEEE Int Conf Neural Networks 1988, 1:525-532
70. Specht D: Probabilistic neural networks. Neural Networks 1990, 3:109-118
71. Specht D, Shapiro P: Generalization accuracy of probabilistic neural networks compared with back-propagation networks. Proc Int Joint Conf Neural Networks 1991, 1:887-892
72. Chen C: Fuzzy logic and neural network handbook. New York: McGraw-Hill 1996
73. Sokal RR, Rohlf FJ: Biometry. New York: Freeman 1981
74. Abe K, Saito H: Neurotrophic effect of basic fibroblast growth factor is mediated by the p42/p44 mitogen-activated protein kinase cascade in cultured rat cortical neurons. Dev Brain Res 2000, 122:81-85
75. Callaerts P, Halder G, Gehring W: PAX-6 in development and evolution. Annu Rev Neurosci 1997, 20:483-532
76. Candela M, Barker SC, Ballon LR: Fibroblast growth factor increases TNF alpha-mediated prostaglandin E2 production and TNF alpha receptor expression in human fibroblasts. Mol Cell Biochem 1993, 120:43-50
77. Cano E, Mahadevan L: Parallel signal processing among mammalian MAPKs. Science 1995, 4:117-122
78. Coppola D, Ferber A, Miura M, Sell C, D'Ambrosio C, Rubin R, Baserga R: A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol Cell Biol 1994, 14:4588-4595
79. Davis RJ: Signal transduction by the JNK group of MAP kinases. Cell 2000, 103:239-252
80. De Benedetti F, Alonzi T, Moretta A, et al: Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I: a model for stunted growth in children with chronic inflammation. J Clin Inv 1997, 99:643-650
81. de Martin R, Schmid J, Hofer-Warbinek R: The NF-κB/Rel family of transcription factors in oncogenic transformation and apoptosis. Mutation Res 1999, 437:231-243
82. Glienke J, Fenten G, Seemann M, Sturz A, Thierauch K-H: Human SPRY2 inhibits FGF2 signalling by a secreted factor. Mech Dev 2000, 96:91-99
83. Harris V, Coticchia C, Kagan B, Ahmad S, Wellstein A, Riegel A: Induction of the angiogenic modulator fibroblast growth factor-binding protein by epidermal growth factor is mediated through both MEK/ERK and p38 signal transduction pathways. J Biol Chem 2000, 275:10802-10811
84. Hart K, Robertson S, Kanemitsu M, Meyer A, Tynan J, Donoghue D: Transformation and stat activation by derivatives of FGFR1, FGFR3, and FGFR4. Oncogene 2000, 19:3309-3320
85. Janknecht R, Hunter T: Nuclear fusion of signaling pathways. Science 1999, 284:443-444
86. Janson W, Brandner G, Siegel J: Butyrate modules DNA-damage-induced p53 response by induction of p53-independent differentiation and apoptosis. Oncogene 1997, 15:1395-1406
87. Kelliher M, Grimm S, Ishida Y, Kuo F, Stanger B, Leder P: The death domain kinase RIP mediates the TNF-induced NF-κB signal. Immunity 1998, 8:297-303
88. Klint P, Kanda S, Kloog Y, Claesson-Welsh L: Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation. Oncogene 1999, 18:3354-3364
89. Kyriakis J, Banerjee P, Nikolakaki E, et al: The stress-activated protein kinase subfamily of c-Jun kinases. Nature 1994, 369:156-160
90. Li F, Ambrosini G, Chu E, Plescia J, Tognin S, Marchisio PC, Altieri DC: Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 1998, 396:580-583
91. Massague J, Blain S, Lo R: TGF-β signaling in growth control, cancer, and heritable disorders. Cell 2000, 103:295-309
92. Minowada G, Jarvis L, Chi C, Neubuser A, Sun X, Hacohen N, Krasnow MA, Martin GR: Vertebrate sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 1999, 126:4465-4475
93. Prisco M, Hongo A, Giulia R, Sacchi A, Baserga R: The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal. Mol Cell Biol 19971084-1092
94. Qu Z, Huang X, Stenberg P, Le A-C, Planck S, Rosenbaum J: Synthesis of basic fibroblast growth factor by murine mast cells. Int Arch Allergy Immunol 1998, 115:47-54
95. Richardson N, Chamberlain C, McAvoy J: IGF-1 enhancement of FGF-induced lens fiber differentiation in rats of different ages. Inv Ophtal Vis Sci 1993, 34:3303-3312
96. Ring C, Cho K: Insights from model systems specificity in transforming growth factor-beta signaling pathways. Am J Hum Genet 1999, 64:691-697
97. Schlessinger J: Cell Signaling by receptor tyrosine kinases. Cell 2000, 103:211-225
98. Shikama N, Lee C-W, France S, Delavaine L, Lyon J, Krstic-Demonacos M, La Thangue NB: A novel cofactor for p300 that regulates the p53 response. Mol Cell 1999, 4:365-376
99. Sluss H, Barrett T, Derijard B, Davis R: Signal transduction by tumor necrosis factor mediated by JNK protein kinases. Mol Cell Biol 1994, 14:8376-8384
100. Stroschein S, Wang W, Zhou S, Zhou Q, Luo K: Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein. Science 1999, 286:771-774
101. Suzuki A, Ito T, Kawano H, et al: Survivin initiates procaspase 3/p21 complex formation as a result of interaction with Cdk4 to resist Fas-mediated cell death. Oncogene 2000, 19:1346-1353
102. Szebenyi G, Fallon J: Fibroblast growth factors as multifunctional signaling factors. Int Rev Cyt 1999, 185:45-106
103. Tan M, Wang Y, Guan K, Sun Y: PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway. Proc Natl Acad Sci (USA) 2000, 97:109-114
104. Tomoda K, Kubota Y, Kato J-Y: Degradation of the cyclin-dependent-kinase inhibitor p27kip1 is instigated by Jab 1. Nature 1999, 398:160-165
105. Ulloa L, Doody J, Massague J: Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-y/STAT pathway. Nature 1999, 397:710-713
106. Visser J, Themmen A: Downstream factors in transforming growth factor-beta family signaling. Mol Cell End 1998, 146:7-17
107. Warburton D, Schwarz M, Tefft D, Flores-Delgado G, Anderson K, Cardoso W: The molecular basis of lung morphogenesis. Mech Dev 2000, 92:55-81
108. Wu Y, Tewari M, Cui S, Rubin R: Activation of the insulin-like growth factor-I receptor inhibits tumor necrosis factor-induced cell death. J Cell Phys 1996, 168:499-509