Submandibular gland morphogenesis: Stage-specific expression of TGF- α/EGF, IGF, TGF-β, TNF, and IL-6 signal transduction in normal embryonic mice and the phenotypic effects of TGF-β2, TGF-β3, and EGF-R null mutations

Anatomical Record

Volumn 256, Issue 3, 1999, Pages 252-268

  Jaskoll, Tina ^a,b   Melnick, Michael ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Lab for Developmental Genetics   (United States)

Author keywords

Embryonic submandibular gland; IGF II; IL 6; TGF EGF; TGF ; TNF

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; INTERLEUKIN 6; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; TUMOR NECROSIS FACTOR;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL DIVISION; CELL INTERACTION; CELL PROLIFERATION; MORPHOGENESIS; MOUSE; NONHUMAN; ORGANOGENESIS; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBMANDIBULAR GLAND;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULIN-LIKE GROWTH FACTOR II; INTERLEUKIN-6; MALE; MICE; MORPHOGENESIS; MUTATION; PHENOTYPE; PREGNANCY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; SUBMANDIBULAR GLAND; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0032754678     PISSN: 0003276X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0185(19991101)256:3<252::AID-AR5>3.0.CO;2-6     Document Type: Article

References (46)

1. Ashkenazi A, Dixit VM. 1998. Death receptors: signaling and modulation. Science 281:1305-1308.
2. Baker J, Liu JP, Robertson EJ, Efstratiadis A. 1993. Role of insulin-like growth factors in embryonic and postnatal growth. Cell 75: 73-82.
3. Ball WD, Hand AR, Moreira JE. 1991. A neonatal secretory protein associated with secretion granule membranes in developing rat salivary glands. J Histochem Cytochem 39:1693-1706.
4. Barlow DP. 1995. Gametic imprinting in mammals. Science 270:1610-1613.
5. Coppola D, Ferber A, Miura M, Sell C, D'Ambrosio C, Rubin R, Baserga R. 1994. A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor. Mol Cell Biol 14:4588-4595.
6. Cutler LS. 1990. The role of extracellular matrix in the morphogenesis and differentiation of salivary glands. Adv Dent Res 4:27-33.
7. Cutler LS, Gremski W. 1991. Epithelial-mesenchymal interactions in the development of salivary glands. Crit Rev Oral Biol Med 2:1-12.
8. Darnay BG, Aggarwal BB. 1997. Early events in TNF signaling: a story of associations and dissociations. J Leukoc Biol 61:559-566.
9. Dennis PA, Rifkin DB. 1991. Cellular activation of latent transforming growth factor β requires binding to the cation-independent mannose-6-phosphate/insulin-like growth factor II receptor. Proc Natl Acad Sci USA 88:580-584.
10. Derynck R. 1992. The physiology of transforming growth factor-α. Adv Cancer Res 58:27-52.
11. Derynck R. 1994. TGF-β-receptor mediated signaling. Trends Biochem Sci 19:548-553.
12. Frankfurt OS, Robb JA, Sugarbaker EV, Villa L. 1996. Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis. Exp Cell Res 226:387-397.
13. Gleizes PE, Munger JS, Nunes I, Harpel TG, Mazzieri R, Noguera I, Rifkin DB. 1997. TGF-β latency: biological significance and mechanisms of activation. Stem Cell 15:190-197.
14. Gresik EW, Kashimata M, Kadoya Y, Mathews R, Minami N, Yamashina S. 1997. Expression of epidermal growth factor receptor in fetal mouse submandibular gland detected by a biotinyltyramide-based catalyzed signal amplification method. J Histochem Cytochem 45:1651-1657.
15. Haig D, Graham C. 1991. Genomic imprinting and the strange case of the insulin-like growth factor II receptor. Cell 64:1045-1046.
16. Hardman P, Spooner BS. 1992. Localization of extracellular matrix components in developing mouse salivary glands by confocal microscopy. Anat Rec 234:452-459.
17. Hardman P, Landels E, Woolf AS, Spooner BS. 1994. TGF-β1 inhibits growth and branching morphogenesis in embryonic mouse submandibular and sublingual glands in vitro. Dev Growth Differ 36:567-577.
18. Hu PP, Datto MB, Wang XF. 1998. Molecular mechanisms of transforming growth factor β signaling. Endocr Rev 19:349-363.
19. Jaskoll T, Boyer PD, Melnick M. 1994a. Tumor necrosis factor-α and embryonic mouse lung morphogenesis. Dev Dyn 201:137-150.
20. Jaskoll T, Choy HA, Melnick M. 1994b. Glucocorticoids, TGF-β, and embryonic mouse salivary gland morphogenesis. J Craniofac Genet Dev Biol 14:217-230.
21. Jaskoll T, Chen H, Denny PC, Denny PA, Melnick M. 1998. Mouse submandibular gland mucin: embryo-specific mRNA and protein species. Mech Dev 74:179-183.
22. Kaartinen V, Voncken JW, Shuler C, Warburton D, Bu D, Heisterkamp N, Groffen J. 1995. Abnormal lung development and cleft palate in mice lacking TGF-beta 3 indicates defects of epithelial-mesenchymal interaction. Nat Genet 11:415-421.
23. Kashimata M, Gresik EW. 1997. Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the α6-integrin subunit. Dev Dyn 208:149-161.
24. Katz J, Nagler R, Barak S, Livneh A, Baum B, Atkinson J, Shemer J. 1994. Cytokines modulate interleukin-6 production by human salivary gland cell line. Cell Immunol 159:211-219.
25. Kulkarni AB, Huh CG, Becker D, Geiser A, Lyght M, Flanders K, Roberts AB, Sporn MB, Ward JM, Karlsson S. 1993. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 90:770-774.
26. Kurokouchi K, Kambe F, Yasukawa K, Izumi R, Ishiguro N, Iwata H, Seo H. 1998. TNF-α increases expression of IL-6 and ICAM-1 genes through activation of NF-KB in osteoblast-like ROS 17/2.8 cells. J Bone Miner Res 13:1290-1299.
27. Letterio JJ, Geiser AG, Kulkarni AB, Roche NS, Sporn MB, Roberts AB. 1994. Maternal rescue of transforming growth factor-β1 null mice. Science 264:1936-1938.
28. Macauly SP, Tarnuzzer RW, Schultz GS, Chegini N, Oxford GE, Humphreys-Beher MG. 1997. Extracellular matrix gene expression during mouse submandibular gland development. Archs Oral Biol 42:443-454.
29. Mandelbrot BB. 1983. The fractal geometry of nature. San Francisco: WH Freeman.
30. Melnick M, Choy HA, Jaskoll T. 1996. Glucocorticoids, tumor necrosis factor-α, and epidermal growth factor regulation of pulmonary morphogenesis: a multivariate in vitro analysis of their related actions. Dev Dyn 205:365-378.
31. Melnick M, Chen H, Buckley S, Warburton D, Jaskoll T. 1998. Insulin-like growth factor II receptor, transforming growth factor-β, and Cdk4 expression and the developmental epigenetics of mouse palate morphogenesis and dysmorphogenesis. Dev Dyn 211:11-25.
32. Miettinen PJ, Berger JE, Meneses J, Phung Y, Pederson RA, Werb Z, Derynck R. 1995. Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 376:337-341.
33. Miettinen PJ, Warburton D, Bu D, Zhao JS, Berger JE, Minoo P, Koivisto T, Dobbs E, Doestchmann T. 1997. Impaired lung branching morphogenesis in the absence of functional EGF receptor. Dev Biol 186:224-236.
34. Moreira JE, Ball WD, Mirels L, Hand AR. 1991. Accumulation and localization of two adult acinar cell secretory proteins during development of the rat submandibular gland. Am J Anat 191:167-184.
35. Nakanishi Y, Morita T, Nogawa H. 1987. Cell proliferation is not required for the initiation of early cleft formation in mouse embryonic submandibular epithelium in vitro. Development 99:429-437.
36. Nogawa H, Takahashi Y. 1991. Substitution for mesenchyme by basement-membrane-like substratum and epidermal growth factor in inducing branching morphogenesis of mouse salivary epithelium. Development 112:855-861.
37. Orr-Urtreger A, Lonai P. 1992. Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo. Development 115:1045-1058.
38. Partenen A. 1990. Epidermal growth factor and transforming growth factor-α in the development of epithelio-mesenchymal organs of the mouse. Curr Topics Dev Biol 24:31-55.
39. Ritvos O, Tuuri T, Eramaa M. Sainio K, Hilden K, Saxen L, Gilbert SF. 1995. Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse. Mech Dev 50:229-245.
40. Sanford LP, Ormsby I, Gittenberger-deGroot AC, Sariola H, Friedman R, Boivin GP, Cardell EL, Doetschman T. 1997. TGF-β2 knockout mice have multiple developmental defects that are non-overlapping with other TGF-β knockout phenotypes. Development 124:2659-2670.
41. Shull MM, Ormsby I, Kier AB, Pawlowski S, Diebold RJ, Yin M, Allen R, Sidman C. 1992. Targeted disruption of the transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359:693-699.
42. Sonnenberg E, Meyer D, Weidner KM, Birchmeier C. 1993. Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development. J Cell Biol 123:223-235.
43. Spooner BS, Bassett KE, Spooner Jr. BS. 1989. Embryonic salivary gland epithelial branching activity is experimentally independent of epithelial expansion activity. Dev Biol 133:569-575.
44. Theiler K. 1989. The house mouse. New York: Springer-Verlag.
45. Wessells NK. 1977. Tissue interactions and development. Menlo Park, CA: Benjamin Cummins.
46. Zhao JS, Sine PJ, Bringas P, Gauldie J, Warburton D. 1998. Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-beta type II receptor stimulates embryonic lung branching in culture and potentiates EGF and PDGF-A. Mech Dev 72:89-100.