Neurotrophic effect of basic fibroblast growth factor is mediated by the p42/p44 mitogen-activated protein kinase cascade in cultured rat cortical neurons

Developmental Brain Research

Volumn 122, Issue 1, 2000, Pages 81-85

  Abe, Kazuho ^a   Saito, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Basic fibroblast growth factor; Culture; Mitogen activated protein kinase; Neuronal survival; Rat cortical neuron

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT BASIC FIBROBLAST GROWTH FACTOR;

ANIMAL CELL; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; EMBRYO; ENZYME ACTIVITY; IN VITRO STUDY; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; FIBROBLAST GROWTH FACTOR 2; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; RATS; RATS, WISTAR;

EID: 0034734125     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(00)00054-7     Document Type: Article

References (24)

1. 2+-dependent late phase. J. Neurochem. 67:1996;2074-2078.
2. Abe K., Saito H. The p44/42 mitogen-activated protein kinase cascade is involved in the induction and maintenance of astrocyte stellation mediated by protein kinase C. Neurosci. Res. 36:2000;251-257.
3. Abe K., Takayanagi M., Saito H. Effects of recombinant human basic fibroblast growth factor and its modified protein CS23 on survival of primary cultured neurons from various regions of fetal rat brain. Jpn. J. Pharmacol. 53:1990;221-227.
4. Abe K., Takayanagi M., Saito H. Basic fibroblast growth factor and epidermal growth factor promote survival of primary cultured cerebellar neurons from neonatal rats. Jpn. J. Pharmacol. 56:1990;113-116.
5. Anderson K.J., Dam D., Lee S., Cotman C.W. Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo. Nature. 332:1988;360-361.
6. Corbit K.C., Foster D.A., Rosner M.R. Protein kinase Cδ mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells. Mol. Cell. Biol. 19:1999;4209-4218.
7. Dudley D.T., Pang L., Decker S.J., Bridges A.J., Saltiel A.R. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA. 92:1995;7686-7689.
8. Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Van Dyk D.E., Pitts W., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., Trzaskos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase. J. Biol. Chem. 273:1998;18623-18632.
9. Gospodarowicz D., Cheng J., Lui G.-M., Baird A., Bohlen P. Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Proc. Natl. Acad. Sci. USA. 81:1984;6963-6967.
10. Gospodarowicz D., Neufeld G., Schweiger L. Fibroblast growth factor. Mol. Cell. Endocrinol. 46:1986;187-204.
11. Ikeda M., Kito H., Sumpio B.E. Phosphatidylinositol-3 kinase dependent MAP kinase activation via p21 ras in endothelial cells exposed to cyclic strain. Biochem. Biophys. Res. Commun. 257:1999;668-671.
12. Kolch W., Heidecker G., Kochs G., Hummel R., Vahidi H., Mischak H., Finkenzeller G., Marme D., Rapp U.R. Protein kinase Cα activates RAF-1 by direct phosphorylation. Nature. 364:1993;249-252.
13. Lewis T.S., Shapiro P.S., Ahn N.G. Signal transduction through MAP kinase cascades. Adv. Cancer Res. 74:1998;49-139.
14. Marquardt B., Frith D., Stabel S. Signalling from TPA to MAP kinase requires protein kinase C, raf and MEK: reconstitution of the signalling pathway in vitro. Oncogene. 9:1994;3213-3218.
15. Morrison R.S., Sharma A., De Vellis J., Bradshow R.A. Basic fibroblast growth factor supports the survival of cerebral cortical neurons in primary culture. Proc. Natl. Acad. Sci. USA. 83:1986;7537-7541.
16. Petmann B., Labourdette G., Weibel M., Sensenbrenner M. The brain fibroblast growth factor (FGF) is localized in neurons. Neurosci. Lett. 68:1986;175-180.
17. Seger R., Krebs E.G. The MAPK signaling cascade. FASEB J. 9:1995;726-735.
18. Smalley K.S., Feniuk W., Sellers L.A., Humphrey P.P. The pivotal role of phosphoinotide-3 kinase in the human somatostatin sst(4) receptor-mediated stimulation of p44/p42 mitogen-activated protein kinase and extracellular acidification. Biochem. Biophys. Res. Commun. 263:1999;239-243.
19. Sugden P.H., Clerk A. Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors. Cell. Signal. 9:1997;337-351.
20. Takeda H., Matozaki T., Takada T., Noguchi T., Yamao T., Tsuda M., Ochi F., Fukunaga K., Inagaki K., Kasuga M. PI 3-kinase γ and protein kinase C-ζ-mediate RAS-independent activation of MAP kinase by a Gi protein-coupled receptor. EMBO J. 18:1999;386-395.
21. Ueda Y., Hirai S., Osada S., Suzuki A., Mizuno K., Ohno S. Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent of Raf. J. Biol. Chem. 271:1996;23512-23519.
22. Walicke P., Cowan W.M., Ueno N., Baird A., Guilemin R. Fibroblast growth factor promotes survival of dissociated hippocampal neurons and enhances neurite extension. Proc. Natl. Acad. Sci. USA. 83:1986;3012-3016.
23. Walicke P.A., Baird A. Neurotrophic effects of basic and acidic fibroblast growth factors are not mediated through glial cells. Brain Res. 468:1988;71-79.
24. Walicke P.A., Feige J.J., Andrew B. Characterization of the neuronal receptor for basic fibroblast growth factor and comparison to receptors on mesenchymal cells. J. Biol. Chem. 264:1989;4120-4126.