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Volumn 9, Issue 8, 2003, Pages 949-957

A common speed limit for RNA-cleaving ribozymes and deoxyribozymes

Author keywords

Catalysis; Deoxyribozyme; Enzymatic mechanism; Ribozyme; RNA cleavage; RNA transesterification

Indexed keywords

DEOXYRIBOZYME; ORGANOPHOSPHATE; RIBONUCLEASE A; RIBOZYME;

EID: 0041305819     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1261/rna.5670703     Document Type: Article
Times cited : (109)

References (28)
  • 1
    • 0000917638 scopus 로고    scopus 로고
    • In vitro selection of catalytic polynucleotides
    • Breaker, R.R. 1997. In vitro selection of catalytic polynucleotides. Chem. Rev. 97: 371-390.
    • (1997) Chem. Rev. , vol.97 , pp. 371-390
    • Breaker, R.R.1
  • 2
    • 0018796264 scopus 로고
    • Diastereomers of 5′-O-adenosyl 3′-O-uridyl phosphorothioate: Chemical synthesis and enzymatic properties
    • Burgers, P.M.J. and Eckstein, F. 1979. Diastereomers of 5′-O-adenosyl 3′-O-uridyl phosphorothioate: Chemical synthesis and enzymatic properties. Biochemistry 18: 592-596.
    • (1979) Biochemistry , vol.18 , pp. 592-596
    • Burgers, P.M.J.1    Eckstein, F.2
  • 3
    • 0035367070 scopus 로고    scopus 로고
    • Structure and function of the small ribozymes
    • Butcher, S.E. 2001. Structure and function of the small ribozymes. Curr. Opin. Struct. Biol. 11: 315-320.
    • (2001) Curr. Opin. Struct. Biol. , vol.11 , pp. 315-320
    • Butcher, S.E.1
  • 5
    • 0030877619 scopus 로고    scopus 로고
    • Hammerhead ribozymes with a faster cleavage rate
    • Clouet-d'Orval, B. and Uhlenbeck, O.C. 1997. Hammerhead ribozymes with a faster cleavage rate. Biochemistry 36: 9087-9092.
    • (1997) Biochemistry , vol.36 , pp. 9087-9092
    • Clouet-d'Orval, B.1    Uhlenbeck, O.C.2
  • 6
    • 0025998488 scopus 로고
    • Role of divalent metal ions in the hammerhead RNA cleavage reaction
    • Dahm, S.C. and Uhlenbeck, O.C. 1991. Role of divalent metal ions in the hammerhead RNA cleavage reaction. Biochemistry 30: 9464-9469.
    • (1991) Biochemistry , vol.30 , pp. 9464-9469
    • Dahm, S.C.1    Uhlenbeck, O.C.2
  • 7
    • 0028275049 scopus 로고
    • Structural determinants of enzymatic processivity
    • DelCardayré, S.B. and Raines, R.T. 1994. Structural determinants of enzymatic processivity. Biochemistry 33: 6031-6037.
    • (1994) Biochemistry , vol.33 , pp. 6031-6037
    • DelCardayré, S.B.1    Raines, R.T.2
  • 9
    • 0034708334 scopus 로고    scopus 로고
    • Structure and function of the hairpin ribozyme
    • Fedor, M.J. 2000. Structure and function of the hairpin ribozyme. J. Mol. Biol. 297:269-291.
    • (2000) J. Mol. Biol. , vol.297 , pp. 269-291
    • Fedor, M.J.1
  • 10
    • 0035965132 scopus 로고    scopus 로고
    • The A730 loop is an important component of the active site of the VS ribozyme
    • Lafontaine, D.A., Wilson, T.J., Norman, D.G., and Lilley, D.M.J. 2001. The A730 loop is an important component of the active site of the VS ribozyme. J. Mol. Biol. 312: 663-674.
    • (2001) J. Mol. Biol. , vol.312 , pp. 663-674
    • Lafontaine, D.A.1    Wilson, T.J.2    Norman, D.G.3    Lilley, D.M.J.4
  • 11
    • 0038475923 scopus 로고    scopus 로고
    • Substrate specificity and reaction kinetics of an X-motif ribozyme
    • Lazarev, D., Puskarz, I., and Breaker, R.R. 2003. Substrate specificity and reaction kinetics of an X-motif ribozyme. RNA 9: 688-697.
    • (2003) RNA , vol.9 , pp. 688-697
    • Lazarev, D.1    Puskarz, I.2    Breaker, R.R.3
  • 12
    • 0033575087 scopus 로고    scopus 로고
    • Kinetics of RNA degradation by specific base catalysis of transesterification involving the 2′-hydroxyl group
    • Li, Y. and Breaker, R.R. 1999. Kinetics of RNA degradation by specific base catalysis of transesterification involving the 2′-hydroxyl group. J. Am. Chem. Soc. 121: 5364-5372.
    • (1999) J. Am. Chem. Soc. , vol.121 , pp. 5364-5372
    • Li, Y.1    Breaker, R.R.2
  • 13
    • 0033150677 scopus 로고    scopus 로고
    • Structure, folding and catalysis of the small nucleolytic ribozymes
    • Lilley, D.M.J. 1999. Structure, folding and catalysis of the small nucleolytic ribozymes. Curr. Opin. Struct. Biol. 9: 330-338.
    • (1999) Curr. Opin. Struct. Biol. , vol.9 , pp. 330-338
    • Lilley, D.M.J.1
  • 14
    • 0035833978 scopus 로고    scopus 로고
    • Mechanistic characterization of the HDV genomic ribozyme: Assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism
    • Nakano, S., Proctor, D.J., and Bevilacqua, P.C. 2001. Mechanistic characterization of the HDV genomic ribozyme: Assessing the catalytic and structural contributions of divalent metal ions within a multichannel reaction mechanism. Biochemistry 40: 12022-12038.
    • (2001) Biochemistry , vol.40 , pp. 12022-12038
    • Nakano, S.1    Proctor, D.J.2    Bevilacqua, P.C.3
  • 15
    • 0034637161 scopus 로고    scopus 로고
    • The structural basis of ribosome activity in peptide bond synthesis
    • Nissen, P., Hansen, J., Ban, N., Moore, P.B., and Steitz, T.A. 2000. The structural basis of ribosome activity in peptide bond synthesis. Science 289: 920-930.
    • (2000) Science , vol.289 , pp. 920-930
    • Nissen, P.1    Hansen, J.2    Ban, N.3    Moore, P.B.4    Steitz, T.A.5
  • 16
    • 0028918401 scopus 로고
    • A proficient enzyme
    • Radzicka, A. and Wolfenden, R. 1995. A proficient enzyme. Science 267: 90-93.
    • (1995) Science , vol.267 , pp. 90-93
    • Radzicka, A.1    Wolfenden, R.2
  • 17
    • 0032568656 scopus 로고    scopus 로고
    • An amino acid as a cofactor for a catalytic polynucleotide
    • Roth, A. and Breaker, R.R. 1998. An amino acid as a cofactor for a catalytic polynucleotide. Proc. Natl. Acad. Sci. 95: 6027-6031.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 6027-6031
    • Roth, A.1    Breaker, R.R.2
  • 18
    • 0030898510 scopus 로고    scopus 로고
    • A general purpose RNA-cleaving DNA enzyme
    • Santoro, S.W. and Joyce, G.F. 1997. A general purpose RNA-cleaving DNA enzyme. Proc. Natl. Acad. Sci. 94: 4262-4266.
    • (1997) Proc. Natl. Acad. Sci. , vol.94 , pp. 4262-4266
    • Santoro, S.W.1    Joyce, G.F.2
  • 19
    • 0032558463 scopus 로고    scopus 로고
    • Mechanism and utility of an RNA-cleaving DNA enzyme
    • - . 1998. Mechanism and utility of an RNA-cleaving DNA enzyme. Biochemistry 37: 13330-13342.
    • (1998) Biochemistry , vol.37 , pp. 13330-13342
  • 20
    • 0033555778 scopus 로고    scopus 로고
    • A re-investigation of the thio effect at the hammerhead cleavage site
    • Scott, E.C. and Uhlenbeck, O.C. 1999. A re-investigation of the thio effect at the hammerhead cleavage site. Nucleic Acids Res. 27: 479-484.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 479-484
    • Scott, E.C.1    Uhlenbeck, O.C.2
  • 21
    • 0032831634 scopus 로고    scopus 로고
    • Relationship between internucleotide linkage geometry and the stability of RNA
    • Soukup, G.A. and Breaker, R.R. 1999. Relationship between internucleotide linkage geometry and the stability of RNA. RNA 5: 1308-1325.
    • (1999) RNA , vol.5 , pp. 1308-1325
    • Soukup, G.A.1    Breaker, R.R.2
  • 22
    • 0027184481 scopus 로고
    • A general two-metal-ion mechanism for catalytic RNA
    • Steitz, T.A. and Steitz, J.A. 1993. A general two-metal-ion mechanism for catalytic RNA. Proc. Natl. Acad. Sci. 90: 6498-6502.
    • (1993) Proc. Natl. Acad. Sci. , vol.90 , pp. 6498-6502
    • Steitz, T.A.1    Steitz, J.A.2
  • 23
    • 0035339966 scopus 로고    scopus 로고
    • Survey and Summary: Recent advances in the elucidation of the mechanisms of action of ribozymes
    • Takagi, Y., Warashina, M., Stec, W.J., Yoshinari, K., and Taira, K. 2001. Survey and Summary: Recent advances in the elucidation of the mechanisms of action of ribozymes. Nucleic Acids Res. 29: 1815-1834.
    • (2001) Nucleic Acids Res. , vol.29 , pp. 1815-1834
    • Takagi, Y.1    Warashina, M.2    Stec, W.J.3    Yoshinari, K.4    Taira, K.5
  • 24
    • 0030810710 scopus 로고    scopus 로고
    • Examination of the catalytic fitness of the hammerhead ribozyme by in vitro selection
    • Tang, J. and Breaker, R.R. 1997a. Examination of the catalytic fitness of the hammerhead ribozyme by in vitro selection. RNA 3: 914-925.
    • (1997) RNA , vol.3 , pp. 914-925
    • Tang, J.1    Breaker, R.R.2
  • 25
    • 0031171217 scopus 로고    scopus 로고
    • Rational design of allosteric ribozymes
    • - . 1997b. Rational design of allosteric ribozymes. Chem. Biol. 4: 453-459.
    • (1997) Chem. Biol. , vol.4 , pp. 453-459
  • 26
    • 0034705119 scopus 로고    scopus 로고
    • Structural diversity of self-cleaving ribozymes
    • - . 2000. Structural diversity of self-cleaving ribozymes. Proc. Natl. Acad. Sci. 97: 5784-5789.
    • (2000) Proc. Natl. Acad. Sci. , vol.97 , pp. 5784-5789
  • 27
    • 0000806492 scopus 로고
    • Hydrolytic stability of helical RNA: A selective advantage for the natural 3′,5′-bond
    • Usher, D.A. and McHale, A.H. 1976. Hydrolytic stability of helical RNA: A selective advantage for the natural 3′,5′-bond. Proc. Natl. Acad. Sci. 73: 1149-1153.
    • (1976) Proc. Natl. Acad. Sci. , vol.73 , pp. 1149-1153
    • Usher, D.A.1    McHale, A.H.2
  • 28
    • 0033880440 scopus 로고    scopus 로고
    • Differences among mechanisms of ribozyme-catalyzed reactions
    • Warashina, M., Takagi, Y., Stec, W.J., and Taira, K. 2000. Differences among mechanisms of ribozyme-catalyzed reactions. Curr. Opin. Biotechnol. 11: 354-362.
    • (2000) Curr. Opin. Biotechnol. , vol.11 , pp. 354-362
    • Warashina, M.1    Takagi, Y.2    Stec, W.J.3    Taira, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.