The hairpin ribozyme: From crystal structure to function

Biochemical Society Transactions

Volumn 30, Issue 6, 2002, Pages 1105-1109

  Ferre D'Amare A R ^a   Rupert, P B ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Catalytic RNA; Induced fit; Ribonuclease; Transesterification

Indexed keywords

RIBOZYME;

CATALYSIS; CONFERENCE PAPER; CRYSTAL STRUCTURE; ENZYME INHIBITOR COMPLEX; HUMAN; INTRON; NONHUMAN; PRIORITY JOURNAL; RNA ANALYSIS; RNA STRUCTURE; STRUCTURE ANALYSIS;

CATALYTIC DOMAIN; MODELS, CHEMICAL; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RNA; RNA, CATALYTIC; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0036863323     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0301105     Document Type: Conference Paper

References (30)

1. Fedor, M. J. (2000) J. Mol. Biol. 297, 269-291
2. Butcher, S. E., Heckman, J. E. and Burke, J. M. (1995) J. Biol. Chem. 270, 29648-29651
3. Shin, C., Choi, J. N., Song, S. I., Song, J. T., Ahn, J. H., Lee, J. S. and Choi, Y. D. (1996) Nucleic Acids Res. 24, 2685-2689
4. Murchie, A. I. H., Thomson, J. B., Walter, F. and Lilley, D. M. J. (1998) Mol. Cell 1, 873-881
5. Walter, N. G., Burke, J. M. and Millar, D. P. (1999) Nat. Struct. Biol. 6, 544-549
6. Doudna, J. A. and Cech, T. R. (2002) Nature (London) 418, 222-228
7. Rupert, P. B. and Ferré-D'Amaré, A. R. (2001) Nature (London) 410, 780-786
8. Walter, F., Murchie, A. I. H., Thomson, J. B. and Lilley, D. M. J. (1998) Biochemistry 37, 14195-14203
9. Scott, W. G., Finch, J. T. and Klug, A. (1995) Cell 81, 991-1002
10. Ferré-D'Amaré, A. R. and Doudna, J. A. (1996) Nucleic Acids Res. 24, 977-978
11. Ferré-D'Amaré, A. R., Zhou, K. and Doudna, J. A. (1998) J. Mol. Biol. 279, 621-631
12. Oubridge, C., Ito, N., Evans, P. R., Teo, C.-H. and Nagai, K. (1994) Nature (London) 372, 432-438
13. Ferré-D'Amaré, A, R., Zhou, K. and Doudna, J. A. (1998) Nature (London) 395, 567-574
14. Ferré-D'Amaré, A. R. and Doudna, J. A. (2000) J. Mol. Biol. 295, 541-556
15. Ferré-D'Amaré, A. R. and Doudna, J. A. (2000) in Current Protocols in Nucleic Acid Chemistry (Beaucage, S. L., Bergstrom, D. E., Glick, G. D. and Jones, R. A., eds), pp. 7.6.1-7.6.10, John Wiley & Sons, New York
16. Hampel, K. J., Walter, N. G. and Burke, J. M. (1998) Biochemistry 37, 14672-14682
17. Cai, Z. and Tinoco, I. J. (1996) Biochemistry 35, 6026-6036
18. Butcher, S. E., Allain, F. H.-T. and Feigon, J. (1999) Nat. Struct. Biol. 6, 212-216
19. van Tol, H., Buzayan, J. M., Feldstein, P. A., Eckstein, F. and Bruening, G. (1990) Nucleic Acids. Res. 18, 1971-1975
20. Richards, F. M., Wyckoff, H. W., Carlson, W. D., Allewell, N. M., Lee, B. and Mitsui, Y. (1971) Cold Spring Harbor Symp. Quant. Biol. 36, 35-43
21. Saenger, W. (1984) Principles of Nucleic Acid Structure, Springer-Verlag, New York
22. Fedor, M. (2002) Curr. Opin. Struct. Biol. 12, 289-295
23. Cowan, J. A. (1993) J. Inorg. Biochem. 49, 171-175
24. Hampel, A. and Cowan, J. A. (1997) Chem. Biol. 4, 513-517
25. Nesbitt, S., Hegg, L. A. and Fedor, M. J. (1997) Chem. Biol. 4, 619-630
26. Young, K. J., Gill, F. and Grasby, J. A. (1997) Nucleic Acids Res. 25, 3760-3766
27. Perrotta, A. T., Shih, I. and Been, M. D. (1999) Science 286, 123-126
28. Nakano, S.-I., Chadalavada, D. M. and Bevilacqua, P. C. (2000) Science 287, 1493-1497
29. Pinard, R., Hampel, K. J., Heckman, J. E., Lambert, D., Chan, P. A., Major, F. and Burke, J. M. (2001) EMBO J. 20, 6434-6442
30. Ryder, S. P., Oyelere, A. K., Padilla, J. L., Klostermeier, D., Millar, D. P. and Strobel, S. A. (2001) RNA 7, 1454-1463