Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

Genes and Development

Volumn 18, Issue 12, 2004, Pages 1413-1422

  Aslanian, Aaron ^a   Iaquinta, Phillip J ^a   Verona, Raluca ^a,b   Lees, Jacqueline A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

E2F3; Oncogenic activation; p19Arf p53; Proliferation; Tumor surveillance

Indexed keywords

CYCLIN D; CYCLIN DEPENDENT KINASE 4; ISOPROTEIN; PROTEIN MDM2; PROTEIN P16; PROTEIN P19; PROTEIN P21; PROTEIN P53; REPRESSOR PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F3; TRANSCRIPTION FACTOR E2F3A; TRANSCRIPTION FACTOR E2F3B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARF GENE; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL PROLIFERATION; CELL TRANSFORMATION; EMBRYO; FIBROBLAST; GENE LOSS; GENE MUTATION; GENE REPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL CYCLE; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DOWN-REGULATION; E2F3 TRANSCRIPTION FACTOR; FIBROBLASTS; KINETICS; MICE; MICE, KNOCKOUT; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 2942547243     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.1196704     Document Type: Article

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