E2F3 loss has opposing effects on different pRB-deficient tumors, resulting in suppression of pituitary tumors but metastasis of medullary thyroid carcinomas

Molecular and Cellular Biology

Volumn 23, Issue 18, 2003, Pages 6542-6552

  Ziebold, Ulrike ^a,c   Lee, Eunice Y ^a   Bronson, Roderick T ^b   Lees, Jacqueline A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b TUFTS UNIVERSITY   (United States)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGENIC AGENT; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DEATH; DOSE RESPONSE; EMBRYO; GENE ACTIVATION; HYPOPHYSIS TUMOR; KNOCKOUT MOUSE; LIFESPAN; METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYROID MEDULLARY CARCINOMA; TUMOR SUPPRESSOR GENE;

ANIMALS; ANIMALS, NEWBORN; CARCINOMA, MEDULLARY; E2F3 TRANSCRIPTION FACTOR; FEMALE; FETAL VIABILITY; GENE DOSAGE; HETEROZYGOTE; LONGEVITY; MALE; MICE; MICE, MUTANT STRAINS; MUTATION; NEOPLASM METASTASIS; PHENOTYPE; PITUITARY NEOPLASMS; RETINOBLASTOMA PROTEIN; THYROID NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0042190650     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.18.6542-6552.2003     Document Type: Article

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