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Volumn 147, Issue 1, 2006, Pages 222-231

Posttranslational, reversible O-glycosylation is stimulated by high glucose and mediates plasminogen activator inhibitor-1 gene expression and Sp1 transcriptional activity in glomerular mesangial cells

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLGLUCOSAMINIDASE; CARBAMIC ACID DERIVATIVE; ENZYME INHIBITOR; GLUCOSE; MESSENGER RNA; N ACETYLGLUCOSAMINYLTRANSFERASE; O (2 ACETAMIDO 2 DEOXY DETXRO GLUCOPYRANOSYLIDENE)AMINO N PHENYLCARBAMIC ACID; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSCRIPTION FACTOR SP1; UNCLASSIFIED DRUG;

EID: 29344459211     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2005-0523     Document Type: Article
Times cited : (89)

References (50)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group 1993 The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 329:977-986
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 2
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M 2001 Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 3
    • 0037184495 scopus 로고    scopus 로고
    • Molecular understanding of hyperglycemia's adverse effects for diabetic complications
    • Sheetz MJ, King GL 2002 Molecular understanding of hyperglycemia's adverse effects for diabetic complications. JAMA 288:2579-2588
    • (2002) JAMA , vol.288 , pp. 2579-2588
    • Sheetz, M.J.1    King, G.L.2
  • 4
    • 3042613480 scopus 로고    scopus 로고
    • O-GlcNAc a sensor of cellular state: The role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress
    • Zachara NE, Hart GW 2004 O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. Biochim Biophys Acta 1673:13-28
    • (2004) Biochim Biophys Acta , vol.1673 , pp. 13-28
    • Zachara, N.E.1    Hart, G.W.2
  • 5
    • 0036181947 scopus 로고    scopus 로고
    • Hexosamines as mediators of nutrient sensing and regulation in diabetes
    • McClain DA 2002 Hexosamines as mediators of nutrient sensing and regulation in diabetes. J Diabetic Compl 16:72-80
    • (2002) J Diabetic Compl , vol.16 , pp. 72-80
    • McClain, D.A.1
  • 7
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • USA
    • Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M 2000 Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci USA 97:12222-12226
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 12222-12226
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3    Fantus, I.G.4    Goldberg, H.5    Ziyadeh, F.6    Wu, J.7    Brownlee, M.8
  • 8
    • 0035180299 scopus 로고    scopus 로고
    • Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site
    • Du XL, Edelstein D, Dimmeler S, Ju O, Sui C, Brownlee M 2001 Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the Akt site. J Clin Invest 108:1341-1348
    • (2001) J Clin Invest , vol.108 , pp. 1341-1348
    • Du, X.L.1    Edelstein, D.2    Dimmeler, S.3    Ju, O.4    Sui, C.5    Brownlee, M.6
  • 9
    • 0031975643 scopus 로고    scopus 로고
    • High glucose-induced transforming growth factor β1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells
    • Kolm-Litty V, Sauer U, Nerlich A, Lehmann R, Schleicher ED 1998 High glucose-induced transforming growth factor β1 production is mediated by the hexosamine pathway in porcine glomerular mesangial cells. J Clin Invest 101:160-169
    • (1998) J Clin Invest , vol.101 , pp. 160-169
    • Kolm-Litty, V.1    Sauer, U.2    Nerlich, A.3    Lehmann, R.4    Schleicher, E.D.5
  • 10
    • 0038632159 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase mediates hexosamine-induced TGFβ1 mRNA expression in human mesangial cells
    • Burt DJ, Gruden G, Thomas SM, Tutt P, Dell'Anna C, Viberti GC, Gnudi L 2003 P38 mitogen-activated protein kinase mediates hexosamine-induced TGFβ1 mRNA expression in human mesangial cells. Diabetologia 46:531-537
    • (2003) Diabetologia , vol.46 , pp. 531-537
    • Burt, D.J.1    Gruden, G.2    Thomas, S.M.3    Tutt, P.4    Dell'Anna, C.5    Viberti, G.C.6    Gnudi, L.7
  • 11
    • 17544379257 scopus 로고    scopus 로고
    • Glucose metabolism to glucosamine is necessary for glucose stimulation of transforming growth factor-α gene transcription
    • Sayeski PP, Kudlow JE 1996 Glucose metabolism to glucosamine is necessary for glucose stimulation of transforming growth factor-α gene transcription. J Biol Chem 271:15237-15243
    • (1996) J Biol Chem , vol.271 , pp. 15237-15243
    • Sayeski, P.P.1    Kudlow, J.E.2
  • 12
    • 0034663705 scopus 로고    scopus 로고
    • Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration
    • Han I, Oh ES, Kudlow JE 2000 Responsiveness of the state of O-linked N-acetylglucosamine modification of nuclear pore protein p62 to the extracellular glucose concentration. Biochem J 350:109-114
    • (2000) Biochem J , vol.350 , pp. 109-114
    • Han, I.1    Oh, E.S.2    Kudlow, J.E.3
  • 13
    • 0025855139 scopus 로고
    • Discovery of a metabolic pathway mediating glucose-induced densenitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance
    • Marshall S, Bacote V, Traxinger RR 1991 Discovery of a metabolic pathway mediating glucose-induced densenitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance. J Biol Chem 266:4706-4712
    • (1991) J Biol Chem , vol.266 , pp. 4706-4712
    • Marshall, S.1    Bacote, V.2    Traxinger, R.R.3
  • 14
    • 0032543680 scopus 로고    scopus 로고
    • A nutrient-sensing pathway regulates leptin gene expression in muscle and fat
    • Wang J, Liu R, Hawkins M, Barzilai N, Rossetti L 1998 A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature 393:684-688
    • (1998) Nature , vol.393 , pp. 684-688
    • Wang, J.1    Liu, R.2    Hawkins, M.3    Barzilai, N.4    Rossetti, L.5
  • 15
    • 0037117511 scopus 로고    scopus 로고
    • Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes
    • USA
    • Vosseller K, Wells L, Lane MD, Hart, GW 2002 Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes. Proc Natl Acad Sci USA 99:5313-5318
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 5313-5318
    • Vosseller, K.1    Wells, L.2    Lane, M.D.3    Hart, G.W.4
  • 19
    • 0034083716 scopus 로고    scopus 로고
    • Glucosamine activates the plasminogen activator-inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells
    • Goldberg HJ, Scholey J, Fantus IG 2000 Glucosamine activates the plasminogen activator-inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells. Diabetes 49:863-871
    • (2000) Diabetes , vol.49 , pp. 863-871
    • Goldberg, H.J.1    Scholey, J.2    Fantus, I.G.3
  • 20
    • 0033679319 scopus 로고    scopus 로고
    • Hexosamine regulation of glucose-mediated laminin synthesis in mesangial cells involves protein kinases A and C
    • Singh LP, CrookED2000 Hexosamine regulation of glucose-mediated laminin synthesis in mesangial cells involves protein kinases A and C. Am J Physiol 279:F646-F654
    • (2000) Am J Physiol , vol.279
    • Singh, L.P.1    Crook, E.D.2
  • 21
    • 0033680164 scopus 로고    scopus 로고
    • Overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) activates PAI promoter
    • James LR, Fantus IG, Goldberg H, Ly H, Scholey JW 2000 Overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) activates PAI promoter. Am J Physiol 279:F718-F727
    • (2000) Am J Physiol , vol.279
    • James, L.R.1    Fantus, I.G.2    Goldberg, H.3    Ly, H.4    Scholey, J.W.5
  • 22
    • 0037072740 scopus 로고    scopus 로고
    • The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-β I and -δ
    • Goldberg HJ, Whiteside CI, Fantus IG 2002 The hexosamine pathway regulates the plasminogen activator inhibitor-1 gene promoter and Sp1 transcriptional activation through protein kinase C-β I and -δ. J Biol Chem 277:33833-33841
    • (2002) J Biol Chem , vol.277 , pp. 33833-33841
    • Goldberg, H.J.1    Whiteside, C.I.2    Fantus, I.G.3
  • 23
    • 1942469517 scopus 로고    scopus 로고
    • Upstream stimulatory factor (USF) proteins induce human TGF-β1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: Upregulation of USF activity by the hexosamine biosynthetic pathway
    • Weigert C, Brodbeck K, Sawadogo M, Haring HU, Schleicher ED 2004 Upstream stimulatory factor (USF) proteins induce human TGF-β1 gene activation via the glucose-response element-1013/-1002 in mesangial cells: upregulation of USF activity by the hexosamine biosynthetic pathway. J Biol Chem 279:15908-15915
    • (2004) J Biol Chem , vol.279 , pp. 15908-15915
    • Weigert, C.1    Brodbeck, K.2    Sawadogo, M.3    Haring, H.U.4    Schleicher, E.D.5
  • 24
    • 0026723826 scopus 로고
    • Cell and matrix components of the glomerular mesangium in type I diabetes
    • Steffes MW, Bilous RW, Sutherland DE, Mauer SM 1992 Cell and matrix components of the glomerular mesangium in type I diabetes. Diabetes 41:679-684
    • (1992) Diabetes , vol.41 , pp. 679-684
    • Steffes, M.W.1    Bilous, R.W.2    Sutherland, D.E.3    Mauer, S.M.4
  • 25
    • 0346965700 scopus 로고    scopus 로고
    • O-GlcNAc modification is an endogenous inhibitor of the proteasome
    • Zhang F, Su K, Yang X, Bowe DB, Paterson AJ, Kudlow JE 2003 O-GlcNAc modification is an endogenous inhibitor of the proteasome. Cell 115:715-725
    • (2003) Cell , vol.115 , pp. 715-725
    • Zhang, F.1    Su, K.2    Yang, X.3    Bowe, D.B.4    Paterson, A.J.5    Kudlow, J.E.6
  • 26
    • 0030959555 scopus 로고    scopus 로고
    • Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats
    • Kreppel LK, Blomberg MA, Hart GW 1997 Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats. J Biol Chem 272:9308-9315
    • (1997) J Biol Chem , vol.272 , pp. 9308-9315
    • Kreppel, L.K.1    Blomberg, M.A.2    Hart, G.W.3
  • 27
    • 0030944105 scopus 로고    scopus 로고
    • O-linked GlcNac transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats
    • Lubas WA, Frank DW, Krause M, Hanover JA 1997 O-linked GlcNac transferase is a conserved nucleocytoplasmic protein containing tetratricopeptide repeats. J Biol Chem 272:9316-9324
    • (1997) J Biol Chem , vol.272 , pp. 9316-9324
    • Lubas, W.A.1    Frank, D.W.2    Krause, M.3    Hanover, J.A.4
  • 28
    • 0037127198 scopus 로고    scopus 로고
    • Dynamic O-glycosylation of nuclear and cytosolic proteins: Further characterization of the nucleocytoplasmic β-N-acetylglucosaminidase, O-GlcNAcase
    • Wells L, Gao Y, Mahoney JA, Vosseller K, Chen C, Rosen A, Hart GW 2002 Dynamic O-glycosylation of nuclear and cytosolic proteins: further characterization of the nucleocytoplasmic β-N-acetylglucosaminidase, O-GlcNAcase. J Biol Chem 277:1755-1761
    • (2002) J Biol Chem , vol.277 , pp. 1755-1761
    • Wells, L.1    Gao, Y.2    Mahoney, J.A.3    Vosseller, K.4    Chen, C.5    Rosen, A.6    Hart, G.W.7
  • 29
    • 0036231781 scopus 로고    scopus 로고
    • Flux through the hexosamine pathway is a determinant of nuclear factor κB-dependent promoter activation
    • James LR, Tang D, Ingram A, Ly H, Thai K, Cai L, Scholey JW 2002 Flux through the hexosamine pathway is a determinant of nuclear factor κB-dependent promoter activation. Diabetes 51:1146-1155
    • (2002) Diabetes , vol.51 , pp. 1146-1155
    • James, L.R.1    Tang, D.2    Ingram, A.3    Ly, H.4    Thai, K.5    Cai, L.6    Scholey, J.W.7
  • 30
    • 0035903192 scopus 로고    scopus 로고
    • Activation of the hexosamine pathway leads to deterioration of pancreatic β-cell function through the induction of oxidative stress
    • Kaneto H, Xu G, Song KH, Suzuma K, Bonner-Weir S, Sharma A, Weir GC 2001 Activation of the hexosamine pathway leads to deterioration of pancreatic β-cell function through the induction of oxidative stress. J Biol Chem 276:31099-31104
    • (2001) J Biol Chem , vol.276 , pp. 31099-31104
    • Kaneto, H.1    Xu, G.2    Song, K.H.3    Suzuma, K.4    Bonner-Weir, S.5    Sharma, A.6    Weir, G.C.7
  • 31
    • 0035863102 scopus 로고    scopus 로고
    • Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis
    • Wu G, Haynes TE, Li H, Yan, Meininger, CJ 2001 Glutamine metabolism to glucosamine is necessary for glutamine inhibition of endothelial nitric oxide synthesis. Biochem J 353:245-252
    • (2001) Biochem J , vol.353 , pp. 245-252
    • Wu, G.1    Haynes, T.E.2    Li, H.3    Yan4    Meininger, C.J.5
  • 33
    • 14844295081 scopus 로고    scopus 로고
    • Glucosamine-induced activation of glycogen biosynthesis in isolated adipocytes. Evidence for a rapid allosteric control mechanism within the hexosamine biosynthesis pathway
    • Marshall S, Nadeau O, Yamasaki K 2005 Glucosamine-induced activation of glycogen biosynthesis in isolated adipocytes. Evidence for a rapid allosteric control mechanism within the hexosamine biosynthesis pathway. J Biol Chem 280:11018-11024
    • (2005) J Biol Chem , vol.280 , pp. 11018-11024
    • Marshall, S.1    Nadeau, O.2    Yamasaki, K.3
  • 34
    • 20544441287 scopus 로고    scopus 로고
    • Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: Implication of gangliosides
    • Masson E, Wiernsperger N, Lagarde M, El Bawab S 2005 Glucosamine induces cell-cycle arrest and hypertrophy of mesangial cells: implication of gangliosides. Biochem J 388:537-544
    • (2005) Biochem J , vol.388 , pp. 537-544
    • Masson, E.1    Wiernsperger, N.2    Lagarde, M.3    El Bawab, S.4
  • 35
    • 0036068351 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 and the kidney
    • Eddy AA 2002 Plasminogen activator inhibitor-1 and the kidney. Am J Physiol 283:F209-F220
    • (2002) Am J Physiol , vol.283
    • Eddy, A.A.1
  • 36
    • 0036098955 scopus 로고    scopus 로고
    • Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy
    • Paueksakon P, Revelo MP, Ma LJ, Marcantoni C, Fogo AB 2002 Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy. Kidney Int 61:2142-2148
    • (2002) Kidney Int , vol.61 , pp. 2142-2148
    • Paueksakon, P.1    Revelo, M.P.2    Ma, L.J.3    Marcantoni, C.4    Fogo, A.B.5
  • 37
    • 0032533865 scopus 로고    scopus 로고
    • Regulation of mammalian pyruvate dehydrogenase α subunit gene expression by glucose in HepG2 cells
    • Tan J, Yang HS, Patel MS 1998 Regulation of mammalian pyruvate dehydrogenase α subunit gene expression by glucose in HepG2 cells. Biochem J 336:49-56
    • (1998) Biochem J , vol.336 , pp. 49-56
    • Tan, J.1    Yang, H.S.2    Patel, M.S.3
  • 38
    • 0037442984 scopus 로고    scopus 로고
    • Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase
    • Love DC, Kochran J, Cathey RL, Shin, SH, Hanover JA 2002 Mitochondrial and nucleocytoplasmic targeting of O-linked GlcNAc transferase. J Cell Sci 116:647-654
    • (2002) J Cell Sci , vol.116 , pp. 647-654
    • Love, D.C.1    Kochran, J.2    Cathey, R.L.3    Shin, S.H.4    Hanover, J.A.5
  • 39
    • 0034948273 scopus 로고    scopus 로고
    • Ectopic expression of the tetratricopeptide repeat domain of SPINDLY causes defects in gibberellin response
    • Tseng TS, Swain SM, Olszewski NE 2001 Ectopic expression of the tetratricopeptide repeat domain of SPINDLY causes defects in gibberellin response. Plant Physiol 126:1250-1258
    • (2001) Plant Physiol , vol.126 , pp. 1250-1258
    • Tseng, T.S.1    Swain, S.M.2    Olszewski, N.E.3
  • 42
    • 0346101768 scopus 로고    scopus 로고
    • Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells
    • Brasse-Lagnel C, Fairand A, Lavoinne A, Husson A 2003 Glutamine stimulates argininosuccinate synthetase gene expression through cytosolic O-glycosylation of Sp1 in Caco-2 cells. J Biol Chem 278:52504-52510
    • (2003) J Biol Chem , vol.278 , pp. 52504-52510
    • Brasse-Lagnel, C.1    Fairand, A.2    Lavoinne, A.3    Husson, A.4
  • 43
    • 0037341310 scopus 로고    scopus 로고
    • Palmitate-induced activation of the hexosamine pathway in human myotubes: Increased expression of glutamine:fructose-6-phosphate aminotransferase
    • Weigert C, Klopfer K, Kausch C, Brodbeck K, Stumvoll M, Haring HU, Schleicher ED 2003 Palmitate-induced activation of the hexosamine pathway in human myotubes: increased expression of glutamine:fructose-6-phosphate aminotransferase. Diabetes 52:650-656
    • (2003) Diabetes , vol.52 , pp. 650-656
    • Weigert, C.1    Klopfer, K.2    Kausch, C.3    Brodbeck, K.4    Stumvoll, M.5    Haring, H.U.6    Schleicher, E.D.7
  • 44
    • 0032488979 scopus 로고    scopus 로고
    • Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-β-N- acetylglucosaminidase inhibitor O-(2-Acetoamido-2-deoxy-D-glucopyranosylidene) amino-N-phenylcarbamate
    • Haltiwanger RS, Grove K, Philipsberg GA 1998 Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-β-N-acetylglucosaminidase inhibitor O-(2-Acetoamido-2- deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate. J Biol Chem 273:3611-3617
    • (1998) J Biol Chem , vol.273 , pp. 3611-3617
    • Haltiwanger, R.S.1    Grove, K.2    Philipsberg, G.A.3
  • 45
    • 0035811072 scopus 로고    scopus 로고
    • O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability
    • USA
    • Yang X, Su K, Roos MD, Chang Q, Paterson AJ, Kudlow JE 2001 O-linkage of N-acetylglucosamine to Sp1 activation domain inhibits its transcriptional capability. Proc Natl Acad Sci USA 98:6611-6616
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 6611-6616
    • Yang, X.1    Su, K.2    Roos, M.D.3    Chang, Q.4    Paterson, A.J.5    Kudlow, J.E.6
  • 46
    • 0037067659 scopus 로고    scopus 로고
    • Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: Coupling protein O-GlcNAcylation to transcriptional repression
    • Yang X, Zhang F, Kudlow JE 2002 Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. Cell 110:69-80
    • (2002) Cell , vol.110 , pp. 69-80
    • Yang, X.1    Zhang, F.2    Kudlow, J.E.3
  • 47
    • 0942279632 scopus 로고    scopus 로고
    • Hexosamines and TGF-β1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells
    • Singh LP, Green K, Alexander M, Bassly S, Crook ED 2004 Hexosamines and TGF-β1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells. Am J Physiol 286:F409-F416
    • (2004) Am J Physiol , vol.286
    • Singh, L.P.1    Green, K.2    Alexander, M.3    Bassly, S.4    Crook, E.D.5
  • 48
    • 0942287200 scopus 로고    scopus 로고
    • The coactivator of transcription CREB binding protein interacts preferentially with the glycosylated form of Stat5
    • Gewinner C, Hart G, Zachara N, Cole R, Beisenherz-Huss C, Groner B 2003 The coactivator of transcription CREB binding protein interacts preferentially with the glycosylated form of Stat5. J Biol Chem 279:3563-3572
    • (2003) J Biol Chem , vol.279 , pp. 3563-3572
    • Gewinner, C.1    Hart, G.2    Zachara, N.3    Cole, R.4    Beisenherz-Huss, C.5    Groner, B.6
  • 49
    • 0141785482 scopus 로고    scopus 로고
    • High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells
    • Hsieh TJ, Fustier P, Zhang SL, Filep JG, Tang SS, Ingelfinger JR, Fantus IG, Hamet P, Chan JS 2003 High glucose stimulates angiotensinogen gene expression and cell hypertrophy via activation of the hexosamine biosynthesis pathway in rat kidney proximal tubular cells. Endocrinology 144:4338-4349
    • (2003) Endocrinology , vol.144 , pp. 4338-4349
    • Hsieh, T.J.1    Fustier, P.2    Zhang, S.L.3    Filep, J.G.4    Tang, S.S.5    Ingelfinger, J.R.6    Fantus, I.G.7    Hamet, P.8    Chan, J.S.9
  • 50
    • 17644420058 scopus 로고    scopus 로고
    • Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils
    • Kneass ZT, Marchase RB 2005 Protein O-GlcNAc modulates motility-associated signaling intermediates in neutrophils. J Biol Chem 280:14579-14585
    • (2005) J Biol Chem , vol.280 , pp. 14579-14585
    • Kneass, Z.T.1    Marchase, R.B.2


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