Hexosamines and TGF-β1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells

American Journal of Physiology - Renal Physiology

Volumn 286, Issue 2 55-2, 2004, Pages

  Singh, Lalit P ^a   Green, Kenneith ^a   Alexander, Michelle ^a   Bassly, Shira ^a   Crook, Errol D ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARPER UNIVERSITY HOSPITAL   (United States)

Author keywords

Cell signaling; Diabetic nephropathy; Extracellular matrix protein; Hexosamine pathway; Transforming growth factor

Indexed keywords

CELL PROTEIN; FIBRONECTIN; GLUCOSE; HEXOSAMINE; LAMININ; LUCIFERASE; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA1; ADENOSINE TRIPHOSPHATE; ANTIBODY; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DRUG DERIVATIVE; ENZYME INHIBITOR; GLUCOSAMINE; GLUCOSAMINE 6 PHOSPHATE; GLUCOSAMINE 6-PHOSPHATE; GLUCOSE 6 PHOSPHATE; PROTEIN KINASE C; TGFB1 PROTEIN, RAT; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ARTICLE; DIABETIC NEPHROPATHY; EXTRACELLULAR MATRIX; GLUCOSE METABOLISM; MESANGIUM CELL; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; MESANGIUM; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIBODIES; CELL LINE, TRANSFORMED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; EXTRACELLULAR MATRIX PROTEINS; FIBRONECTINS; GLOMERULAR MESANGIUM; GLUCOSAMINE; GLUCOSE; GLUCOSE-6-PHOSPHATE; HEXOSAMINES; LAMININ; PHOSPHORYLATION; PROTEIN KINASE C; RATS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 0942279632     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00007.2003     Document Type: Article

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