Cre/loxP-mediated CTLA4IgG gene transfer induces clinically relevant immunosuppression via on-off gene recombination in vivo

Cardiovascular Research

Volumn 69, Issue 1, 2006, Pages 289-297

  Izawa, Atsushi ^a   Sano, Kenji ^b   Takehara, Megumi ^c   Inobe, Manabu ^c   Suzuki, Jun Ichi ^d   Imamura, Hiroshi ^b   Takahashi, Masafumi ^a   Ikeda, Uichi ^a   Isobe, Mitsuaki ^d   Uede, Toshimitsu ^c  

^a SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HOKKAIDO UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Allograft rejection; Cre loxP recombination; CTLA4IgG; Gene therapy; Transplantation

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE LOCATION; GENE TRANSFER; GENETIC RECOMBINATION; HEART GRAFT; HEART TRANSPLANTATION; IMMUNOSUPPRESSIVE TREATMENT; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

ADENOVIRIDAE; ANIMALS; B-LYMPHOCYTES; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC VECTORS; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; IMMUNOCONJUGATES; IMMUNOSUPPRESSION; INTEGRASES; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; RECOMBINATION, GENETIC; SKIN TRANSPLANTATION; TRANSDUCTION, GENETIC; TRANSPLANTATION, HOMOLOGOUS;

EID: 29144459151     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2005.07.021     Document Type: Article

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