Blockade of T cell costimulatory signals using adenovirus vectors prevents both the induction and the progression of experimental autoimmune myocarditis

Journal of Molecular and Cellular Cardiology

Volumn 34, Issue 3, 2002, Pages 279-295

  Matsui, Yutaka ^a,b   Inobe, Manabu ^a   Okamoto, Hiroshi ^b   Chiba, Satoru ^a,b   Shimizu, Toshihiro ^b   Kitabatake, Akira ^b   Uede, Toshimitsu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenovirus vector; CD40Ig; CTLA4Ig; Experimental autoimmune myocarditis; Gene transfer; Immune response; T cell anergy; T cell mediated autoimmune disease

Indexed keywords

ADENOVIRUS VECTOR; CD28 ANTIGEN; CD40 LIGAND; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; HYBRID PROTEIN; T LYMPHOCYTE RECEPTOR; ABATACEPT; ANTIBODY CONJUGATE; CD40 ANTIGEN; CYTOKINE; CYTOTOXIC T-LYMPHOCYTE ANTIGEN 4; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE COURSE; GENE TRANSFER; HEART WEIGHT; HUMORAL IMMUNITY; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MALE; MICROSCOPY; MOLECULAR INTERACTION; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; RAT; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ADENOVIRUS; ANIMAL; BODY WEIGHT; CYTOLOGY; GENE THERAPY; GENE VECTOR; GENETICS; HEART MUSCLE; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LEWIS RAT; LYMPHOCYTE ACTIVATION; METABOLISM; METHODOLOGY; PATHOLOGY;

ADENOVIRIDAE;

ADENOVIRIDAE; ANIMALS; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD40; ANTIGENS, DIFFERENTIATION; AUTOIMMUNE DISEASES; BODY WEIGHT; CYTOKINES; GENE THERAPY; GENETIC VECTORS; IMMUNOCONJUGATES; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE ACTIVATION; MALE; MYOCARDITIS; MYOCARDIUM; RATS; RATS, INBRED LEW; RNA, MESSENGER; T-LYMPHOCYTES;

EID: 0036513699     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1511     Document Type: Article

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