Spatio-temporally controlled site-specific somatic mutagenesis in the mouse

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 26, 1997, Pages 14559-14563

  Brocard, Jacques ^a   Warot, Xavier ^a   Wendling, Olivia ^a   Messaddeq, Nadia ^a   Vonesch, Jean Luc ^a   Chambon, Pierre ^a   Metzger, Daniel ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Cre recombinase; Epidermis; Tamoxifen inducible gene targeting

Indexed keywords

ESTROGEN RECEPTOR; RECOMBINASE; TAMOXIFEN;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; DNA CLEAVAGE; EPIDERMIS; GENE TARGETING; GENETIC RECOMBINATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC MUTATION; TRANSGENIC MOUSE;

ANIMALS; EPIDERMIS; GENE TARGETING; HUMANS; INTEGRASES; MICE; MICE, TRANSGENIC; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; TAMOXIFEN; VIRAL PROTEINS;

EID: 0031473544     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.26.14559     Document Type: Article

References (16)

1. Capecchi, M. R. (1989) Trends Genet. 5, 70-76.
2. Jaenisch, R. (1988) Science 240, 1468-1474.
3. Rajewsky, K., Gu, H., Kühn, R., Betz, U. A. K., Müller, W., Roes, J. & Schwenk, F. (1996) J. Clin. Invest. 98, 600-603.
4. Olson, E. N., Arnold, H. H., Rigby, P. W. J. & Wold, B. J. (1996) Cell 85, 1-4.
5. Sauer, B. & Henderson, N. (1989) Nucleic Adds Res. 17, 147-161.
6. Gu, H., Marth, J., Orban, P. C. & Rajewsky, K. (1994) Science 265, 103-106.
7. Tsien, J. Z., Chen, D. F., Gerber, D., Tom, C., Mercer, E. H., Anderson, D. J., Mayford, M., Kandel, E. R. & Tonegawa, S. (1996) Cell 87, 1317-1326.
8. Barlow, C., Schroeder, M., Lekstrom-Himes, J., Kylefjord, H., Deng, C. X., Wynshaw-Boris, A., Spiegelman, B. M. & Xanthopoulos, K. G. (1997) Nucleic Acids Res. 25, 2543-2545.
9. Kühn, R., Schwenk, F., Aguet, M. & Rajewsky, K. (1995) Science 269, 1427-1429.
10. Akagi, K., Sandig, V., Vooijs, M., Van der Valk, M., Giovannini, M., Strauss, M. & Berns, A. (1997) Nucleic Acids Res. 25, 1766-1773.
11. Metzger, D., Clifford, J., Chiba, H. & Chambon, P. (1995) Proc. Natl. Acad. Sci. USA 92, 6991-6995.
12. Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D. & Chambon, P. (1996) Proc. Natl. Acad. Sci. USA 93, 10887-10890.
13. Schmidt, E. V., Christoph, G., Zeller, R. & Leder, P. (1990) Mol. Cell. Biol. 10, 4406-4411.
14. Araki, K., Araki, M., Miyazaki, J. & Vassali, P. (1995) Proc. Natl. Acad. Sci. USA 92, 160-164.
15. Takahashi, K. & Coulombe, P. A. (1996) Proc. Natl. Acad. Sci. USA 93, 14776-14781.
16. Fuchs, E. (1990) J. Cell Biol. 111, 2807-2814.