Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: Absolute requirement for removal of caspase-6 prodomain

Cell Death and Differentiation

Volumn 9, Issue 10, 2002, Pages 1046-1056

  Cowling, V ^a   Downward, J ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

Apoptosis; Caspase; Cytochrome c

Indexed keywords

CASPASE 6; CASPASE 8; CELL EXTRACT; CYTOCHROME C; ENZYME PRECURSOR; PROTEIN BID; PROTEINASE;

APOPTOSIS; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME METABOLISM; ENZYME PURIFICATION; ENZYME REGULATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN SECRETION; SOLUBILITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASPASE 6; CASPASE 8; CASPASE 9; CASPASES; COS CELLS; CYTOCHROME C GROUP; CYTOSOL; ENDOPEPTIDASES; EUKARYOTIC CELLS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; JURKAT CELLS; MACROMOLECULAR SUBSTANCES; MITOCHONDRIA; MUTATION; PROTEIN STRUCTURE, TERTIARY;

EID: 0036790423     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401065     Document Type: Article

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