Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis

Clinical and Experimental Metastasis

Volumn 22, Issue 6, 2005, Pages 461-473

  Yasutome, Michiya ^a   Gunn, Jason ^a   Korc, Murray ^a,b  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Pancreatic cancer; Smad4; TGF

Indexed keywords

PROTEIN P21; PROTEIN P27; RETINOBLASTOMA PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CARCINOGENICITY; CELL FUNCTION; CELL LINE; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PANCREAS CANCER; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; TUMOR GROWTH; UPREGULATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CARCINOMA, PANCREATIC DUCTAL; CELL NUCLEUS; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; HUMANS; MICE; MICE, NUDE; NEOVASCULARIZATION, PATHOLOGIC; PANCREATIC NEOPLASMS; PHOSPHORYLATION; RETINOBLASTOMA PROTEIN; RNA, SMALL INTERFERING; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 28644443682     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-2891-x     Document Type: Article

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