메뉴 건너뛰기




Volumn 7, Issue 9, 1996, Pages 1343-1357

Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; CYCLINE; LYSINE; UBIQUITIN;

EID: 0029787091     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.7.9.1343     Document Type: Article
Times cited : (251)

References (52)
  • 1
    • 0028240049 scopus 로고
    • Closing the cell-cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle
    • Amon, A., Irniger, S., and Nasmyth, K. (1994). Closing the cell-cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell 77, 1037-1050.
    • (1994) Cell , vol.77 , pp. 1037-1050
    • Amon, A.1    Irniger, S.2    Nasmyth, K.3
  • 2
    • 0029863734 scopus 로고    scopus 로고
    • E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins
    • Aristarkhov, A., Eytan, E., Moghe, A., Admon, A., Hershko, A., and Ruderman, J.V. (1996). E2-C, a cyclin-selective ubiquitin carrier protein required for the destruction of mitotic cyclins. Proc. Natl. Acad. Sci. USA 93, 4294-4299.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 4294-4299
    • Aristarkhov, A.1    Eytan, E.2    Moghe, A.3    Admon, A.4    Hershko, A.5    Ruderman, J.V.6
  • 3
    • 0024562943 scopus 로고
    • The degradation signal in a short-lived protein
    • Bachmair, A., and Varshavsky, A. (1989). The degradation signal in a short-lived protein. Cell 56, 1019-1032.
    • (1989) Cell , vol.56 , pp. 1019-1032
    • Bachmair, A.1    Varshavsky, A.2
  • 4
    • 0027451961 scopus 로고
    • Utility of polyhistidine-tagged ubiquitin in the purification of ubiquitin-protein conjugates and as an affinity ligand for the purification of ubiquitin-specific hydrolases
    • Beers, E.P., and Callis, J. (1993). Utility of polyhistidine-tagged ubiquitin in the purification of ubiquitin-protein conjugates and as an affinity ligand for the purification of ubiquitin-specific hydrolases. J. Biol. Chem. 268, 21645-21649.
    • (1993) J. Biol. Chem. , vol.268 , pp. 21645-21649
    • Beers, E.P.1    Callis, J.2
  • 5
    • 0024514688 scopus 로고
    • A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein
    • Chau, V., Tobias, J.W., Bachmair, A., Marriott, D., Ecker, D.J., Gonda, D.K., and Varshavsky, A. (1989). A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein. Science 243, 1576-1583.
    • (1989) Science , vol.243 , pp. 1576-1583
    • Chau, V.1    Tobias, J.W.2    Bachmair, A.3    Marriott, D.4    Ecker, D.J.5    Gonda, D.K.6    Varshavsky, A.7
  • 6
    • 0028828193 scopus 로고
    • The self-destructive personality of a cell cycle in transition
    • Deshaies, R.J. (1995). The self-destructive personality of a cell cycle in transition. Curr. Opin. Cell Biol. 7, 781-789.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 781-789
    • Deshaies, R.J.1
  • 7
    • 0020961333 scopus 로고
    • Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division
    • Evans, T., Rosenthal, E.T., Youngblom, J., Distel, D., and Hunt, T. (1983). Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33, 389-396.
    • (1983) Cell , vol.33 , pp. 389-396
    • Evans, T.1    Rosenthal, E.T.2    Youngblom, J.3    Distel, D.4    Hunt, T.5
  • 8
    • 0028362030 scopus 로고
    • The yeast plasma membrane uracil permease is stabilized against stress-induced degradation by a point mutation in a cyclin-like "destruction box."
    • Galan, J.M., Volland, C., Urban-Grimal, D., and Haguenauer-Tsapis, R. (1994). The yeast plasma membrane uracil permease is stabilized against stress-induced degradation by a point mutation in a cyclin-like "destruction box." Biochem. Biophys. Res. Commun. 201, 769-775.
    • (1994) Biochem. Biophys. Res. Commun. , vol.201 , pp. 769-775
    • Galan, J.M.1    Volland, C.2    Urban-Grimal, D.3    Haguenauer-Tsapis, R.4
  • 9
    • 0026545073 scopus 로고
    • Cyclin B2 undergoes cell cycledependent nuclear translocation and, when expressed as a indestructible mutant, causes mitotic arrest in HeLa cells
    • Gallant, P., and Nigg, E.A. (1992). Cyclin B2 undergoes cell cycledependent nuclear translocation and, when expressed as a indestructible mutant, causes mitotic arrest in HeLa cells. J. Cell Biol. 117, 213-224.
    • (1992) J. Cell Biol. , vol.117 , pp. 213-224
    • Gallant, P.1    Nigg, E.A.2
  • 10
    • 0028123264 scopus 로고
    • Identification of a novel vertebrate cyclin: Cyclin B3 shares properties with both A- and B-type cyclins
    • Gallant, P., and Nigg, E.A. (1994). Identification of a novel vertebrate cyclin: cyclin B3 shares properties with both A- and B-type cyclins. EMBO J. 13, 595-605.
    • (1994) EMBO J. , vol.13 , pp. 595-605
    • Gallant, P.1    Nigg, E.A.2
  • 11
    • 0025777453 scopus 로고
    • A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis
    • Ghiara, J.B., Richardson, H.E., Sugimoto, K., Henze, M., Lew, D.J., Wittenberg, C., and Reed, S.I. (1991). A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65, 163-174.
    • (1991) Cell , vol.65 , pp. 163-174
    • Ghiara, J.B.1    Richardson, H.E.2    Sugimoto, K.3    Henze, M.4    Lew, D.J.5    Wittenberg, C.6    Reed, S.I.7
  • 12
    • 0029365999 scopus 로고
    • The only way out of mitosis
    • Glotzer, M. (1995). The only way out of mitosis. Curr. Biol. 5, 970-972.
    • (1995) Curr. Biol. , vol.5 , pp. 970-972
    • Glotzer, M.1
  • 13
    • 0026089183 scopus 로고
    • Cyclin is degraded by the ubiquitin pathway
    • Glotzer, M., Murray, A.W., and Kirschner, M.W. (1991). Cyclin is degraded by the ubiquitin pathway. Nature 349, 132-138.
    • (1991) Nature , vol.349 , pp. 132-138
    • Glotzer, M.1    Murray, A.W.2    Kirschner, M.W.3
  • 14
    • 0026055322 scopus 로고
    • Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts
    • Hershko, A., Ganoth, D., Pehrson, D., Palazzo, R., and Cohen, L.H. (1991). Methylated ubiquitin inhibits cyclin degradation in clam embryo extracts. J. Biol. Chem. 266, 16376-16379.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16376-16379
    • Hershko, A.1    Ganoth, D.2    Pehrson, D.3    Palazzo, R.4    Cohen, L.H.5
  • 15
    • 0021813071 scopus 로고
    • Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates
    • Hershko, A., and Heller, H. (1985). Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates. Biochem. Biophys. Res. Commun. 128, 1079-1086.
    • (1985) Biochem. Biophys. Res. Commun. , vol.128 , pp. 1079-1086
    • Hershko, A.1    Heller, H.2
  • 16
    • 0025853324 scopus 로고
    • The short-lived MAT α-2 transcriptional regulator is ubiquitinated in vivo
    • Hochstrasser, M., Ellison, M.J., Chau, V., and Varshavsky, A. (1991). The short-lived MAT α-2 transcriptional regulator is ubiquitinated in vivo. Proc. Natl. Acad. Sci. USA 88, 4606-4610.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4606-4610
    • Hochstrasser, M.1    Ellison, M.J.2    Chau, V.3    Varshavsky, A.4
  • 17
    • 0027319328 scopus 로고
    • Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor
    • Holloway, S.L., Glotzer, M., King, R.W., and Murray, A.W. (1993). Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor. Cell 73, 1393-1402.
    • (1993) Cell , vol.73 , pp. 1393-1402
    • Holloway, S.L.1    Glotzer, M.2    King, R.W.3    Murray, A.W.4
  • 18
    • 0026571114 scopus 로고
    • The requirements for protein synthesis and degradation and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo
    • Hunt, T., Luca, F.C., and Ruderman, J.V. (1992). The requirements for protein synthesis and degradation and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo. J. Cell Biol. 116, 707-724.
    • (1992) J. Cell Biol. , vol.116 , pp. 707-724
    • Hunt, T.1    Luca, F.C.2    Ruderman, J.V.3
  • 19
    • 0029033504 scopus 로고
    • Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast
    • Irniger, S., Piatti, S., Michaelis, C., and Nasmyth, K. (1995). Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast. Cell 81, 269-278.
    • (1995) Cell , vol.81 , pp. 269-278
    • Irniger, S.1    Piatti, S.2    Michaelis, C.3    Nasmyth, K.4
  • 20
    • 0025800585 scopus 로고
    • Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell-cycle transitions
    • Izumi, T., and Maller, J.L. (1991). Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell-cycle transitions. Mol. Cell. Biol. 11, 3860-3867.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 3860-3867
    • Izumi, T.1    Maller, J.L.2
  • 21
    • 0029131894 scopus 로고
    • The cellular content of Cdc25p, the ras exchange factor in Saccharomyces cerevisiae, is regulated by destabilization through a cyclin destruction box
    • Kaplon, T., and Jacquet, M. (1995). The cellular content of Cdc25p, the ras exchange factor in Saccharomyces cerevisiae, is regulated by destabilization through a cyclin destruction box. J. Biol. Chem. 270, 20742-20747.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20742-20747
    • Kaplon, T.1    Jacquet, M.2
  • 23
    • 0029004815 scopus 로고
    • A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
    • King, R.W., Peters, J.-M., Tugendreich, S., Rolfe, M., Hieter, P., and Kirschner, M.W. (1995). A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
    • (1995) Cell , vol.81 , pp. 279-288
    • King, R.W.1    Peters, J.-M.2    Tugendreich, S.3    Rolfe, M.4    Hieter, P.5    Kirschner, M.W.6
  • 24
    • 0029937513 scopus 로고    scopus 로고
    • The "destruction box" of cyclin a allows B-type cyclins to be ubiquitinated, but not efficiently destroyed
    • Klotzbücher, A., Stewart, E., Harrison, D., and Hunt, T. (1996). The "destruction box" of cyclin A allows B-type cyclins to be ubiquitinated, but not efficiently destroyed. EMBO J. 15, 3053-3064.
    • (1996) EMBO J. , vol.15 , pp. 3053-3064
    • Klotzbücher, A.1    Stewart, E.2    Harrison, D.3    Hunt, T.4
  • 26
    • 0029145653 scopus 로고
    • Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation
    • Li, J.K., Meyer, A.N., and Donoghue, D.J. (1995). Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation. Mol. Biol. Cell 9, 1111-1124.
    • (1995) Mol. Biol. Cell , vol.9 , pp. 1111-1124
    • Li, J.K.1    Meyer, A.N.2    Donoghue, D.J.3
  • 27
    • 0026691930 scopus 로고
    • Cyclin A-cys41 does not undergo cell cycledependent degradation in Xenopus extracts
    • Lorca, T., Devault, A., Colas, P., Van, L.A., Fesquet, D., Lazaro, J.B., and Doree, M. (1992). Cyclin A-cys41 does not undergo cell cycledependent degradation in Xenopus extracts. FEBS Lett. 306, 90-93.
    • (1992) FEBS Lett. , vol.306 , pp. 90-93
    • Lorca, T.1    Devault, A.2    Colas, P.3    Van, L.A.4    Fesquet, D.5    Lazaro, J.B.6    Doree, M.7
  • 28
    • 0025930898 scopus 로고
    • Both cyclin AΔ60 and BΔ97 are stable and arrest cells in M phase, but only cyclin BΔ97 turns on cyclin destruction
    • Luca, F.C., Shibuya, E.K., Dohrmann, C.E., and Ruderman, J.V. (1991). Both cyclin AΔ60 and BΔ97 are stable and arrest cells in M phase, but only cyclin BΔ97 turns on cyclin destruction. EMBO J. 20, 4311-4320.
    • (1991) EMBO J. , vol.20 , pp. 4311-4320
    • Luca, F.C.1    Shibuya, E.K.2    Dohrmann, C.E.3    Ruderman, J.V.4
  • 29
    • 0027972128 scopus 로고
    • Overexpression of a truncated cyclin B gene arrests Dictyostelium cell division during mitosis
    • Luo, Q., Michaelis, C., and Weeks, G. (1994). Overexpression of a truncated cyclin B gene arrests Dictyostelium cell division during mitosis. J. Cell Sci. 107, 3105-3114.
    • (1994) J. Cell Sci. , vol.107 , pp. 3105-3114
    • Luo, Q.1    Michaelis, C.2    Weeks, G.3
  • 30
    • 0025041797 scopus 로고
    • The A- and B-type cyclin-associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle
    • Minshull, J., Golsteyn, R., Hill, C.S., and Hunt, T. (1990). The A- and B-type cyclin-associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle. EMBO J. 9, 2865-2875.
    • (1990) EMBO J. , vol.9 , pp. 2865-2875
    • Minshull, J.1    Golsteyn, R.2    Hill, C.S.3    Hunt, T.4
  • 31
    • 0026266161 scopus 로고
    • Cell-cycle extracts
    • Murray, A.W. (1991). Cell-cycle extracts. Methods Cell Biol. 36, 581-605.
    • (1991) Methods Cell Biol. , vol.36 , pp. 581-605
    • Murray, A.W.1
  • 32
    • 0024978344 scopus 로고
    • The role of cyclin synthesis and degradation in the control of maturation promoting factor activity
    • Murray, A.W., Solomon, M.J., and Kirschner, M.W. (1989). The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature 339, 280-286.
    • (1989) Nature , vol.339 , pp. 280-286
    • Murray, A.W.1    Solomon, M.J.2    Kirschner, M.W.3
  • 33
    • 0026014878 scopus 로고
    • Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport
    • Pines, J., and Hunter, T. (1991). Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport. J. Cell Biol. 125, 1-17.
    • (1991) J. Cell Biol. , vol.125 , pp. 1-17
    • Pines, J.1    Hunter, T.2
  • 34
    • 0028154890 scopus 로고
    • Expression of N-terminally truncated cyclin B in the Drosophila larval brain leads to mitotic delay at late anaphase
    • Rimmington, G., Dalby, B., and Glover, D.M. (1994). Expression of N-terminally truncated cyclin B in the Drosophila larval brain leads to mitotic delay at late anaphase. J. Cell Sci. 207, 2729-2738.
    • (1994) J. Cell Sci. , vol.207 , pp. 2729-2738
    • Rimmington, G.1    Dalby, B.2    Glover, D.M.3
  • 35
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • Scheffner, M., Huibregtse, J.M., Vierstra, R.D., and Howley, P.M. (1993). The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75, 495-505.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 37
    • 0029165112 scopus 로고
    • Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B, and B3
    • Sigrist, S., Jacobs, H., Stratmann, R., and Lehner, C.F. (1995). Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B, and B3. EMBO J. 14, 4827-4838.
    • (1995) EMBO J. , vol.14 , pp. 4827-4838
    • Sigrist, S.1    Jacobs, H.2    Stratmann, R.3    Lehner, C.F.4
  • 38
    • 0025895419 scopus 로고
    • The structures of ubiquitin conjugates of yeast iso-2-cytochrome c
    • Sokolik, C.W., and Cohen, R.E. (1991). The structures of ubiquitin conjugates of yeast iso-2-cytochrome c. J. Biol. Chem. 266, 9100-9107.
    • (1991) J. Biol. Chem. , vol.266 , pp. 9100-9107
    • Sokolik, C.W.1    Cohen, R.E.2
  • 39
    • 0026544514 scopus 로고
    • Ubiquitin conjugation to cytochrome c
    • Sokolik, C.W., and Cohen, R.E. (1992). Ubiquitin conjugation to cytochrome c. J. Biol. Chem. 267, 1067-1071.
    • (1992) J. Biol. Chem. , vol.267 , pp. 1067-1071
    • Sokolik, C.W.1    Cohen, R.E.2
  • 41
    • 0023042283 scopus 로고
    • Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
    • Studier, F.W., and Moffatt, B.A. (1986). Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189, 113-130.
    • (1986) J. Mol. Biol. , vol.189 , pp. 113-130
    • Studier, F.W.1    Moffatt, B.A.2
  • 42
    • 0029025606 scopus 로고
    • The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis
    • Sudakin, V., Ganoth, D., Dahan, A., Heller, H., Hershko, J., Luca, F.C., Ruderman, J.V., and Hershko, A. (1995). The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6, 185-197.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 185-197
    • Sudakin, V.1    Ganoth, D.2    Dahan, A.3    Heller, H.4    Hershko, J.5    Luca, F.C.6    Ruderman, J.V.7    Hershko, A.8
  • 43
    • 0027158083 scopus 로고
    • Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase-to-anaphase transition in budding yeast
    • Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B., and Nasmyth, K. (1993). Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase-to-anaphase transition in budding yeast. EMBO J. 12, 1969-1978.
    • (1993) EMBO J. , vol.12 , pp. 1969-1978
    • Surana, U.1    Amon, A.2    Dowzer, C.3    McGrew, J.4    Byers, B.5    Nasmyth, K.6
  • 44
    • 0028027308 scopus 로고
    • Ubiquitindependent c-Jun degradation in vivo is mediated by the delta domain
    • Treier, M., Staszewski, L.M., and Bohmann, D. (1994). Ubiquitindependent c-Jun degradation in vivo is mediated by the delta domain. Cell 78, 787-798.
    • (1994) Cell , vol.78 , pp. 787-798
    • Treier, M.1    Staszewski, L.M.2    Bohmann, D.3
  • 45
    • 0029028237 scopus 로고
    • The CDC27Hs protein co-localizes with the CDC16Hs protein to the centrosome and mitotic spindle and is essential for the metaphase-to-anaphase transition
    • Tugendreich, S., Tomkiel, J., Earnshaw, W., and Hieter, P. (1995). The CDC27Hs protein co-localizes with the CDC16Hs protein to the centrosome and mitotic spindle and is essential for the metaphase-to-anaphase transition. Cell 81, 261-268.
    • (1995) Cell , vol.81 , pp. 261-268
    • Tugendreich, S.1    Tomkiel, J.2    Earnshaw, W.3    Hieter, P.4
  • 46
    • 0027474429 scopus 로고
    • Mitotic arrest caused by the amino terminus of Xenopus cyclin B2
    • van der Velden, H.M.W., and Lohka, M.J. (1993). Mitotic arrest caused by the amino terminus of Xenopus cyclin B2. Mol. Cell. Biol. 23, 1480-1488.
    • (1993) Mol. Cell. Biol. , vol.23 , pp. 1480-1488
    • Van Der Velden, H.M.W.1    Lohka, M.J.2
  • 48
    • 0025325445 scopus 로고
    • The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition
    • Whitfield, W.G., Gonzalez, C., Maldonado, C.G., and Glover, D.M. (1990). The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition. EMBO J. 9, 2563-2572.
    • (1990) EMBO J. , vol.9 , pp. 2563-2572
    • Whitfield, W.G.1    Gonzalez, C.2    Maldonado, C.G.3    Glover, D.M.4
  • 49
    • 0029997447 scopus 로고    scopus 로고
    • Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae
    • Yamamoto, A., Guacci, V., and Koshland, D. (1996a). Pds1p is required for faithful execution of anaphase in the yeast, Saccharomyces cerevisiae. J. Cell Biol. 133, 85-97.
    • (1996) J. Cell Biol. , vol.133 , pp. 85-97
    • Yamamoto, A.1    Guacci, V.2    Koshland, D.3
  • 50
    • 0029960782 scopus 로고    scopus 로고
    • Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s)
    • Yamamoto, A., Guacci, V., and Koshland, D. (1996b). Pds1p, an inhibitor of anaphase in budding yeast, plays a critical role in the APC and checkpoint pathway(s). J. Cell Biol. 133, 99-110.
    • (1996) J. Cell Biol. , vol.133 , pp. 99-110
    • Yamamoto, A.1    Guacci, V.2    Koshland, D.3
  • 51
    • 0030113930 scopus 로고    scopus 로고
    • Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation
    • Yu, H., King, R.W., Peters, J.-M., and Kirschner, M.W. (1996). Identification of a novel ubiquitin-conjugating enzyme involved in mitotic cyclin degradation. Curr. Biol. 6, 455-466.
    • (1996) Curr. Biol. , vol.6 , pp. 455-466
    • Yu, H.1    King, R.W.2    Peters, J.-M.3    Kirschner, M.W.4
  • 52
    • 0029924373 scopus 로고    scopus 로고
    • TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast
    • Zachariae, W., and Nasmyth, K. (1996). TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. Mol. Biol. Cell 7, 791-801.
    • (1996) Mol. Biol. Cell , vol.7 , pp. 791-801
    • Zachariae, W.1    Nasmyth, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.