Cyclin-dependent Kinases Phosphorylate Human Cdt1 and Induce Its Degradation

Journal of Biological Chemistry

Volumn 279, Issue 17, 2004, Pages 17283-17288

  Liu, Enbo ^a   Li, Xianghong ^a,b   Yan, Feng ^a   Zhao, Qiping ^a   Wu, Xiaohua ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DEGRADATION; DNA; MUTAGENESIS; SUBSTRATES;

BINDING SITES; PHOSPHORYLATION;

ENZYMES;

AMINO ACID; CULLIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLINE; F BOX PROTEIN; PROTEIN; PROTEIN SKP1; REPLICATION LICENSING FACTOR CDT1; S PHASE KINASE ASSOCIATED PROTEIN 2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CELL CYCLE S PHASE; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPLICATION; DNA REPLICATION ORIGIN; EUKARYOTIC CELL; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; UBIQUITINATION;

BINDING SITES; BLOTTING, WESTERN; CDC2-CDC28 KINASES; CELL CYCLE; CELL CYCLE PROTEINS; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 2; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA; HUMANS; IMMUNOBLOTTING; MUTATION; PHOSPHORYLATION; PLASMIDS; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; RETROVIRIDAE; S PHASE; S-PHASE KINASE-ASSOCIATED PROTEINS; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN;

EUKARYOTA; MAMMALIA;

EID: 2342442851     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300549200     Document Type: Article

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