TGF-β1 inhibits T-bet induction by IFN-γ in murine CD4 + T cells through the protein tyrosine phosphatase Src homology region 2 domain-containing phosphatase-1

Journal of Immunology

Volumn 175, Issue 9, 2005, Pages 5666-5674

  Park, Il Kyoo ^a   Shultz, Leonard D ^b   Letterio, John J ^c   Gorham, James D ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b JACKSON LABORATORY   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; JANUS KINASE; PERVANADATE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CYCLOHEXIMIDE; INTERFERON REGULATORY FACTOR 1; MESSENGER RNA; PROTEIN TYROSINE PHOSPHATASE SHP 1; PTPN6 PROTEIN, MOUSE; SIGNAL PEPTIDE; T BOX TRANSCRIPTION FACTOR; T BOX TRANSCRIPTION FACTOR TBX21; T-BOX TRANSCRIPTION FACTOR TBX21; TGFB1 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME INHIBITION; ENZYME MECHANISM; IMMUNOMODULATION; INHIBITION KINETICS; INTERFERON PRODUCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; STRAIN IDENTIFICATION; T LYMPHOCYTE ACTIVATION; TH1 CELL; TRANSCRIPTION REGULATION; ANIMAL; BAGG ALBINO MOUSE; CD4+ T LYMPHOCYTE; CELL CULTURE; DRUG ANTAGONISM; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CYCLOHEXIMIDE; INTERFERON REGULATORY FACTOR-1; INTERFERON TYPE II; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED BALB C; PROTEIN-TYROSINE-PHOSPHATASE; RNA, MESSENGER; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 27144502396     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.9.5666     Document Type: Article

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