-
1
-
-
0032842066
-
Low frequency of myeloid progenitor cells in chronic idiopathic neutropenia of adults may be related to increased production of TGF-β1 by bone marrow stromal cells
-
Papadaki H.A., Giouremou K., Eliopoulos G.D. Low frequency of myeloid progenitor cells in chronic idiopathic neutropenia of adults may be related to increased production of TGF-β1 by bone marrow stromal cells. Eur J Haematol. 63:1999;154.
-
(1999)
Eur J Haematol
, vol.63
, pp. 154
-
-
Papadaki, H.A.1
Giouremou, K.2
Eliopoulos, G.D.3
-
2
-
-
0029135331
-
Transforming growth factor β (TGF-β), a potent inhibitor of erythropoiesis: Neutralizing TGF-β antibodies show erythropoietin as a potent stimulator of murine burst-forming unit erythroid colony formation in the absence of a burst-promoting activity
-
Dybedal I., Jacobsen S.E. Transforming growth factor β (TGF-β), a potent inhibitor of erythropoiesis. neutralizing TGF-β antibodies show erythropoietin as a potent stimulator of murine burst-forming unit erythroid colony formation in the absence of a burst-promoting activity Blood. 86:1995;949.
-
(1995)
Blood
, vol.86
, pp. 949
-
-
Dybedal, I.1
Jacobsen, S.E.2
-
3
-
-
0033568229
-
Transforming growth factor-β1 (TGF-β1) induces thrombopoietin from bone marrow stromal cells, which stimulates the expression of TGF-β receptor on megakaryocytes and, in turn, renders them susceptible to suppression by TGF-β itself with high specificity
-
Sakamaki S., Hirayama Y., Matsunaga T.et al. Transforming growth factor-β1 (TGF-β1) induces thrombopoietin from bone marrow stromal cells, which stimulates the expression of TGF-β receptor on megakaryocytes and, in turn, renders them susceptible to suppression by TGF-β itself with high specificity. Blood. 94:1999;1961.
-
(1999)
Blood
, vol.94
, pp. 1961
-
-
Sakamaki, S.1
Hirayama, Y.2
Matsunaga, T.3
-
5
-
-
0029948374
-
Transforming growth factor β1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells
-
Sitnicka E., Ruscetti F.W., Priestley G.V., Wolf N.S., Bartelmez S.H. Transforming growth factor β1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells. Blood. 88:1996;82.
-
(1996)
Blood
, vol.88
, pp. 82
-
-
Sitnicka, E.1
Ruscetti, F.W.2
Priestley, G.V.3
Wolf, N.S.4
Bartelmez, S.H.5
-
6
-
-
0032521421
-
The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-β On human hematopoiesis
-
Bruno E., Horrigan S.K., Van Den Berg D.et al. The Smad5 gene is involved in the intracellular signaling pathways that mediate the inhibitory effects of transforming growth factor-β on human hematopoiesis. Blood. 91:1998;1917.
-
(1998)
Blood
, vol.91
, pp. 1917
-
-
Bruno, E.1
Horrigan, S.K.2
Van Den Berg, D.3
-
7
-
-
0031157028
-
Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+CD38-) human bone marrow progenitor cells: Distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-β And TNF-α
-
Ramsfjell V., Borge O.J., Cui L., Jacobsen S.E. Thrombopoietin directly and potently stimulates multilineage growth and progenitor cell expansion from primitive (CD34+CD38-) human bone marrow progenitor cells. distinct and key interactions with the ligands for c-kit and flt3, and inhibitory effects of TGF-β and TNF-α J Immunol. 158:1997;5169.
-
(1997)
J Immunol
, vol.158
, pp. 5169
-
-
Ramsfjell, V.1
Borge, O.J.2
Cui, L.3
Jacobsen, S.E.4
-
8
-
-
0029037953
-
The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors
-
Debili N., Wendling F., Katz A.et al. The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors. Blood. 86:1995;2516.
-
(1995)
Blood
, vol.86
, pp. 2516
-
-
Debili, N.1
Wendling, F.2
Katz, A.3
-
9
-
-
0033018375
-
Characterization of defective megakaryocytic development in patients with myelodysplastic syndromes
-
Hofmann W.K., Kalina U., Wagner S.et al. Characterization of defective megakaryocytic development in patients with myelodysplastic syndromes. Exp Hematol. 27:1999;395.
-
(1999)
Exp Hematol
, vol.27
, pp. 395
-
-
Hofmann, W.K.1
Kalina, U.2
Wagner, S.3
-
10
-
-
0029027918
-
Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors
-
Kobayashi M., Laver J.H., Kato T., Miyazaki H., Ogawa M. Recombinant human thrombopoietin (Mpl ligand) enhances proliferation of erythroid progenitors. Blood. 86:1995;2494.
-
(1995)
Blood
, vol.86
, pp. 2494
-
-
Kobayashi, M.1
Laver, J.H.2
Kato, T.3
Miyazaki, H.4
Ogawa, M.5
-
11
-
-
0029052479
-
Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets
-
Miyakawa Y., Oda A., Druker B.J.et al. Recombinant thrombopoietin induces rapid protein tyrosine phosphorylation of Janus kinase 2 and Shc in human blood platelets. Blood. 86:1995;23.
-
(1995)
Blood
, vol.86
, pp. 23
-
-
Miyakawa, Y.1
Oda, A.2
Druker, B.J.3
-
12
-
-
0029117375
-
The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases
-
Sattler M., Durstin M.A., Frank D.A.et al. The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases. Exp Hematol. 23:1995;1040.
-
(1995)
Exp Hematol
, vol.23
, pp. 1040
-
-
Sattler, M.1
Durstin, M.A.2
Frank, D.A.3
-
13
-
-
17544393392
-
The induction of megakaryocyte differentiation is accompanied by selective Ser133 phosphorylation of the transcription factor CREB in both HEL cell line and primary CD34+ cells
-
Zauli G., Gibellini D., Vitale M.et al. The induction of megakaryocyte differentiation is accompanied by selective Ser133 phosphorylation of the transcription factor CREB in both HEL cell line and primary CD34+ cells. Blood. 92:1998;472.
-
(1998)
Blood
, vol.92
, pp. 472
-
-
Zauli, G.1
Gibellini, D.2
Vitale, M.3
-
14
-
-
0028881246
-
Mechanism of inhibition of eosinophil activation by transforming growth factor-β
-
Pazdrak K., Justement L., Alam R. Mechanism of inhibition of eosinophil activation by transforming growth factor-β Inhibition of Lyn, MAP, Jak. 2(kinases and STAT1 nuclear factor. J Immunol 155):1995;4454.
-
(1995)
Inhibition of Lyn, MAP, Jak
, vol.2
, Issue.KINASES AND STAT1 NUCLEAR FACTOR. J IMMUNOL 155
, pp. 4454
-
-
Pazdrak, K.1
Justement, L.2
Alam, R.3
-
15
-
-
0031171607
-
Molecular role of TGF-β, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice
-
Han H.S., Jun H.S., Utsugi T., Yoon J.W. Molecular role of TGF-β, secreted from a new type of CD4+ suppressor T cell, NY4.2, in the prevention of autoimmune IDDM in NOD mice. J Autoimmun. 10:1997;299.
-
(1997)
J Autoimmun
, vol.10
, pp. 299
-
-
Han, H.S.1
Jun, H.S.2
Utsugi, T.3
Yoon, J.W.4
-
16
-
-
0034610729
-
Transforming growth factor β2 inhibition of hepatocyte growth factor-induced endothelial proliferation and migration
-
Manganini M., Maier J.A. Transforming growth factor β2 inhibition of hepatocyte growth factor-induced endothelial proliferation and migration. Oncogene. 19:2000;124.
-
(2000)
Oncogene
, vol.19
, pp. 124
-
-
Manganini, M.1
Maier, J.A.2
-
17
-
-
0034614271
-
TGF-β-induced matrix proteins inhibit p42/44 MAPK and JNK activation and suppress TNF-mediated IκBα degradation and NF-κB nuclear translocation in L929 fibroblasts
-
Chang N.S. TGF-β-induced matrix proteins inhibit p42/44 MAPK and JNK activation and suppress TNF-mediated IκBα degradation and NF-κB nuclear translocation in L929 fibroblasts. Biochem Biophys Res Commun. 267:2000;194.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 194
-
-
Chang, N.S.1
-
18
-
-
0032756061
-
Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-α production that is opposed by TGF-β 1 and IL-10
-
Tan J., Town T., Saxe M., Paris D., Wu Y., Mullan M. Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-α production that is opposed by TGF-β 1 and IL-10. J Immunol. 163:1999;6614.
-
(1999)
J Immunol
, vol.163
, pp. 6614
-
-
Tan, J.1
Town, T.2
Saxe, M.3
Paris, D.4
Wu, Y.5
Mullan, M.6
-
19
-
-
0020321974
-
HEL cells: A new human erythroleukemia cell line with spontaneous and induced globin expression
-
Martin P., Papayannopoulou T. HEL cells. a new human erythroleukemia cell line with spontaneous and induced globin expression Science. 216:1982;1233.
-
(1982)
Science
, vol.216
, pp. 1233
-
-
Martin, P.1
Papayannopoulou, T.2
-
20
-
-
0026704547
-
In vitro culture of common acute lymphoblastic leukemia blasts: Effects of interleukin-3, interleukin-7, and accessory cells
-
Eder M., Ottmann O.G., Hansen-Hagge T.E.et al. In vitro culture of common acute lymphoblastic leukemia blasts. effects of interleukin-3, interleukin-7, and accessory cells Blood. 79:1992;3274.
-
(1992)
Blood
, vol.79
, pp. 3274
-
-
Eder, M.1
Ottmann, O.G.2
Hansen-Hagge, T.E.3
-
21
-
-
0031685620
-
TGF-β signal transduction
-
Massague J. TGF-β signal transduction. Annu Rev Biochem. 67:1998;753.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 753
-
-
Massague, J.1
-
22
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin C.H., Miyazono K., ten Dijke P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature. 390:1997;465.
-
(1997)
Nature
, vol.390
, pp. 465
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
23
-
-
0029035985
-
Thrombopoietin, the primary regulator of platelet production
-
Kaushansky K. Thrombopoietin, the primary regulator of platelet production. Blood. 86:1995;419.
-
(1995)
Blood
, vol.86
, pp. 419
-
-
Kaushansky, K.1
-
24
-
-
0033529218
-
Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin
-
Yagi M., Ritchie K.A., Sitnicka E., Storey C., Roth G.J., Bartelmez S. Sustained ex vivo expansion of hematopoietic stem cells mediated by thrombopoietin. Proc Natl Acad Sci U S A. 96:1999;8126.
-
(1999)
Proc Natl Acad Sci U S a
, vol.96
, pp. 8126
-
-
Yagi, M.1
Ritchie, K.A.2
Sitnicka, E.3
Storey, C.4
Roth, G.J.5
Bartelmez, S.6
-
25
-
-
0029912731
-
Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines: Distinct interactions with the ligands for c-kit and FLT3
-
Ramsfjell V., Borge O.J., Veiby O.P.et al. Thrombopoietin, but not erythropoietin, directly stimulates multilineage growth of primitive murine bone marrow progenitor cells in synergy with early acting cytokines. distinct interactions with the ligands for c-kit and FLT3 Blood. 88:1996;4481.
-
(1996)
Blood
, vol.88
, pp. 4481
-
-
Ramsfjell, V.1
Borge, O.J.2
Veiby, O.P.3
-
26
-
-
0030014681
-
The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells
-
Sitnicka E., Lin N., Priestley G.V.et al. The effect of thrombopoietin on the proliferation and differentiation of murine hematopoietic stem cells. Blood. 87:1996;4998.
-
(1996)
Blood
, vol.87
, pp. 4998
-
-
Sitnicka, E.1
Lin, N.2
Priestley, G.V.3
-
27
-
-
0030671507
-
In vitro expansion of hematopoietic stem cells
-
Ogawa M., Yonemura Y., Ku H. In vitro expansion of hematopoietic stem cells. Stem Cells. 15(suppl. 1):1997;7.
-
(1997)
Stem Cells
, vol.15
, Issue.SUPPL. 1
, pp. 7
-
-
Ogawa, M.1
Yonemura, Y.2
Ku, H.3
-
28
-
-
0030039567
-
Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice
-
Ku H., Yonemura Y., Kaushansky K., Ogawa M. Thrombopoietin, the ligand for the Mpl receptor, synergizes with steel factor and other early acting cytokines in supporting proliferation of primitive hematopoietic progenitors of mice. Blood. 87:1996;4544.
-
(1996)
Blood
, vol.87
, pp. 4544
-
-
Ku, H.1
Yonemura, Y.2
Kaushansky, K.3
Ogawa, M.4
-
29
-
-
0029819701
-
Thrombopoietin stimulates megakaryocytopoiesis, myelopoiesis, and expansion of CD34+ progenitor cells from single CD34+Thy-1+Lin- primitive progenitor cells
-
Young J.C., Bruno E., Luens K.M., Wu S., Backer M., Murray L.J. Thrombopoietin stimulates megakaryocytopoiesis, myelopoiesis, and expansion of CD34+ progenitor cells from single CD34+Thy-1+Lin- primitive progenitor cells. Blood. 88:1996;1619.
-
(1996)
Blood
, vol.88
, pp. 1619
-
-
Young, J.C.1
Bruno, E.2
Luens, K.M.3
Wu, S.4
Backer, M.5
Murray, L.J.6
-
30
-
-
0030751299
-
Thrombopoietin alone stimulates the early proliferation and survival of human erythroid, myeloid and multipotential progenitors in serum-free culture
-
Yoshida M., Tsuji K., Ebihara Y.et al. Thrombopoietin alone stimulates the early proliferation and survival of human erythroid, myeloid and multipotential progenitors in serum-free culture. Br J Haematol. 98:1997;254.
-
(1997)
Br J Haematol
, vol.98
, pp. 254
-
-
Yoshida, M.1
Tsuji, K.2
Ebihara, Y.3
-
31
-
-
0032528504
-
Thrombopoietin promotes the survival of murine hematopoietic long-term reconstituting cells: Comparison with the effects of FLT3/FLK-2 ligand and interleukin-6
-
Matsunaga T., Kato T., Miyazaki H., Ogawa M. Thrombopoietin promotes the survival of murine hematopoietic long-term reconstituting cells. comparison with the effects of FLT3/FLK-2 ligand and interleukin-6 Blood. 92:1998;452.
-
(1998)
Blood
, vol.92
, pp. 452
-
-
Matsunaga, T.1
Kato, T.2
Miyazaki, H.3
Ogawa, M.4
-
32
-
-
0033568229
-
Transforming growth factor-β1 (TGF-β1) induces thrombopoietin from bone marrow stromal cells, which stimulates the expression of TGF-β receptor on megakaryocytes and, in turn, renders them susceptible to suppression by TGF-β itself with high specificity
-
Sakamaki S., Hirayama Y., Matsunaga T.et al. Transforming growth factor-β1 (TGF-β1) induces thrombopoietin from bone marrow stromal cells, which stimulates the expression of TGF-β receptor on megakaryocytes and, in turn, renders them susceptible to suppression by TGF-β itself with high specificity. Blood. 94:1999;1961.
-
(1999)
Blood
, vol.94
, pp. 1961
-
-
Sakamaki, S.1
Hirayama, Y.2
Matsunaga, T.3
-
33
-
-
0029932842
-
Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cells
-
Quentmeier H., Zaborski M., Graf G., Ludwig W.D., Drexler H.G. Expression of the receptor MPL and proliferative effects of its ligand thrombopoietin on human leukemia cells. Leukemia. 10:1996;297.
-
(1996)
Leukemia
, vol.10
, pp. 297
-
-
Quentmeier, H.1
Zaborski, M.2
Graf, G.3
Ludwig, W.D.4
Drexler, H.G.5
-
35
-
-
0032847451
-
Thrombopoietin signal transduction: Studies from cell lines and primary cells
-
Drachman J.G., Rojnuckarin P., Kaushansky K. Thrombopoietin signal transduction. studies from cell lines and primary cells Methods. 17:1999;238.
-
(1999)
Methods
, vol.17
, pp. 238
-
-
Drachman, J.G.1
Rojnuckarin, P.2
Kaushansky, K.3
-
36
-
-
0033566712
-
Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: Role in endomitosis
-
Rojnuckarin P., Drachman J.G., Kaushansky K. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes. role in endomitosis Blood. 94:1999;1273.
-
(1999)
Blood
, vol.94
, pp. 1273
-
-
Rojnuckarin, P.1
Drachman, J.G.2
Kaushansky, K.3
-
37
-
-
0029166667
-
A synthetic inhibitor of the mitogen-activated protein kinase cascade
-
Dudley D.T., Pang L., Decker S.J., Bridges A.J., Saltiel A.R. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A. 92:1995;7686.
-
(1995)
Proc Natl Acad Sci U S a
, vol.92
, pp. 7686
-
-
Dudley, D.T.1
Pang, L.2
Decker, S.J.3
Bridges, A.J.4
Saltiel, A.R.5
-
38
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan N., Grunberger T., Dadi H.et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature. 379:1996;645.
-
(1996)
Nature
, vol.379
, pp. 645
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
-
39
-
-
0031453394
-
The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway
-
Dorsch M., Fan P.D., Danial N.N., Rothman P.B., Goff S.P. The thrombopoietin receptor can mediate proliferation without activation of the Jak-STAT pathway. J Exp Med. 186:1997;1947.
-
(1997)
J Exp Med
, vol.186
, pp. 1947
-
-
Dorsch, M.1
Fan, P.D.2
Danial, N.N.3
Rothman, P.B.4
Goff, S.P.5
-
40
-
-
0032829719
-
A thrombopoietin receptor mutant deficient in Jak-STAT activation mediates proliferation but not differentiation in UT-7 cells
-
Dorsch M., Danial N.N., Rothman P.B., Goff S.P. A thrombopoietin receptor mutant deficient in Jak-STAT activation mediates proliferation but not differentiation in UT-7 cells. Blood. 94:1999;2676.
-
(1999)
Blood
, vol.94
, pp. 2676
-
-
Dorsch, M.1
Danial, N.N.2
Rothman, P.B.3
Goff, S.P.4
-
41
-
-
0033120870
-
Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines
-
Liu R.Y., Fan C., Garcia R., Jove R., Zuckerman K.S. Constitutive activation of the JAK2/STAT5 signal transduction pathway correlates with growth factor independence of megakaryocytic leukemic cell lines. Blood. 93:1999;2369.
-
(1999)
Blood
, vol.93
, pp. 2369
-
-
Liu, R.Y.1
Fan, C.2
Garcia, R.3
Jove, R.4
Zuckerman, K.S.5
|