Downregulation of IL-6-induced STAT3 tyrosine phosphorylation by TGF-β1 is mediated by caspase-dependent and -independent processes

Leukemia

Volumn 16, Issue 4, 2002, Pages 675-682

  Wierenga, A T J ^a,b   Schuringa, J J ^a,b   Eggen, B J L ^b   Kruijer, W ^b   Vellenga, E ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b University of Groningen Center of Biological Sciences Haren   (Netherlands)

Author keywords

Apoptosis; Caspases; IL 6; STAT3; TGF 1

Indexed keywords

BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BINDING PROTEIN; CASPASE; CASPASE 3; CASPASE INHIBITOR; CELL PROTEIN; CYTOTOXIC AGENT; ENZYME ANTIBODY; ETOPOSIDE; EXTRACELLULAR REGULATED KINASE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 6; JANUS KINASE 1; JANUS KINASE 2; LIPOCORTIN 5; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROPIDIUM IODIDE; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN ANTIBODY; PROTEIN TYK2; PROTEIN TYROSINE KINASE; RECOMBINANT INTERLEUKIN 6; SMAD3 PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; SUPPRESSOR OF CYTOKINE SIGNALING PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACUTE GRANULOCYTIC LEUKEMIA; APOPTOSIS; BLAST CELL; CELL COMMUNICATION; CELL CULTURE; CONTROLLED STUDY; ENZYME ANALYSIS; HUMAN; HUMAN CELL; INCUBATION TIME; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; REVIEW; SIGNAL TRANSDUCTION;

EID: 85014210290     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402425     Document Type: Review

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