Modelling enzyme reaction mechanisms, specificity and catalysis

Drug Discovery Today

Volumn 10, Issue 20, 2005, Pages 1393-1402

  Mulholland, Adrian J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; CYTOCHROME P450; ENZYME; GLUTATHIONE TRANSFERASE;

AB INITIO CALCULATION; ACYLATION; ANTIBIOTIC RESISTANCE; CATALYSIS; CHEMICAL BOND; CHEMICAL REACTION; CRYSTAL STRUCTURE; DENSITY FUNCTIONAL THEORY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME SPECIFICITY; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HYDROGEN BOND; MOLECULAR MECHANICS; MOLECULAR MODEL; OXIDATION; PKA; PREDICTION; QUANTUM CHEMISTRY; QUANTUM MECHANICS; REVIEW; SIMULATION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

CATALYSIS; ENZYMES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; QUANTUM THEORY; SUBSTRATE SPECIFICITY; TERMINOLOGY;

EID: 27144494583     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(05)03611-1     Document Type: Review

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