Transmembrane domains 1 and 3 of the glycine transporter GLYT1 contain structural determinants of N[3-(4′-fluorophenyl)-3-(4′- phenylphenoxy)-propyl]sarcosine specificity

Neuropharmacology

Volumn 49, Issue 6, 2005, Pages 922-934

  Núñez, Enrique ^a   Martínez Maza, Rodrigo ^a   Geerlings, Arjan ^a   Aragón, Carmen ^a   López Corcuera, Beatriz ^a  

^a CSIC   (Spain)

Author keywords

Binding; Chimeras; Glycine; GLYTs; N 3 (4 Fluorophenyl) 3 (4 phenylphenoxy) propyl sarcosine; Stable cells; Transport inhibition

Indexed keywords

GLYCINE; GLYCINE TRANSPORTER; MEMBRANE PROTEIN; N [3 (4' FLUOROPHENYL) 3 (4' PHENYLPHENOXY)PROPYL]SARCOSINE; NEUROTRANSMITTER; SARCOSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHIMERA; CONTROLLED STUDY; DRUG INHIBITION; HUMAN; HUMAN CELL; KINETICS; MUTANT; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REDUCTION; REGULATORY MECHANISM; SYNAPSE;

ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CELL LINE; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; GLYCINE; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS; PROTEIN STRUCTURE, TERTIARY; SARCOSINE; SUBCELLULAR FRACTIONS; TIME FACTORS; TRITIUM;

EID: 26944477401     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2005.07.010     Document Type: Article

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